论文信息 - Cytochrome P450

Cytochrome P450

[1] Stephen R. Wilson,et al. Silicon-mediated suicide inhibition: an efficient mechanism-based inhibitor of cytochrome P-450scc oxidation of cholesterol , 1984 .

[2] K. Ozato,et al. Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction , 1989, Molecular and cellular biology.

[3] C. Wolf,et al. Mammalian genes expressed in Drosophila: a transgenic model for the study of mechanisms of chemical mutagenesis and metabolism. , 1991, The EMBO journal.

[4] C. Kozak,et al. The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping. , 1990, Biochemistry.

[5] R. Kato,et al. Complete cDNA sequence of a major 3-methylcholanthrene-inducible cytochrome P-450 isozyme (P-450AFB) of Syrian hamsters with high activity toward aflatoxin B1. , 1989, Biochemical and biophysical research communications.

[6] C. Ioannides,et al. The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals. , 1990, Drug metabolism reviews.

[7] J. Gustafsson,et al. Effects of treatment with chenodeoxycholic acid on liver microsomal metabolism of steroids in man. , 1980, The Journal of laboratory and clinical medicine.

[8] H. Pitot,et al. The expression and metabolic activity of cytochrome P-450 isozymes in control and phenobarbital-induced primary cultures of rat hepatocytes. , 1988, Archives of biochemistry and biophysics.

[9] J. Stegeman,et al. Cytochrome P-450 monooxygenase systems in aquatic species: carcinogen metabolism and biomarkers for carcinogen and pollutant exposure. , 1991, Environmental health perspectives.

[10] R. Sato,et al. Yeast cytochrome P-450 catalyzing lanosterol 14 alpha-demethylation. II. Lanosterol metabolism by purified P-450(14)DM and by intact microsomes. , 1984, The Journal of biological chemistry.

[11] R. Kumar,et al. The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3. , 1986, Kidney international.

[12] M. Berenbaum,et al. A host-inducible cytochrome P-450 from a host-specific caterpillar: molecular cloning and evolution. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[13] R. Russell,et al. Effect of aging on in vivo and in vitro ethanol metabolism and its toxicity in F344 rats. , 1989, Gastroenterology.

[14] E. Bresnick,et al. Nuclear uptake and subsequent nuclear metabolism of benzo(a)pyrene complexed to cytosolic proteins. , 1981, Cancer research.

[15] P. White,et al. Nonsense mutation causing steroid 21-hydroxylase deficiency. , 1988, The Journal of clinical investigation.

[16] H. Danielsson. Influence of dietary bile acids on formation of bile acids in rat. , 1973, Steroids.

[17] C. Miranda,et al. Immunological characterization of constitutive isozymes of cytochrome P-450 from rainbow trout. Evidence for homology with phenobarbital-induced rat P-450s. , 1990, Biochimica et biophysica acta.

[18] H. Shoun,et al. Denitrification by the fungus Fusarium oxysporum and involvement of cytochrome P-450 in the respiratory nitrite reduction. , 1991, The Journal of biological chemistry.

[19] Y. Fujii‐Kuriyama,et al. Alternative splicing mechanism in a cytochrome P-450 (P-450PB-1) gene generates the two mRNAs coding for proteins of different functions. , 1989, The Journal of biological chemistry.

[20] E. Bresnick,et al. Implication of the "4S" polycyclic aromatic hydrocarbon binding protein in the transregulation of rat cytochrome P-450c expression. , 1985, Biochemistry.

[21] B. Roos,et al. 25,26-Dihydroxycholecalciferol: a precursor in the renal synthesis of 25-hydroxycholecalciferol-26,23-lactone. , 1980, Biochemical and biophysical research communications.

[22] J. Richards,et al. Rat cholesterol side-chain cleavage cytochrome P-450 (P-450scc) gene. Structure and regulation by cAMP in vitro. , 1990, The Journal of biological chemistry.

[23] D W Nebert,et al. Proposed role of drug-metabolizing enzymes: regulation of steady state levels of the ligands that effect growth, homeostasis, differentiation, and neuroendocrine functions. , 1991, Molecular endocrinology.

[24] K. Anderson,et al. Dietary regulation of cytochrome P450. , 1991, Annual review of nutrition.

[25] C. Kozak,et al. The rat P450IIE1 gene: complete intron and exon sequence, chromosome mapping, and correlation of developmental expression with specific 5' cytosine demethylation. , 1988, The Journal of biological chemistry.

[26] J. Goldstein,et al. Phenotypic differences in expression of cytochrome P-450g but not its mRNA in outbred male Sprague-Dawley rats. , 1987, Archives of biochemistry and biophysics.

[27] C. Kasper,et al. Transcriptional regulation of rat liver epoxide hydratase, NADPH-Cytochrome P-450 oxidoreductase, and cytochrome P-450b genes by phenobarbital. , 1983, The Journal of biological chemistry.

[28] G. Perdew. Association of the Ah receptor with the 90-kDa heat shock protein. , 1988, The Journal of biological chemistry.

