Patient‐specific parameterised cam geometry in finite element models of femoroacetabular impingement of the hip

Background: Impingement resulting in soft tissue damage has been observed in hips with abnormal morphologies. Geometric parameterisation can be used to automatically generate a range of bone geometries for use in computational models, including femurs with cam deformity on the femoral neck. Methods: This study verified patient‐specific parametric finite element models of 20 patients with cam deformity (10 female, 10 male) through comparison to their patient‐specific segmentation‐based equivalents. The parameterisation system was then used to generate further models with parametrically defined geometry to investigate morphological changes in both the femur and acetabulum and their effects on impingement. Findings: Similar findings were observed between segmentation‐based and parametric models when assessing soft tissue strains under impingement conditions, resulting from high flexion and internal rotations. Parametric models with cam morphology demonstrated that clinically used alpha angles should not be relied on for estimating impingement severity since planar views do not capture the full three‐dimensional geometry of the joint. Furthermore, the parametric approach allowed study of labral shape changes, indicating higher strains can result from bony overcoverage. Interpretation: The position of cams, as well as their size, can affect the level of soft tissue strain occurring in the hip. This highlights the importance of reporting the full details of three‐dimensional geometry used when developing computational models of the hip joint and suggests that it could be beneficial to stratify the patient population when considering treatment options, since certain morphologies may be at greater risk of elevated soft tissue strain.

[1]  Cheng-Kung Cheng,et al.  The influence of mechanical properties of subchondral plate, femoral head and neck on dynamic stress distribution of the articular cartilage. , 2005, Medical engineering & physics.

[2]  P. Banerjee,et al.  Femoroacetabular impingement: a review of diagnosis and management , 2011, Current reviews in musculoskeletal medicine.

[3]  Gerard A Ateshian,et al.  Equivalence between short-time biphasic and incompressible elastic material responses. , 2007, Journal of biomechanical engineering.

[4]  R. Ganz,et al.  Hip morphology influences the pattern of damage to the acetabular cartilage: femoroacetabular impingement as a cause of early osteoarthritis of the hip. , 2005, The Journal of bone and joint surgery. British volume.

[5]  C. Pfirrmann,et al.  Cam and pincer femoroacetabular impingement: characteristic MR arthrographic findings in 50 patients. , 2006, Radiology.

[6]  Alison C Jones,et al.  Geometric parameterisation of pelvic bone and cartilage in contact analysis of the natural hip: An initial study , 2015, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[7]  Benjamin J. Ellis,et al.  Validation of finite element predictions of cartilage contact pressure in the human hip joint. , 2008, Journal of biomechanical engineering.

[8]  Christopher L Peters,et al.  Correlations between the alpha angle and femoral head asphericity: Implications and recommendations for the diagnosis of cam femoroacetabular impingement. , 2014, European journal of radiology.

[9]  Fei Hu,et al.  Contributions of non-spherical hip joint cartilage surface to hip joint contact stress , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[10]  Olufemi R. Ayeni,et al.  Alpha angle correction in femoroacetabular impingement , 2014, Knee Surgery, Sports Traumatology, Arthroscopy.

[11]  Alison C Jones,et al.  The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage. , 2017, Journal of the mechanical behavior of biomedical materials.

[12]  Edmundo Balsemão Pires,et al.  Finite element simulations of a hip joint with femoroacetabular impingement , 2014, Computer methods in biomechanics and biomedical engineering.

[13]  A. Weber,et al.  The Natural History of Femoroacetabular Impingement , 2015, Front. Surg..

[14]  W. Petersen,et al.  Structure and vascularization of the acetabular labrum with regard to the pathogenesis and healing of labral lesions , 2003, Archives of Orthopaedic and Trauma Surgery.

[15]  Benjamin J. Ellis,et al.  Effects of Idealized Joint Geometry on Finite Element Predictions of Cartilage Contact Stresses in the Hip , 2022 .

[16]  G. Bergmann,et al.  Hip contact forces and gait patterns from routine activities. , 2001, Journal of biomechanics.

[17]  Jeffrey A Weiss,et al.  Subject-specific analysis of joint contact mechanics: application to the study of osteoarthritis and surgical planning. , 2013, Journal of biomechanical engineering.

[18]  Scott A. Rodeo,et al.  The Basic Science of Articular Cartilage , 2009, Sports health.

[19]  Alison C Jones,et al.  Three‐dimensional assessment of impingement risk in geometrically parameterised hips compared with clinical measures , 2017, International journal for numerical methods in biomedical engineering.

[20]  J. Le Huec,et al.  Normative 3D acetabular orientation measurements by the low-dose EOS imaging system in 102 asymptomatic subjects in standing position: Analyses by side, gender, pelvic incidence and reproducibility. , 2017, Orthopaedics & traumatology, surgery & research : OTSR.

[21]  M. Lamontagne,et al.  Hip Joint Stresses Due to Cam-Type Femoroacetabular Impingement: A Systematic Review of Finite Element Simulations , 2016, PloS one.

[22]  R. Ganz,et al.  Femoroacetabular impingement: a cause for osteoarthritis of the hip. , 2003, Clinical orthopaedics and related research.

[23]  B. F. Morrey,et al.  Femoroacetabular Impingement: Radiographic Diagnosis—What the Radiologist Should Know , 2008 .

[24]  O. Mei-Dan,et al.  Lateral Acetabular Coverage Predicts the Size of the Hip Labrum , 2016, The American journal of sports medicine.

[25]  Steve A Maas,et al.  Finite element simulation of articular contact mechanics with quadratic tetrahedral elements. , 2016, Journal of biomechanics.

[26]  Stephen J Ferguson,et al.  The effects of impingement and dysplasia on stress distributions in the hip joint during sitting and walking: A finite element analysis , 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[27]  J. Tong,et al.  Hip joint degeneration due to cam impingement: a finite element analysis , 2016, Computer methods in biomechanics and biomedical engineering.

[28]  P. Beaulé,et al.  Incidence of Hip Pain in a Prospective Cohort of Asymptomatic Volunteers , 2014, The American journal of sports medicine.

[29]  A. Grant,et al.  The labrum: structure, function, and injury with femoro-acetabular impingement , 2012, Journal of children's orthopaedics.

[30]  F. Ergen,et al.  CT assessment of asymptomatic hip joints for the background of femoroacetabular impingement morphology. , 2014, Diagnostic and interventional radiology.

[31]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.