Platelet-derived factors impair placental chorionic gonadotropin beta-subunit synthesis

[1]  J. James,et al.  Human placenta and trophoblast development: key molecular mechanisms and model systems , 2019, Cellular and Molecular Life Sciences.

[2]  G. Burton,et al.  Early first trimester uteroplacental flow and the progressive disintegration of spiral artery plugs: new insights from contrast-enhanced ultrasound and tissue histopathology , 2017, Human reproduction.

[3]  K. Nicolaides,et al.  Aspirin for the prevention of preterm and term preeclampsia: systematic review and metaanalysis , 2017, American journal of obstetrics and gynecology.

[4]  J. Cross,et al.  Fine-Tuned and Cell-Cycle-Restricted Expression of Fusogenic Protein Syncytin-2 Maintains Functional Placental Syncytia. , 2017, Cell reports.

[5]  C. Fiala,et al.  Expression pattern and phosphorylation status of Smad2/3 in different subtypes of human first trimester trophoblast. , 2017, Placenta.

[6]  A. Prokesch,et al.  Downregulation of p53 drives autophagy during human trophoblast differentiation , 2017, Cellular and Molecular Life Sciences.

[7]  B. Isermann,et al.  p45 NF-E2 regulates syncytiotrophoblast differentiation by post-translational GCM1 modifications in human intrauterine growth restriction , 2017, Cell Death & Disease.

[8]  B. Isermann,et al.  Placental hemostasis and sterile inflammation: New insights into gestational vascular disease. , 2017, Thrombosis research.

[9]  B. Isermann,et al.  Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts. , 2016, Blood.

[10]  M. Post,et al.  Aberrant TGFβ Signaling Contributes to Altered Trophoblast Differentiation in Preeclampsia. , 2016, Endocrinology.

[11]  B. Huppertz,et al.  TNF-α alters the inflammatory secretion profile of human first trimester placenta , 2016, Laboratory Investigation.

[12]  B. Huppertz,et al.  Evidence from the very beginning: endoglandular trophoblasts penetrate and replace uterine glands in situ and in vitro. , 2015, Human reproduction.

[13]  A. Blaschitz,et al.  Adhering maternal platelets can contribute to the cytokine and chemokine cocktail released by human first trimester villous placenta. , 2015, Placenta.

[14]  B. Huppertz,et al.  Placental fractalkine is up-regulated in severe early-onset preeclampsia. , 2015, The American journal of pathology.

[15]  B. Åsvold,et al.  Concentrations of human chorionic gonadotrophin in very early pregnancy and subsequent pre-eclampsia: a cohort study. , 2014, Human reproduction.

[16]  J. M. Robinson,et al.  Cell fusion mediates dramatic alterations in the actin cytoskeleton, focal adhesions, and E‐cadherin in trophoblastic cells , 2014, Cytoskeleton.

[17]  U. Stenman,et al.  First trimester hyperglycosylated human chorionic gonadotrophin in serum - a marker of early-onset preeclampsia. , 2013, Placenta.

[18]  J. Kingdom,et al.  Revisiting the housekeeping genes of human placental development and insufficiency syndromes. , 2012, Placenta.

[19]  B. Huppertz,et al.  A Variety of Opportunities for Immune Interactions During Trophoblast Development and Invasion , 2012, American journal of reproductive immunology.

[20]  L. Cole hCG, the wonder of today's science , 2012, Reproductive Biology and Endocrinology.

[21]  Brian K. Hall,et al.  Correction: Lactation Defect with Impaired Secretory Activation in AEBP1-Null Mice , 2011, PLoS ONE.

[22]  G. Rivard,et al.  Is testing for aspirin response worthwhile in high-risk pregnancy? , 2011, European journal of obstetrics, gynecology, and reproductive biology.

[23]  B. Huppertz,et al.  The choriocarcinoma cell line BeWo: syncytial fusion and expression of syncytium-specific proteins. , 2010, Reproduction.

[24]  M. Westwood,et al.  Transforming growth factor-{beta} (TGF{beta}) receptors I/II differentially regulate TGF{beta}1 and IGF-binding protein-3 mitogenic effects in the human placenta. , 2010, Endocrinology.

[25]  B. Huppertz,et al.  Caspases rather than calpains mediate remodelling of the fodrin skeleton during human placental trophoblast fusion , 2010, Cell Death and Differentiation.

[26]  L. Cole hCG and hyperglycosylated hCG in the establishment and evolution of hemochorial placentation. , 2009, Journal of reproductive immunology.

[27]  D. Strunk,et al.  Preparation of pooled human platelet lysate (pHPL) as an efficient supplement for animal serum-free human stem cell cultures. , 2009, Journal of visualized experiments : JoVE.