[29] K. Nakao,et al. Cloning of cDNA and genomic DNA for human cytochrome P‐45011β , 1990, FEBS letters.

[30] W. Miller,et al. Extraadrenal steroid 21-hydroxylation is not mediated by P450c21. , 1989, The Journal of clinical investigation.

[31] Y. Yoshida,et al. The 14alpha-demethylation of lanosterol by a reconstituted cytochrome P-450 system from yeast microsomes. , 1978, Biochemical and biophysical research communications.

[32] C. Kasper,et al. Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone-16 alpha-carbonitrile. Characterization of its mRNA, gene, and induction response. , 1983, The Journal of biological chemistry.

[33] 青山由利,et al. Metabolism of 32-hydroxy-24, 25-dihydrolanosterol by purified cytochrome P-450₁₄DM from yeast , 1987 .

[34] D. Crawford,et al. Degradation of phenol by Streptomyces setonii , 1983 .

[35] F. Gonzalez,et al. The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and CYP2A3. , 1991, Carcinogenesis.

[36] W. Miller,et al. CONGENITAL ADRENAL HYPERPLASIA DUE TO DEFICIENT CHOLESTEROL SIDE‐CHAIN CLEAVAGE ACTIVITY (20, 22‐DESMOLASE) IN A PATIENT TREATED FOR 18 YEARS , 1985, Clinical endocrinology.

[37] M. Waterman,et al. The hydrophobic amino-terminal sequence of bovine 17 alpha-hydroxylase is required for the expression of a functional hemoprotein in COS 1 cells. , 1991, The Journal of biological chemistry.

[38] D. Nebert,et al. Stable expression of mouse Cyp1a1 and human CYP1A2 cDNAs transfected into mouse hepatoma cells lacking detectable P450 enzyme activity. , 1990, DNA and cell biology.

[39] D. Nebert,et al. Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22. , 1988, Genomics.

[40] P. Maurel,et al. Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450. , 1990, Gastroenterology.

[41] M. J. Coon,et al. Interactions of cytochrome P-450, NADPH-cytochrome P-450 reductase, phospholipid, and substrate in the reconstituted liver microsomal enzyme system. , 1980, The Journal of biological chemistry.

[42] H. Gelboin,et al. THE STIMULATORY EFFECT OF 3-METHYLCHOLANTHRENE ON BENZPYRENE HYDROXYLASE ACTIVITY IN SEVERAL RAT TISSUES: INHIBITION BY ACTINOMYCIN D AND PUROMYCIN. , 1964, Cancer research.

[43] D. Nebert,et al. Trout P450IA1: cDNA and deduced protein sequence, expression in liver, and evolutionary significance. , 1988, DNA.

[44] H. DeLuca,et al. Measurement of mammalian 25-hydroxyvitamin D3 24R-and 1 alpha-hydroxylase. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[45] Y. Fujii‐Kuriyama,et al. Structures of regulatory regions in the human cytochrome P-450scc (desmolase) gene. , 1991, European journal of biochemistry.

[46] E. Chambaz,et al. Phosphorylation of purified mitochondrial cytochromes P-450 (cholesterol desmolase and 11β-hydroxylase) from bovine adrenal cortex , 1982, Molecular and Cellular Endocrinology.

[47] O. Hankinson,et al. Cloning of a factor required for activity of the Ah (dioxin) receptor. , 1991, Science.

[48] J. Schenkman,et al. Purification and characterization of a new form (RLM2) of liver microsomal cytochrome P-450 from untreated rat. , 1985, The Journal of biological chemistry.

[49] C. Jefcoate,et al. Adrenal mitochondrial cytochrome P-450scc. Cholesterol and adrenodoxin interactions at equilibrium and during turnover. , 1981, The Journal of biological chemistry.

[50] A. Y. Lu,et al. Studies on the stimulation of cytochrome P-450-dependent monooxygenase activity by dilauroylphosphatidylcholine. , 1981, Archives of biochemistry and biophysics.

[51] R. Skoda,et al. Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[52] M. Waterman,et al. Construction and expression of human/bovine P45017 alpha chimeric proteins: evidence for distinct tertiary structures in the same P450 from two different species. , 1990, Biochemistry.

[53] J. Gustafsson,et al. A dual role of growth hormone as a feminizing and masculinizing factor in the control of sex-specific cytochrome P-450 isozymes in rat liver. , 1989, The Journal of endocrinology.

[54] W. H. Elliott,et al. The cDNA and protein sequence of a phenobarbital-induced chicken cytochrome P-450. , 1986, The Journal of biological chemistry.

[55] T. Beppu,et al. Subterminal hydroxylation of fatty acids by a cytochrome P-450-dependent enzyme system from a fungus, Fusarium oxysporum. , 1985, Journal of biochemistry.

[56] J. Lambeth,et al. Ionic effects on adrenal steroidogenic electron transport. The role of adrenodoxin as an electron shuttle. , 1979, The Journal of biological chemistry.

