Selection of antibodies from synthetic antibody libraries.
暂无分享,去创建一个
[1] G. P. Smith,et al. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. , 1985, Science.
[2] I Berger,et al. In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[3] G. Winter,et al. Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain. , 1996, Journal of molecular biology.
[4] K. D. Hardman,et al. Single-chain antigen-binding proteins. , 1988, Science.
[5] Jamshid Tanha,et al. Selection by phage display of llama conventional V(H) fragments with heavy chain antibody V(H)H properties. , 2002, Journal of immunological methods.
[6] Tristan J. Vaughan,et al. Human Antibodies with Sub-nanomolar Affinities Isolated from a Large Non-immunized Phage Display Library , 1996, Nature Biotechnology.
[7] J. Osbourn,et al. From rodent reagents to human therapeutics using antibody guided selection. , 2005, Methods.
[8] L. Jolliffe. Humanized antibodies: enhancing therapeutic utility through antibody engineering. , 1993, International reviews of immunology.
[9] A. Bradbury,et al. Antibodies from phage antibody libraries. , 2004, Journal of immunological methods.
[10] H R Hoogenboom,et al. Antibody phage display technology and its applications. , 1998, Immunotechnology : an international journal of immunological engineering.
[11] P. Hudson,et al. Latest technologies for the enhancement of antibody affinity. , 2006, Advanced drug delivery reviews.
[12] Hennie R. Hoogenboom,et al. Guiding the Selection of Human Antibodies from Phage Display Repertoires to a Single Epitope of an Antigen , 1994, Bio/Technology.
[13] G. Georgiou,et al. Selection of full‐length IgGs by tandem display on filamentous phage particles and Escherichia coli fluorescence‐activated cell sorting screening , 2010, The FEBS journal.
[14] E. Tongiorgi,et al. Molecular Dissection of the Tissue Transglutaminase Autoantibody Response in Celiac Disease1 , 2001, The Journal of Immunology.
[15] Anthony D. Keefe,et al. The use of mRNA display to select high-affinity protein-binding peptides , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[16] J. Marks,et al. Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating. , 2010, Protein engineering, design & selection : PEDS.
[17] G. Georgiou,et al. Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface. , 1999, Protein engineering.
[18] T. Clackson,et al. Phage display : a practical approach , 2004 .
[19] U. Sivan,et al. A two-state electronic antigen and an antibody selected to discriminate between these states. , 2008, Nano letters.
[20] S. Sidhu. Phage display in biotechnology and drug discovery , 2005 .
[21] T. Logtenberg,et al. Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions. , 1995, Journal of molecular biology.
[22] A. Plückthun,et al. Assembly of a functional immunoglobulin Fv fragment in Escherichia coli. , 1988, Science.
[23] L. Riechmann,et al. A conserved infection pathway for filamentous bacteriophages is suggested by the structure of the membrane penetration domain of the minor coat protein g3p from phage fd. , 1997, Structure.
[24] H. Steven Wiley,et al. Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library , 2003, Nature Biotechnology.
[25] J. Gerhart,et al. Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[26] E. Padlan,et al. A possible procedure for reducing the immunogenicity of antibody variable domains while preserving their ligand-binding properties. , 1991, Molecular immunology.
[27] D R Burton,et al. In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[28] C. Barbas,et al. Phage display of combinatorial antibody libraries. , 1997, Current opinion in biotechnology.
[29] Müller Kristian,et al. Protein Engineering Protocols , 2006, Methods in Molecular Biology™.
[30] A. Plückthun,et al. Tailoring in vitro evolution for protein affinity or stability. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[31] G. G. Stokes. "J." , 1890, The New Yale Book of Quotations.
[32] Viktor Stein,et al. New genotype-phenotype linkages for directed evolution of functional proteins. , 2005, Current opinion in structural biology.
[33] H R Hoogenboom,et al. Designing and optimizing library selection strategies for generating high-affinity antibodies. , 1997, Trends in biotechnology.
