A Consensus Statement of the Society of Thoracic Radiology: Screening for Lung Cancer with Helical Computed Tomography

This consensus statement by the Society of Thoracic Radiology is a summary of the current understanding of low dose computed tomography (CT) for screening for lung cancer. Lung cancer is the most common fatal malignancy in the industrialized world. Unlike the next three most common cancers, screening for lung cancer is not currently recommended by cancer organizations. Improvements in CT technology make lung screening feasible. Early prevalence data indicate that about two-thirds of lung cancers that are detected by CT screening are at an early stage. Other data support the postulate that patients with lung cancers detected at this early stage have better rates of survival. Whether this will translate into an improved disease specific mortality is yet to be demonstrated. The suggested technical protocols, selection criteria, and method of handling the numerous benign nodules that are detected are discussed. It is the consensus of this committee that mass screening for lung cancer with CT is not currently advocated. Suitable subjects who wish to participate should be encouraged to do so in controlled trials, so that the value of CT screening can be ascertained as soon as possible.

[1]  C. Mountain,et al.  Prognostic implications of the International Staging System for Lung Cancer. , 1988, Seminars in oncology.

[2]  Kenji Suzuki,et al.  Conventional clinicopathologic prognostic factors in surgically resected nonsmall cell lung carcinoma , 1999, Cancer.

[3]  R. Dodge.  Sensitivity of methacholine testing in occupational asthma. , 1986, Chest.

[4]  D. Sugarbaker,et al.  Screening for Lung Cancer: Another Look; A Different View , 1997 .

[5]  W F Taylor,et al.  Early lung cancer detection: results of the initial (prevalence) radiologic and cytologic screening in the Mayo Clinic study. , 2015, The American review of respiratory disease.

[6]  P C Goodman,et al.  Correlation of tumor size and survival in patients with stage IA non-small cell lung cancer. , 2000, Chest.

[7]  A. Sakurada,et al.  Prognostic assessment of 1310 patients with non-small-cell lung cancer who underwent complete resection from 1980 to 1993. , 1998, The Journal of thoracic and cardiovascular surgery.

[8]  Feng Li,et al.  Mass screening for lung cancer with mobile spiral computed tomography scanner , 1998, The Lancet.

[9]  Taylor Murray,et al.  Cancer statistics, 2000 , 2000, CA: a cancer journal for clinicians.

[10]  R. Coleman,et al.  Focal pulmonary abnormalities: evaluation with F-18 fluorodeoxyglucose PET scanning. , 1993, Radiology.

[11]  W. C. Ball,et al.  Early lung cancer detection: results of the initial (prevalence) radiologic and cytologic screening in the Johns Hopkins study. , 2015, The American review of respiratory disease.

[12]  O. Miettinen,et al.  Early Lung Cancer Action Project: overall design and findings from baseline screening , 1999, The Lancet.

[13]  Melvyn S. Tockman,et al.  Survival and Mortality from Lung Cancer in a Screened Population: The Johns Hopkins Study , 1986 .

[14]  B J Flehinger,et al.  Early lung cancer detection: results of the initial (prevalence) radiologic and cytologic screening in the Memorial Sloan-Kettering study. , 2015, The American review of respiratory disease.

[15]  M E Burt,et al.  Incidence of local recurrence and second primary tumors in resected stage I lung cancer. , 1995, The Journal of thoracic and cardiovascular surgery.

[16]  H. Ohmatsu,et al.  Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography. , 1996, Radiology.

[17]  R. Dziadziuszko,et al.  Results of surgical treatment of non-small cell lung cancer: validation of the new postoperative pathologic TNM classification. , 2000, The Journal of thoracic and cardiovascular surgery.

[18]  M. Melamed,et al.  The effect of surgical treatment on survival from early lung cancer. Implications for screening. , 1992, Chest.

[19]  D. Sugarbaker,et al.  Chest X-ray screening improves outcome in lung cancer. A reappraisal of randomized trials on lung cancer screening. , 1995, Chest.

[20]  G. Byrnes,et al.  Screening for lung cancer. , 2004, The Cochrane database of systematic reviews.

[21]  J. Roth,et al.  Survival in early-stage non-small cell lung cancer. , 1995, The Annals of thoracic surgery.

[22]  J Polák,et al.  Lung cancer detection results of a randomized prospective study in Czechoslovakia , 1986, Cancer.

[23]  C. Mountain,et al.  Revisions in the International System for Staging Lung Cancer. , 1997, Chest.

[24]  S J Swensen,et al.  Lung nodule enhancement at CT: prospective findings. , 1996, Radiology.

[25]  E. Bergstralh,et al.  Screening for lung cancer. A critique of the mayo lung project , 1991, Cancer.

[26]  R. G. Fraser,et al.  DIAGNOSIS OF DISEASES OF THE CHEST , 1978, The Ulster Medical Journal.

[27]  D. Winchester,et al.  The National Cancer Data Base report on lung cancer , 1996, Cancer.