Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase.
暂无分享,去创建一个
[1] J. Weuve,et al. Serum total bilirubin level, prevalent stroke, and stroke outcomes: NHANES 1999-2004. , 2008, The American journal of medicine.
[2] R. Takayanagi,et al. Relationship between Gilbert syndrome and prevalence of vascular complications in patients with diabetes. , 2007, JAMA.
[3] R. Takayanagi,et al. Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice. , 2007, Kidney international.
[4] Hung-Yi Chen,et al. Melatonin decreases neurovascular oxidative/nitrosative damage and protects against early increases in the blood–brain barrier permeability after transient focal cerebral ischemia in mice , 2006, Journal of pineal research.
[5] H. Abboud,et al. Nox4 NAD(P)H Oxidase Mediates Hypertrophy and Fibronectin Expression in the Diabetic Kidney* , 2005, Journal of Biological Chemistry.
[6] S. Bloc,et al. Bilirubin decreases NOS2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] T. Morita. Heme Oxygenase and Atherosclerosis , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[8] H. Utsumi,et al. Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurement. , 2005, Free radical biology & medicine.
[9] N. Abraham,et al. Heme oxygenase and the cardiovascular-renal system. , 2005, Free radical biology & medicine.
[10] H. Nawata,et al. NAD(P)H Oxidase Activation: A Potential Target Mechanism for Diabetic Vascular Complications, Progressive β-Cell Dysfunction and Metabolic Syndrome , 2005 .
[11] R. Stocker. Antioxidant activities of bile pigments. , 2004, Antioxidants & redox signaling.
[12] S. Matsumoto,et al. Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesity. , 2004, Free radical biology & medicine.
[13] S. Araki,et al. Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy. , 2003, Diabetes.
[14] H. Nawata,et al. Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment , 2003, Diabetologia.
[15] H. Utsumi,et al. Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase. , 2003, Journal of the American Society of Nephrology : JASN.
[16] R. Clempus,et al. Vascular NAD(P)H oxidases: specific features, expression, and regulation. , 2003, American journal of physiology. Regulatory, integrative and comparative physiology.
[17] C. Betsholtz,et al. A new method for large scale isolation of kidney glomeruli from mice. , 2002, The American journal of pathology.
[18] H. Nawata,et al. Accumulation of 8-hydroxy-2'-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats. , 2002, Diabetes.
[19] C. Kim,et al. Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes. , 2002, Diabetes.
[20] T. Münzel,et al. Mechanisms Underlying Endothelial Dysfunction in Diabetes Mellitus , 2001, Circulation research.
[21] M. Hattori,et al. A Novel Superoxide-producing NAD(P)H Oxidase in Kidney* , 2001, The Journal of Biological Chemistry.
[22] H. Utsumi,et al. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells. , 2000, Diabetes.
[23] P. Várnai,et al. Identification of renox, an NAD(P)H oxidase in kidney. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[24] J. Zweier,et al. Validation of Lucigenin (Bis-N-methylacridinium) as a Chemilumigenic Probe for Detecting Superoxide Anion Radical Production by Enzymatic and Cellular Systems* , 1998, The Journal of Biological Chemistry.
[25] S. Hunt,et al. Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease. , 1996, Arteriosclerosis, thrombosis, and vascular biology.
[26] S. Ebrahim,et al. Serum bilirubin and risk of ischemic heart disease in middle-aged British men. , 1995, Clinical chemistry.
[27] F. Ziyadeh,et al. Role of transforming growth factor beta in diabetic nephropathy. , 1994, Experimental nephrology.
[28] K. H. Kim,et al. DNA damage in the kidneys of diabetic rats exhibiting microalbuminuria. , 1994, Free radical biology & medicine.
[29] J. Baynes. Role of Oxidative Stress in Development of Complications in Diabetes , 1991, Diabetes.
[30] K. Takeshige,et al. Bilirubin inhibits the activation of superoxide-producing NADPH oxidase in a neutrophil cell-free system. , 1991, Biochimica et biophysica acta.
[31] B. Ames,et al. Bilirubin is an antioxidant of possible physiological importance. , 1987, Science.
[32] G. Lippi,et al. Relationship of serum bilirubin concentrations to kidney function and albuminuria in the United States adult population. Findings from the National Health and Nutrition Examination Survey 2001–2006 , 2009, Clinical chemistry and laboratory medicine.
[33] K. Griendling,et al. Smooth Muscle Cells , 2005 .
[34] H. Nawata,et al. NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome. , 2005, Current drug targets.
[35] S. Wolff,et al. Protein glycation and oxidative stress in diabetes mellitus and ageing. , 1991, Free radical biology & medicine.
[36] R. Stocker,et al. Induction of haem oxygenase as a defence against oxidative stress. , 1990, Free radical research communications.
[37] L. Oberley. Free radicals and diabetes. , 1988, Free radical biology & medicine.