Emerging and reemerging infectious diseases: a multidisciplinary perspective.

Predictions that infectious diseases would be eliminated as a major threat to human health have been shattered by emerging and reemerging infections, among them acquired immunodeficiency syndrome (AIDS), hemorrhagic fevers, marked increases in infections caused by antimicrobial-resistant bacteria, and the resurgence of tuberculosis and malaria. Understanding the dynamics of emerging and reemerging infections is critical to efforts to reduce the morbidity and mortality of such infections, to establish policy related to preparedness for infectious threats, and for decisions on where to use limited resources in the fight against infections. In order to offer a multidisciplinary perspective, 23 infectious disease specialists, epidemiologists, geneticists, microbiologists, and population biologists participated in an open forum at Emory University on emerging and reemerging infectious diseases. As summarized below, the group addressed questions about the definition, the identification, the factors responsible for, and multidisciplinary approaches to emerging and reemerging infections.

[1]  P. Thrall,et al.  SEXUALLY TRANSMITTED DISEASES IN ANIMALS: ECOLOGICAL AND EVOLUTIONARY IMPLICATIONS , 1996, Biological reviews of the Cambridge Philosophical Society.

[2]  M. Cetron,et al.  The prevalence of drug-resistant Streptococcus pneumoniae in Atlanta. , 1995, The New England journal of medicine.

[3]  M. Nowak,et al.  The evolution of virulence in sexually transmitted HIV/AIDS. , 1995, Journal of theoretical biology.

[4]  A. Gould,et al.  A morbillivirus that caused fatal disease in horses and humans. , 1995, Science.

[5]  Peter H. Thrall,et al.  Frequency-Dependent Disease Transmission and the Dynamics of the Silene-Ustilago Host-Pathogen System , 1995, The American Naturalist.

[6]  Mary E. Wilson Disease in Evolution Introduction , 1994, Annals of the New York Academy of Sciences.

[7]  Mary E. Wilson,et al.  Disease in Evolution: Global Changes and Emergence of Infectious Diseases. Proceedings of a conference. Woods Hole, Massachusetts, November 7-10, 1993. , 1994, Annals of the New York Academy of Sciences.

[8]  L. Garrett The Coming Plague: Newly Emerging Diseases in a World Out of Balance , 1994 .

[9]  D. Ebert Virulence and Local Adaptation of a Horizontally Transmitted Parasite , 1994, Science.

[10]  Dobson Mj Malaria in England: a geographical and historical perspective. , 1994, Parassitologia.

[11]  G. Schoolnik,et al.  The light organ symbiont Vibrio fischeri possesses a homolog of the Vibrio cholerae transmembrane transcriptional activator ToxR , 1994, Journal of bacteriology.

[12]  C. Turner,et al.  Malaria parasites undergo antigenic variation at high rates in vivo , 1994, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[13]  P. Ewald Evolution of Infectious Disease , 1993 .

[14]  J. Childs,et al.  Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. , 1993, Science.

[15]  A. Schuchat,et al.  Increased risk of meningitis and bacteremia due to Listeria monocytogenes in patients with human immunodeficiency virus infection. , 1993, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[16]  A. Schuchat,et al.  A population-based assessment of invasive disease due to group B Streptococcus in nonpregnant adults. , 1993, The New England journal of medicine.

[17]  D H Walker,et al.  Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[18]  E. Herre Population Structure and the Evolution of Virulence in Nematode Parasites of Fig Wasps , 1993, Science.

[19]  P. Brown,et al.  "Friendly fire" in medicine: hormones, homografts, and Creutzfeldt-Jakob disease , 1992, The Lancet.

[20]  Kevin Marsh,et al.  Rapid switching to multiple antigenic and adhesive phenotypes in malaria , 1992, Nature.

[21]  E. Zell,et al.  Epidemiological features of pertussis in the United States, 1980-1989. , 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[22]  R. May,et al.  Infectious Diseases of Humans: Dynamics and Control , 1991, Annals of Internal Medicine.

