Characterization of Cardiac Conduction System Abnormalities in Mice with Targeted Disruption of Six5 Gene

[1]  J. Triedman,et al.  Induction of atrial tachycardia and fibrillation in the mouse heart. , 2001, Cardiovascular research.

[2]  I. Anand,et al.  High output cardiac failure , 2001, Current treatment options in cardiovascular medicine.

[3]  F. Giubilei,et al.  Natural history of cardiac involvement in myotonic dystrophy: Correlation with CTG repeats , 2000, Neurology.

[4]  R. J. White,et al.  Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat. , 2000, Science.

[5]  J K Triedman,et al.  Phenotypic screening for heart rate variability in the mouse. , 2000, American journal of physiology. Heart and circulatory physiology.

[6]  C. Berul,et al.  Progressive Atrioventricular Conduction Block in a Mouse Myotonic Dystrophy Model , 2000, Journal of Interventional Cardiac Electrophysiology.

[7]  K. Fischbeck,et al.  Triplet repeat expansion in neuromuscular disease , 2000, Muscle and Nerve.

[8]  John I. Clark,et al.  Mice deficient in Six5 develop cataracts: implications for myotonic dystrophy , 2000, Nature Genetics.

[9]  Y. Chai,et al.  Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts , 2000, Nature Genetics.

[10]  L. Fauchier,et al.  Is it possible to identify infrahissian cardiac conduction abnormalities in myotonic dystrophy by non-invasive methods? , 1999, Heart.

[11]  S. Tominaga,et al.  Cooperation of Six and Eya in Activation of Their Target Genes through Nuclear Translocation of Eya , 1999, Molecular and Cellular Biology.

[12]  Paul J. Wang,et al.  Localization of the Sites of Conduction Abnormalities in a Mouse Model of Myotonic Dystrophy , 1999, Journal of cardiovascular electrophysiology.

[13]  D. Housman,et al.  DMPK dosage alterations result in atrioventricular conduction abnormalities in a mouse myotonic dystrophy model. , 1999, The Journal of clinical investigation.

[14]  T. Cooper,et al.  Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy. , 1998, Science.

[15]  G. Mitchell,et al.  Measurement of heart rate and Q-T interval in the conscious mouse. , 1998, American journal of physiology. Heart and circulatory physiology.

[16]  Yuji Hayashi,et al.  Cardiac abnormalities and cytosine-thymine-guanine trinucleotide repeats in myotonic dystrophy. , 1997, American heart journal.

[17]  S. Tapscott,et al.  Trinucleotide repeat expansion at the myotonic dystrophy locus reduces expression of DMAHP , 1997, Nature Genetics.

[18]  R. Moxley,et al.  Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP gene , 1997, Nature Genetics.

[19]  D. Housman,et al.  Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[20]  D. Wells,et al.  Characterisation of expression of mDMAHP, a homeodomain-encoding gene at the murine DM locus. , 1997, Human molecular genetics.

[21]  P. J. Wang,et al.  In vivo cardiac electrophysiology studies in the mouse. , 1996, Circulation.

[22]  D. Housman,et al.  Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy , 1996, Nature Genetics.

[23]  T. Ashizawa,et al.  Cardiac involvement in a large kindred with myotonic dystrophy. Quantitative assessment and relation to size of CTG repeat expansion. , 1995, JAMA.

[24]  P. Gunby.  Thomas Cole, MD, Is 15th JAMA Fishbein Fellow , 1995 .

[25]  D. Housman,et al.  Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues , 1995, The Journal of cell biology.

[26]  L. Calò,et al.  Cardiac involvement in myotonic dystrophy. , 1994, The American journal of cardiology.

[27]  R. Wevers,et al.  Deficiency of Na+/K(+)-ATPase and sarcoplasmic reticulum Ca(2+)-ATPase in skeletal muscle and cultured muscle cells of myotonic dystrophy patients. , 1993, The Biochemical journal.

[28]  T. Ashizawa,et al.  An unstable triplet repeat in a gene related to myotonic muscular dystrophy. , 1992, Science.

[29]  C. Amemiya,et al.  Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene. , 1992, Science.

[30]  David E. Housman,et al.  Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member , 1992, Cell.

[31]  David E. Housman,et al.  Expansion of an unstable DNA region and phenotypic variation in myotonic dystrophy , 1992, Nature.

[32]  P. Jong,et al.  Detection of an unstable fragment of DNA specific to individuals with myotonic dystrophy , 1992, Nature.

[33]  W. Kingston.  Myotonic Dystrophy, 2nd Ed. , 1990, Neurology.

[34]  E. Nanba,et al.  [Myotonic dystrophy]. , 2005, Nihon rinsho. Japanese journal of clinical medicine.