RETRACTED ARTICLE: The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA

[1]  A. Jemal,et al.  Cancer statistics, 2022 , 2022, CA: a cancer journal for clinicians.

[2]  Dan Xu,et al.  USP39 promotes malignant proliferation and angiogenesis of renal cell carcinoma by inhibiting VEGF-A165b alternative splicing via regulating SRSF1 and SRPK1 , 2021, Cancer Cell International.

[3]  M. Reese,et al.  Small extracellular vesicle non-coding RNAs in pancreatic cancer: molecular mechanisms and clinical implications , 2021, Journal of Hematology & Oncology.

[4]  R. Sebra,et al.  Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer , 2021, Gut.

[5]  Yingyan Yu,et al.  Dexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways , 2021, Oncogene.

[6]  Xinying Li,et al.  The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor , 2021, Frontiers in Oncology.

[7]  Xiangkai Li,et al.  NAT10 promotes gastric cancer metastasis via N4-acetylated COL5A1 , 2021, Signal Transduction and Targeted Therapy.

[8]  A. Aravanis,et al.  A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection , 2021, Nature Communications.

[9]  Yun Wang,et al.  MYC-Activated LncRNA MNX1-AS1 Promotes the Progression of Colorectal Cancer by Stabilizing YB1 , 2021, Cancer Research.

[10]  Haiyang Guo,et al.  Splicing factor USP39 promotes ovarian cancer malignancy through maintaining efficient splicing of oncogenic HMGA2 , 2021, Cell Death & Disease.

[11]  Baofeng Yu,et al.  Higher postoperative plasma EV PD-L1 predicts poor survival in patients with gastric cancer , 2021, Journal for ImmunoTherapy of Cancer.

[12]  M. Falasca,et al.  Invited mini review article for the special Issue:lncRNA_precision medicine exosomal long non-coding RNAs in the diagnosis and oncogenesis of pancreatic cancer. , 2020, Cancer letters.

[13]  Maite Huarte,et al.  Gene regulation by long non-coding RNAs and its biological functions , 2020, Nature reviews. Molecular cell biology.

[14]  P. Sun,et al.  Ubiquitin‐specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation , 2020, Molecular oncology.

[15]  N. Malats,et al.  A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case–control study , 2020, PLoS medicine.

[16]  B. Kuehn Looking to Long-term Survivors for Improved Pancreatic Cancer Treatment. , 2020, JAMA.

[17]  Hongyang Zhao,et al.  Hypoxic Glioma Stem Cell–Derived Exosomes Containing Linc01060 Promote Progression of Glioma by Regulating the MZF1/c-Myc/HIF1α Axis , 2020, Cancer Research.

[18]  M. Katz,et al.  DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis , 2020, bioRxiv.

[19]  H. Xi,et al.  Circulating Exosomal Gastric Cancer–Associated Long Noncoding RNA1 as a Biomarker for Early Detection and Monitoring Progression of Gastric Cancer , 2020, JAMA surgery.

[20]  Qiaojun He,et al.  USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ , 2020, Cancer Research.

[21]  D. Lin,et al.  Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming , 2020, Nature Communications.

[22]  Xin Hu,et al.  Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer , 2020, Nucleic acids research.

[23]  B. Wang,et al.  LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes , 2020, Aging.

[24]  Proteasome , 2020, Definitions.

[25]  Hao-Jie Lu,et al.  BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma , 2020, Nature Cell Biology.

[26]  D. Lin,et al.  Long Noncoding RNA p53‐Stabilizing and Activating RNA Promotes p53 Signaling by Inhibiting Heterogeneous Nuclear Ribonucleoprotein K deSUMOylation and Suppresses Hepatocellular Carcinoma , 2020, Hepatology.

[27]  Tianxin Lin,et al.  Exosomal long noncoding RNA LNMAT2 promotes lymphatic metastasis in bladder cancer. , 2019, The Journal of clinical investigation.

[28]  Z. Wang,et al.  Plasma extracellular vesicle long RNA profiling identifies a diagnostic signature for the detection of pancreatic ductal adenocarcinoma , 2019, Gut.

[29]  Youwei Zhu,et al.  TET1-mediated DNA hydroxymethylation activates inhibitors of the Wnt/β-catenin signaling pathway to suppress EMT in pancreatic tumor cells , 2019, Journal of Experimental & Clinical Cancer Research.

[30]  Eugene J Koay,et al.  Early Detection of Pancreatic Cancer: Opportunities and Challenges. , 2019, Gastroenterology.

[31]  Yang Wang,et al.  Cellular functions of long noncoding RNAs , 2019, Nature Cell Biology.

