Evaluation of Artificial Neural Networks in Prediction of Essential Hypertension

This paper investigates the ability of variously designed & trained Artificial Neural Network (ANN) to predict the probability of occurrence of Hypertension (HT) in a mixed (healthy + hypertensive, both sexes) patient population. To do this a multi layer feed-forward neural network with 13 inputs and 1 output was created with multiple hidden layers. Network parameters such as count of hidden layers, count of neurons in the hidden layers, percentage of testing samples and percentage of samples used for validation were varied so as to deliver the maximum prediction accuracy of the ANN network. The training algorithm used for ANN is LevenbergMarquardt back propagation algorithm. A large database, comprising healthy and hypertensive patients from a university hospital was used for training the ANN and prediction. The maximum accuracy marked by this approach was 92.85%, considered quite satisfactory by medical experts. Thus the best network parameter choice best for ANNs approached empirically. General Terms ANN Classification, Diagnosis

[1]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[2]  Xiaojin Zhu,et al.  --1 CONTENTS , 2006 .

[3]  Rahul Samant,et al.  Effects of Missing Data Imputation on Classifier Accuracy , 2013 .

[4]  Rüdiger W. Brause,et al.  Medical Analysis and Diagnosis by Neural Networks , 2001, ISMDA.

[5]  D. Voth Using AI to detect breast cancer , 2005, IEEE Intelligent Systems.

[6]  Thu-Hua Liu,et al.  A case-based classifier for hypertension detection , 2011, Knowl. Based Syst..

[7]  David Gil Méndez,et al.  Application of artificial neural networks in the diagnosis of urological dysfunctions , 2009, Expert Syst. Appl..

[8]  Marco Furini,et al.  International Journal of Computer and Applications , 2010 .

[9]  Rahul Samant,et al.  A study on Feature Selection Methods in Medical Decision Support Systems , 2013 .

[10]  Armando Eduardo De Giusti,et al.  Pattern recognition in medical images using neural networks , 2001 .

[11]  S. Oparil,et al.  Essential hypertension. Part I: definition and etiology. , 2000, Circulation.

[12]  Wim Wiegerinck Clinical Applications of Artificial Neural Networks: Richard Dybowski, Vanya Gant (Eds.), Cambridge University Press, Cambridge, UK, New York, Oakleigh, Madrid, Cape Town, 2001, 378 pp., 55 figures, 25 tables, Hardcover, ISBN 0521662710 , 2003, Artif. Intell. Medicine.

[13]  Richard Dybowski,et al.  Clinical applications of artificial neural networks: Theory , 2001 .

[14]  Xin Zhang,et al.  A Computer Aided Diagnosis System in Mammography Using Artificial Neural Networks , 2008, 2008 International Conference on BioMedical Engineering and Informatics.

[15]  Carlos J. Perez,et al.  Computer-aided diagnosis system: A Bayesian hybrid classification method , 2013, Comput. Methods Programs Biomed..

[16]  J. Jonathan,et al.  A TWO TIER NEURAL INTERNETWORK BASED APPROACH TO MEDICAL DIAGNOSIS USING K-NEAREST NEIGHBOR CLASSIFICATION FOR DIAGNOSIS PRUNING , 2007 .

[17]  Kai Liu,et al.  A novel large-memory neural network as an aid in medical diagnosis applications , 2001, IEEE Transactions on Information Technology in Biomedicine.

[18]  Heekuck Oh,et al.  Neural Networks for Pattern Recognition , 1993, Adv. Comput..

[19]  Frank C. Lin,et al.  Medical diagnosis by the virtual physician , 1999, Proceedings 12th IEEE Symposium on Computer-Based Medical Systems (Cat. No.99CB36365).

[20]  Mevlut Ture,et al.  Comparing classification techniques for predicting essential hypertension , 2005, Expert Syst. Appl..

[21]  Qeethara Al-Shayea Artificial Neural Networks in Medical Diagnosis , 2024, International Journal of Research Publication and Reviews.

[22]  G GUIMARAES,et al.  Essential hypertension , 1950, Revue de medecine aeronautique.