[57] C. Walsh,et al. Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat liver. , 1983, The Journal of biological chemistry.

[58] P. Thomas,et al. Age- and sex-related expression of cytochromes p450f and P450g in rat liver. , 1986, Archives of biochemistry and biophysics.

[59] R. Hansson. Effect of diabetes, starvation, ethanol and isoniazid on rat liver microsomal 12 alpha-hydroxylase activity involved in bile acid biosynthesis. , 1989, Biochemical pharmacology.

[60] K. Parker,et al. A shared promoter element regulates the expression of three steroidogenic enzymes. , 1991, Molecular endocrinology.

[61] P. Beaune,et al. Expression of cytochrome P-450 enzymes in cultured human hepatocytes. , 1990, European journal of biochemistry.

[62] T. Getchell,et al. Odorant and Autonomic Regulation of Secretion in the Olfactory Mucosa , 1988 .

[63] M. Noshiro,et al. Pretranslational regulation of sex-dependent testosterone hydroxylases by growth hormone in mouse liver. , 1986, The Journal of biological chemistry.

[64] M. J. Coon,et al. Induction of cytochrome P-450 isozyme 3a (P-450IIE1) in rabbit olfactory mucosa by ethanol and acetone. , 1990, Drug metabolism and disposition: the biological fate of chemicals.

[65] P. Srivastava,et al. Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase. , 1988, Biochemistry.

[66] H. Murakami,et al. Expression of bovine cytochrome P450c21 and its fused enzymes with yeast NADPH-cytochrome P450 reductase in Saccharomyces cerevisiae. , 1990, DNA and cell biology.

[67] H. Strobel,et al. Cytochrome P450 activity and distribution in the human colon mucosa , 1989, Cancer.

[68] M. Okamoto,et al. Aldosterone biosynthesis in mitochondria of isolated zones of adrenal cortex. , 1988, Journal of steroid biochemistry.

[69] O. Gotoh,et al. Nucleotide sequence of the unique nitrate/nitrite-inducible cytochrome P-450 cDNA from Fusarium oxysporum. , 1991, The Journal of biological chemistry.

[70] D. Kunz,et al. Identification of transformation products arising from bacterial oxidation of codeine by Streptomyces griseus , 1985, Applied and environmental microbiology.

[71] E. Glover,et al. Ca2+-dependent proteolysis of the Ah receptor. , 1988, Archives of biochemistry and biophysics.

[72] M. Waterman,et al. Cell-free synthesis of precursor forms of mitochondrial steroid hydroxylase enzymes of the bovine adrenal cortex. , 1982, Archives of biochemistry and biophysics.

[73] J. Goldstein,et al. Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes. , 1990, Biochemistry.

[74] E. Roscher,et al. Mutagenicity, clastogenicity and cytotoxicity of procarcinogens in a rat hepatoma cell line competent for xenobiotic metabolism. , 1988, Mutagenesis.

[75] T. Omura,et al. Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex. , 1983, Journal of biochemistry.

[76] C. Wade,et al. Lipid lateral diffusion by pulsed nuclear magnetic resonance. , 1979, Biochemistry.

[77] M. J. Coon,et al. Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components. , 1969, The Journal of biological chemistry.

[78] G. Scatchard,et al. THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS , 1949 .

[79] P. Watkins,et al. Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. , 1987, The Journal of clinical investigation.

[80] R. Feyereisen,et al. Characterization of antibodies to house fly NADPH-cytochrome P-450 reductase , 1984 .

[81] Sanford P. Markey,et al. Chronic parkinsonism secondary to intravenous injection of meperidine analogues , 1979, Psychiatry Research.

[82] A. S. Gross,et al. The genetic polymorphism of debrisoquine/sparteine metabolism--clinical aspects. , 1990, Pharmacology & therapeutics.

[83] T. Ogishima,et al. Isolation of aldosterone synthase cytochrome P-450 from zona glomerulosa mitochondria of rat adrenal cortex. , 1989, The Journal of biological chemistry.

[84] D. Hultquist,et al. Soluble cytochrome b 5 reductase from human erythrocytes. , 1972, Biochimica et biophysica acta.

[85] Z. A. Trapeznikova. On the Interaction of , 1959 .

[86] M. Ingelman-Sundberg,et al. Substrate-, hormone-, and cAMP-regulated cytochrome P450 degradation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[87] D. Nebert,et al. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism , 1988, Nature.

[88] C. Kasper,et al. Quantitation of mRNAs specific for the mixed-function oxidase system in rat liver and extrahepatic tissues during development. , 1989, Archives of biochemistry and biophysics.

[89] R. Walford,et al. Influence of age and caloric restriction on expression of hepatic genes for xenobiotic and oxygen metabolizing enzymes in the mouse. , 1991, Journal of gerontology.

[90] R. Langenbach,et al. Development of a human cell line by selection and drug-metabolizing gene transfection with increased capacity to activate promutagens. , 1989, Carcinogenesis.

[91] T. Aoyama,et al. cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver. , 1989, Biochemistry.

