Establishment of a human three-dimensional chip-based chondro-synovial coculture joint model for reciprocal cross talk studies in arthritis research.
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P. Ertl | R. Byrne | S. Toegel | W. Holnthoner | H. Redl | R. Windhager | H. Kiener | M. Rothbauer | F. Sevelda | J. Holinka | I. Olmos Calvo | S. Spitz | B. Bachmann | A. Fischer | E. I. Reihs | S. Schobesberger
[1] T. Hughes,et al. The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. , 2021, Immunity.
[2] P. Ertl,et al. An on-chip wound healing assay fabricated by xurography for evaluation of dermal fibroblast cell migration and wound closure , 2020, Scientific Reports.
[3] P. Ertl,et al. Stiffness Matters: Fine-Tuned Hydrogel Elasticity Alters Chondrogenic Redifferentiation , 2020, Frontiers in Bioengineering and Biotechnology.
[4] N. Hacohen,et al. Notch signaling drives synovial fibroblast identity and arthritis pathology , 2020, Nature.
[5] A. Gyenesei,et al. Microfluidic nutrient gradient–based three-dimensional chondrocyte culture-on-a-chip as an in vitro equine arthritis model , 2019, Materials today. Bio.
[6] G. Superti-Furga,et al. IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes , 2019, Experimental & Molecular Medicine.
[7] P. Ertl,et al. Characterization of four functional biocompatible pressure-sensitive adhesives for rapid prototyping of cell-based lab-on-a-chip and organ-on-a-chip systems , 2019, Scientific Reports.
[8] S. Toegel,et al. Galectins‐1 and ‐3 in Human Intervertebral Disc Degeneration: Non‐Uniform Distribution Profiles and Activation of Disease Markers Involving NF‐κB by Galectin‐1 , 2019, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[9] S. Raychaudhuri,et al. Distinct fibroblast subsets drive inflammation and damage in arthritis , 2019, Nature.
[10] P. Ertl,et al. Effect of Spheroidal Age on Sorafenib Diffusivity and Toxicity in a 3D HepG2 Spheroid Model , 2019, Scientific Reports.
[11] S. Peh,et al. Pathogenic Role of Immune Cells in Rheumatoid Arthritis: Implications in Clinical Treatment and Biomarker Development , 2018, Cells.
[12] Ting Zhao,et al. A microfluidic chip-based co-culture of fibroblast-like synoviocytes with osteoblasts and osteoclasts to test bone erosion and drug evaluation , 2018, Royal Society Open Science.
[13] P. Ertl,et al. Engineering of three-dimensional pre-vascular networks within fibrin hydrogel constructs by microfluidic control over reciprocal cell signaling. , 2018, Biomicrofluidics.
[14] N. Hacohen,et al. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry , 2018, bioRxiv.
[15] S. Monrad,et al. Early Diagnosis and Treatment of Rheumatoid Arthritis. , 2018, Primary care.
[16] Dongan Wang,et al. Establishment of an in vitro three‐dimensional model for cartilage damage in rheumatoid arthritis , 2018, Journal of tissue engineering and regenerative medicine.
[17] T. Takeuchi,et al. Targeted antibody therapy and relevant novel biomarkers for precision medicine for rheumatoid arthritis , 2017, International immunology.
[18] David J Mooney,et al. Mechanical confinement regulates cartilage matrix formation by chondrocytes , 2017, Nature materials.
[19] G. Burmester,et al. Novel treatment strategies in rheumatoid arthritis , 2017, The Lancet.
[20] D. Fox,et al. Synovial cellular and molecular markers in rheumatoid arthritis , 2017, Seminars in Immunopathology.
[21] Toshio Tanaka,et al. The role and therapeutic targeting of IL-6 in rheumatoid arthritis , 2017, Expert review of clinical immunology.
[22] A. Griffioen,et al. Targeting non-canonical nuclear factor-&kgr;B signalling attenuates neovascularization in a novel 3D model of rheumatoid arthritis synovial angiogenesis , 2017, Rheumatology.
[23] A. Mantovani,et al. Macrophage heterogeneity in the context of rheumatoid arthritis , 2016, Nature Reviews Rheumatology.
[24] P. Taylor,et al. A structured literature review of the burden of illness and unmet needs in patients with rheumatoid arthritis: a current perspective , 2016, Rheumatology International.
[25] Yoshiya Tanaka,et al. Contribution of the Interleukin‐6/STAT‐3 Signaling Pathway to Chondrogenic Differentiation of Human Mesenchymal Stem Cells , 2015, Arthritis & rheumatology.
[26] R. Caporali,et al. B Cells in Rheumatoid Arthritis: From Pathogenic Players to Disease Biomarkers , 2014, BioMed research international.
[27] R. J. Baatenburg de Jong,et al. Effects of transforming growth factor‐β subtypes on in vitro cartilage production and mineralization of human bone marrow stromal‐derived mesenchymal stem cells , 2012, Journal of tissue engineering and regenerative medicine.
[28] A. Silman,et al. UvA-DARE (Digital Academic Repository) 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative Aletaha, , 2010 .
[29] A. Kimura,et al. IL‐6: Regulator of Treg/Th17 balance , 2010, European journal of immunology.
[30] T. Thornhill,et al. Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture. , 2010, Arthritis and rheumatism.
[31] G. Burmester,et al. Cells of the synovium in rheumatoid arthritis. Macrophages , 2007, Arthritis research & therapy.
[32] F. Pampaloni,et al. The third dimension bridges the gap between cell culture and live tissue , 2007, Nature Reviews Molecular Cell Biology.
[33] A. Facchini,et al. VEGF Production by Osteoarthritic Chondrocytes Cultured in Micromass and Stimulated by IL-17 and TNF-α , 2007, Connective tissue research.
[34] M. Brenner,et al. Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro. , 2006, The American journal of pathology.
[35] A. Facchini,et al. IL-17, IL-1β and TNF-α stimulate VEGF production by dedifferentiated chondrocytes , 2004 .
[36] W. B. van den Berg,et al. Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering. , 2002, Osteoarthritis and cartilage.
[37] Denis Vivien,et al. Differential effects of transforming growth factor‐β and epidermal growth factor on the cell cycle of cultured rabbit articular chondrocytes , 1990, Journal of cellular physiology.
[38] R. Thurlings,et al. A three-dimensional model to study human synovial pathology. , 2019, ALTEX.