[23]  M. Nettleman Biological warfare and infection control. , 1991, Infection control and hospital epidemiology.

[24]  D. Libby,et al.  A cluster of Pneumocystis carinii pneumonia in adults without predisposing illnesses. , 1991, The New England journal of medicine.

[25]  M. Blaser Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. , 1990, The Journal of infectious diseases.

[26]  R. Purcell,et al.  Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. , 1989, The New England journal of medicine.

[27]  P. Fultz,et al.  Identification and biologic characterization of an acutely lethal variant of simian immunodeficiency virus from sooty mangabeys (SIV/SMM). , 1989, AIDS research and human retroviruses.

[28]  M. Skurnik,et al.  Analysis of the yopA gene encoding the Yop1 virulence determinants of Yersinia spp. , 1989, Molecular microbiology.

[29]  H. M. Alexander,et al.  DISEASE SPREAD AND POPULATION DYNAMICS OF ANTHER-SMUT INFECTION OF SILENE ALBA CAUSED BY THE FUNGUS USTILAGO VIOLACEA , 1988 .

[30]  K. Cartwright,et al.  The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamica , 1987, Epidemiology and Infection.

[31]  K. Johnston Call for destruction of smallpox virus , 1987, Nature.

[32]  J. Murray Modeling the Spread of Rabies , 1987 .

[33]  K. Clay Induced vivipary in the sedge Cyperus virens and the transmission of the fungus Balansia cyperi (Clavicipitaceae) , 1986 .

[34]  K. Clay THE EFFECT OF THE FUNGUS ATKINSONELLA HYPOXYLON (CLAVICIPITACEAE)ON THE REPRODUCTIVE SYSTEM AND DEMOGRAPHY OF THE GRASS DANTHONIA SPICATA. , 1984, The New phytologist.

[35]  P. Fine,et al.  Measles in England and Wales--I: An analysis of factors underlying seasonal patterns. , 1982, International journal of epidemiology.

[36]  R. May,et al.  Population biology of infectious diseases: Part II , 1979, Nature.

[37]  V L Yu,et al.  Serratia marcescens: historical perspective and clinical review. , 1979 .

[38]  P. Brachman,et al.  Legionnaires' disease. , 1977, Disease-a-month : DM.

[39]  B. McNeil,et al.  The swine-influenza decision. , 1976, The New England journal of medicine.

[40]  V. Faber,et al.  Changing staphylococci and staphylococcal infections. A ten-year study of bacteria and cases of bacteremia. , 1969, The New England journal of medicine.

[41]  F. J. Roethlisberger,et al.  Management and the Worker , 1941 .

[42]  S. Morse,et al.  Factors in the emergence of infectious diseases. , 1995, Emerging infectious diseases.

[43]  J. Wells,et al.  Molecular subtyping of toxigenic Vibrio cholerae O139 causing epidemic cholera in India and Bangladesh, 1992-1993. , 1995, The Journal of infectious diseases.

[44]  J. Elkinton,et al.  Using simple models to predict virus epizootics in gypsy moth populations , 1993 .

[45]  Joshua Lederberg,et al.  Emerging Infections: Microbial Threats to Health in the United States , 1992 .

[46]  Peter J. Hudson,et al.  system: Trichostrongylus tenuis in red grouse. II. Population models , 1992 .

[47]  D. Stevens Invasive group A streptococcus infections. , 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[48]  R. Tauxe,et al.  The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorrhagic E. coli, and the associated hemolytic uremic syndrome. , 1991, Epidemiologic reviews.

[49]  H. Hethcote,et al.  Measles and rubella in the United States. , 1983, American journal of epidemiology.

[50]  R. May Parasitic infections as regulators of animal populations. , 1983, American scientist.

[51]  A. Steere,et al.  Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities. , 1977, Arthritis and rheumatism.

[52]  K. Johnson,et al.  Isolation of Machupo virus from wild rodent Calomys callosus. , 1966, American Journal of Tropical Medicine and Hygiene.