Elastolytic activity of cysteine cathepsins K, S, and V promotes vascular calcification

[1]  L. Pavone,et al.  Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy , 2020, Cells.

[2]  M. Kawaichi,et al.  Loss of HtrA1 serine protease induces synthetic modulation of aortic vascular smooth muscle cells , 2018, PloS one.

[3]  U. Querfeld,et al.  Collagen XIV and a related recombinant fragment protect human vascular smooth muscle cells from calcium‐/phosphate‐induced osteochondrocytic transdifferentiation , 2017, Experimental cell research.

[4]  Hui Huang,et al.  Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2 , 2016, Oncotarget.

[5]  Á. Millán,et al.  Critical Parameters of the In Vitro Method of Vascular Smooth Muscle Cell Calcification , 2015, PloS one.

[6]  K. Boström,et al.  Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification. , 2015, Circulation research.

[7]  V. Shastri,et al.  Matrix-metalloproteinase-9 is cleaved and activated by Cathepsin K , 2015, BMC Research Notes.

[8]  P. Libby,et al.  Selective cathepsin S inhibition attenuates atherosclerosis in apolipoprotein E-deficient mice with chronic renal disease. , 2015, The American journal of pathology.

[9]  A. Newby.  Proteinases and plaque rupture: unblocking the road to translation , 2014, Current opinion in lipidology.

[10]  M. Fonović,et al.  Cysteine cathepsins and extracellular matrix degradation. , 2014, Biochimica et biophysica acta.

[11]  L. Duca,et al.  Elastin fragmentation and atherosclerosis progression: the elastokine concept. , 2013, Trends in cardiovascular medicine.

[12]  M. Yacoub,et al.  Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification. , 2013, Nature materials.

[13]  C. Giachelli,et al.  Vascular Calcification: An Update on Mechanisms and Challenges in Treatment , 2013, Calcified Tissue International.

[14]  A. Khan,et al.  Raman Spectroscopy of Natural Bone and Synthetic Apatites , 2013 .

[15]  Hongbin Li,et al.  Effects of Cysteine Proteases on the Structural and Mechanical Properties of Collagen Fibers* , 2013, The Journal of Biological Chemistry.

[16]  L. Martiny,et al.  Interaction between the Elastin Peptide VGVAPG and Human Elastin Binding Protein* , 2012, The Journal of Biological Chemistry.

[17]  C. Farquharson,et al.  Mechanisms and Clinical Consequences of Vascular Calcification , 2012, Front. Endocrin..

[18]  A. Pujia,et al.  Serum calcium level is related to both intima-media thickness and carotid atherosclerosis: a neglect risk factor in obese/overweight subjects , 2012, Journal of Translational Medicine.

[19]  K. Okumura,et al.  Cysteine protease cathepsins in atherosclerosis-based vascular disease and its complications. , 2011, Hypertension.

[20]  C. Alvira,et al.  Neutrophil elastase is produced by pulmonary artery smooth muscle cells and is linked to neointimal lesions. , 2011, The American journal of pathology.

[21]  C. Patterson,et al.  MOVAS-1 cell line: a new in vitro model of vascular calcification. , 2011, International journal of molecular medicine.

[22]  B. Kestenbaum,et al.  Phosphate and cardiovascular disease. , 2011, Advances in chronic kidney disease.

[23]  L. Martiny,et al.  Elastin Peptides Signaling Relies on Neuraminidase-1-Dependent Lactosylceramide Generation , 2010, PloS one.

[24]  T. Reinheckel,et al.  Specialized roles for cysteine cathepsins in health and disease. , 2010, The Journal of clinical investigation.

[25]  M. Percival,et al.  Pharmacological Inhibition of Cathepsin S Decreases Atherosclerotic Lesions in Apoe-/- Mice , 2010, Journal of cardiovascular pharmacology.

[26]  J. Chambers,et al.  Aortic stenosis and lipids: does intervention work? , 2010, Current opinion in cardiology.

[27]  R. Neubert,et al.  Degradation of tropoelastin by matrix metalloproteinases – cleavage site specificities and release of matrikines , 2010, The FEBS journal.

[28]  P. Libby,et al.  Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease , 2009, Circulation.

[29]  B. Kestenbaum,et al.  Serum phosphorus concentrations and arterial stiffness among individuals with normal kidney function to moderate kidney disease in MESA. , 2009, Clinical journal of the American Society of Nephrology : CJASN.

[30]  P. Saftig,et al.  Role of cathepsin K in structural changes in brachiocephalic artery during progression of atherosclerosis in apoE-deficient mice. , 2008, Atherosclerosis.