[32]  Lei Zhan,et al.  LAMB3 mediates apoptotic, proliferative, invasive, and metastatic behaviors in pancreatic cancer by regulating the PI3K/Akt signaling pathway , 2019, Cell Death & Disease.

[33]  Shou-Jiang Gao,et al.  A DHX9-lncRNA-MDM2 interaction regulates cell invasion and angiogenesis of cervical cancer , 2018, Cell Death & Differentiation.

[34]  David Sturgill,et al.  Acetylation of Cytidine in mRNA Promotes Translation Efficiency , 2018, Cell.

[35]  Gideon Rechavi,et al.  N 4-acetylation of Cytidine in mRNA by NAT10 Regulates Stability and Translation , 2018, Cell.

[36]  Chen Huang,et al.  Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer Metastasis. , 2018, Cancer research.

[37]  Li Yang,et al.  Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer , 2018, Molecular Cancer.

[38]  Di Chen,et al.  The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma , 2018, Nature Communications.

[39]  Y. Zhang,et al.  Exosomal long noncoding RNA HOTTIP as potential novel diagnostic and prognostic biomarker test for gastric cancer , 2018, Molecular Cancer.

[40]  Graça Raposo,et al.  Shedding light on the cell biology of extracellular vesicles , 2018, Nature Reviews Molecular Cell Biology.

[41]  Bing Chen,et al.  exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes , 2017, Nucleic Acids Res..

[42]  Tao Pan,et al.  Dynamic RNA Modifications in Gene Expression Regulation , 2017, Cell.

[43]  Hakho Lee,et al.  Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy , 2017, Science Translational Medicine.

[44]  Ge Gao,et al.  CPC2: a fast and accurate coding potential calculator based on sequence intrinsic features , 2017, Nucleic Acids Res..

[45]  Samir Adhikari,et al.  5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C reader , 2017, Cell Research.

[46]  S. Lowe,et al.  USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer* , 2017, The Journal of Biological Chemistry.

[47]  J. Beermann,et al.  Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches. , 2016, Physiological reviews.

[48]  Tian-Tian Sun,et al.  LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern. , 2016, Cancer discovery.

[49]  Jin Ding,et al.  Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA. , 2016, Cancer cell.

[50]  Clotilde Théry,et al.  Communication by Extracellular Vesicles: Where We Are and Where We Need to Go , 2016, Cell.

[51]  Jianyuan Luo,et al.  NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2 , 2016, EMBO reports.

[52]  Fei Wang,et al.  Transcriptome-wide distribution and function of RNA hydroxymethylcytosine , 2016, Science.

[53]  Howard Y. Chang,et al.  Unique features of long non-coding RNA biogenesis and function , 2015, Nature Reviews Genetics.

[54]  Maite Huarte The emerging role of lncRNAs in cancer , 2015, Nature Medicine.

[55]  R. Brekken,et al.  Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis. , 2015, Cancer research.

[56]  Christian Pilarsky,et al.  Glypican-1 identifies cancer exosomes and detects early pancreatic cancer , 2015, Nature.

[57]  K. Entian,et al.  Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1 , 2015, Nucleic acids research.

[58]  Tsutomu Suzuki,et al.  Human NAT10 Is an ATP-dependent RNA Acetyltransferase Responsible for N4-Acetylcytidine Formation in 18 S Ribosomal RNA (rRNA)* , 2014, The Journal of Biological Chemistry.

[59]  J. Rinn,et al.  Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination , 2013, Nature Communications.

[60]  H. Cline,et al.  Exosomes function in cell–cell communication during brain circuit development , 2013, Current Opinion in Neurobiology.

[61]  J. Kocher,et al.  CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model , 2013, Nucleic acids research.

[62]  S. Wickline,et al.  Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis. , 2011, Cancer research.

[63]  Howard Y. Chang,et al.  Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes , 2010, Science.

[64]  J. Rinn,et al.  A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response , 2010, Cell.

[65]  Howard Y. Chang,et al.  Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasis , 2010, Nature.

[66]  Jennifer A. Mitchell,et al.  The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin , 2008, Science.

[67]  Rrio Op-amps FEATURES , 2008 .

[68]  B. Monia,et al.  Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice , 2005, Hepatology.

[69]  J. Wyatt,et al.  Study , 2022, Evaluation Methods in Biomedical and Health Informatics.

[70]  E. Diamandis,et al.  Pancreatic cancer. , 2013, Clinical chemistry.

[71]  Aaron Ciechanover,et al.  Proteolysis: from the lysosome to ubiquitin and the proteasome , 2005, Nature Reviews Molecular Cell Biology.

[72]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[73]  A. Chávez-Reyes,et al.  International Journal of Molecular Sciences Exosomes: from Garbage Bins to Promising Therapeutic Targets , 2022 .