Modeling the temperature dependence of thermophysical properties: Study on the effect of temperature dependence for RFA

Radio frequency ablation (RFA) has increasingly been used over the past few years and RFA treatment is minimally invasive for patients. However, it is difficult for operators to control the precise formation of coagulation zones due to inadequate imaging modalities. With this in mind, an ablation system using numerical simulation to analyze the temperature distribution of the organ is needed to overcome this deficiency. The objective of our work is to develop a temperature dependent thermophysical liver model. First, an overview is given of the development of the thermophysical liver model. Second, a simulation to evaluate the effect of temperature dependence of the thermophysical properties of the liver is explained. Finally, the result of the simulation, which indicated that the temperature dependence of thermophysical properties accounts for temperature differences influencing the accuracy of RFA treatment is described.

[1]  A. Eriksson,et al.  Influence of electrical and thermal properties on RF ablation of breast cancer: is the tumour preferentially heated? , 2005, Biomedical engineering online.

[2]  Isaac Chang,et al.  Finite Element Analysis of Hepatic Radiofrequency Ablation Probes using Temperature-Dependent Electrical Conductivity , 2003, Biomedical engineering online.

[3]  John G. Webster,et al.  Measurement and Analysis of Tissue Temperature During Microwave Liver Ablation , 2007, IEEE Transactions on Biomedical Engineering.

[4]  G. Marrocco,et al.  Time-dependent microwave radiometry for the measurement of temperature in medical applications , 2004, IEEE Transactions on Microwave Theory and Techniques.

[5]  H. H. Pennes.  Analysis of tissue and arterial blood temperatures in the resting human forearm. 1948. , 1948, Journal of applied physiology.

[6]  Russell H. Taylor,et al.  Medical robotics in computer-integrated surgery , 2003, IEEE Trans. Robotics Autom..

[7]  Li Su,et al.  Computer-aided dynamic simulation of microwave-induced thermal distribution in coagulation of liver cancer , 2001, IEEE Trans. Biomed. Eng..

[8]  Jun Okamoto,et al.  Physical Properties of the Liver and the Development of an Intelligent Manipulator for Needle Insertion , 2005, Proceedings of the 2005 IEEE International Conference on Robotics and Automation.

[9]  Jonathan W. Valvano,et al.  Thermal conductivity and diffusivity of biomaterials measured with self-heated thermistors , 1985 .

[10]  O. Fujiwara,et al.  FDTD-derived correlation of maximum temperature increase and peak SAR in child and adult head models due to dipole antenna , 2006, IEEE Transactions on Electromagnetic Compatibility.

[11]  Uyen D. Nguyen,et al.  Thermal modeling of lesion growth with radiofrequency ablation devices , 2004, Biomedical engineering online.

[12]  M. Fujie,et al.  Viscoelastic and Nonlinear Organ Model for Control of Needle Insertion Manipulator , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[13]  Masakatsu G. Fujie,et al.  Deformation simulation using a viscoelastic and nonlinear Organ model for control of a needle insertion manipulator , 2007, 2007 IEEE/RSJ International Conference on Intelligent Robots and Systems.

[14]  P. Wolf,et al.  A Three-Dimensional Finite Element Model of Radiofrequency Ablation with Blood Flow and its Experimental Validation , 2000, Annals of Biomedical Engineering.

[15]  Yilong Lu,et al.  Electromagnetic and thermal simulations of 3-D human head model under RF radiation by using the FDTD and FD approaches , 1996 .

[16]  Y. Kobayashi,et al.  Modeling the temperature dependence of thermal conductivity: Developing a system for robot-assisted RFA therapy , 2008, 2008 2nd IEEE RAS & EMBS International Conference on Biomedical Robotics and Biomechatronics.

[17]  Blake Hannaford,et al.  Smart surgical tools and augmenting devices , 2003, IEEE Trans. Robotics Autom..

[18]  A. Hirata,et al.  Temperature increase in the human head due to a dipole antenna at microwave frequencies , 2003 .

[19]  I. Tanasawa,et al.  Genuine and pseudo-thermophysical properties of biological media , 1984 .

[20]  Jun Okamoto,et al.  Physical properties of the liver for needle insertion control , 2004, 2004 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (IEEE Cat. No.04CH37566).

[21]  Hong Cao,et al.  Three-dimensional finite-element analyses for radio-frequency hepatic tumor ablation , 2002, IEEE Trans. Biomed. Eng..

[22]  F. Duck.  Physical properties of tissue , 1990 .

[23]  H. H. Penns.  Analysis of tissue and arterial blood temperatures in the resting human forearm , 1948 .

[24]  John G. Webster,et al.  Finite-element analysis of hepatic multiple probe radio-frequency ablation , 2002, IEEE Transactions on Biomedical Engineering.