[92] J. Weisburger. Chemical carcinogens and their mode of action in colonic neoplasia , 1973, Diseases of the colon and rectum.

[93] S. Koritz,et al. On the mechanism of action of the adrenocorticotrophic hormone. The stimulation of the activity of enzymes involved in pregnenolone synthesis. , 1970, The Journal of biological chemistry.

[94] E. Lock,et al. NADPH: cytochrome P-450 reductase in olfactory epithelium. Relevance to cytochrome P-450-dependent reactions. , 1986, The Biochemical journal.

[95] F. Althaus,et al. Effects of phenobarbital, beta-naphthoflavone, dexamethasone, and formamidoxime on the turnover of inducible microsomal proteins in cultured hepatocytes. , 1981, The Journal of biological chemistry.

[96] K. Mitropoulos,et al. Evidence that the oxidation of the side chain of cholesterol by liver mitochondria is stereospecific, and that the immediate product of cleavage is propionate. , 1965, The Biochemical journal.

[97] M. Ingelman-Sundberg,et al. DISASSOCIATION BETWEEN DEBRISOQUINE HYDROXYLATION PHENOTYPE AND GENOTYPE AMONG CHINESE , 1989, The Lancet.

[98] J. I. Pedersen,et al. Role of the 26-hydroxylase in the biosynthesis of bile acids in the normal state and in cerebrotendinous xanthomatosis. An in vivo study. , 1983, The Journal of clinical investigation.

[99] J. Schenkman,et al. Effects of testosterone and growth hormone treatment on hepatic microsomal P450 expression in the diabetic rat. , 1990, Molecular pharmacology.

[100] R. Anderson,et al. Photosynthesis of previtamin D3 in human skin and the physiologic consequences. , 1980, Science.

[101] R. Gray,et al. Effect of a zwitterionic detergent on the state of aggregation and catalytic activity of cytochrome P-450LM2 and NADPH-cytochrome P-450 reductase. , 1984, The Journal of biological chemistry.

[102] M. J. Coon,et al. Properties of a yeast cytochrome P-450-containing enzyme system which catalyzes the hydroxylation of fatty acids, alkanes, and drugs. , 1973, European journal of biochemistry.

[103] P. Beaune,et al. Effects of ethanol and clofibrate on expression of cytochrome P-450 enzymes and epoxide hydrolase in cultures and cocultures of rat hepatocytes. , 1991, European journal of biochemistry.

[104] J. G. Ghazarian. Perspectives: The renal mitochondrial hydroxylases of the vitamin D3 endocrine complex: How are they regulated at the molecular level? , 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[105] W. Miller,et al. Regional mapping of genes encoding human steroidogenic enzymes: P450scc to 15q23-q24, adrenodoxin to 11q22; adrenodoxin reductase to 17q24-q25; and P450c17 to 10q24-q25. , 1991, DNA and cell biology.

[106] I. Björkhem. Chapter 9 Mechanism of bile acid biosynthesis in mammalian liver , 1985 .

[107] P. Sinclair,et al. Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription. , 1991, Archives of biochemistry and biophysics.

[108] M. Wagner,et al. A hybrid cell mapping panel for regional localization of probes to human chromosome 8. , 1991, Genomics.

[109] M. J. Coon,et al. Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states. , 1978, The Journal of biological chemistry.

[110] F. Gonzalez,et al. Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization. , 1989, The Journal of biological chemistry.

[111] H. Strobel,et al. Metabolism of the carcinogen 1,2‐dimethylhydrazine by isolated human colon microsomes and human colon tumor cells in culture , 1983, Cancer.

[112] K. Boo-Chai,et al. Aromatase activity in adipose tissue from breast quadrants: A link with tumor site , 1989 .

[113] L. Wu,et al. Organization and function of a dioxin-responsive enhancer. , 1990, The Journal of biological chemistry.

[114] F. Guengerich,et al. Hydrodynamic characterization of highly purified and functionally active liver microsomal cytochrome P-450. , 1979, Biochemistry.

[115] V. Coghlan,et al. Site-specific mutations in human ferredoxin that affect binding to ferredoxin reductase and cytochrome P450scc. , 1991, The Journal of biological chemistry.

[116] L. Vickery,et al. NMR studies of cytochrome P-450scc. Effects of steroid binding on water proton access to the active site of the ferric enzyme. , 1987, Biochemistry.

[117] P. Iversen,et al. Induction of cytochromes P450IA1 and P450IA2 as determined by solution hybridization. , 1991, Biochemical pharmacology.

[118] J. R. Smith,et al. Multiple sterol regulatory elements in promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A synthase. , 1988, The Journal of biological chemistry.

[119] Y. Sonoda,et al. Role of the side chain of lanosterol in substrate recognition and catalytic activity of lanosterol 14 alpha-demethylase (cytochrome P-450 (14DM)) of yeast. , 1991, Biochimica et biophysica acta.