[31]  Yin Tintut,et al.  Vascular calcification: pathobiology of a multifaceted disease. , 2008, Circulation.

[32]  M. Daemen,et al.  Cathepsin cysteine proteases in cardiovascular disease , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[33]  D. Simionescu,et al.  Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. , 2007, The American journal of pathology.

[34]  R. D'Agostino,et al.  Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. , 2007, Archives of internal medicine.

[35]  Daniel S Berman,et al.  Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients. , 2007, Journal of the American College of Cardiology.

[36]  Christoph Peters,et al.  Cathepsin L Deficiency Reduces Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Knockout Mice , 2007, Circulation.

[37]  H. Jo,et al.  Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis. , 2007, American journal of physiology. Heart and circulatory physiology.

[38]  Kui Wang,et al.  Fibronectin enhances in vitro vascular calcification by promoting osteoblastic differentiation of vascular smooth muscle cells via ERK pathway , 2006, Journal of cellular biochemistry.

[39]  R. Bischoff,et al.  Study of human lung elastin degradation by different elastases using high-performance liquid chromatography/mass spectrometry. , 2006, Analytical biochemistry.

[40]  L. Matrisian,et al.  Matrix Metalloproteinase Inhibition Attenuates Aortic Calcification , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[41]  John H. Zhang,et al.  Cathepsin and Calpain Inhibitor E64d Attenuates Matrix Metalloproteinase-9 Activity After Focal Cerebral Ischemia in Rats , 2006, Stroke.

[42]  I. van der Made,et al.  Disruption of the Cathepsin K Gene Reduces Atherosclerosis Progression and Induces Plaque Fibrosis but Accelerates Macrophage Foam Cell Formation , 2005, Circulation.

[43]  M. Pfeffer,et al.  Relation Between Serum Phosphate Level and Cardiovascular Event Rate in People With Coronary Disease , 2005, Circulation.

[44]  N. Vyavahare,et al.  Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells. , 2005, Biochemical and biophysical research communications.

[45]  A. Hofman,et al.  Coronary Calcification Improves Cardiovascular Risk Prediction in the Elderly , 2005, Circulation.

[46]  J. Pasteris,et al.  A mineralogical perspective on the apatite in bone , 2005 .

[47]  Matthew Bogyo,et al.  Cathepsin V, a Novel and Potent Elastolytic Activity Expressed in Activated Macrophages* , 2004, Journal of Biological Chemistry.

[48]  Makoto Naito,et al.  Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. , 2003, The Journal of clinical investigation.

[49]  S. Mochizuki,et al.  Signaling Pathways Transduced through the Elastin Receptor Facilitate Proliferation of Arterial Smooth Muscle Cells* , 2002, The Journal of Biological Chemistry.

[50]  M. Lauer,et al.  Effect of Hydroxymethylglutaryl Coenzyme A Reductase Inhibitors on the Progression of Calcific Aortic Stenosis , 2001, Circulation.

[51]  D. Sane,et al.  Arterial calcification: A review of mechanisms, animal models, and the prospects for therapy , 2001, Medicinal research reviews.

[52]  Frederick J. Schoen,et al.  Elastin calcification and its prevention with aluminum chloride pretreatment. , 1999, The American journal of pathology.

[53]  P. Libby,et al.  Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells. , 1998, The Journal of clinical investigation.

[54]  H. Kirschke,et al.  Lysosomal cysteine proteinases. , 1998, Ciba Foundation symposium.

[55]  D. Urry,et al.  Calcium ion effects a notable change in elastin conformation by interacting at neutral sites. , 1971, Biochemical and biophysical research communications.

[56]  M. Hayashi,et al.  Impact of circulating cathepsin K on the coronary calcification and the clinical outcome in chronic kidney disease patients , 2014, Heart and Vessels.

[57]  R. Neubert,et al.  The action of neutrophil serine proteases on elastin and its precursor. , 2012, Biochimie.

[58]  L. Demer.  Pathobiology of a Multifaceted Disease , 2008 .

[59]  C. Eisenberg,et al.  Toward cell therapy for vascular calcification: osteoclast-mediated demineralization of calcified elastin. , 2007, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[60]  H. C. Stary.  Natural history of calcium deposits in atherosclerosis progression and regression , 2000, Zeitschrift für Kardiologie.

[61]  M. Mcgrath.  The lysosomal cysteine proteases. , 1999, Annual review of biophysics and biomolecular structure.