MicroRNAs Regulating Pathophysiological Processes in Obesity: The Impact of Exercise Training

[1]  L. Gómez-Quiroz,et al.  A low-intensity lifelong exercise routine changes miRNA expression in aging and prevents osteosarcopenic obesity by modulating inflammation. , 2022, Archives of gerontology and geriatrics.

[2]  A. Pretorius,et al.  Changes in subcutaneous adipose tissue microRNA expression in response to exercise training in African women with obesity , 2022, Scientific Reports.

[3]  L. Roever,et al.  The Epigenetic Role of MiRNAs in Endocrine Crosstalk Between the Cardiovascular System and Adipose Tissue: A Bidirectional View , 2022, Frontiers in Cell and Developmental Biology.

[4]  Alex Cleber Improta-Caria.  Exercício Físico e MicroRNAs: Mecanismos Moleculares na Hipertensão e Infarto do Miocárdio , 2022, Arquivos brasileiros de cardiologia.

[5]  Yaohui Nie,et al.  Obesity and exercise training alter inflammatory pathway skeletal muscle small extracellular vesicle microRNAs , 2022, Experimental physiology.

[6]  P. Arner,et al.  Subcutaneous adipose tissue expansion mechanisms are similar in early and late onset overweight/obesity , 2022, International Journal of Obesity.

[7]  Abeer M. Mahmoud.  An Overview of Epigenetics in Obesity: The Role of Lifestyle and Therapeutic Interventions , 2022, International journal of molecular sciences.

[8]  L. Roever,et al.  MicroRNAs in type 2 diabetes mellitus: potential role of physical exercise. , 2022, Reviews in cardiovascular medicine.

[9]  L. Ren,et al.  Liraglutide suppresses obesity and promotes browning of white fat via miR-27b in vivo and in vitro , 2021, The Journal of international medical research.

[10]  G. Lo Coco,et al.  Effects of COVID‐19 lockdown on eating disorders and obesity: A systematic review and meta‐analysis , 2021, European eating disorders review : the journal of the Eating Disorders Association.

[11]  A. Improta-Caria,et al.  Physical Exercise and Immune System: Perspectives on the COVID-19 pandemic. , 2021, Revista da Associacao Medica Brasileira.

[12]  Roque Aras Júnior,et al.  Treinamento com Exercício Físico e Doença de Chagas: Função Potencial dos MicroRNAs , 2021, Arquivos Brasileiros de Cardiologia.

[13]  Dechen Liu,et al.  The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice , 2021, Nature Communications.

[14]  A. Improta-Caria,et al.  Physical exercise consequences on memory in obesity: A systematic review , 2021, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[15]  Xu Yan,et al.  The Role of Exercise, Diet, and Cytokines in Preventing Obesity and Improving Adipose Tissue , 2021, Nutrients.

[16]  Yuan Luo,et al.  Exercise retards ongoing adipose tissue fibrosis in diet-induced obese mice , 2021, Endocrine connections.

[17]  Ursula A White,et al.  Exercise reduced the formation of new adipocytes in the adipose tissue of mice in vivo , 2021, PloS one.

[18]  Roque Aras Júnior,et al.  The effects of the COVID-19 pandemic on levels of physical fitness. , 2020, Revista da Associacao Medica Brasileira.

[19]  Alexis A Gonzalez,et al.  MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy , 2020, Cardiovascular Diabetology.

[20]  C. Kahn,et al.  Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise , 2020, Proceedings of the National Academy of Sciences.

[21]  L. Oyama,et al.  Aerobic exercise training regulates serum extracellular vesicle miRNAs linked to obesity to promote their beneficial effects in mice. , 2020, American journal of physiology. Endocrinology and metabolism.

[22]  A. Improta-Caria,et al.  Modulation of MicroRNAs as a Potential Molecular Mechanism Involved in the Beneficial Actions of Physical Exercise in Alzheimer Disease , 2020, International journal of molecular sciences.

[23]  M. Zaiou.  The Emerging Role and Promise of Circular RNAs in Obesity and Related Metabolic Disorders , 2020, Cells.

[24]  Yi Li,et al.  Circular RNA SAMD4A controls adipogenesis in obesity through the miR-138-5p/EZH2 axis , 2020, Theranostics.

[25]  Michael E. Hall,et al.  Obesity, Hypertension, and Cardiac Dysfunction , 2020, Circulation research.

[26]  Yoke Keong Yong,et al.  Endothelial Dysfunction in Obesity-Induced Inflammation: Molecular Mechanisms and Clinical Implications , 2020, Biomolecules.

[27]  F. Beguinot,et al.  Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes , 2020, Frontiers in Physiology.

[28]  Jessica L. Barrett,et al.  Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity. , 2019, The New England journal of medicine.

[29]  Michael D. Schmidt,et al.  Exercise effects on arterial stiffness and heart health in children with excess weight: The SMART RCT , 2019, International Journal of Obesity.

[30]  E. Melanson,et al.  The effects of exercise session timing on weight loss and components of energy balance: midwest exercise trial 2 , 2019, International Journal of Obesity.

[31]  P. Formisano,et al.  Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications , 2019, International journal of molecular sciences.