[120] W L Miller,et al. Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[121] M. Akhtar,et al. The formation of an 8,14-diene system during cholesterol biosynthesis , 1969 .

[122] R. Greinert,et al. Cytochrome P-450 rotamers control mixed-function oxygenation in reconstituted membranes. Rotational diffusion studied by delayed fluorescence depolarization. , 1982, Xenobiotica; the fate of foreign compounds in biological systems.

[123] I. V. Nikitchenko,et al. [Activity of key enzymes of heme metabolism and the content of several hemoproteins in the liver of rats of various ages]. , 1989, Ukrainskii biokhimicheskii zhurnal.

[124] G. Darlington,et al. 26-hydroxycholesterol: regulation of hydroxymethylglutaryl-CoA reductase activity in Chinese hamster ovary cell culture. , 1983, Journal of lipid research.

[125] H. Strobel,et al. Reconstitution of the Brain Mixed Function Oxidase System: Purification of NADPH‐Cytochrome P450 Reductase and Partial Purification of Cytochrome P450 from Whole Rat Brain , 1992, Journal of neurochemistry.

[126] G. Gibson,et al. Cytochrome P-450 in the housefly: induction, substrate specificity and comparison to three rat hepatic isoenzymes. , 1989, Xenobiotica; the fate of foreign compounds in biological systems.

[127] E. Arinç,et al. Characterization of sheep liver and lung microsomal ethylmorphine N-demethylase. , 1985, Comparative biochemistry and physiology. B, Comparative biochemistry.

[128] C. Wolf,et al. cDNA and deduced amino acid sequence of a novel cytochrome P-450 from female rat liver mRNA with high homology to P-450 IIC family. , 1990, Nucleic acids research.

[129] M. Tsubaki,et al. Effects of cholesterol and adrenodoxin binding on the heme moiety of cytochrome P-450scc: a resonance Raman study. , 1986, Biochemistry.

[130] O. Takikawa,et al. Formation of a cytochrome P-450scc-adrenodoxin complex. , 1977, Biochemical and biophysical research communications.

[131] J. Adams,et al. Characterization of 1 alpha-hydroxylation of vitamin D3 sterols by cultured alveolar macrophages from patients with sarcoidosis , 1985, The Journal of experimental medicine.

[132] H. Strobel,et al. Activation of carcinogens and mutagens by rat colon mucosa. , 1978, Cancer research.

[133] C. Lieber,et al. Ethanol Oxidation by Hepatic Microsomes: Adaptive Increase after Ethanol Feeding , 1968, Science.

[134] A. Fiechter,et al. Heterogeneity within the alkane‐inducible cytochrome P450 gene family of the yeast Candida tropicalis , 1989, FEBS letters.

[135] P. Luc,et al. Glucocorticoid regulation of a phenobarbital-inducible cytochrome P-450 gene: the presence of a functional glucocorticoid response element in the 5'-flanking region of the CYP2B2 gene. , 1990, Nucleic acids research.

[136] M. Past,et al. Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450. , 1982, Biochemical pharmacology.

[137] W. Orme-Johnson,et al. Acetylenic mechanism-based inhibitors of cholesterol side chain cleavage by cytochrome P-450scc. , 1983, The Journal of biological chemistry.

[138] P. Poffenbarger,et al. Pharmacogenetics of Tolbutamide Metabolism in Humans , 1978, Diabetes.

[139] D. Seybert. Lipid regulation of bovine cytochrome P45011β activity , 1990 .

[140] C. Hansch,et al. Pyrazoles as effectors of ethanol oxidizing enzymes and inducers of cytochrome P450. , 1987, Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.

[141] M. Chiba,et al. Evaluation of the involvement of a male specific cytochrome P-450 isozyme in senescence-associated decline of hepatic drug metabolism in male rats. , 1989, Biochemical pharmacology.

[142] Crystallization of cytochrome P‐450scc from bovine adrenocortical mitochondria , 1988, FEBS letters.

[143] C. Wolf,et al. Induction of drug metabolizing enzymes in human liver cell line Hep G2 , 1985, FEBS letters.

[144] C. House,et al. The influence of basic residues on the substrate specificity of protein kinase C. , 1987, The Journal of biological chemistry.

[145] D. Perry,et al. Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 gene , 1990, Molecular and cellular biology.

[146] B. Schimmer,et al. Multiple regulatory elements determine adrenocortical expression of steroid 21-hydroxylase. , 1990, The Journal of biological chemistry.

[147] M. Fujita. Stimulation of Cytochrome P-450 Synthesis in Sliced Sweet Potato Root Tissue by Chemicals Applied to Surface , 1985 .

[148] R. Lindberg,et al. Characterization and regulation of sex-specific mouse steroid hydroxylase genes. , 1990, Canadian journal of physiology and pharmacology.

[149] S. Paul,et al. Estrogen-2-hydroxylase in the rat. Distribution and response to hormonal manipulation. , 1980, Biochemical Pharmacology.

[150] O. A. Young. Mixed function oxidases from germinating castor bean endosperm , 1976 .

