The association between blood pressure and serum cholesterol in healthy men: the Oslo study.

The association between serum cholesterol and blood pressure (BP) has been studied in 16 525 men. The study reveals that these Oslo men in their forties present with a serum cholesterol value which is on average 0.71 mmol/l (27.4 mg/100 ml) higher at diastolic BP greater than 110 mmHg than at BP less than 70 mmHg. According to earlier studies in Oslo, this cholesterol difference alone imparts a 10-year myocardial infarction morbidity difference of 25--30%. These findings might be of practical importance for epidemiological studies and for preventive measures against the two factors. The influence of other variables on the association between blood pressure and cholesterol has been studied in a multivariate analysis. Of these variables, only body mass index and serum triglycerides significantly influence the relationship between blood pressure and cholesterol, whereas age, cigarette smoking, non-fasting blood sugar, season, socioeconomic status, and physical activity at work and leisure do not influence the correlation.

[1]  I. Holme,et al.  The Oslo study. Cardiovascular disease in middle-aged and young Oslo men. , 1975, Acta medica Scandinavica. Supplementum.

[2]  M. Kornitzer,et al.  CORONARY RISK FACTORS AND SOCIOECONOMIC STATUS , 1977, The Lancet.

[3]  H. Blackburn,et al.  Cardiovascular survey methods. , 1969, Monograph series. World Health Organization.

[4]  P. Owren,et al.  A controlled trial of the effect of linolenic acid on incidence of coronary heart disease. The Norwegian vegetable oil experiment of 1965-66. , 1968, Scandinavian journal of clinical and laboratory investigation. Supplementum.

[5]  S. Lindstedt,et al.  The Stockholm prospective study. 1. The initial values for plasma lipids. , 1968, Acta medica Scandinavica. Supplementum.

[6]  R M Acheson,et al.  Blood pressure as it relates to physique, blood glucose, and serum cholesterol. , 1969, Vital and health statistics. Series 11, Data from the National Health Survey.

[7]  L. Wilhelmsen,et al.  Multivariate Analysis of Risk Factors for Coronary Heart Disease , 1973, Circulation.

[8]  Florey Cdu,et al.  Blood pressure as it relates to physique, blood glucose, and serum cholesterol. , 1969 .

[9]  G. Pincherle,et al.  Mean blood pressure and its relation to other factors determined at a routine executive health examination. , 1974, Journal of chronic diseases.

[10]  Anthony Ralston,et al.  Mathematical Methods for Digital Computers , 1960 .

[11]  L. Hagerup.  Coronary heart disease risk factors in men and women. From the population study in Glostrup, Denmark. , 1974, Acta medica Scandinavica. Supplementum.

[12]  D. E. Lamphiear,et al.  Coronary Risk Factors in a Community: Findings in Tecumseh, Michigan , 1976, Circulation.

[13]  I. Holme,et al.  The intercorrelation of serum cholesterol, cigarette smoking and body weight. The Oslo Study. , 2009, Acta medica Scandinavica.

[14]  I. Holme,et al.  CORONARY RISK FACTORS AND SOCIOECONOMIC STATUS , 1977, The Lancet.

[15]  M. Everitt,et al.  The relationship between blood pressure and biochemical risk factors in a general population. , 1976, British journal of preventive & social medicine.

[16]  I. Holme,et al.  CORONARY RISK FACTORS AND SOCIOECONOMIC STATUS The Oslo Study , 1976, The Lancet.

[17]  R. Nicolaysen,et al.  Ten-year mortality and morbidity related to serum cholesterol. A follow-up of 3.751 men aged 40-49. , 1972, Scandinavian journal of clinical and laboratory investigation. Supplementum.