Synthesis of novel 9-O-N-aryl/aryl-alkyl amino carbonyl methyl substituted berberine analogs and evaluation of DNA binding aspects.
暂无分享,去创建一个
[1] Jin-Yuarn Lin,et al. Protective effect of isoquinoline alkaloid berberine on spontaneous inflammation in the spleen, liver and kidney of non-obese diabetic mice through downregulating gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines , 2012 .
[2] Xiao-Ling Li,et al. Molecular spectroscopy evidence of berberine binding to DNA: comparative binding and thermodynamic profile of intercalation. , 2012, Biomacromolecules.
[3] G. S. Kumar,et al. Biophysical studies on the effect of the 13 position substitution of the anticancer alkaloid berberine on its DNA binding. , 2012, The journal of physical chemistry. B.
[4] M. Ferraroni,et al. X-Ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine complexed with double helix DNA d(CGTACG). , 2011, Chemical communications.
[5] G. S. Kumar,et al. Interaction of berberine, palmatine, coralyne, and sanguinarine to quadruplex DNA: a comparative spectroscopic and calorimetric study. , 2011, Biochimica et biophysica acta.
[6] G. S. Kumar,et al. Enhanced DNA binding of 9-ω-amino alkyl ether analogs from the plant alkaloid berberine. , 2011, DNA and cell biology.
[7] G. S. Kumar,et al. Thermodynamic profiles of the DNA binding of benzophenanthridines sanguinarine and ethidium: A comparative study with sequence specific polynucleotides , 2010 .
[8] G. S. Kumar,et al. Binding of the anticancer alkaloid sanguinarine to double stranded RNAs: insights into the structural and energetics aspects. , 2010, Molecular bioSystems.
[9] S. Tsao,et al. Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations. , 2009, Journal of ethnopharmacology.
[10] Maidul Hossain,et al. DNA intercalation of methylene blue and quinacrine: new insights into base and sequence specificity from structural and thermodynamic studies with polynucleotides. , 2009, Molecular bioSystems.
[11] Xiuping Chen,et al. A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs , 2009, Anti-cancer drugs.
[12] G. S. Kumar,et al. Interaction of isoquinoline alkaloids with an RNA triplex: structural and thermodynamic studies of berberine, palmatine, and coralyne binding to poly(U).poly(A)(*)poly(U). , 2009, The journal of physical chemistry. B.
[13] K. Bhadra,et al. Interaction of Isoquinoline Alkaloids with Polymorphic DNA Structures , 2009, Chemistry & biodiversity.
[14] G. S. Kumar,et al. DNA binding of benzophenanthridine compounds sanguinarine versus ethidium: Comparative binding and thermodynamic profile of intercalation , 2009 .
[15] J. Hong,et al. Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells. , 2009, International journal of oncology.
[16] Su Min Park,et al. Induction of apoptosis in human leukemia U937 cells by anthocyanins through down-regulation of Bcl-2 and activation of caspases. , 2009, International journal of oncology.
[17] J. Reymond,et al. On-bead cyclization in a combinatorial library of 15,625 octapeptides. , 2009, Bioorganic & medicinal chemistry.
[18] G. S. Kumar,et al. Spectroscopic and calorimetric studies on the binding of alkaloids berberine, palmatine and coralyne to double stranded RNA polynucleotides. , 2009, The journal of physical chemistry. B.
[19] G. S. Kumar,et al. DNA-binding cytotoxic alkaloids: comparative study of the energetics of binding of berberine, palmatine, and coralyne. , 2008, DNA and cell biology.
[20] K. Bhadra,et al. Berberine-DNA complexation: new insights into the cooperative binding and energetic aspects. , 2008, Biochimica et biophysica acta.
[21] Jin-Qiang Hou,et al. 9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc. , 2008, Bioorganic & medicinal chemistry.
[22] S. Maiti,et al. Binding of berberine to human telomeric quadruplex – spectroscopic, calorimetric and molecular modeling studies , 2008, The FEBS journal.
[23] H. Hosseinzadeh,et al. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine , 2008, Phytotherapy research : PTR.
[24] S. Kulkarni,et al. On the mechanism of antidepressant-like action of berberine chloride. , 2008, European journal of pharmacology.
[25] G. S. Kumar,et al. Self-structure induction in single stranded poly(A) by small molecules: Studies on DNA intercalators, partial intercalators and groove binding molecules. , 2008, Archives of biochemistry and biophysics.
[26] C. Jin,et al. Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimetry. , 2008, Journal of biochemical and biophysical methods.
[27] G. S. Kumar,et al. Binding of protoberberine alkaloid coralyne with double stranded poly(A): a biophysical study. , 2008, Molecular bioSystems.
