Blood Flow and Pressure Change Simulation in the Aorta with the Model Generated from CT Data

We have performed the blood flow and the pressure change simulation in the aorta with the model generated from CT (Computerized Tomography) data. There have been some previous researches related to the aortic valve and the blood flow in the aorta. Some works simulated the aortic valve behavior with artificial models, and others investigated the blood flow in the aorta with models generated from MRI (Magnetic Resonance Imaging) data. In this paper, we demonstrate the simulation of the blood flow and the pressure change in the aorta with a model generated from CT data, which model includes not only the aorta but also the left ventricle. In the simulation, blood flows into the left ventricle through the mitral valve, the pressure increases according to the blood flow that moves into the left ventricle through the mitral valve, and the aortic valve opens by the pressure increase in the left ventricle. Finally, we have confirmed that the pressure change in the left ventricle corresponds to a literature value.

[1]  Nobuhiko Mukai,et al.  Particle-based Simulation on Aortic Valve Behavior with CG Model Generated from CT , 2016, VISIGRAPP.

[2]  Patrick Patrick Anderson,et al.  Fluid-solid interactions: modeling, simulation, bio-mechanical applications A three-dimensional fluid-structure interaction method for heart valve modelling , 2005 .

[3]  G. G. Peters,et al.  A two-dimensional fluid–structure interaction model of the aortic value , 2000 .

[4]  R. Cheng,et al.  Three-Dimensional Fluid-Structure Interaction Simulation of Bileaflet Mechanical Heart Valve Flow Dynamics , 2004, Annals of Biomedical Engineering.

[5]  Fotis Sotiropoulos,et al.  Fluid-structure interaction of an aortic heart valve prosthesis driven by an animated anatomic left ventricle , 2013, J. Comput. Phys..

[6]  John F LaDisa,et al.  Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation. , 2013, Medical engineering & physics.

[7]  Yuri Bazilevs,et al.  Dynamic and fluid–structure interaction simulations of bioprosthetic heart valves using parametric design with T-splines and Fung-type material models , 2015, Computational mechanics.

[8]  F P T Baaijens,et al.  A three-dimensional computational analysis of fluid-structure interaction in the aortic valve. , 2003, Journal of biomechanics.

[9]  Dong Ha Kim,et al.  The blood flow simulations of human aortic arch model with major branches , 2011, 2011 4th International Conference on Biomedical Engineering and Informatics (BMEI).

[10]  Thomas J. R. Hughes,et al.  Fluid–structure interaction analysis of bioprosthetic heart valves: significance of arterial wall deformation , 2014, Computational Mechanics.

[11]  J. Levick,et al.  An Introduction to Cardiovascular Physiology , 2009 .

[12]  Yusuke Abe,et al.  Particle Based Simulation of the Aortic Valve by Considering Heart's Pulsation , 2014, MMVR.

[13]  I. C. Howard,et al.  An approach to the simulation of fluid-structure interaction in the aortic valve. , 2006, Journal of biomechanics.