Molecular and cellular mechanisms of T lymphocyte apoptosis.
暂无分享，去创建一个
[1] G. Kroemer,et al. The mitochondrial death/life regulator in apoptosis and necrosis. , 1998, Annual review of physiology.
[2] N. Suzuki,et al. Primary Structure and Differential Gene Expression of Three Membrane Forms of Guanylyl Cyclase Found in the Eye of the TeleostOryzias latipes * , 1997, The Journal of Biological Chemistry.
[3] D. Kufe,et al. Caspase-3-mediated Cleavage of Protein Kinase C θ in Induction of Apoptosis* , 1997, The Journal of Biological Chemistry.
[4] Guido Kroemer,et al. Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution , 1997, Cell Death and Differentiation.
[5] P. Nicotera,et al. Energy supply and the shape of death in neurons and lymphoid cells , 1997, Cell Death and Differentiation.
[6] I. Guénal,et al. Bcl-2 and Hsp27 act at different levels to suppress programmed cell death , 1997, Oncogene.
[7] G. Kroemer,et al. The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis , 1997, The Journal of experimental medicine.
[8] G. Kroemer,et al. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition , 1997, FEBS letters.
[9] G M Bokoch,et al. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. , 1997, Science.
[10] D. Newmeyer,et al. Temporal Phases in Apoptosis Defined by the Actions of Src Homology 2 Domains, Ceramide, Bcl-2, Interleukin-1β Converting Enzyme Family Proteases, and a Dense Membrane Fraction , 1997, The Journal of cell biology.
[11] Guido Kroemer,et al. The proto-oncogene Bcl-2 and its role in regulating apoptosis , 1997, Nature Medicine.
[12] H. Sakamoto,et al. The Negative Signaling Molecule SH2 Domain-containing Inositol-Polyphosphate 5-Phosphatase (SHIP) Binds to the Tyrosine-phosphorylated β Subunit of the High Affinity IgE Receptor* , 1997, The Journal of Biological Chemistry.
[13] F. Fassy,et al. Evidence for CPP32 Activation in the Absence of Apoptosis during T Lymphocyte Stimulation* , 1997, The Journal of Biological Chemistry.
[14] W. J. Boyle,et al. ATAR, a Novel Tumor Necrosis Factor Receptor Family Member, Signals through TRAF2 and TRAF5* , 1997, The Journal of Biological Chemistry.
[15] G. Kroemer,et al. Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis. , 1997, Journal of immunology.
[16] Matthias Mann,et al. FLICE is activated by association with the CD95 death‐inducing signaling complex (DISC) , 1997, The EMBO journal.
[17] Y. Tsujimoto,et al. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. , 1997, Cancer research.
[18] J C Reed,et al. Channel formation by antiapoptotic protein Bcl-2. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[19] P. Warne,et al. Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras , 1997, Cell.
[20] R. Moreno-Sánchez,et al. The mitochondrial membrane permeability transition induced by inorganic phosphate or inorganic arsenate. A comparative study. , 1997, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
[21] H. Karasuyama,et al. Exposure of phosphatidylethanolamine on the surface of apoptotic cells. , 1997, Experimental cell research.
[22] G. Evan,et al. Human Bak induces cell death in Schizosaccharomyces pombe with morphological changes similar to those with apoptosis in mammalian cells , 1997, Molecular and cellular biology.
[23] M. Zvelebil,et al. p110δ, a novel phosphoinositide 3-kinase in leukocytes , 1997 .
[24] A. Colell,et al. Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species , 1997, The Journal of Biological Chemistry.
[25] P. Nicotera,et al. Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis , 1997, The Journal of experimental medicine.
[26] K. Kinnally,et al. Tim23, a Protein Import Component of the Mitochondrial Inner Membrane, Is Required for Normal Activity of the Multiple Conductance Channel, MCC , 1997, The Journal of cell biology.
[27] Xiaodong Wang,et al. DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis , 1997, Cell.
[28] G Shimamoto,et al. Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density , 1997, Cell.
[29] P. Nicotera,et al. Apoptosis in the absence of poly-(ADP-ribose) polymerase. , 1997, Biochemical and biophysical research communications.
[30] F. Shibasaki,et al. Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2 , 1997, Nature.
[31] C. Thompson,et al. Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[32] J. Cohen,et al. Calpain, an upstream regulator of thymocyte apoptosis. , 1997, Journal of immunology.
[33] R. Kamen,et al. Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production , 1997, Nature.
[34] B. Zhivotovsky,et al. Two different proteases are involved in the proteolysis of lamin during apoptosis. , 1997, Biochemical and biophysical research communications.
[35] H. Masutani,et al. Mg2+- or Mn2+-dependent endonuclease activities of human myeloid leukemia cells capable of producing nucleosomal-size DNA fragmentation. , 1997, Biochemical and biophysical research communications.
[36] K. Higashi,et al. Role of Tyrosine Phosphorylation of HS1 in B Cell Antigen Receptor-mediated Apoptosis , 1997, The Journal of experimental medicine.
[37] Arul M. Chinnaiyan,et al. The Receptor for the Cytotoxic Ligand TRAIL , 1997, Science.
[38] R. Kolesnick,et al. Kinase Suppressor of Ras Is Ceramide-Activated Protein Kinase , 1997, Cell.
[39] P. Hawkins,et al. The Gβγ Sensitivity of a PI3K Is Dependent upon a Tightly Associated Adaptor, p101 , 1997, Cell.
[40] J. Tschopp,et al. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors , 1997, Nature.
[41] Tamara Hirsch,et al. Mitochondrial Implication in Accidental and Programmed Cell Death: Apoptosis and Necrosis , 1997, Journal of bioenergetics and biomembranes.
[42] T. Patel,et al. Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat , 1997, Hepatology.
[43] H. Pircher,et al. Alterations in the level of CD45 surface expression affect the outcome of thymic selection. , 1997, Journal of immunology.
[44] L. Montagnier,et al. Purification and characterization of Mycoplasma penetrans Ca2+/Mg2+-dependent endonuclease , 1997, Journal of bacteriology.
[45] M. Poot,et al. Detection of apoptosis in live cells by MitoTracker red CMXRos and SYTO dye flow cytometry. , 1997, Cytometry.
[46] T. Mak,et al. T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45. , 1997, Journal of immunology.
[47] J. Cidlowski,et al. Utilization of an in vitro assay to evaluate chromatin degradation by candidate apoptotic nucleases , 1997, Cell Death and Differentiation.
[48] A. Fraser,et al. CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9 , 1997, Current Biology.
[49] C. Piantadosi,et al. Release of cytochrome c from liver mitochondria during permeability transition. , 1997, Biochemical and biophysical research communications.
[50] B. Druker,et al. RAFTK, a Novel Member of the Focal Adhesion Kinase Family, Is Phosphorylated and Associates with Signaling Molecules upon Activation of Mature T Lymphocytes , 1997, The Journal of experimental medicine.
[51] Daniel E. Johnson,et al. Fas stimulation induces RB dephosphorylation and proteolysis that is blocked by inhibitors of the ICE protease family , 1997, Journal of cellular biochemistry.
[52] R. Flavell,et al. Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotype. , 1997, Journal of immunology.
[53] U. Deuschle,et al. HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases. , 1997, Journal of immunology.
[54] A. Bernard,et al. Apoptosis of immature thymocytes mediated by E2/CD99. , 1997, Journal of immunology.
[55] T. Tsuruo,et al. Phosphatidylserine externalization is a downstream event of interleukin-1 beta-converting enzyme family protease activation during apoptosis. , 1997, Blood.
[56] D. Serraino,et al. CD30 ligand is frequently expressed in human hematopoietic malignancies of myeloid and lymphoid origin. , 1997, Blood.
[57] W. Earnshaw,et al. Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis* , 1997, The Journal of Biological Chemistry.
[58] U. Francke,et al. Molecular Cloning, Mapping to Human Chromosome 1 q21-q23, and Cell Binding Characteristics of Spα, a New Member of the Scavenger Receptor Cysteine-rich (SRCR) Family of Proteins* , 1997, The Journal of Biological Chemistry.
[59] J. Cidlowski,et al. Native Recombinant Cyclophilins A, B, and C Degrade DNA Independently of Peptidylprolyl cis-trans-Isomerase Activity , 1997, The Journal of Biological Chemistry.