[28] G. S. Kumar,et al. Thermodynamics of the binding of cytotoxic protoberberine molecule coralyne to deoxyribonucleic acids. , 2008, Biochimica et biophysica acta.
[29] G. S. Kumar,et al. Molecular aspects on the interaction of protoberberine, benzophenanthridine, and aristolochia group of alkaloids with nucleic acid structures and biological perspectives , 2007, Medicinal research reviews.
[30] Ying-Chih Lin,et al. Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. , 2007, Life sciences.
[31] G. S. Kumar,et al. Molecular recognition of DNA by small molecules: AT base pair specific intercalative binding of cytotoxic plant alkaloid palmatine. , 2007, Biochimica et biophysica acta.
[32] L. Cronin,et al. Microcalorimetry of interaction of dihydro-imidazo-phenanthridinium (DIP)-based compounds with duplex DNA. , 2007, Biophysical chemistry.
[33] Zhi-Hong Jiang,et al. Amplification of DNA-binding affinities of protoberberine alkaloids by appended polyamines. , 2007, Bioorganic & medicinal chemistry letters.
[34] A. Shirwaikar,et al. In vitro antioxidant studies on the benzyl tetra isoquinoline alkaloid berberine. , 2006, Biological & pharmaceutical bulletin.
[35] J. Chaires,et al. A thermodynamic signature for drug-DNA binding mode. , 2006, Archives of biochemistry and biophysics.
[36] L. Cipak,et al. Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells. , 2006, Cancer letters.
[37] S. Neidle,et al. Natural and synthetic G-quadruplex interactive berberine derivatives. , 2006, Bioorganic & medicinal chemistry letters.
[38] G. S. Kumar,et al. The binding of DNA intercalating and non-intercalating compounds to A-form and protonated form of poly(rC).poly(rG): spectroscopic and viscometric study. , 2006, Bioorganic & medicinal chemistry.
[39] Wen-Hua Chen,et al. Synthesis and DNA-binding affinities of monomodified berberines. , 2005, Bioorganic & medicinal chemistry.
[40] Z. Cai,et al. Synthesis of linked berberine dimers and their remarkably enhanced DNA-binding affinities. , 2005, Bioorganic & medicinal chemistry letters.
[41] L. A. Jacobson,et al. Structural and thermodynamic strategies for site-specific DNA binding proteins. , 2000, Structure.
[42] K. Bastow,et al. The 9-position in berberine analogs is an important determinant of DNA topoisomerase II inhibition. , 2000, Anti-cancer drug design.
[43] J. Chaires,et al. Energetics of DNA intercalation reactions. , 2000, Biochemistry.
[44] A. R. Srinivasan,et al. Human topoisomerase I poisoning by protoberberines: potential roles for both drug-DNA and drug-enzyme interactions. , 2000, Biochemistry.
[45] F. Murphy,et al. Nonsequence-specific DNA recognition: a structural perspective. , 2000, Structure.
[46] A. Gilani,et al. Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. , 2000, Fitoterapia.
[47] B. Tomlinson,et al. The Antihypertensive Effect of the Berberine Derivative 6-Protoberberine in Spontaneously Hypertensive Rats , 1999, Pharmacology.
[48] A. R. Srinivasan,et al. Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs. , 1997, Biochemistry.
[49] G. Kelly,et al. Berberine: Therapeutic Potential of an Alkaloid Found in Several Medicinal Plants , 1997 .
[50] David J Brayden,et al. Non-antibiotic anti-diarrhoeal drugs: factors affecting oral bioavailability of berberine and loperamide in intestinal tissue , 1997 .
[51] Rosenblum Ml,et al. Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors. , 1990 .
[52] D. Crothers,et al. Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid. , 1982, Biochemistry.
[53] K. Chaudhuri,et al. Sanguinarine: a monofunctional intercalating alkaloid , 1982, FEBS letters.
[54] T. Lohman,et al. Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity , 1978, Quarterly Reviews of Biophysics.
[55] P. V. von Hippel,et al. Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice. , 1974, Journal of molecular biology.
[56] L. Lerman,et al. Structural considerations in the interaction of DNA and acridines. , 1961, Journal of molecular biology.
[57] G. S. Kumar,et al. Protoberberine Alkaloids: Physicochemical and Nucleic Acid Binding Properties , 2007 .
[58] Lenka Gryčová,et al. Quaternary protoberberine alkaloids. , 2007, Phytochemistry.
[59] Hye-Sook Kim,et al. Antimalarial activity and structure-activity relationships of protoberberine alkaloids , 1998 .
[60] C. Y. Huang. Determination of binding stoichiometry by the continuous variation method: the Job plot. , 1982, Methods in enzymology.