[151] J. I. Pedersen,et al. Soluble 25-hydroxyvitamin D3-1α-hydroxylase from kidney mitochondria of rachitic pigs , 1978 .

[152] Y. Sonoda,et al. The 3-hydroxy group of lanosterol is essential for orienting the substrate in the substrate site of cytochrome P-45014DM (Lanosterol 14α-demethylase) , 1989 .

[153] H. Hauser,et al. Effect of chain length on the stability of lecithin bilayers. , 1973, Biochemical and biophysical research communications.

[154] R. Farese,et al. Polyphosphoinositides:stimulator of mitochondrial cholesterol side chain cleavage and possible identification as an adrenocorticotropin-induced, cycloheximide-sensitive, cytosolic, steroidogenic factor. , 1980, Endocrinology.

[155] H. Glatt,et al. Stable expression of rat cytochrome P-450IA1 cDNA in V79 Chinese hamster cells and their use in mutagenicity testing. , 1990, Molecular pharmacology.

[156] J. Rothman,et al. Asymmetric exchange of vesicle phospholipids catalyzed by the phosphatidylcholine exhange protein. Measurement of inside--outside transitions. , 1975, Biochemistry.

[157] Israel Hanukoglu,et al. Stoichiometry of mitochondrial cytochromes P-450, adrenodoxin and adrenodoxin reductase in adrenal cortex and corpus luteum. Implications for membrane organization and gene regulation. , 1986, European journal of biochemistry.

[158] J. Butte,et al. The Influence of Age on Steroidogenic Enzyme Activities of the Rat Adrenal Gland: Enhanced Expression of Cholesterol Side-Chain Cleavage Activity* , 1987, Endocrinology.

[159] M. J. Coon,et al. Cytochrome P-450-dependent formation of ethylene from N-nitrosoethylamines. , 1988, Drug metabolism and disposition: the biological fate of chemicals.

[160] K. McMasters,et al. Rat cholesterol side-chain cleavage enzyme (P-450scc): use of a cDNA probe to study the hormonal regulation of P-450scc mRNA levels in ovarian granulosa cells. , 1987, Gene.

[161] H. Shoun,et al. Soluble, nitrate/nitrite‐inducible cytochrome P‐450 of the fungus, Fusarium oxysporum , 1989, FEBS letters.

[162] B. Črešnar,et al. Resolution and reconstitution of cytochrome P-450 containing steroid hydroxylation system of Rhizopus nigricans. , 1987, Journal of steroid biochemistry.

[163] J. C. Loper,et al. Proteins from eight eukaryotic cytochrome P-450 families share a segmented region of sequence similarity. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[164] J. Whitlock,et al. Control of cytochrome P1-450 gene expression by dioxin. , 1985, Science.

[165] J. Gustafsson,et al. Uptake and specific binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the olfactory mucosa of mice and rats. , 1987, Cancer research.

[166] M. Negishi,et al. Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae. , 1991, Biochemistry.

[167] S. Nesnow,et al. Transfection of a Rat Cytochrome P450b cDNA Into C3H10T1/2CL8 Mouse Embryo Fibroblasts , 1989, Molecular carcinogenesis.

[168] J. Richards,et al. Molecular aspects of hormone action in ovarian follicular development, ovulation, and luteinization. , 1988, Annual review of physiology.

[169] W. Staib,et al. Effect of human chorionic gonadotropin and estradiol in vivo on estradiol binder and cytochrome P-450 concentrations in rat testis. , 1984, Journal of steroid biochemistry.

[170] R. Kerstetter,et al. Nucleotide sequence and analysis of the plant-inducible locus pinF from Agrobacterium tumefaciens , 1989, Journal of bacteriology.

[171] R. Kato,et al. Induction of cytochrome P-450c and P-450d by metyrapone in the primary culture of rat hepatocytes. , 1989, Japanese journal of pharmacology.

[172] A. Rahier,et al. Interaction of triazole fungicides and plant growth regulators with microsomal cytochrome P-450-dependent obtusifoliol 14α-methyl demethylase , 1988 .

[173] I. Holmberg,et al. Oxidation of 5β-cholestane-3α,7α,12α-triol into 3α,7α,12α-trihydroxy-5β-cholestanoic acid by cytochrome P-45026 from rabbit liver mitochondria , 1990 .

[174] J. Barilla,et al. Effects of age, adrenocorticotropin, and dexamethasone on a male-specific cytochrome P450 localized in the inner zone of the guinea pig adrenal. , 1989, Endocrinology.

[175] F. Guengerich,et al. Localization of a cytochrome P-450 isozyme (cytochrome P-450 PB-B) and NADPH-cytochrome P-450 reductase in rat nasal mucosa. , 1985, Cancer letters.

[176] U. Francke,et al. Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis. , 1991, The Journal of biological chemistry.

[177] S. Imaoka,et al. Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450. , 1990, Archives of biochemistry and biophysics.