[60] Z. Fuks,et al. Stress-induced apoptosis and the sphingomyelin pathway. , 1997, Biochemical pharmacology.
[61] H. Kizaki,et al. Peptidyl aldehyde inhibitors of proteasome induce apoptosis rapidly in mouse lymphoma RVC cells. , 1997, Journal of biochemistry.
[62] R. Flavell,et al. Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma. , 1997, Journal of immunology.
[63] S. Fesik,et al. Identification of a novel regulatory domain in Bcl‐xL and Bcl‐2 , 1997, The EMBO journal.
[64] A. Klippel,et al. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt , 1997, Molecular and cellular biology.
[65] P. Golstein. Controlling Cell Death , 1997, Science.
[66] Dean P. Jones,et al. Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked , 1997, Science.
[67] G. Núñez,et al. Interaction and Regulation of Subcellular Localization of CED-4 by CED-9 , 1997, Science.
[68] A. Chinnaiyan,et al. Interaction of CED-4 with CED-3 and CED-9: A Molecular Framework for Cell Death , 1997, Science.
[69] D. Green,et al. The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis , 1997, Science.
[70] Lewis C Cantley,et al. PI3K: Downstream AKTion Blocks Apoptosis , 1997, Cell.
[71] M. Nehls,et al. Suppression of Apoptosis by Nitric Oxide via Inhibition of Interleukin-1β–converting Enzyme (ICE)-like and Cysteine Protease Protein (CPP)-32–like Proteases , 1997, The Journal of experimental medicine.
[72] T. Tsuruo,et al. c-Jun NH2-terminal Kinase-mediated Activation of Interleukin-1β Converting Enzyme/CED-3-like Protease during Anticancer Drug-induced Apoptosis* , 1997, The Journal of Biological Chemistry.
[73] Daniel J. Hoeppner,et al. Interaction between the C. elegans cell-death regulators CED-9 and CED-4 , 1997, Nature.
[74] P. Kiener,et al. Co-ligation of the Antigen and Fc Receptors Gives Rise to the Selective Modulation of Intracellular Signaling in B Cells , 1997, The Journal of Biological Chemistry.
[75] A. Halestrap,et al. Oxidative Stress, Thiol Reagents, and Membrane Potential Modulate the Mitochondrial Permeability Transition by Affecting Nucleotide Binding to the Adenine Nucleotide Translocase* , 1997, The Journal of Biological Chemistry.
[76] G. Evan,et al. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB , 1997, Nature.
[77] Y. Hannun,et al. Cytokine Response Modifier A (CrmA) Inhibits Ceramide Formation in Response to Tumor Necrosis Factor (TNF)-α: CrmA and Bcl-2 Target Distinct Components in the Apoptotic Pathway , 1997, The Journal of experimental medicine.
[78] J. Berzofsky,et al. Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases. , 1997, Immunity.
[79] A. Eastman,et al. Zinc inhibits apoptosis upstream of ICE/CED-3 proteases rather than at the level of an endonuclease , 1997, Cell Death and Differentiation.
[80] J. Turrens. Superoxide Production by the Mitochondrial Respiratory Chain , 1997, Bioscience reports.
[81] David R. Kaplan,et al. Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt , 1997, Science.
[82] B. Hemmings. Akt Signaling--Linking Membrane Events to Life and Death Decisions , 1997, Science.
[83] David R. Kaplan,et al. Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate , 1997, Science.
[84] G. Salvesen,et al. FLICE Induced Apoptosis in a Cell-free System , 1997, The Journal of Biological Chemistry.
[85] A. Strasser,et al. Bcl-2, Bcl-xL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death , 1997, Oncogene.
[86] P. Walker,et al. Identification of a novel 97 kDa endonuclease capable of internucleosomal DNA cleavage. , 1997, Biochemistry.
[87] T. Maniatis,et al. Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway , 1997, Cell.
[88] D. H. Burgess,et al. Involvement of cellular proteolytic machinery in apoptosis. , 1997, Biochemical and biophysical research communications.
[89] Andy J. Minn,et al. Bcl-xL forms an ion channel in synthetic lipid membranes , 1997, Nature.
[90] T. Mak,et al. Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3 , 1997, Nature.
[91] Emad S. Alnemri,et al. Activation of a CrmA-insensitive, p35-sensitive Pathway in Ionizing Radiation-induced Apoptosis* , 1997, The Journal of Biological Chemistry.
[92] B. Mayer,et al. Crk is required for apoptosis in Xenopus egg extracts , 1997, The EMBO journal.
[93] G. Evan,et al. Inhibition of Ced-3/ICE-related Proteases Does Not Prevent Cell Death Induced by Oncogenes, DNA Damage, or the Bcl-2 Homologue Bak , 1997, The Journal of cell biology.
[94] A. Eastman,et al. The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis. , 1997, Experimental cell research.
[95] G. Natoli,et al. Activation of SAPK/JNK by TNF Receptor 1 Through a Noncytotoxic TRAF2-Dependent Pathway , 1997, Science.
[96] K. Schuebel,et al. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product , 1997, Nature.
[97] E. Alnemri,et al. Resistance of actin to cleavage during apoptosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[98] Minoru Takagi,et al. Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways , 1997, Science.
[99] Vishva M. Dixit,et al. RAIDD is a new 'death' adaptor molecule , 1997, Nature.
[100] J. Ashwell,et al. Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis , 1997, Molecular and cellular biology.
[101] C. Kuo,et al. Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases , 1997, Molecular and cellular biology.
[102] D. Pot,et al. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain , 1997, Molecular and cellular biology.
[103] G. Kroemer,et al. Redox regulation of apoptosis: Impact of thiol oxidation status on mitochondrial function , 1997, European journal of immunology.
[104] E. Alnemri,et al. Baculovirus P35 inhibits the glucocorticoid-mediated pathway of cell death. , 1997, Cancer research.
[105] G. Kroemer,et al. Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. , 1997, Cancer research.
[106] P. Warne,et al. R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways , 1997, Current Biology.
[107] T. Fojo,et al. Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death. , 1997, Cancer research.
[108] T. Osborne,et al. Two Tandem Binding Sites for Sterol Regulatory Element Binding Proteins Are Required for Sterol Regulation of Fatty-acid Synthase Promoter* , 1996, The Journal of Biological Chemistry.
[109] S. Orrenius,et al. Involvement of extracellular calcium in phosphatidylserine exposure during apoptosis , 1996, FEBS letters.
[110] T. Mak,et al. Lineage-specific control of superantigen-induced cell death by the protein tyrosine kinase p56(lck). , 1996, Journal of immunology.
[111] R. Davis,et al. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. , 1996, The Journal of biological chemistry.
[112] J. Xiang,et al. BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[113] D. H. Burgess,et al. Protease Involvement in Fodrin Cleavage and Phosphatidylserine Exposure in Apoptosis* , 1996, The Journal of Biological Chemistry.
[114] E. White,et al. Lamin proteolysis facilitates nuclear events during apoptosis , 1996, The Journal of cell biology.
[115] J. Woodgett,et al. MLK‐3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6. , 1996, The EMBO journal.
[116] T. Mak,et al. Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo , 1996, European journal of immunology.
[117] G. Kroemer,et al. Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. , 1996, Cytometry.
[118] A. Strasser,et al. The cell death inhibitor Bcl‐2 and its homologues influence control of cell cycle entry. , 1996, The EMBO journal.
[119] R. Testi,et al. Sphingomyelin breakdown and cell fate. , 1996, Trends in biochemical sciences.
[120] T. Pawson,et al. HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway. , 1996, The EMBO journal.
[121] G. Kroemer,et al. Mitochondrial permeability transition triggers lymphocyte apoptosis. , 1996, Journal of immunology.
[122] P. Cohen,et al. Mechanism of activation of protein kinase B by insulin and IGF‐1. , 1996, The EMBO journal.
[123] K. Kinnally,et al. A mitochondrial signal peptide from Neurospora crassa increases the permeability of isolated rat liver mitochondria. , 1996, Archives of biochemistry and biophysics.
[124] P. Henkart,et al. Different Interleukin-1β Converting Enzyme (ICE) Family Protease Requirements for the Apoptotic Death of T Lymphocytes Triggered by Diverse Stimuli , 1996, The Journal of experimental medicine.
[125] P. Hornsby,et al. Presence of double-strand breaks with single-base 3' overhangs in cells undergoing apoptosis but not necrosis , 1996, The Journal of cell biology.