[34] E. Söderlind,et al. Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework. , 1998, Gene.
[35] Sachdev S Sidhu,et al. Synthetic therapeutic antibodies , 2006, Nature chemical biology.
[36] H. Hoogenboom,et al. Selecting and screening recombinant antibody libraries , 2005, Nature Biotechnology.
[37] C. Broder,et al. UvA-DARE ( Digital Academic Repository ) Neutralizing antibodies to the HIV-1 envelope glycoproteins , 2009 .
[38] Eric T. Boder,et al. Yeast surface display for screening combinatorial polypeptide libraries , 1997, Nature Biotechnology.
[39] Herren Wu,et al. Antibody humanization by framework shuffling. , 2005, Methods.
[40] G. Winter,et al. Phage antibodies: filamentous phage displaying antibody variable domains , 1990, Nature.
[41] Jane Wilton,et al. The remarkable flexibility of the human antibody repertoire; isolation of over one thousand different antibodies to a single protein, BLyS. , 2003, Journal of molecular biology.
[42] J. Tanha,et al. Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric points. , 2008, Protein engineering, design & selection : PEDS.
[43] H R Hoogenboom,et al. Natural and designer binding sites made by phage display technology. , 2000, Immunology today.
[44] M. Sheng,et al. Antibodies in haystacks: how selection strategy influences the outcome of selection from molecular diversity libraries. , 2001, Journal of immunological methods.
[45] Miss A.O. Penney. (b) , 1974, The New Yale Book of Quotations.
[46] Farid Khan,et al. Ribosome display: next-generation display technologies for production of antibodies in vitro , 2005, Expert review of proteomics.
[47] A. Plückthun,et al. In vitro selection and evolution of functional proteins by using ribosome display. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[48] George Georgiou,et al. Isolation of engineered, full-length antibodies from libraries expressed in Escherichia coli , 2007, Nature Biotechnology.
[49] Andrew D. Griffiths,et al. By–Passing Immunization: Building High Affinity Human Antibodies by Chain Shuffling , 1992, Bio/Technology.
[50] A. Plückthun,et al. Comparison of Escherichia coli and rabbit reticulocyte ribosome display systems , 1999, FEBS letters.
[51] Mitchell Ho,et al. Isolation of anti-CD22 Fv with high affinity by Fv display on human cells. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[52] W. Dower,et al. An in vitro polysome display system for identifying ligands from very large peptide libraries. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[53] A. Lim,et al. Directed evolution of high-affinity antibody mimics using mRNA display. , 2002, Chemistry & biology.
[54] A. Pini,et al. Design and Use of a Phage Display Library , 1998, The Journal of Biological Chemistry.
[55] I. Mian,et al. Structure, function and properties of antibody binding sites. , 1991, Journal of molecular biology.
[56] L. Wyns,et al. Selection and identification of single domain antibody fragments from camel heavy‐chain antibodies , 1997, FEBS letters.
[57] César Milstein,et al. Man-made antibodies , 1991, Nature.
[58] I. Benhar. Biotechnological applications of phage and cell display. , 2001, Biotechnology advances.
[59] H. Hoogenboom. Overview of antibody phage-display technology and its applications. , 2002, Methods in molecular biology.
[60] M. Taussig,et al. Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites. , 1997, Nucleic acids research.
[61] M. Smith,et al. Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA. , 1982, Nucleic acids research.
[62] Christine Yu,et al. Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies , 2008, Cell.
[63] I. Tomlinson,et al. Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents. , 1994, The EMBO journal.
[64] Avital Lev,et al. Selective Targeting of Melanoma and APCs Using a Recombinant Antibody with TCR-Like Specificity Directed Toward a Melanoma Differentiation Antigen 1 , 2003, The Journal of Immunology.
[65] G. Winter,et al. Expression of an antibody Fv fragment in myeloma cells. , 1988, Journal of molecular biology.