[178] J. Hevel,et al. Tissue injury caused by deposition of immune complexes is L-arginine dependent. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[179] M. Waterman,et al. Evidence for a higher molecular weight precursor of cholesterol side-chain-cleavage cytochrome P-450 and induction of mitochondrial and cytosolic proteins by corticotropin in adult bovine adrenal cells. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[180] J. Maher,et al. Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver. , 1987, The Journal of clinical investigation.

[181] M. Tamura,et al. Effect of divalent cations on NADH-dependent and NADPH-dependent cytochrome b5 reduction by hepatic microsomes. , 1990, Archives of biochemistry and biophysics.

[182] T. Bunse,et al. Enzyme kinetic and inhibition analyses of cytochrome P450XVII, a protein with a bifunctional catalytic site. Quantification of effective substrate concentrations at the active site and their significance for intrinsic control of the hydroxylase/lyase reaction sequence. , 1991, The Journal of biological chemistry.

[183] J. Lech,et al. Biotransformation and induction: implications for toxicity, bioaccumulation and monitoring of environmental xenobiotics in fish. , 1987, Environmental health perspectives.

[184] J. Poirier,et al. ECOGENETICS OF PARKINSON'S DISEASE: 4-HYDROXYLATION OF DEBRISOQUINE , 1985, The Lancet.

[185] J. Idle,et al. A population and familial study of the defective alicyclic hydroxylation of debrisoquine among Egyptians. , 1979, Xenobiotica; the fate of foreign compounds in biological systems.

[186] A. Fulco,et al. Coding nucleotide, 5' regulatory, and deduced amino acid sequences of P-450BM-3, a single peptide cytochrome P-450:NADPH-P-450 reductase from Bacillus megaterium. , 1989, The Journal of biological chemistry.

[187] Y. Fujii‐Kuriyama,et al. Functional expression of microsomal and mitochondrial cytochrome P-450 (d and SCC) in COS-7 cells from cloned cDNA. , 1990, Cell structure and function.

[188] A. Bender. Drug sensitivity in the elderly , 1979 .

[189] U. Meyer,et al. Mephenytoin-type polymorphism of drug oxidation: purification and characterization of a human liver cytochrome P-450 isozyme catalyzing microsomal mephenytoin hydroxylation. , 1986, Biochimica et biophysica acta.

[190] I. Turko,et al. Cross-linking studies of steroidogenic electron transfer: covalent complex of adrenodoxin reductase with adrenodoxin. , 1985, Biochimica et biophysica acta.

[191] F. Oesch,et al. Genetically engineered V79 Chinese hamster cell expression of purified cytochrome P-450IIB1 monooxygenase activity. , 1989, Journal of biochemical toxicology.

[192] A. Seidel,et al. Genetically engineered V79 Chinese hamster cells for stable expression of human cytochrome P450IA2. , 1992, European journal of pharmacology.

[193] P. Sinclair,et al. Chlorinated biphenyls induce cytochrome P450IA2 and uroporphyrin accumulation in cultures of mouse hepatocytes. , 1990, Archives of biochemistry and biophysics.

[194] V. Stevens,et al. Cytochrome P-450scc: enzymology, and the regulation of intramitochondrial cholesterol delivery to the enzyme. , 1984, Endocrine research.

[195] Antigenic Crossreactivity between Bacterial and Plant Cytochrome P-450 Monoxygenases. , 1989, Plant physiology.

[196] Y. Fujii‐Kuriyama,et al. Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[197] P. Thomas,et al. Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction. , 1981, The Journal of biological chemistry.

[198] G. Johansson,et al. Effect of cholestyramine and diet on hydroxylations in the biosynthesis and metabolism of bile acids. , 1970, European journal of biochemistry.

[199] B. Moorthy,et al. Amino‐terminal sequence homology of two chick kidney mitochondrial proteins immunoisolated with monoclonal antibodies to the cytochrome P450 of 25‐hydroxyvitamin D3‐1α‐hydroxylase , 1991 .

[200] I. Hällström. Genetic regulation of the cytochrome P-450 system in Drosophila melanogaster. II. Localization of some genes regulating cytochrome P-450 activity. , 1985, Chemico-biological interactions.

[201] T. Iyanagi,et al. Interaction between NADPH-cytochrome P-450 reductase and cytochrome P-450 in the membrane of phosphatidylcholine vesicles. , 1979, Biochimica et biophysica acta.

[202] Age-Related Changes in Sensitivity to Environmental Chemicals , 1990 .

[203] P. Thomas,et al. Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes. , 1987, Biochemistry.

[204] Y. Fujii‐Kuriyama,et al. Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[205] E. Wu,et al. Lateral diffusion of cytochrome P-450 in phospholipid bilayers. , 1984, Biochemistry.

[206] H. Coon,et al. Regulation of aryl hydrocarbon hydroxylase in intraspecific hybrids of human, mouse, and hamster cells. , 1972, Proceedings of the National Academy of Sciences of the United States of America.

[207] B. Grandchamp,et al. Molecular genetics of porphyrias. , 1990, Annals of medicine.