[126] J. Young,et al. CAR1, a TNFR–Related Protein, Is a Cellular Receptor for Cytopathic Avian Leukosis–Sarcoma Viruses and Mediates Apoptosis , 1996, Cell.
[127] D. Goeddel,et al. A death-domain-containing receptor that mediates apoptosis , 1996, Nature.
[128] Keisuke Kuida,et al. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice , 1996, Nature.
[129] J. Farber,et al. The Cytotoxicity of Tumor Necrosis Factor Depends on Induction of the Mitochondrial Permeability Transition* , 1996, The Journal of Biological Chemistry.
[130] A. Chinnaiyan,et al. CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases. , 1996, Oncogene.
[131] E. Robinet,et al. Human T cells require IL-2 but not G1/S transition to acquire susceptibility to Fas-mediated apoptosis. , 1996, Journal of immunology.
[132] M. Osborne,et al. The Inositol 5′-Phosphatase SHIP Binds to Immunoreceptor Signaling Motifs and Responds to High Affinity IgE Receptor Aggregation* , 1996, The Journal of Biological Chemistry.
[133] Seamus J. Martin,et al. Phosphatidylserine Externalization during CD95-induced Apoptosis of Cells and Cytoplasts Requires ICE/CED-3 Protease Activity* , 1996, The Journal of Biological Chemistry.
[134] Elizabeth Yang,et al. Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL , 1996, Cell.
[135] John Calvin Reed,et al. Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria , 1996, Cell.
[136] A. Chinnaiyan,et al. Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95 , 1996, Science.
[137] M. Colombini,et al. ATP Flux Is Controlled by a Voltage-gated Channel from the Mitochondrial Outer Membrane* , 1996, The Journal of Biological Chemistry.
[138] W. Welte,et al. Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore , 1996, FEBS letters.
[139] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[140] David Baltimore,et al. An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death , 1996, Science.
[141] Seamus J. Martin,et al. Suppression of TNF-α-Induced Apoptosis by NF-κB , 1996, Science.
[142] Z. Ao,et al. A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells. , 1996, Journal of immunology.
[143] J. Bluestone,et al. CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation. , 1996, Journal of immunology.
[144] T. Vu,et al. Increased Expression of the Insulin-like Growth Factor-II Gene in Wilms' Tumor Is Not Dependent on Loss of Genomic Imprinting or Loss of Heterozygosity* , 1996, The Journal of Biological Chemistry.
[145] Y. Adachi,et al. IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection: correlation with its ability to block culture-induced down-modulation of Bcl-2. , 1996, Journal of immunology.
[146] A. Bardelli,et al. HGF receptor associates with the anti‐apoptotic protein BAG‐1 and prevents cell death. , 1996, The EMBO journal.
[147] M. Karin,et al. The Ras-JNK pathway is involved in shear-induced gene expression , 1996, Molecular and cellular biology.
[148] J. Lemasters,et al. Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: evidence of the mitochondrial permeability transition. , 1996, Neuroscience.
[149] A. Eastman,et al. Intracellular Calcium Stores Are Not Required for Bcl-2-mediated Protection from Apoptosis* , 1996, Journal of Biological Chemistry.
[150] Michael Karin,et al. Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death , 1996, Cell.
[151] John Calvin Reed,et al. Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells , 1996, Molecular and cellular biology.
[152] N. Miyasaka,et al. Ceramide induces apoptosis via CPP32 activation , 1996, FEBS letters.
[153] David Baltimore,et al. NF-κB: Ten Years After , 1996, Cell.
[154] J. M. Adams,et al. Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival. , 1996, Oncogene.
[155] A. Hayday,et al. Raf regulates positive selection , 1996, European journal of immunology.
[156] Q. Lu,et al. Calpain inhibitors and serine protease inhibitors can produce apoptosis in HL-60 cells. , 1996, Archives of biochemistry and biophysics.
[157] P. Waring,et al. Thapsigargin induces mitochondrial dysfunction and apoptosis in the mastocytoma P815 cell line and in mouse thymocytes. , 1996, Cell death and differentiation.
[158] E. Solary,et al. Pivotal role of a DEVD‐sensitive step in etoposide‐induced and Fas‐mediated apoptotic pathways. , 1996, The EMBO journal.
[159] A. F. Schinder,et al. Mitochondrial Dysfunction Is a Primary Event in Glutamate Neurotoxicity , 1996, The Journal of Neuroscience.
[160] G. Kroemer,et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease , 1996, The Journal of experimental medicine.
[161] P. Tempst,et al. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FeγRIIB , 1996, Nature.
[162] S. Orrenius,et al. Chromatin condensation during apoptosis requires ATP. , 1996, The Biochemical journal.
[163] G. Krystal,et al. Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP. , 1996, Journal of immunology.
[164] I. Reynolds,et al. Mitochondrial Depolarization in Glutamate-Stimulated Neurons: An Early Signal Specific to Excitotoxin Exposure , 1996, The Journal of Neuroscience.
[165] D. McConkey. Calcium-dependent, Interleukin 1β-converting Enzyme Inhibitor-insensitive Degradation of Lamin B1 and DNA Fragmentation in Isolated Thymocyte Nuclei* , 1996, The Journal of Biological Chemistry.
[166] C. Marshall. Raf gets it together , 1996, Nature.
[167] G. Linette,et al. Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[168] E. Wang,et al. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[169] L. Samelson,et al. Complex complexes: signaling at the TCR. , 1996, Immunity.
[170] P. Anversa,et al. Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. , 1996, Journal of molecular and cellular cardiology.
[171] S. Pittman,et al. Endo-exonuclease of human leukaemic cells: evidence for a role in apoptosis. , 1996, Journal of cell science.
[172] G. Kroemer,et al. Mitochondrial permeability transition is a central coordinating event of apoptosis , 1996, The Journal of experimental medicine.
[173] M. Collins,et al. An apoptotic endonuclease activated either by decreasing pH or by increasing calcium. , 1996, Journal of cell science.
[174] R. Gottlieb,et al. Loss of Function of Cytochrome c in Jurkat Cells Undergoing Fas-mediated Apoptosis* , 1996, The Journal of Biological Chemistry.
[175] T. Whiteside,et al. Activation of Raf by ionizing radiation , 1996, Nature.
[176] D. Goeddel,et al. Anatomy of TRAF2 , 1996, The Journal of Biological Chemistry.
[177] S. Lev,et al. Activation of Pyk2 by Stress Signals and Coupling with JNK Signaling Pathway , 1996, Science.
[178] D. Goeddel,et al. I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[179] C. Smith,et al. CD30 ligand expression in nonmalignant and Hodgkin's disease-involved lymphoid tissues. , 1996, The American journal of pathology.
[180] D. Andrews,et al. Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. , 1996, The EMBO journal.
[181] Y. Pommier,et al. DNA fragmentation induced by protease activation in p53-null human leukemia HL60 cells undergoing apoptosis following treatment with the topoisomerase I inhibitor camptothecin: cell-free system studies. , 1996, Experimental cell research.
[182] H. Lei,et al. Activation of the Na(+)/H(+) antiporter, Na+/HCO3(-)/CO3(2-) cotransporter, or Cl(-)/HCO3(-) exchanger in spontaneous thymocyte apoptosis. , 1996, Journal of immunology.
[183] S. Snyder,et al. Lymphocyte Apoptosis: Mediation by Increased Type 3 Inositol 1,4,5-Trisphosphate Receptor , 1996, Science.
[184] M. Owen,et al. The MAP Kinase Pathway Controls Differentiation from Double-Negative to Double-Positive Thymocyte , 1996, Cell.
[185] Seamus J. Martin,et al. Acid Sphingomyelinase–Deficient Human Lymphoblasts and Mice Are Defective in Radiation-Induced Apoptosis , 1996, Cell.
[186] H. Matsuzaki,et al. Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[187] P. Sims,et al. Isolation of an Erythrocyte Membrane Protein that Mediates Ca2+-dependent Transbilayer Movement of Phospholipid* , 1996, The Journal of Biological Chemistry.
[188] P. Bernardi. The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. , 1996, Biochimica et biophysica acta.
[189] G. Kroemer,et al. Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. , 1996, Journal of immunology.
[190] K. Shinohara,et al. Apoptosis induction resulting from proteasome inhibition. , 1996, The Biochemical journal.