[66] H R Hoogenboom,et al. By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro. , 1992, Journal of molecular biology.
[67] A. Honegger,et al. The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies. , 2008, Journal of molecular biology.
[68] Lutz Riechmann,et al. Reshaping human antibodies for therapy , 1988, Nature.
[69] E. H. Cohen,et al. Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity , 2005, Nature Biotechnology.
[70] U. Bornscheuer,et al. Protein Engineering , 2018, Methods in Molecular Biology.
[71] K D Wittrup,et al. Isolation of anti-T cell receptor scFv mutants by yeast surface display. , 1997, Protein engineering.
[72] T. Clackson,et al. In vitro selection from protein and peptide libraries. , 1994, Trends in biotechnology.
[73] M J Corey,et al. High-affinity peptide ligands to prostate-specific antigen identified by polysome selection. , 1997, Biochemical and biophysical research communications.
[74] R. Siegel,et al. Yeast mating for combinatorial Fab library generation and surface display , 2004, FEBS letters.
[75] G. Winter. Synthetic human antibodies and a strategy for protein engineering , 1998, FEBS letters.
[76] L. Jermutus,et al. Combinatorial protein biochemistry for therapeutics and proteomics. , 2004, Current pharmaceutical biotechnology.
[77] R. Siegel. Antibody affinity optimization using yeast cell surface display. , 2009, Methods in molecular biology.
[78] R. Bruccoleri,et al. Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[79] P. T. Jones,et al. Replacing the complementarity-determining regions in a human antibody with those from a mouse , 1986, Nature.
[80] C. Eigenbrot,et al. High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold. , 2004, Journal of molecular biology.
[81] S. Dübel,et al. Phage display vectors for the in vitro generation of human antibody fragments. , 2005, Methods in molecular biology.
[82] A. Plückthun,et al. Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[83] Mitchell Ho,et al. In Vitro Antibody Evolution Targeting Germline Hot Spots to Increase Activity of an Anti-CD22 Immunotoxin* , 2005, Journal of Biological Chemistry.
[84] A. Plückthun,et al. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. , 2000, Journal of molecular biology.
[85] E. Söderlind,et al. Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries , 2000, Nature Biotechnology.
[86] Frederic A. Fellouse,et al. Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions. , 2004, Journal of molecular biology.
[87] G. Georgiou,et al. Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[88] B. Power,et al. Ribosome display for improved biotherapeutic molecules , 2006, Expert opinion on biological therapy.
[89] Sachdev S Sidhu,et al. Molecular recognition by a binary code. , 2005, Journal of molecular biology.
[90] G. Georgiou,et al. The Expression of Recombinant Proteins on the External Surface of Escherichia coli , 1994, Annals of the New York Academy of Sciences.
[91] John McCafferty,et al. Phage display of peptides and proteins : a laboratory manual , 1996 .
[92] Herren Wu,et al. Framework shuffling of antibodies to reduce immunogenicity and manipulate functional and biophysical properties. , 2007, Molecular immunology.
[93] H R Hoogenboom,et al. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. , 1991, Journal of molecular biology.
[94] M. Holmes,et al. “Superhumanized” Antibodies: Reduction of Immunogenic Potential by Complementarity-Determining Region Grafting with Human Germline Sequences: Application to an Anti-CD281 , 2002, The Journal of Immunology.
[95] Daniele Sblattero,et al. Exploiting recombination in single bacteria to make large phage antibody libraries , 2000, Nature Biotechnology.
[96] D. Aird,et al. Secretion-and-capture cell-surface display for selection of target-binding proteins. , 2011, Protein engineering, design & selection : PEDS.
[97] L. Presta,et al. Antibody Humanization Using Monovalent Phage Display* , 1997, The Journal of Biological Chemistry.
[98] S. Urlinger,et al. HuCAL PLATINUM, a synthetic Fab library optimized for sequence diversity and superior performance in mammalian expression systems. , 2011, Journal of molecular biology.
