Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors.

[1]  M. Adams,et al.  CALCIUM CHANNEL DIVERSITY AND NEUROTRANSMITTER RELEASE : THE OMEGA -CONOTOXINS AND OMEGA -AGATOXINS , 1994 .

[2]  S. Aaronson,et al.  A small v-sis/platelet-derived growth factor (PDGF) B-protein domain in which subtle conformational changes abrogate PDGF receptor interaction and transforming activity , 1990, Molecular and cellular biology.

[3]  A. H. Drummond,et al.  Two PDGF‐B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation. , 1991, The EMBO journal.

[4]  T. Blundell,et al.  Nerve growth factor revisited. , 1993, Trends in biochemical sciences.

[5]  Joseph Schlessinger,et al.  Signal transduction by receptors with tyrosine kinase activity , 1990, Cell.

[6]  J Murray-Rust,et al.  An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan‐neurotrophin. , 1993, The EMBO journal.

[7]  R. Bradshaw,et al.  The receptors for nerve growth factor and other neurotrophins. , 1993, Annual review of biochemistry.

[8]  C. Heldin,et al.  Structural and functional studies on platelet‐derived growth factor. , 1992, The EMBO journal.

[9]  L. Chiche,et al.  Molecular recognition between serine proteases and new bioactive microproteins with a knotted structure. , 1990, Biochimie.

[10]  D. Davies,et al.  Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily. , 1992, Science.

[11]  J. Lile,et al.  GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. , 1993, Science.

[12]  P. Bork.  The modular architecture of a new family of growth regulators related to connective tissue growth factor , 1993, FEBS letters.

[13]  M. Sporn,et al.  Transforming growth factor beta 1: NMR signal assignments of the recombinant protein expressed and isotopically enriched using Chinese hamster ovary cells. , 1993, Biochemistry.

[14]  M. Grütter,et al.  An unusual feature revealed by the crystal structure at 2.2 Å resolution of human transforming growth fact or-β2 , 1992, Nature.

[15]  D C Rees,et al.  Refined crystal structure of the potato inhibitor complex of carboxypeptidase A at 2.5 A resolution. , 1982, Journal of molecular biology.

[16]  S V Evans,et al.  SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. , 1993, Journal of molecular graphics.

[17]  T L Blundell,et al.  A variable gap penalty function and feature weights for protein 3-D structure comparisons. , 1992, Protein engineering.

[18]  C. Heldin,et al.  Identification of a peptide antagonist for platelet-derived growth factor. , 1992, The Journal of biological chemistry.

[19]  T. Ebendal.  Function and evolution in the NGF family and its receptors , 1992, Journal of neuroscience research.

[20]  J. Massagué,et al.  The transforming growth factor-beta family. , 1990, Annual review of cell biology.

[21]  R. Weinberg,et al.  Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase , 1992, Cell.

[22]  U. Hellman,et al.  Identification of three amino acids in the platelet-derived growth factor (PDGF) B-chain that are important for binding to the PDGF beta-receptor. , 1991, The Journal of biological chemistry.

[23]  J. Massagué.  Receptors for the TGF-β family , 1992, Cell.

[24]  M. Swindells.  Structural similarity between transforming growth factor-beta 2 and nerve growth factor. , 1992, Science.

[25]  Tom L. Blundell,et al.  New protein fold revealed by a 2.3-Å resolution crystal structure of nerve growth factor , 1991, Nature.

[26]  M. Chao.  Neurotrophin receptors: A window into neuronal differentiation , 1992, Neuron.

[27]  M. Grütter,et al.  Refined Crystal Structure of Human Transforming Growth Factor β2 at 1·5 Å Resolution , 1993 .

[28]  W. Hendrickson,et al.  A structural superfamily of growth factors containing a cystine knot motif , 1993, Cell.

[29]  C. Chothia,et al.  Protein architecture: New superfamilies , 1992, Current Biology.

[30]  C. Ibáñez,et al.  Chimeric molecules with multiple neurotrophic activities reveal structural elements determining the specificities of NGF and BDNF. , 1991, The EMBO journal.

[31]  R. Sowdhamini,et al.  Conformations of disulfide bridges in proteins. , 2009, International journal of peptide and protein research.

[32]  Tom L. Blundell,et al.  Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product , 1992, Cell.

[33]  C. Ibáñez,et al.  Structure‐function studies of nerve growth factor: functional importance of highly conserved amino acid residues. , 1990, The EMBO journal.

[34]  F. Winkler,et al.  Crystal structure of human platelet‐derived growth factor BB. , 1992, The EMBO journal.

[35]  U. Hellman,et al.  Assignment of interchain disulfide bonds in platelet-derived growth factor (PDGF) and evidence for agonist activity of monomeric PDGF. , 1992, The Journal of biological chemistry.

[36]  T. Blundell,et al.  Definition of general topological equivalence in protein structures. A procedure involving comparison of properties and relationships through simulated annealing and dynamic programming. , 1990, Journal of molecular biology.

[37]  H. Lodish,et al.  Receptors for the TGF-beta superfamily: multiple polypeptides and serine/threonine kinases. , 1993, Trends in cell biology.

[38]  L. Butcher,et al.  Induction of apoptosis by the low-affinity NGF receptor. , 1993, Science.