[191] S. Korsmeyer,et al. Molecular thanatopsis: a discourse on the BCL2 family and cell death. , 1996, Blood.
[192] Xiaodong Wang,et al. Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c , 1996, Cell.
[193] John Calvin Reed,et al. Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[194] Seamus J. Martin,et al. Events in Apoptosis , 1996, The Journal of Biological Chemistry.
[195] Y. Tsujimoto,et al. Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors. , 1996, Oncogene.
[196] M. Klingenberg,et al. Mitochondrial ADP/ATP carrier can be reversibly converted into a large channel by Ca2+. , 1996, Biochemistry.
[197] H. Mcdevitt,et al. The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. , 1996, Immunity.
[198] A. Chinnaiyan,et al. Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3 , 1996, Current Biology.
[199] S. Grimm,et al. Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis , 1996, The Journal of cell biology.
[200] R. Perlmutter,et al. Positive and negative selection invoke distinct signaling pathways , 1996, The Journal of experimental medicine.
[201] S. Orrenius,et al. Rapid and Specific Efflux of Reduced Glutathione during Apoptosis Induced by Anti-Fas/APO-1 Antibody* , 1996, The Journal of Biological Chemistry.
[202] S. Spiegel,et al. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate , 1996, Nature.
[203] D. Goeddel,et al. The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[204] C. Franceschi,et al. Mitochondria are selective targets for the protective effects of heat shock against oxidative injury. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[205] P. Williamson,et al. Reconstitution of phospholipid scramblase activity from human blood platelets. , 1996, Biochemistry.
[206] D. Adam,et al. A Novel Cytoplasmic Domain of the p55 Tumor Necrosis Factor Receptor Initiates the Neutral Sphingomyelinase Pathway* , 1996, The Journal of Biological Chemistry.
[207] G. Evan,et al. A License to Kill , 1996, Cell.
[208] David Wallach,et al. Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death , 1996, Cell.
[209] Matthias Mann,et al. FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex , 1996, Cell.
[210] S. Laulederkind,et al. Ceramide signalling and the immune response. , 1996, Biochimica et biophysica acta.
[211] A. Marks,et al. Regulation of the Inositol 1,4,5-Trisphosphate Receptor by Tyrosine Phosphorylation , 1996, Science.
[212] R. Schlegel,et al. A Subfamily of P-Type ATPases with Aminophospholipid Transporting Activity , 1996, Science.
[213] M. Andreeff,et al. CD30 ligand is expressed on resting normal and malignant human B lymphocytes , 1996, British journal of haematology.
[214] T. Gotoh,et al. Death of germinal center B cells without DNA fragmentation , 1996, European journal of immunology.
[215] M. Karin,et al. Mitogen-activated protein kinase cascades and regulation of gene expression. , 1996, Current opinion in immunology.
[216] M. Raff,et al. Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death , 1996, The Journal of cell biology.
[217] M. Raff,et al. Constitutive expression of the machinery for programmed cell death , 1996, The Journal of cell biology.
[218] M. Greenberg,et al. E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation , 1996, Cell.
[219] Y. Tsujimoto,et al. Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions. , 1996, Oncogene.
[220] F. Alt,et al. Activated Ras signals differentiation and expansion of CD4+8+ thymocytes. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[221] L. Rohrschneider,et al. p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity. , 1996, Genes & development.
[222] J. Hsuan,et al. Involvement of cyclophilin D in the activation of a mitochondrial pore by Ca2+ and oxidant stress. , 1996, European journal of biochemistry.
[223] B. Osborne,et al. The role of oxygen in thymocyte apoptosis , 1996, European journal of immunology.
[224] I. Macara,et al. JNK, but not MAPK, activation is associated with Fas‐mediated apoptosis in human T cells , 1996, European journal of immunology.
[225] A. Chinnaiyan,et al. The cell-death machine , 1996, Current Biology.
[226] L. Zon,et al. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat , 1996, Current Biology.
[227] H. Petrie,et al. Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death , 1996, The Journal of experimental medicine.
[228] G. Kroemer,et al. Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. , 1996, Cancer research.
[229] S. Nagata,et al. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis , 1996, Nature.
[230] L. Neckers,et al. Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. , 1996, Cancer research.
[231] G. Kroemer,et al. Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis , 1996, FEBS letters.
[232] D. Goeddel,et al. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. , 1996, Immunity.
[233] D. Griffin,et al. Temporal changes in chromatin, intracellular calcium, and poly(ADP-ribose) polymerase during Sindbis virus-induced apoptosis of neuroblastoma cells , 1996, Journal of virology.
[234] S. Spiegel,et al. Signal transduction through lipid second messengers. , 1996, Current opinion in cell biology.
[235] C. Mannella,et al. Perspectives on the mitochondrial multiple conductance channel , 1996, Journal of bioenergetics and biomembranes.
[236] R. Treisman,et al. Regulation of transcription by MAP kinase cascades. , 1996, Current opinion in cell biology.
[237] Paolo Bernardi,et al. The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal , 1996, Journal of bioenergetics and biomembranes.
[238] G. Cohen,et al. Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. , 1996, The Biochemical journal.
[239] D. Alexander,et al. CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation , 1996, The Journal of experimental medicine.
[240] Pingar Yang,et al. Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self- reactive T cells , 1996, The Journal of experimental medicine.
[241] G. Kroemer,et al. Mitochondrial control of nuclear apoptosis , 1996, The Journal of experimental medicine.
[242] B. Chernyak,et al. Modulation of the Mitochondrial Permeability Transition Pore by Pyridine Nucleotides and Dithiol Oxidation at Two Separate Sites (*) , 1996, The Journal of Biological Chemistry.
[243] Z. Darżynkiewicz,et al. Effect of protease inhibitors on early events of apoptosis. , 1996, Experimental cell research.
[244] F. Herrmann,et al. Activation of Hodgkin cells via the CD30 receptor induces autocrine secretion of interleukin-6 engaging the NF-kappabeta transcription factor. , 1996, Blood.
[245] C. Croce,et al. Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. , 1996, Cancer research.
[246] L. Zon,et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis , 1996, Nature.
[247] G. Salvesen,et al. Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[248] D. Bredesen,et al. Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[249] N. Williams. Immunology: T Cell Inactivation Linked to Ras Block , 1996, Science.
[250] A. Mondino,et al. Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells , 1996, Science.
[251] D. Wallach,et al. A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other , 1996, The Journal of experimental medicine.
[252] Philip R. Cohen,et al. Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells. , 1996, European journal of biochemistry.
[253] A. Chinnaiyan,et al. FADD/MORT1 Is a Common Mediator of CD95 (Fas/APO-1) and Tumor Necrosis Factor Receptor-induced Apoptosis (*) , 1996, The Journal of Biological Chemistry.
[254] A. Berns,et al. T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage‐induced cell death in the absence of p53. , 1996, The EMBO journal.
[255] P. Fields,et al. Blocked Ras Activation in Anergic CD4+ T Cells , 1996, Science.
[256] R. Davis,et al. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway , 1996, Molecular and cellular biology.
[257] P. Henkart. ICE family proteases: mediators of all apoptotic cell death? , 1996, Immunity.
[258] H. Boehmer. CD4/CD8 lineage commitment: back to instruction? , 1996 .
[259] H. Griesser,et al. Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice , 1996, Cell.
[260] M. Petri,et al. Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[261] G. Cohen,et al. A cleavage-site-directed inhibitor of interleukin-1 beta-converting enzyme-like proteases inhibits apoptosis in primary cultures of rat hepatocytes. , 1996, The Biochemical journal.
[262] L. Zon,et al. Signal Transduction Pathways Regulated by Mitogen-activated/Extracellular Response Kinase Kinase Kinase Induce Cell Death (*) , 1996, The Journal of Biological Chemistry.
[263] K. Vousden,et al. p53 in signaling checkpoint arrest or apoptosis. , 1996, Current opinion in genetics & development.
[264] C. Faucheu,et al. Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme. , 1996, European journal of biochemistry.
[265] G. Koretzky,et al. Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. , 1996, Blood.
[266] P. Bernardi,et al. Interactions of Cyclophilin with the Mitochondrial Inner Membrane and Regulation of the Permeability Transition Pore, a Cyclosporin A-sensitive Channel (*) , 1996, The Journal of Biological Chemistry.
[267] Hong-Bing Shu,et al. TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways , 1996, Cell.
