The anti‐inflammatory mechanism of 635 nm light‐emitting‐diode irradiation compared with existing COX inhibitors

Inhibition of cyclooxygenase (COX) and prostaglandin E2 (PGE2) protects cells against cell injury in specific pathophysiological situations: inflammation and oxidative stress. Although the anti‐inflammatory effects have been reported in clinical fields for specific wavelength irradiation during wound healing, the physiological mechanism has not been clarified yet. The aim of the present study is to investigate the anti‐inflammatory mechanism of 635 nm light‐emitting‐diode (LED) irradiation compared with existing COX inhibitors.

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