Outcomes of silver nitrate use in perianal fistula: are perianal fistulas still a nightmare for surgeons?

INTRODUCTION In this study, we aimed to evaluate outcomes of % 20 silver nitrate (SNS) application in perianal fistula patients. MATERIAL AND METHOD All patients who received 20 % SNS treatment for intersphincteric and transsphincteric fistulas between January 2017 and December 2017 were included in our study. Patients were invited for control examinations after one week. Patients with continued discharges after single dose of SNS kept receiving solution six more times with one month intervals. Stopping of discharges were considered as finalization of the study. Cases with discharges after 6 episodes of SNS were described as insufficient healing. The patients were grouped according to healing status (healing patients in Group 1, non-healing patients in Group 2) .Gender, age, follow-up times, date of the complaint start, number of SNS application, type of fistula and frequency of fistula discharge were recorded. RESULTS A total of 49 patients were included in this study. Forty-four (% 89.8) of them were male. The mean age was 44.9. Twenty-eight patients (57.1%) had intersphincteric fistulas, while twenty-two patients (42.9%) had intersfinteric fistulas. Mean number of SNS application was 4.1 (1-6). Patients in Group 1 had mean number of SNS therapy as 3.42 (1-6), whereas cases in Group 2 this number was 5.5 (3-6). Patients were observed approximately for 8.84 months (6-12). We were able to reach sufficient healing in 13 (%26) cases via 2 times and 20 (%40) cases via 3-6 times application of SNS. CONCLUSION We were able to reach complete healing rates as % 67 with SNS application in perianal fistula. This is a non-invasive procedure and could be applied in out patient clinics, with low costs. Less complication rates enhances attraction. Patients will not loose chance of surgical treatment. Therefore, we believe SNS may be used as first line treatment in perianal fistulas. KEY WORDS Follow-up, Perianal fistula, Silver nitrate.

[1]  Parvez Sheikh,et al.  Management of Fistula-in-Ano—The Current Evidence , 2014, Indian Journal of Surgery.

[2]  B. Gulluoglu,et al.  Should We Consider Topical Silver Nitrate Irrigation as a Definitive Nonsurgical Treatment for Perianal Fistula? , 2014, Diseases of the colon and rectum.

[3]  S. Wexner,et al.  Ligation of intersphincteric fistula tract (LIFT) to treat anal fistula: systematic review and meta-analysis , 2014, Techniques in Coloproctology.

[4]  P. Lunniss,et al.  Ligation of the intersphincteric fistula tract in the management of anal fistula. A systematic review , 2013, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[5]  Paiboon Jivapaisarnpong,et al.  Ligation of intersphincteric fistula tract and its modification: Results from treatment of complex fistula. , 2013, World journal of gastrointestinal surgery.

[6]  S. Alasari,et al.  Overview of anal fistula and systematic review of ligation of the intersphincteric fistula tract (LIFT) , 2013, Techniques in Coloproctology.

[7]  L. Bartlett,et al.  Ligation of intersphincteric fistula tract compared with advancement flap for complex anorectal fistulas requiring initial seton drainage. , 2012, American journal of surgery.

[8]  V. Pasta,et al.  Personal technique for treatment of perianal fistulas in outpatients. , 2012, Annali italiani di chirurgia.

[9]  Andreas Ommer,et al.  Cryptoglandular anal fistulas. , 2011, Deutsches Arzteblatt international.

[10]  W. Bemelman,et al.  Histological identification of epithelium in perianal fistulae: a prospective study , 2010, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[11]  Eric K. Johnson,et al.  Anorectal abscess and fistula-in-ano: evidence-based management. , 2010, The Surgical clinics of North America.

[12]  R. Nelson,et al.  Surgical management of anal fistulae: a systematic review , 2008, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[13]  H. Leong,et al.  Recurrence pattern of fistula-in-ano in a Chinese population. , 2008, Journal of gastrointestinal and liver diseases : JGLD.

[14]  M. Keighley,et al.  Surgical intervention for chronic anorectal fistula , 2007 .

[15]  P. Soeters,et al.  Long-term outcome following mucosal advancement flap for high perianal fistulas and fistulotomy for low perianal fistulas , 2006, International Journal of Colorectal Disease.

[16]  D. Godevenos,et al.  Quality of life of patients after surgical treatment of anal fistula; the role of anal manometry , 2001, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[17]  J. Garcia-Aguilar,et al.  Cutting seton versus two‐stage seton fistulotomy in the surgical management of high anal fistula , 1998, The British journal of surgery.

[18]  A. Parks Pathogenesis and Treatment of Fistula-in-Ano , 1961 .

[19]  F. Stelzner,et al.  [Results in radical surgery of 143 anal fistulas; criticism of one-stage sphincterotomy in one-stage or multiple-stage surgery of fistulas]. , 1956, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.