[268] K. Tamai,et al. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes , 1996, Nature.
[269] R. Gottlieb,et al. Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[270] A. Chinnaiyan,et al. ICE-LAP3, a Novel Mammalian Homologue of the Caenorhabditis elegans Cell Death Protein Ced-3 Is Activated during Fas- and Tumor Necrosis Factor-induced Apoptosis (*) , 1996, The Journal of Biological Chemistry.
[271] E. Podack,et al. Structure and expression of murine CD30 and its role in cytokine production. , 1996, Journal of immunology.
[272] G. Kroemer,et al. Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential. , 1996, Journal of immunology.
[273] T. Tan,et al. Persistent Activation of c-Jun N-terminal Kinase 1 (JNK1) in γ Radiation-induced Apoptosis (*) , 1996, The Journal of Biological Chemistry.
[274] M. Melamed,et al. Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color. , 1996, Experimental cell research.
[275] J. Woodgett,et al. Cross‐linking CD40 on B cells preferentially induces stress‐activated protein kinases rather than mitogen‐activated protein kinases. , 1996, The EMBO journal.
[276] M. Lavin,et al. The ICE family of cysteine proteases as effectors of cell death. , 1996, Cell death and differentiation.
[277] S. Orrenius,et al. Intracellular redox changes during apoptosis. , 1996, Cell death and differentiation.
[278] J. Woodgett,et al. The stress activated protein kinase pathway. , 1996, Cancer surveys.
[279] F. Herrmann,et al. Structural and biological features of the TNF receptor and TNF ligand superfamilies: interactive signals in the pathobiology of Hodgkin's disease. , 1996, Annals of oncology : official journal of the European Society for Medical Oncology.
[280] Mike Rothe,et al. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins , 1995, Cell.
[281] L. Baum,et al. Apoptosis of T cells mediated by galectin-1 , 1995, Nature.
[282] F. McCormick. Ras‐related proteins in signal transduction and growth control , 1995, Molecular reproduction and development.
[283] G. Kroemer,et al. Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo , 1995, European journal of immunology.
[284] A. Strasser,et al. Bcl‐2 and Fas/APO‐1 regulate distinct pathways to lymphocyte apoptosis. , 1995, The EMBO journal.
[285] B. Dérijard,et al. Cdc42 and PAK-mediated Signaling Leads to Jun Kinase and p38 Mitogen-activated Protein Kinase Activation (*) , 1995, The Journal of Biological Chemistry.
[286] Michael E. Greenberg,et al. Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis , 1995, Science.
[287] M. Moreno,et al. Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in a T cell hybridoma. , 1995, Journal of immunology.
[288] L. Ghibelli,et al. Non-oxidative loss of glutathione in apoptosis via GSH extrusion. , 1995, Biochemical and biophysical research communications.
[289] M. Peter,et al. Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor. , 1995, The EMBO journal.
[290] S. Nagata,et al. Apoptosis by a cytosolic extract from Fas‐activated cells. , 1995, The EMBO journal.
[291] D. Green,et al. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl , 1995, The Journal of experimental medicine.
[292] J. Weidner,et al. The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy , 1995, The Journal of experimental medicine.
[293] P. Williamson,et al. Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes , 1995, The Journal of experimental medicine.
[294] G. Cohen,et al. An ICE‐like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells , 1995, FEBS letters.
[295] B. Chapman. A region of the 75 kDa neurotrophin receptor homologous to the death domains of TNFR‐I and Fas , 1995, FEBS letters.
[296] D. Faller,et al. Direction of p21ras-generated signals towards cell growth or apoptosis is determined by protein kinase C and Bcl-2. , 1995, Oncogene.
[297] S. Korsmeyer,et al. Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death , 1995, Science.
[298] Guido Kroemer,et al. The biochemistry of programmed cell death , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[299] G. Pizzolo,et al. CD30 ligation induces nuclear factor‐ϰB activation in human T cell lines , 1995, European journal of immunology.
[300] J. Torres-Roca,et al. The early intracellular production of a reactive oxygen intermediate mediates apoptosis in dexamethasone-treated thymocytes. , 1995, Cell death and differentiation.
[301] R. Willemze,et al. CD30 expression in normal and neoplastic lymphoid tissue: biological aspects and clinical implications. , 1995, Leukemia.
[302] G. Kroemer,et al. Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers. , 1995, Blood.
[303] D. Brenner,et al. Ceramide Activates the Stress-activated Protein Kinases (*) , 1995, The Journal of Biological Chemistry.
[304] J. Mankovich,et al. Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. , 1995, Science.
[305] M. Lenardo,et al. Induction of apoptosis in mature T cells by tumour necrosis factor , 1995, Nature.
[306] Y. Lazebnik,et al. Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[307] M. Hallek,et al. CD30 ligand signal transduction involves activation of a tyrosine kinase and of mitogen-activated protein kinase in a Hodgkin's lymphoma cell line. , 1995, Cancer research.
[308] D. Goeddel,et al. TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 , 1995, Science.
[309] P. Waring,et al. A decrease in intracellular glutathione concentration precedes the onset of apoptosis in murine thymocytes. , 1995, European journal of cell biology.
[310] I. Kuntz,et al. Modeled structure of the 75‐kDa neurotrophin receptor , 1995, Protein science : a publication of the Protein Society.
[311] A. Ashworth,et al. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1 , 1995, Science.
[312] C. Franceschi,et al. Protective effect of N-acetylcysteine in tumor necrosis factor-alpha-induced apoptosis in U937 cells: the role of mitochondria. , 1995, Experimental cell research.
[313] B. Burgering,et al. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction , 1995, Nature.
[314] Z. Oltvai,et al. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[315] Seamus J. Martin,et al. Protease activation during apoptosis: Death by a thousand cuts? , 1995, Cell.
[316] L. Heasley,et al. Activation of Jun Kinase/Stress-activated Protein Kinase by GTPase-deficient Mutants of Gα12 and Gα13(*) , 1995, The Journal of Biological Chemistry.
[317] K. Nakayama,et al. Essential role for ZAP-70 in both positive and negative selection of thymocytes , 1995, Nature.
[318] C. Maliszewski,et al. Regulation of murine B cell growth and differentiation by CD30 ligand , 1995, European journal of immunology.
[319] G. Kroemer,et al. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death , 1995, The Journal of experimental medicine.
[320] M. Zoratti,et al. The mitochondrial permeability transition. , 1995, Biochimica et biophysica acta.
[321] M. Krönke,et al. TNF-induced activation of NF-kappa B. , 1995, Immunobiology.
[322] C. Thompson,et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. , 1995, Immunity.
[323] T. Mak,et al. T cell repertoire and clonal deletion of Mtv superantigen‐reactive T cells in mice lacking CD4 and CD8 molecules , 1995, European journal of immunology.
[324] P. Petit,et al. Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis , 1995, The Journal of cell biology.
[325] P. Crespo,et al. The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway , 1995, Cell.
[326] L. Genestier,et al. Apoptosis without decrease of cell DNA content , 1995, FEBS letters.
[327] E. Goldsmith,et al. How MAP Kinases Are Regulated (*) , 1995, The Journal of Biological Chemistry.
[328] H. Kawasaki,et al. Evidence for Multiple Activators for Stress-activated Protein Kinases/c-Jun Amino-terminal Kinases. , 1995, The Journal of Biological Chemistry.
[329] H. Ikeda,et al. DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis. , 1995, The American journal of pathology.
[330] K. Wang,et al. Aurintricarboxylic acid is an inhibitor of mu- and m-calpain. , 1995, Biochemistry and molecular biology international.
[331] T. Mak,et al. CD28 signals through acidic sphingomyelinase , 1995, The Journal of experimental medicine.
[332] Z. Fuks,et al. Ceramide: a signal for apoptosis or mitogenesis? , 1995, The Journal of experimental medicine.
[333] W. Neupert,et al. Translocation of Apocytochrome c across the Outer Membrane of Mitochondria (*) , 1995, The Journal of Biological Chemistry.
[334] Arul M. Chinnaiyan,et al. FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis , 1995, Cell.
[335] D. Goeddel,et al. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation , 1995, Cell.
[336] C. Croce,et al. Inactivation of Bcl-2 by phosphorylation. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[337] P. Bernardi,et al. On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide. , 1995, Toxicology.
