Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells.

[1]  I. Fuss,et al.  Induction of TNBS colitis in mice. , 2002, Current protocols in immunology.

[2]  L. Teyton,et al.  Distinct Functional Lineages of Human Vα24 Natural Killer T Cells , 2002, The Journal of experimental medicine.

[3]  M. Leach,et al.  IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. , 2001, Immunity.

[4]  T. Yamamura,et al.  A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells , 2001, Nature.

[5]  Jay A. Berzofsky,et al.  NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway , 2000, Nature Immunology.

[6]  S. Porcelli,et al.  Low expression level but potent antigen presenting function of CD1d on monocyte lineage cells , 2000, European journal of immunology.

[7]  L. Bockenstedt,et al.  Cutting Edge: CD1d Deficiency Impairs Murine Host Defense Against the Spirochete, Borrelia burgdorferi1 , 2000, The Journal of Immunology.

[8]  D. McKay,et al.  Interleukins 4 and 13 Increase Intestinal Epithelial Permeability by a Phosphatidylinositol 3-Kinase Pathway , 2000, The Journal of Biological Chemistry.

[9]  M. Taniguchi,et al.  CD4(+) v(alpha)14 NKT cells play a crucial role in an early stage of protective immunity against infection with Leishmania major. , 2000, International immunology.

[10]  S. Snapper,et al.  Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice. , 2000, Gastroenterology.

[11]  L. Kaer,et al.  Critical contribution of liver natural killer T cells to a murine model of hepatitis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[12]  L. Lefrançois,et al.  Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction. , 2000, Immunity.

[13]  S. Porcelli,et al.  Murine CD1d-restricted T cell recognition of cellular lipids. , 2000, Immunity.

[14]  M. Taniguchi,et al.  Augmentation of Vα14 Nkt Cell–Mediated Cytotoxicity by Interleukin 4 in an Autocrine Mechanism Resulting in the Development of Concanavalin a–Induced Hepatitis , 2000, The Journal of experimental medicine.

[15]  S. Snapper,et al.  Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site , 1999, The Journal of experimental medicine.

[16]  A. Herbelin,et al.  IL-7 up-regulates IL-4 production by splenic NK1.1+ and NK1.1- MHC class I-like/CD1-dependent CD4+ T cells. , 1999, Journal of immunology.

[17]  E. Mizoguchi,et al.  The critical role of interleukin 4 but not interferon gamma in the pathogenesis of colitis in T-cell receptor alpha mutant mice. , 1999, Gastroenterology.

[18]  D B Corry,et al.  Requirement for IL-13 independently of IL-4 in experimental asthma. , 1998, Science.

[19]  D D Donaldson,et al.  Interleukin-13: central mediator of allergic asthma , 1998 .

[20]  W. Strober,et al.  Oxazolone Colitis: A Murine Model of  T Helper Cell Type 2 Colitis Treatable with Antibodies to Interleukin 4 , 1998, The Journal of experimental medicine.

[21]  S. Porcelli,et al.  CD1d-restricted Recognition of Synthetic Glycolipid Antigens by Human Natural Killer T Cells , 1998, The Journal of experimental medicine.

[22]  D D Donaldson,et al.  The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1. , 1998, Journal of immunology.

[23]  H. Macdonald,et al.  Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice , 1998 .

[24]  U. Kavita,et al.  CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells. , 1998, Journal of immunology.

[25]  S. Park,et al.  Tissue-specific recognition of mouse CD1 molecules. , 1998, Journal of immunology.

[26]  F. Finkelman,et al.  IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. , 1998, Immunity.

[27]  Hiroshi Sato,et al.  CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. , 1997, Science.

[28]  Hiroshi Sato,et al.  Requirement for Vα14 NKT Cells in IL-12-Mediated Rejection of Tumors , 1997 .

[29]  A. Minty,et al.  The related cytokines interleukin-13 and interleukin-4 are distinguished by differential production and differential effects on T lymphocytes. , 1997, European cytokine network.

[30]  W. Paul,et al.  Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN-gamma upon activation by anti-CD3 or CD1. , 1997, Journal of immunology.

[31]  F. Annunziato,et al.  Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. , 1997, The American journal of pathology.

[32]  M. Kaplan,et al.  Immunoglobulin E Production in the Absence of Interleukin-4-Secreting CD1-Dependent Cells , 1997, Science.

[33]  K. Rogers,et al.  Beta 2-microglobulin-dependent T cells are dispensable for allergen- induced T helper 2 responses , 1996, The Journal of experimental medicine.

[34]  M. Neurath,et al.  Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. , 1996, Journal of immunology.

[35]  S. Strober,et al.  Double Negative (CD4−CD8−αβ+) T Cells Which Promote Tolerance Induction and Regulate Autoimmunity , 1996, Immunological reviews.

[36]  A. Bendelac Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes , 1995, The Journal of experimental medicine.

[37]  M. Neurath,et al.  Antibodies to interleukin 12 abrogate established experimental colitis in mice , 1995, The Journal of experimental medicine.

[38]  R. Sartor Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease. , 1995, Gastroenterology clinics of North America.

[39]  O. Lantz,et al.  An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans , 1994, The Journal of experimental medicine.

[40]  S. Koyasu,et al.  CD3+CD16+NK1.1+B220+ large granular lymphocytes arise from both alpha- beta TCR+CD4-CD8- and gamma-delta TCR+CD4-CD8- cells , 1994, The Journal of experimental medicine.

[41]  W. Paul,et al.  CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3 , 1994, The Journal of experimental medicine.

[42]  R. Hardy,et al.  Murine thymic CD4+ T cell subsets: a subset (Thy0) that secretes diverse cytokines and overexpresses the V beta 8 T cell receptor gene family , 1992, The Journal of experimental medicine.

[43]  S. Balk,et al.  Expression of a nonpolymorphic MHC class I-like molecule, CD1D, by human intestinal epithelial cells. , 1991, Journal of immunology.

[44]  T. Mosmann,et al.  IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. , 1991, Journal of immunology.

[45]  T. Flotte,et al.  Expression of murine CD1 on gastrointestinal epithelium. , 1990, Science.

[46]  J. D. de Vries,et al.  Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. , 1994, Immunology today.

[47]  C. Terhorst,et al.  Isolation and characterization of a cDNA and gene coding for a fourth CD1 molecule. , 1989, Proceedings of the National Academy of Sciences of the United States of America.