Synthesis of deuterium-labelled elliptinium and its use in metabolic studies.
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[1] C. Paoletti,et al. Antitumor activity, pharmacology, and toxicity of ellipticines, ellipticinium, and 9-hydroxy derivatives: preliminary clinical trials of 2-methyl-9-hydroxy ellipticinium (NSC 264-137). , 1980, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
[2] C. Paoletti,et al. Unexpected regiospecific alkylation of the antitumor agent N2-methyl-9-hydroxyellipticinium acetate with N, O or S donors , 1983 .
[3] W. Vandenheuvel. Drug Metabolite Identification: Stable Isotope Methods , 1986, Journal of clinical pharmacology.
[4] F. Cavalli,et al. Phase II study of 9-hydroxy-2N-methylellipticinium acetate. , 1984, European Journal of Cancer and Clinical Oncology.
[5] M. Maftouh,et al. Metabolism of the anti-tumour drugs N2-methyl-9-hydroxyellipticinium acetate (NSC 264137) and N2-methyl-9-hydroxyolivacinium acetate in the rat: preliminary identification of biliary 9-(O)-glucuronide and 10-(S)-glutathione conjugates. , 1983, Xenobiotica; the fate of foreign compounds in biological systems.
[6] M. Maftouh,et al. Identification of the glucuronide and glutathione conjugates of the antitumor drug N2-methyl-9-hydroxyellipticinium acetate (Celiptium). Comparative disposition of this drug with its olivacinium isomer in rat bile. , 1984, Drug metabolism and disposition: the biological fate of chemicals.
[7] C. Paoletti,et al. A revised structure of the antitumor drug elliptinium--amino(acid) adducts. , 1985, Biochemical and biophysical research communications.
[8] T. Baillie,et al. Recent Advances in the Use of Stable Isotopes in Drug Metabolism Research , 1986, Journal of clinical pharmacology.
[9] J. Droz,et al. Pharmacokinetics of 2-methyl-9-hydroxyellipticinium acetate (NSC-264137) in cancer patients (phase I study). , 1982, European journal of cancer & clinical oncology.
[10] J. van der Greef,et al. Determination of progesterone by liquid chromatography-mass spectrometry using a moving-belt interface and isotope dilution. , 1985, Journal of chromatography.