[338] S. Nagata,et al. Involvement of an ICE-like protease in Fas-mediated apoptosis , 1995, Nature.
[339] W. Fiers,et al. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis , 1995, Nature.
[340] M. Su,et al. A novel human protease similar to the interleukin‐1 beta converting enzyme induces apoptosis in transfected cells. , 1995, The EMBO journal.
[341] G. Kroemer,et al. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo , 1995, The Journal of experimental medicine.
[342] P. Golstein,et al. The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity , 1995, The Journal of experimental medicine.
[343] M. Raff,et al. Programmed cell death and Bcl-2 protection in very low oxygen , 1995, Nature.
[344] Y. Tsujimoto,et al. Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL , 1995, Nature.
[345] John Calvin Reed,et al. FAP-1: a protein tyrosine phosphatase that associates with Fas. , 1995, Science.
[346] M. Karin,et al. Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. , 1995, Science.
[347] B. Herman,et al. Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. , 1995, The Biochemical journal.
[348] M. Su,et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. , 1995, Science.
[349] Jiahuai Han,et al. Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine (*) , 1995, The Journal of Biological Chemistry.
[350] M. Barbacid,et al. Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes , 1995, Nature.
[351] al. et,et al. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice , 1995, Science.
[352] C. Thompson,et al. Apoptosis in the pathogenesis and treatment of disease , 1995, Science.
[353] S. Nagata,et al. The Fas death factor , 1995, Science.
[354] S. Novgorodov,et al. The Peptide Mastoparan Is a Potent Facilitator of the Mitochondrial Permeability Transition (*) , 1995, The Journal of Biological Chemistry.
[355] M. Fukuda,et al. Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells , 1995, The Journal of experimental medicine.
[356] D. Thorley-Lawson,et al. A novel form of Epstein-Barr virus latency in normal B cells in vivo , 1995, Cell.
[357] E. Krebs,et al. Selective requirement for MAP kinase activation in thymocyte differentiation , 1995, Nature.
[358] R. Kamen,et al. Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock , 1995, Cell.
[359] P. Krammer,et al. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) , 1995, Nature.
[360] D. Bredesen,et al. Expression of bcl‐2 inhibits necrotic neural cell death , 1995, Journal of neuroscience research.
[361] B. Trump,et al. Calcium‐mediated cell injury and cell death , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[362] S. Nagata,et al. Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody , 1995, The Journal of experimental medicine.
[363] John Calvin Reed,et al. Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity , 1995, Cell.
[364] P. O'dwyer,et al. Apoptosis in human adenocarcinoma HT29 cells induced by exposure to hypoxia. , 1995, Journal of the National Cancer Institute.
[365] Mariana Gerschenson,et al. Endonuclease G from mammalian nuclei is identical to the major endonuclease of mitochondria , 1995, Nucleic Acids Res..
[366] G. Cohen,et al. A pre‐existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli , 1995, FEBS letters.
[367] R. Perlmutter,et al. Involvement of p21ras distinguishes positive and negative selection in thymocytes. , 1995, The EMBO journal.
[368] John Calvin Reed,et al. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene , 1995, Cell.
[369] S. Cory. Regulation of lymphocyte survival by the bcl-2 gene family. , 1995, Annual review of immunology.
[370] G. Pizzolo,et al. CD30, Th2 cytokines and HIV infection: a complex and fascinating link. , 1995, Immunology today.
[371] R. Mikkelsen,et al. Induction of apoptotic DNA fragmentation and c-jun downregulation in human myeloid leukemia cells by the permeant Ca2+ chelator BAPTA/AM. , 1995, Oncology research.
[372] G. Kroemer. The pharmacology of T cell apoptosis. , 1995, Advances in immunology.
[373] H. von Boehmer,et al. Development and selection of T cells: facts and puzzles. , 1995, Advances in immunology.
[374] S. Nagata,et al. Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver , 1995, Nature Genetics.
[375] L. Zon,et al. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 , 1994, Nature.
[376] L. Zon,et al. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun , 1994, Nature.
[377] I. Tsigelny,et al. JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. , 1994, Genes & development.
[378] G L Johnson,et al. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. , 1994, Science.
[379] J. Hoek,et al. Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone. , 1994, The Journal of biological chemistry.
[380] D. Goeddel,et al. Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice , 1994, Nature.
[381] M. Boguski,et al. A novel RING finger protein interacts with the cytoplasmic domain of CD40. , 1994, The Journal of biological chemistry.
[382] T. Mak,et al. Signal Transduction, Mitotic Catastrophes, and Death in T‐Cell Development , 1994, Immunological reviews.
[383] L. Schwartz,et al. Identification of Genes Induced during Apoptosis in T Lymphocytes , 1994, Immunological reviews.
[384] H. Drexler,et al. Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines. , 1994, Leukemia.
[385] D. Green,et al. Promotion and Inhibition of Activation‐Induced Apoptosis in T‐Cell Hybridomas by Oncogenes and Related Signals , 1994, Immunological reviews.
[386] M. Peter,et al. The Role of APO‐1‐Mediated Apoptosis in the Immune System , 1994, Immunological reviews.
[387] P Waring,et al. Lack of correlation between early intracellular calcium ion rises and the onset of apoptosis in thymocytes , 1994, Immunology and cell biology.
[388] P. Petit,et al. Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[389] D. Fruman,et al. Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. , 1994, Transplantation.
[390] J. Sprent,et al. T-cell apoptosis detected in situ during positive and negative selection in the thymus , 1994, Nature.
[391] M. Chao. The p75 neurotrophin receptor. , 1994, Journal of neurobiology.
[392] A. Haimovitz-Friedman,et al. The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation. , 1994, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[393] C. Croce,et al. Antiapoptosis potential of bcl-2 oncogene by dephosphorylation. , 1994, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[394] D. Newmeyer,et al. Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria , 1994, Cell.
[395] Z. Oltvai,et al. Checkpoints of dueling dimers foil death wishes , 1994, Cell.
[396] J. Woodgett,et al. The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion. , 1994, The Journal of biological chemistry.
[397] D. Hirschstein,et al. Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for Hodgkin's disease , 1994 .
[398] K. Schulze-Osthoff,et al. Divergent signalling via APO‐1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death. , 1994, The EMBO journal.
[399] Jean-Claude Martinou,et al. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia , 1994, Neuron.
[400] M. Karin,et al. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases , 1994, Molecular and cellular biology.
[401] K. Schulze-Osthoff,et al. Cell nucleus and DNA fragmentation are not required for apoptosis , 1994, The Journal of cell biology.
[402] M. Krönke,et al. Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling , 1994, Cell.
[403] Y. Lazebnik,et al. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE , 1994, Nature.
[404] L. Samelson,et al. The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor. , 1994, The Journal of biological chemistry.
[405] S. Nagata,et al. No requirement of reactive oxygen intermediates in Fas‐mediated apoptosis , 1994, FEBS letters.
[406] S. Krajewski,et al. Apoptosis regulation by interaction of Bcl-2 protein and Raf-1 kinase. , 1994, Oncogene.
[407] G. Sutherland,et al. Moslecular and biological characterization of human 4‐1BB and its ligands , 1994, European journal of immunology.
[408] C. Reutelingsperger,et al. Expression on B Cells Undergoing Apoptosis Annexin V for Flow Cytometric Detection of Phosphatidylserine , 2022 .
[409] D. Goeddel,et al. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor , 1994, Cell.
[410] L Bibbs,et al. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. , 1994, Science.
[411] A. Haimovitz-Friedman,et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis , 1994, The Journal of experimental medicine.
[412] A. Abbas,et al. The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. , 1994, Immunity.
[413] S. Yonehara,et al. Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target , 1994, The Journal of experimental medicine.
[414] I. Stamenkovic,et al. Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions , 1994, The Journal of experimental medicine.
[415] J. Cidlowski,et al. A calcium-dependent nuclease from apoptotic rat thymocytes is homologous with cyclophilin. Recombinant cyclophilins A, B, and C have nuclease activity. , 1994, The Journal of biological chemistry.
[416] H Hengartner,et al. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. , 1994, Science.
[417] J. Strominger,et al. Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[418] H. Teh,et al. Activation-induced cell death in proliferating T cells is associated with altered tyrosine phosphorylation of TCR/CD3 subunits. , 1994, Journal of immunology.
[419] X. M. Sun,et al. Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes. , 1994, Journal of immunology.