[99] D R Burton,et al. CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range. , 1995, Journal of molecular biology.
[100] Carlos F. Barbas,et al. Phage display: a Laboratory manual , 2014 .
[101] M. Schwab,et al. An engineered IN-1 F(ab) fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing activity. , 2002, Protein engineering.
[102] George Georgiou,et al. Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli-expressed libraries. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[103] S. Dübel,et al. Screening of molecular repertoires by microbial surface display. , 2005, Combinatorial chemistry & high throughput screening.
[104] I. Pastan,et al. Improving antibody affinity by mimicking somatic hypermutation in vitro , 1999, Nature Biotechnology.
[105] Mitchell Ho,et al. Display and selection of scFv antibodies on HEK-293T cells. , 2009, Methods in molecular biology.
[106] Hennie R. Hoogenboom,et al. A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies* , 1999, The Journal of Biological Chemistry.
[107] George Georgiou,et al. Engineering of recombinant antibody fragments to methamphetamine by anchored periplasmic expression. , 2006, Journal of immunological methods.
[108] I. Benhar. Design of synthetic antibody libraries , 2007, Expert opinion on biological therapy.
[109] G. Winter,et al. Improved oligonucleotide site-directed mutagenesis using M13 vectors. , 1985, Nucleic acids research.
[110] A. Wehnert,et al. Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates , 2008, The Journal of Immunology.
[111] Andreas Plückthun,et al. In-vitro protein evolution by ribosome display and mRNA display. , 2004, Journal of immunological methods.
[112] Dirk Ponsel,et al. High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation , 2011, Molecules.
[113] I. Benhar,et al. A human synthetic combinatorial library of arrayable single-chain antibodies based on shuffling in vivo formed CDRs into general framework regions. , 2004, Journal of molecular biology.
[114] P. T. Jones,et al. Isolation of high affinity human antibodies directly from large synthetic repertoires. , 1994, The EMBO journal.
[115] A. Wehnert,et al. Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments. , 2004, Gene.
[116] K. Wittrup,et al. Shuffled antibody libraries created by in vivo homologous recombination and yeast surface display. , 2004, Nucleic acids research.
[117] A. Garen,et al. Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[118] K D Wittrup,et al. Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[119] Qian Wang,et al. Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4–HLA-DR1 complex , 2011, Proceedings of the National Academy of Sciences.
[120] G. Georgiou,et al. Antibody affinity maturation using bacterial surface display. , 1998, Protein engineering.
[121] M. Geiser,et al. Evaluation of antibodies fused to minor coat protein III and major coat protein VIII of bacteriophage M13. , 1995, Gene.
[122] R. Aitken,et al. Antibody phage display : methods and protocols , 2009 .
[123] M. Taussig,et al. Ribosome display: cell-free protein display technology. , 2002, Briefings in functional genomics & proteomics.
[124] C. Barbas,et al. Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[125] K Dane Wittrup,et al. Engineering an antibody with picomolar affinity to DOTA chelates of multiple radionuclides for pretargeted radioimmunotherapy and imaging. , 2011, Nuclear medicine and biology.
[126] Sachdev S Sidhu,et al. Synthetic antibodies from a four-amino-acid code: a dominant role for tyrosine in antigen recognition. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[127] N. Tsurushita,et al. Whole IgG surface display on mammalian cells: Application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies. , 2007, Journal of immunological methods.
[128] D R Burton,et al. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[129] John B. Shoven,et al. I , Edinburgh Medical and Surgical Journal.
[130] Xiaodong Cen,et al. Construction of a large phage display antibody library by in vitro package and in vivo recombination , 2006, Applied Microbiology and Biotechnology.
[131] W. Renner,et al. Prophylactic and therapeutic activity of fully human monoclonal antibodies directed against Influenza A M2 protein , 2009, Virology Journal.
[132] Frederic A. Fellouse,et al. High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries. , 2007, Journal of molecular biology.