Effect Of Smoking On Thyroid Status In Depression

Research Problem: Whal is Ihe impact of smoking cigarettes on thyroid functions in depression patients. Objective: To estimate T 3 , T 4 and TSH in depressed smokers. Study Design:   Hospital   based clinical  study. Setting: Psychiatry out - door patients. Participants: Depression patients with or without history of smoking. Sample Size:     Twenty five  patients  of depression. Study Variables: Smoking, Non - smoking, T 3 , T 4 , TSH Statistical Analysis: Student t- test. Result: The patients of both the study group and control group had subnormal T 3 but in smokers it was significantly lower than in non - smoker patients. T 4 was within the normal range in both the groups, but it was significantly higher in smokers. TSH levels were normal in both the groups of patients and there was no significant difference between the two groups. Conclusion: A low T 3 state exists in depression with further worsening of the condition in depressed patients who smoke, which might have an impact on therapeutic outcome. Therefore, avoidance of smoking in depression patients is suggested

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