Hierarchical organization of cognitive memory.

This paper addresses the question of the organization of memory processes within the medial temporal lobe. Evidence obtained in patients with late-onset amnesia resulting from medial temporal pathology has given rise to two opposing interpretations of the effects of such damage on long-term cognitive memory. One view is that cognitive memory, including memory for both facts and events, is served in a unitary manner by the hippocampus and its surrounding cortices; the other is that the basic function affected in amnesia is event memory, the memory for factual material often showing substantial preservation. Recent findings in patients with amnesia resulting from relatively selective hippocampal damage sustained early in life suggest a possible reconciliation of the two views. The new findings suggest that the hippocampus may be especially important for event as opposed to fact memory, with the surrounding cortical areas contributing to both. Evidence from neuroanatomical and neurobehavioural studies in monkeys is presented in support of this proposal.

[1]  D. Amaral,et al.  The entorhinal cortex of the monkey: II. Cortical afferents , 1987, The Journal of comparative neurology.

[2]  F. Wood,et al.  Long-term follow-up of a childhood amnesic syndrome , 1989, Brain and Cognition.

[3]  B. Milner Further analysis of the hippocampal amnesic syndrome: 14-year follow-up of HM , 1996 .

[4]  M Mishkin,et al.  Amygdalectomy impairs crossmodal association in monkeys. , 1985, Science.

[5]  M. Mishkin,et al.  Differential effects of early hippocampal pathology on episodic and semantic memory. , 1997, Science.

[6]  M. Mishkin,et al.  Hippocampectomized monkeys can remember one place but not two , 1993, Neuropsychologia.

[7]  A Connelly,et al.  The spectrum of hippocampal sclerosis: A quantitative magnetic resonance imaging study , 1997, Annals of neurology.

[8]  R. Ratcliff,et al.  A critical evaluation of the semantic-episodic distinction. , 1986, Journal of experimental psychology. Learning, memory, and cognition.

[9]  B. Milner,et al.  Further analysis of the hippocampal amnesic syndrome: 14-year follow-up study of H.M.☆ , 1968 .

[10]  Daniel L. Schacter,et al.  Computer learning by memory-impaired patients: Acquisition and retention of complex knowledge , 1986, Neuropsychologia.

[11]  W. Scoville,et al.  LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS , 1957, Journal of neurology, neurosurgery, and psychiatry.

[12]  D. Pandya,et al.  Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. I. Temporal lobe afferents , 1975, Brain Research.

[13]  L R Squire,et al.  Impaired priming of new associations in amnesia. , 1989, Journal of experimental psychology. Learning, memory, and cognition.

[14]  L. Squire,et al.  Structure and function of declarative and nondeclarative memory systems. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[15]  D. Amaral,et al.  Lesions of the perirhinal and parahippocampal cortices in the monkey produce long-lasting memory impairment in the visual and tactual modalities , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[16]  Mortimer Mishkin,et al.  Evidence for the sequential participation of inferior temporal cortex and amygdala in the acquisition of stimulus-reward associations , 1981, Behavioural Brain Research.

[17]  D. Amaral,et al.  Lesions of perirhinal and parahippocampal cortex that spare the amygdala and hippocampal formation produce severe memory impairment , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[18]  B T Hyman,et al.  H. M.’s Medial Temporal Lobe Lesion: Findings from Magnetic Resonance Imaging , 1997, The Journal of Neuroscience.

[19]  L. Squire,et al.  Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[20]  D. Amaral,et al.  Perirhinal and parahippocampal cortices of the macaque monkey: Cortical afferents , 1994, The Journal of comparative neurology.

[21]  Endel Tulving,et al.  The Role of Repetition and Associative Interference in New Semantic Learning in Amnesia: A Case Experiment , 1993, Journal of Cognitive Neuroscience.

[22]  E. Tulving,et al.  Memory, amnesia, and the episodic/semantic distinction , 1982 .

[23]  L R Squire,et al.  On the acquisition of new declarative knowledge in amnesia. , 1995, Behavioral neuroscience.

[24]  Seth J. Ramus,et al.  Severity of memory impairment in monkeys as a function of locus and extent of damage within the medial temporal lobe memory system , 1994, Hippocampus.

[25]  A Connelly,et al.  Detection of hippocampal pathology in intractable partial epilepsy , 1993, Neurology.

[26]  M. Victor,et al.  Amnesia due to Lesions Confined to the Hippocampus: A Clinical-Pathologic Study , 1990, Journal of Cognitive Neuroscience.

[27]  L. Squire,et al.  Childhood amnesia and distinctions between forms of memory: A comment on Wood, Brown, and Felton , 1990, Brain and Cognition.

[28]  L. Squire,et al.  Enduring memory impairment in monkeys after ischemic damage to the hippocampus , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[29]  E. Tulving,et al.  Long-lasting perceptual priming and semantic learning in amnesia: a case experiment. , 1991, Journal of experimental psychology. Learning, memory, and cognition.

[30]  Endel Tulving,et al.  Organization of memory: Quo vadis? , 1995 .

[31]  L. Squire,et al.  Damage to the perirhinal cortex exacerbates memory impairment following lesions to the hippocampal formation , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[32]  D. Amaral,et al.  Three Cases of Enduring Memory Impairment after Bilateral Damage Limited to the Hippocampal Formation , 1996, The Journal of Neuroscience.

[33]  M. Mishkin,et al.  Visual recognition in monkeys following rhinal cortical ablations combined with either amygdalectomy or hippocampectomy , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[34]  Deepak N. Pandya,et al.  Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. III. Efferent connections , 1975, Brain Research.

[35]  M. Mishkin,et al.  Effects on visual recognition of combined and separate ablations of the entorhinal and perirhinal cortex in rhesus monkeys , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[36]  L. Squire The neuropsychology of human memory. , 1982, Annual review of neuroscience.

[37]  M Mishkin,et al.  Neural substrates of visual stimulus-stimulus association in rhesus monkeys , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[38]  Deepak N. Pandya,et al.  Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. II. Frontal lobe afferents , 1975, Brain Research.

[39]  M. Mishkin,et al.  A selective mnemonic role for the hippocampus in monkeys: memory for the location of objects , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[40]  A Connelly,et al.  Lateralization of brain function in childhood revealed by magnetic resonance spectroscopy , 1996, Neurology.

[41]  J. A. Horel,et al.  Cortical afferents to behaviorally defined regions of the inferior temporal and parahippocampal gyri as demonstrated by WGA‐HRP , 1992, The Journal of comparative neurology.

[42]  W. Suzuki,et al.  Topographic organization of the reciprocal connections between the monkey entorhinal cortex and the perirhinal and parahippocampal cortices , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[43]  N. Cohen,et al.  The impaired learning of semantic knowledge following bilateral medial temporal-lobe resection , 1988, Brain and Cognition.

[44]  G. Bonin,et al.  The neocortex of Macaca mulatta , 1947 .

[45]  T. Powell,et al.  An anatomical study of converging sensory pathways within the cerebral cortex of the monkey. , 1970, Brain : a journal of neurology.