[420] N. Copeland,et al. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. , 1994, Genes & development.
[421] R. V. van Lier,et al. CD27: marker and mediator of T-cell activation? , 1994, Immunology today.
[422] Z. Oltvai,et al. Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus. , 1994, The Journal of biological chemistry.
[423] C. Marshall,et al. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells , 1994, Cell.
[424] John Calvin Reed,et al. Identification of a p53-dependent negative response element in the bcl-2 gene. , 1994, Cancer research.
[425] Masahiko Hibi,et al. JNK is involved in signal integration during costimulation of T lymphocytes , 1994, Cell.
[426] D. Green,et al. Activation-induced apoptosis in lymphocytes. , 1994, Current opinion in immunology.
[427] John Calvin Reed,et al. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. , 1994, Oncogene.
[428] John Calvin Reed,et al. Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways. , 1994, Oncogene.
[429] R. Armitage. Tumor necrosis factor receptor superfamily members and their ligands. , 1994, Current opinion in immunology.
[430] H. Kitayama,et al. Induction of programmed cell death in human hematopoietic cell lines by fibronectin via its interaction with very late antigen 5 , 1994, The Journal of experimental medicine.
[431] M. Ticchioni,et al. Engagement of the CD45 molecule induces homotypic adhesion of human thymocytes through a LFA-1/ICAM-3-dependent pathway. , 1994, Journal of immunology.
[432] M. Murphy,et al. Peroxynitrite causes calcium efflux from mitochondria which is prevented by Cyclosporin A , 1994, FEBS letters.
[433] John Calvin Reed,et al. Anchorage dependence, integrins, and apoptosis , 1994, Cell.
[434] P. Baeuerle,et al. Sphingomyelinase activates proteolytic I kappa B-alpha degradation in a cell-free system. , 1994, The Journal of biological chemistry.
[435] J. Woodgett,et al. The stress-activated protein kinase subfamily of c-Jun kinases , 1994, Nature.
[436] A. Tordai,et al. Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes. , 1994, The Journal of clinical investigation.
[437] J. Coligan,et al. Constitutive activation of integrin alpha 4 beta 1 defines a unique stage of human thymocyte development , 1994, The Journal of experimental medicine.
[438] B. Stewart,et al. Inhibition of topoisomerase II by aurintricarboxylic acid: implications for mechanisms of apoptosis. , 1994, Anticancer research.
[439] Scott F. Smith,et al. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. , 1994, Science.
[440] B. Beutler,et al. Unraveling function in the TNF ligand and receptor families. , 1994, Science.
[441] C. Ware,et al. A lymphotoxin-beta-specific receptor. , 1994, Science.
[442] J. Marth,et al. Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection. , 1994, Journal of immunology.
[443] N. Viner,et al. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis , 1994, European journal of immunology.
[444] A. Ashworth,et al. Identification of the sites in MAP kinase kinase‐1 phosphorylated by p74raf‐1. , 1994, The EMBO journal.
[445] S. Hedrick,et al. Intracellular signals that mediate thymic negative selection. , 1994, Immunity.
[446] M. Raff,et al. Programmed cell death and Bcl‐2 protection in the absence of a nucleus. , 1994, The EMBO journal.
[447] Terry Farrah,et al. The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death , 1994, Cell.
[448] M. Karin,et al. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain , 1994, Cell.
[449] D. Pardoll,et al. Cyclosporin A inhibits positive selection and delays negative selection in alpha beta TCR transgenic mice. , 1994, Journal of immunology.
[450] T. Owens,et al. Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis. , 1994, International immunology.
[451] P. Krammer,et al. Differential expression of APO‐1 on human thymocytes: Implications for negative selection? , 1994, European journal of immunology.
[452] J. Marth,et al. Specific CD45 isoforms differentially regulate T cell receptor signaling. , 1994, The EMBO journal.
[453] M. Peitsch,et al. The apoptosis endonucleases: cleaning up after cell death? , 1994, Trends in cell biology.
[454] B. Hoffmann,et al. The reconstituted ADP/ATP carrier activity has an absolute requirement for cardiolipin as shown in cysteine mutants. , 1994, The Journal of biological chemistry.
[455] L. Schwartz,et al. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate–early gene nur77 , 1994, Nature.
[456] John Calvin Reed. Bcl-2 and the regulation of programmed cell death , 1994, The Journal of cell biology.
[457] E. Lacy,et al. The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult αβ thymocytes , 1994 .
[458] T. Mak,et al. Lymphocyte ontogeny and activation in gene targeted mutant mice. , 1994, Annual review of immunology.
[459] I. Trowbridge,et al. CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. , 1994, Annual review of immunology.
[460] Takashi Suda,et al. Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family , 1993, Cell.
[461] M. Lotz,et al. A receptor induced by lymphocyte activation (ILA): a new member of the human nerve-growth-factor/tumor-necrosis-factor receptor family. , 1993, Gene.
[462] F. Ramsdell,et al. Fas transduces activation signals in normal human T lymphocytes , 1993, The Journal of experimental medicine.
[463] D. Bredesen,et al. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. , 1993, Science.
[464] Junying Yuan,et al. Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3 , 1993, Cell.
[465] J. Bischoff,et al. Bcl-2 associates with the ras-related protein R-rasp23 , 1993, Nature.
[466] P. Linsley,et al. Identification of an alternative CTLA-4 ligand costimulatory for T cell activation. , 1993, Science.
[467] M. Salmon,et al. A possible role for bcl-2 in regulating T-cell memory--a 'balancing act' between cell death and survival. , 1993, Immunology today.
[468] S. Korsmeyer,et al. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair , 1993, Cell.
[469] Z. Oltvai,et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis , 1993, Cell.
[470] O. Stutman,et al. Immune functions of tumor necrosis factor. I. Tumor necrosis factor induces apoptosis of mouse thymocytes and can also stimulate or inhibit IL-6-induced proliferation depending on the concentration of mitogenic costimulation. , 1993, Journal of immunology.
[471] T. Mak,et al. The Role of p56ICk and p59fyn Tyrosine Kinases and CD45 Protein Tyrosine Phosphatase in T‐cell Development and Clonal Selection , 1993, Immunological reviews.
[472] M. Berridge. A tale of two messengers , 1993, Nature.
[473] V. Stewart,et al. Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. , 1993, Science.
[474] L. Tartaglia,et al. A novel domain within the 55 kd TNF receptor signals cell death , 1993, Cell.
[475] T. Wilson,et al. The thymic microenvironment. , 1993, Immunology today.
[476] T. Mak,et al. Normal B lymphocyte development but impaired T cell maturation in CD45-Exon6 protein tyrosine phosphatase-deficient mice , 1993, Cell.
[477] R. Kolesnick,et al. Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells. , 1993, The Journal of biological chemistry.
[478] J. Farber,et al. Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition. , 1993, The Journal of biological chemistry.
[479] C. Tepper,et al. Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death , 1993, Journal of cellular biochemistry.
[480] M. Lenardo,et al. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle , 1993, European journal of immunology.
[481] J. Ashwell,et al. Signaling for death of lymphoid cells. , 1993, Current opinion in immunology.
[482] P. Krammer,et al. Activation interferes with the APO-1 pathway in mature human T cells. , 1993, International immunology.
[483] P. Williamson,et al. Altered lipid packing identifies apoptotic thymocytes. , 1993, Immunology letters.
[484] T. Tedder,et al. Regulation of the tyrosine kinase-dependent adhesion pathway in human lymphocytes through CD45. , 1993, Journal of immunology.
[485] John Calvin Reed,et al. Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival. , 1993, The Journal of biological chemistry.
[486] T. Mak,et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection , 1993, Cell.
[487] P. Bedossa,et al. Role of CD4+CD45RA+ T cells in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse. , 1993, International immunology.
[488] G. Kroemer,et al. Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo , 1993, The Journal of experimental medicine.
[489] C. Purdie,et al. Thymocyte apoptosis induced by p53-dependent and independent pathways , 1993, Nature.
[490] Scott W. Lowe,et al. p53 is required for radiation-induced apoptosis in mouse thymocytes , 1993, Nature.
[491] C. June,et al. Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains. , 1993, Science.
[492] G. Koretzky,et al. Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45. , 1993, Science.
[493] S. Martin,et al. Protein or RNA synthesis inhibition induces apoptosis of mature human CD4+ T cell blasts. , 1993, Immunology letters.