[28]  T. Luger,et al.  Increased cAMP Levels Modulate Transforming Growth Factor-β/Smad-induced Expression of Extracellular Matrix Components and Other Key Fibroblast Effector Functions , 2009, The Journal of Biological Chemistry.

[29]  D. Strunk,et al.  Human Alternatives to Fetal Bovine Serum for the Expansion of Mesenchymal Stromal Cells from Bone Marrow , 2009, Stem cells.

[30]  J. Kingdom,et al.  Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast , 2009, Cell Death and Differentiation.

[31]  B. Huppertz,et al.  Factors involved in regulating trophoblast fusion: potential role in the development of preeclampsia. , 2009, Placenta.

[32]  E. Johnstone,et al.  Epidermal Growth Factor Stimulation of Trophoblast Differentiation Requires MAPK11/14 (p38 MAP Kinase) Activation , 2005, Biology of reproduction.

[33]  S. Fujii,et al.  Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries. , 2005, Blood.

[34]  L. Abécassis,et al.  Evidence for a Role of MSK1 in Transforming Growth Factor-β-mediated Responses through p38α and Smad Signaling Pathways* , 2004, Journal of Biological Chemistry.

[35]  L. Lund,et al.  Urokinase receptor is up-regulated in endothelial cells and macrophages associated with fibrinoid deposits in the human placenta. , 2003, Placenta.

[36]  T. Mayhew,et al.  Maternal diabetes mellitus is associated with altered deposition of fibrin-type fibrinoid at the villous surface in term placentae. , 2003, Placenta.

[37]  Dongning Wu,et al.  Transforming growth factor-beta1 inhibits steroidogenesis in human trophoblast cells. , 2002, Molecular human reproduction.

[38]  B. Bresnihan,et al.  Activation of Nuclear Orphan Receptor NURR1 Transcription by NF-κB and Cyclic Adenosine 5′-Monophosphate Response Element-Binding Protein in Rheumatoid Arthritis Synovial Tissue1 , 2002, The Journal of Immunology.

[39]  P. Husslein,et al.  Promoter Elements and Transcription Factors Involved in Differentiation-Dependent Human Chorionic Gonadotrophin-α Messenger Ribonucleic Acid Expression of Term Villous Trophoblasts. , 2000, Endocrinology.

[40]  A. Bretscher Regulation of cortical structure by the ezrin-radixin-moesin protein family. , 1999, Current opinion in cell biology.

[41]  Denis Vivien,et al.  Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene , 1998, The EMBO journal.

[42]  D. Nelson,et al.  Ontogenetic and phylogenetic evaluation of the presence of fibrin-type fibrinoid in the villous haemochorial placenta. , 1997, Placenta.

[43]  B. Huppertz,et al.  The fibrinoids of the human placenta: origin, composition and functional relevance. , 1996, Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.

[44]  J. Gilabert,et al.  Fibrinolytic system and reproductive process with special reference to fibrinolytic failure in pre-eclampsia. , 1995, Human reproduction.

[45]  J. Lin,et al.  Novel role of human chorionic gonadotropin in differentiation of human cytotrophoblasts. , 1993, Endocrinology.

[46]  D. Morrish,et al.  Transforming growth factor beta 1 inhibits placental differentiation and human chorionic gonadotropin and human placental lactogen secretion. , 1991, Endocrinology.

[47]  D. Nelson,et al.  Trophoblast interaction with fibrin matrix. Epithelialization of perivillous fibrin deposits as a mechanism for villous repair in the human placenta. , 1990, The American journal of pathology.

[48]  F. Prefumo,et al.  Association between birth weight and first-trimester free beta-human chorionic gonadotropin and pregnancy-associated plasma protein A. , 2008, Fertility and sterility.

[49]  L. Abécassis,et al.  Evidence for a role of MSK1 in transforming growth factor-beta-mediated responses through p38alpha and Smad signaling pathways. , 2004, The Journal of biological chemistry.

[50]  P. Husslein,et al.  Promoter elements and transcription factors involved in differentiation-dependent human chorionic gonadotrophin-alpha messenger ribonucleic acid expression of term villous trophoblasts. , 2000, Endocrinology.

[51]  A. Flahault,et al.  Increased placental antifibrinolytic potential and fibrin deposits in pregnancy-induced hypertension and preeclampsia. , 1996, Laboratory investigation; a journal of technical methods and pathology.

[52]  Y. Song,et al.  Activin-A stimulates, while transforming growth factor beta 1 inhibits, chorionic gonadotrophin production and aromatase activity in cultured human placental trophoblasts. , 1996, Placenta.