[32]  C. Drevon,et al.  Effects of long-term exercise on plasma adipokine levels and inflammation-related gene expression in subcutaneous adipose tissue in sedentary dysglycaemic, overweight men and sedentary normoglycaemic men of healthy weight , 2019, Diabetologia.

[33]  F. Milagro,et al.  DNA methylation markers in obesity, metabolic syndrome, and weight loss , 2019, Epigenetics.

[34]  M. Yau,et al.  Role of Histone Acetylation and Methylation in Obesity , 2019, Current Pharmacology Reports.

[35]  F. Magkos,et al.  The epidemiology of obesity. , 2019, Metabolism: clinical and experimental.

[36]  C. Nonaka,et al.  Exercise Training-Induced Changes in MicroRNAs: Beneficial Regulatory Effects in Hypertension, Type 2 Diabetes, and Obesity , 2018, International journal of molecular sciences.

[37]  T. Fernandes,et al.  Exercise training prevents obesity-associated disorders: Role of miRNA-208a and MED13 , 2018, Molecular and Cellular Endocrinology.

[38]  Jiandie D. Lin,et al.  Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis , 2018, Nature Communications.

[39]  A. Pandey,et al.  An Overview and Update on Obesity and the Obesity Paradox in Cardiovascular Diseases. , 2018, Progress in cardiovascular diseases.

[40]  C. DeSouza,et al.  Influence of Overweight and Obesity on Circulating Inflammation-Related microRNA. , 2018, MicroRNA.

[41]  Li Xu,et al.  MicroRNA-410-5p exacerbates high-fat diet-induced cardiac remodeling in mice in an endocrine fashion , 2018, Scientific Reports.

[42]  T. Fernandes,et al.  Exercise Training Restores the Cardiac Microrna-16 Levels Preventing Microvascular Rarefaction in Obese Zucker Rats , 2018, Obesity Facts.

[43]  J. Liao,et al.  miR-214 and miR-126 were associated with restoration of endothelial function in obesity after exercise and dietary intervention , 2018 .

[44]  C. Negrão,et al.  Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats , 2017, Oxidative medicine and cellular longevity.

[45]  C. Negrão,et al.  Obesity Downregulates MicroRNA-126 Inducing Capillary Rarefaction in Skeletal Muscle: Effects of Aerobic Exercise Training , 2017, Oxidative medicine and cellular longevity.

[46]  B. Wolfe,et al.  Treatment of Obesity: Weight Loss and Bariatric Surgery. , 2016, Circulation research.

[47]  L. Goodyear,et al.  Exercise regulation of adipose tissue , 2016, Adipocyte.

[48]  Lei Yang,et al.  MiR-26b modulates insulin sensitivity in adipocytes by interrupting the PTEN/PI3K/AKT pathway , 2015, International Journal of Obesity.

[49]  S. Tyagi,et al.  Exercise ameliorates high fat diet induced cardiac dysfunction by increasing interleukin 10 , 2015, Front. Physiol..

[50]  I. Komuro,et al.  ENPP2 Contributes to Adipose Tissue Expansion and Insulin Resistance in Diet-Induced Obesity , 2014, Diabetes.

[51]  Isabelle Lys,et al.  Multi-omic integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in Type 2 diabetic obesity. , 2014, Physiological genomics.

[52]  Lei Yang,et al.  MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity , 2014, Molecular and Cellular Endocrinology.

[53]  C. Jung,et al.  MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade , 2013, EMBO molecular medicine.

[54]  Chad E. Grueter,et al.  A Cardiac MicroRNA Governs Systemic Energy Homeostasis by Regulation of MED13 , 2012, Cell.

[55]  T. Fernandes,et al.  Exercise Training Prevents the Microvascular Rarefaction in Hypertension Balancing Angiogenic and Apoptotic Factors: Role of MicroRNAs-16, -21, and -126 , 2012, Hypertension.

[56]  A. Kim,et al.  miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression. , 2010, Biochemical and biophysical research communications.

[57]  C. Dani,et al.  microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma. , 2009, Biochemical and biophysical research communications.

[58]  V. Kim,et al.  Regulation of microRNA biogenesis , 2014, Nature Reviews Molecular Cell Biology.

[59]  Junghyo Jo,et al.  Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth , 2009, PLoS Comput. Biol..

[60]  H. Lodish,et al.  MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity , 2009, Diabetes.

[61]  Ru-Fang Yeh,et al.  miR-126 regulates angiogenic signaling and vascular integrity. , 2008, Developmental cell.

[62]  Joshua T. Mendell,et al.  MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1 , 2008, Proceedings of the National Academy of Sciences.

[63]  J. Flier,et al.  Regulated Production of a Peroxisome Proliferator-activated Receptor-γ Ligand during an Early Phase of Adipocyte Differentiation in 3T3-L1 Adipocytes* , 2004, Journal of Biological Chemistry.

[64]  R. Ringseis,et al.  Metabolic signals and innate immune activation in obesity and exercise. , 2015, Exercise immunology review.

[65]  T. Marwick,et al.  Obesity cardiomyopathy: pathogenesis and pathophysiology , 2007, Nature Clinical Practice Cardiovascular Medicine.

[66]  E. Schiffrin,et al.  Endothelial dysfunction. , 2004, Journal of the American Society of Nephrology : JASN.