[494] John Calvin Reed,et al. Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA , 1993, Nature.
[495] J. Tschopp,et al. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). , 1993, The EMBO journal.
[496] P. Golstein,et al. Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity , 1993, The Journal of experimental medicine.
[497] C. Haslett,et al. Phagocyte recognition of cells undergoing apoptosis. , 1993, Immunology today.
[498] G. Kroemer,et al. Compartmentalization of the peripheral immune system. , 1993, Advances in immunology.
[499] R. Schwartz. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy , 1992, Cell.
[500] T. Mak,et al. CD45RA and CD45RBhigh expression induced by thymic selection events , 1992, The Journal of experimental medicine.
[501] M. Krönke,et al. TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown , 1992, Cell.
[502] Arthur Weiss,et al. ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain , 1992, Cell.
[503] T. Mak,et al. Materials and Methods Briefdefinitive Report Cd4 Expression Is Differentially Required for Deletion of Mls-la-reactive T Cells , 2022 .
[504] C. Crews,et al. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. , 1992, Science.
[505] N. Haigwood,et al. Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis , 1992, The Journal of experimental medicine.
[506] M. Luqman,et al. Activation requirements for CD4+ T cells differing in CD45R expression. , 1992, Journal of immunology.
[507] R. Perlmutter,et al. Defective T cell receptor signaling in mice lacking the thymic isoform of p59 fyn , 1992, Cell.
[508] P. Stein,et al. pp59 fyn mutant mice display differential signaling in thymocytes and peripheral T cells , 1992, Cell.
[509] C. Crews,et al. Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[510] D. Pardoll,et al. Tyrosine kinase triggering in thymocytes undergoing positive selection , 1992, European journal of immunology.
[511] J. Farber,et al. Protection by cyclosporin A of cultured hepatocytes from the toxic consequences of the loss of mitochondrial energization produced by 1-methyl-4-phenylpyridinium. , 1992, Biochemical pharmacology.
[512] M. Colombel,et al. Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle. , 1992, Cancer research.
[513] C. June,et al. In vivo calcium elevations in thymocytes with T cell receptors that are specific for self ligands. , 1992, Science.
[514] B. Beutler,et al. Constitutive synthesis of tumor necrosis factor in the thymus. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[515] R. Black,et al. Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme , 1992, Cell.
[516] A. Wakeham,et al. Profound block in thymocyte development in mice lacking p56lck , 1992, Nature.
[517] P. Bernardi. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization. , 1992, The Journal of biological chemistry.
[518] S. Hedrick,et al. In vivo and in vitro clonal deletion of double-positive thymocytes , 1992, The Journal of experimental medicine.
[519] S. Snyder,et al. Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[520] Gerard I. Evan,et al. Induction of apoptosis in fibroblasts by c-myc protein , 1992, Cell.
[521] R. Kolesnick,et al. Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system. , 1992, Science.
[522] N. Copeland,et al. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis , 1992, Nature.
[523] M. Barbacid,et al. Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates , 1992, Nature.
[524] W. Paul,et al. Activation events during thymic selection , 1992, The Journal of experimental medicine.
[525] R. Perlmutter,et al. Disruption of CD8‐dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56lck , 1992, European journal of immunology.
[526] M. Zoratti,et al. Modulation of the mitochondrial megachannel by divalent cations and protons. , 1992, The Journal of biological chemistry.
[527] H. Stein,et al. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease , 1992, Cell.
[528] H. von Boehmer,et al. Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice , 1992, European journal of immunology.
[529] C. Janeway,et al. Isoform‐specific associations of CD45 with accessory molecules in human T lymphocytes , 1992, European journal of immunology.
[530] J. Downward,et al. The regulation and function of p21ras in T cells. , 1992, Immunology today.
[531] P. Johnson,et al. Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. , 1992, Journal of immunology.
[532] V. Fadok,et al. Apoptosis and programmed cell death in immunity. , 1992, Annual review of immunology.
[533] M. Karin,et al. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. , 1991, Biochimica et biophysica acta.
[534] M. Crompton,et al. Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A. , 1991, Journal of molecular and cellular cardiology.
[535] Suzanne Cory,et al. bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship , 1991, Cell.
[536] S. Korsmeyer,et al. bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes , 1991, Cell.
[537] G. Kroemer,et al. The fail-safe paradigm of immunological self-tolerance , 1991, The Lancet.
[538] R. Kolesnick,et al. Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[539] C. Boitard,et al. CD45RA antibodies split the CD3bright T cell subset. , 1991, International immunology.
[540] Jonathan A. Cooper,et al. Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src , 1991, Nature.
[541] D. Loh,et al. Receptor-stimulated death pathway is opened by antigen in mature T cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[542] R. Klausner,et al. T cell antigen receptor activation pathways: The tyrosine kinase connection , 1991, Cell.
[543] E. Krebs,et al. Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. , 1991, The Journal of biological chemistry.
[544] N. Shastri,et al. Requirement for association of p56 lck with CD4 in antigen-specific signal transduction in T cells , 1991, Cell.
[545] J. Cambier,et al. T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor. , 1991, Immunology today.
[546] G. Kroemer,et al. Interleukin-2, autotolerance, and autoimmunity. , 1991, Advances in immunology.
[547] A. Heimberger,et al. Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. , 1990, Science.
[548] M. Newell,et al. Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen , 1990, Nature.
[549] R. Kolesnick,et al. Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. Synthesis via ceramide from sphingomyelin. , 1990, The Journal of biological chemistry.
[550] R. Klausner,et al. Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[551] K. Horgan,et al. Hyporesponsiveness of “naive” (CD45RA+) human T cells to multiple receptor‐mediated stimuli but augmentation of responses by co‐stimuli , 1990, European journal of immunology.
[552] R. Perlmutter,et al. Interaction of the unique N-terminal region of tyrosine kinase p56 lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs , 1990, Cell.
[553] H. Macdonald,et al. Programmed death of autoreactive thymocytes , 1990, Nature.
[554] M. Cobb,et al. Evidence for insulin-dependent activation of S6 and microtubule-associated protein-2 kinases via a human insulin receptor/v-ros hybrid. , 1990, The Journal of biological chemistry.
[555] G. Crabtree,et al. Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link. , 1990, Annual review of immunology.
[556] R. Balderas,et al. Tolerance-related V beta clonal deletions in normal CD4-8-, TCR- alpha/beta + and abnormal lpr and gld cell populations , 1989, The Journal of experimental medicine.
[557] E. Puré,et al. Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[558] Beni M. Sahai,et al. Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes , 1989, Nature.
[559] S. Orrenius,et al. Calcium‐activated DNA fragmentation kills immature thymocytes , 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[560] S. Orrenius,et al. Calcium-activated DNA fragmentation in rat liver nuclei. , 1989, The Journal of biological chemistry.
[561] R. Fernald,et al. Circadian rhythm and light regulate opsin mRNA in rod photoreceptors , 1989, Nature.
[562] G. Crabtree. Contingent genetic regulatory events in T lymphocyte activation. , 1989, Science.
[563] R. Kofler,et al. Molecular genetics of murine lupus models. , 1989, Advances in immunology.
[564] Michael A. Bookman,et al. The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56 lck , 1988, Cell.
[565] J. Maller,et al. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II , 1988, Nature.
[566] G. Janossy,et al. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. , 1988, Journal of immunology.
[567] J. Sprent,et al. T Cell Selection in the Thymus , 1988, Immunological reviews.
[568] L. Lefrançois,et al. Developmental sequence of T200 antigen modifications in murine T cells. , 1987, Journal of immunology.
[569] P. Marrack,et al. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking , 1987, Nature.
[570] P. Marrack,et al. T cell tolerance by clonal elimination in the thymus , 1987, Cell.
[571] A. Theofilopoulos,et al. Murine models of systemic lupus erythematosus. , 1985, Advances in immunology.
[572] J. Cohen,et al. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. , 1984, Journal of immunology.
[573] A. Wyllie. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation , 1980, Nature.
[574] A. Jeffrey,et al. How the λ repressor and cro work , 1980, Cell.
[575] A. Wyllie,et al. Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics , 1972, British Journal of Cancer.
[576] G. Schatz,et al. The biogenesis of mitochondria. , 1970, The Biochemical journal.
[577] Albert Camus,et al. Le mythe de Sisyphe , 1942 .