Nonclinical toxicology development of a novel antibody antibiotic conjugate for treating invasive Staphylococcus Aureus infections
暂无分享,去创建一个
A. Kamath | W. Halpern | P. Katavolos | Kirsten Achilles-Poon | M. Carrasco-Triguero | H. Cai | N. Stagg | Nina Ljumanovic | Shelly Zhong
[1] N. Lewin-Koh,et al. Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging , 2019, PloS one.
[2] N. Lewin-Koh,et al. A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti-Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers , 2019, Antimicrobial Agents and Chemotherapy.
[3] W. Schaffner,et al. Invasive Methicillin-Resistant Staphylococcus aureus Infections Among Persons Who Inject Drugs — Six Sites, 2005–2016 , 2018, MMWR. Morbidity and mortality weekly report.
[4] S. Lehar,et al. Pharmacokinetics and pharmacodynamics of DSTA4637A: A novel THIOMAB™ antibody antibiotic conjugate against Staphylococcus aureus in mice , 2016, mAbs.
[5] P. S. Andersen,et al. Novel antibody–antibiotic conjugate eliminates intracellular S. aureus , 2015, Nature.
[6] S. V. van Hal,et al. Predictors of Mortality in Staphylococcus aureus Bacteremia , 2012, Clinical Microbiology Reviews.
[7] W. Kelley,et al. Staphylococcus aureus: new evidence for intracellular persistence. , 2009, Trends in microbiology.
[8] J. Fraile,et al. Endocarditis Caused by Staphylococcus aureus: A Reappraisal of the Epidemiologic, Clinical, and Pathologic Manifestations With Analysis of Factors Determining Outcome , 2009, Medicine.
[9] M. Holdiness. Teratology of the antituberculosis drugs. , 1987, Early human development.