[208] J. Schenkman,et al. Regioselective hydroxylation of prostaglandins by constitutive forms of cytochrome P-450 from rat liver: formation of a novel metabolite by a female-specific P-450. , 1988, Archives of biochemistry and biophysics.

[209] T. Ogishima,et al. An improved method for assay of cholesterol 7α-hydroxylase activity , 1986 .

[210] B. Summers,et al. Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease , 1992, The Lancet.

[211] T. Poulos,et al. High-resolution crystal structure of cytochrome P450cam. , 1987, Journal of molecular biology.

[212] H. DeLuca,et al. Characteristics of the rat liver microsomal enzyme system converting cholecalciferol into 25-hydroxycholecalciferol. Evidence for the participation of cytochrome p-450. , 1979, The Biochemical journal.

[213] J. Halpert. Multiplicity of steroid-inducible cytochromes P-450 in rat liver microsomes. , 1988, Archives of biochemistry and biophysics.

[214] M. J. Coon,et al. Membrane topology of microsomal cytochrome P-450: saturation transfer EPR and freeze-fracture electron microscopy studies. , 1990, Biochemical and biophysical research communications.

[215] J. Darnell,et al. Persistence of liver-specific messenger RNA in cultured hepatocytes: different regulatory events for different genes , 1987, The Journal of cell biology.

[216] M. Tevini,et al. Lipids and Lipid Polymers in Higher Plants , 1977, Springer Berlin Heidelberg.

[217] P. Thomas,et al. Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. , 1984, The Journal of biological chemistry.

[218] U. Meyer,et al. MPTP, the neurotoxin inducing Parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufI, P450db1) catalyzing debrisoquine 4-hydroxylation. , 1987, Biochemical and biophysical research communications.

[219] J. Schenkman,et al. Studies on Three Microsomal Electron Transfer Enzyme Systems: Effects of Alteration of Component Enzyme Levels in Vivo and in Vitro , 1975 .

[220] L. Poellinger,et al. Polyanionic-binding properties of the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. A comparison with the glucocorticoid receptor. , 1986, The Journal of biological chemistry.

[221] T. Wolff,et al. Presence of cytochrome P-450- and cytochrome P-448-dependent monooxygenase functions in hepatoma cell lines. , 1980, Biochemical and biophysical research communications.

[222] J. Schenkman,et al. Relationship between phosphorylation and cytochrome P450 destruction. , 1990, Archives of biochemistry and biophysics.

[223] E. Bresnick,et al. Further characterization of the polycyclic aromatic hydrocarbon binding properties of the 4S protein. , 1986, Archives of biochemistry and biophysics.

[224] J. Connell,et al. Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[225] E. Bresnick,et al. Differences in the binding of 3-methylcholanthrene and phenobarbital to rat liver cytosolic and nuclear protein fractions. , 1981, Archives of biochemistry and biophysics.

[226] J. Trudell,et al. Association of cytochrome b5 and cytochrome P-450 reductase with cytochrome P-450 in the membrane of reconstituted vesicles. , 1982, The Journal of biological chemistry.

[227] R. Kato,et al. Polymorphism in hydroxylation of mephenytoin and hexobarbital stereoisomers in relation to hepatic P‐450 human‐2 , 1990, Clinical pharmacology and therapeutics.

[228] D. Nebert,et al. Human CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLP. , 1991, American journal of human genetics.

[229] J. Gustafsson,et al. Regulation and substrate specificity of a steroid sulfate-specific hydroxylase system in female rat liver microsomes. , 1975, The Journal of biological chemistry.

[230] J. Yates,et al. A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus , 1985, Molecular and cellular biology.

[231] O. Takikawa,et al. Properties of an adrenal cytochrome P-450 (P-450SCC) for the side chain cleavage of cholesterol. , 1978, Archives of biochemistry and biophysics.

[232] G. Kochs,et al. Enzymic synthesis of isoflavones. , 1986, European journal of biochemistry.

[233] I. Benveniste,et al. Purification and characterization of the NADPH-cytochrome P-450 (cytochrome c) reductase from higher-plant microsomal fraction. , 1986, The Biochemical journal.

[234] O. Gotoh,et al. Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[235] W. Miller,et al. Structure of a bovine gene for P-450c21 (steroid 21-hydroxylase) defines a novel cytochrome P-450 gene family. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[236] E. Lipson,et al. The role of mitochondrial cytochrome P-450 from bovine adrenal cortex in side chain cleavage of 20S,22R-dihydroxycholesterol. , 1975, The Journal of biological chemistry.

[237] T. Poulos,et al. Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex. , 1989, Biochemistry.

[238] U. Meyer,et al. The human CYP2D locus associated with a common genetic defect in drug oxidation: a G1934----A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3' splice recognition site. , 1990, American journal of human genetics.

[239] I. Roots,et al. Debrisoquine hydroxylation phenotype, acetylation phenotype, and ABO blood groups as genetic host factors of lung cancer risk. , 1988, Klinische Wochenschrift.

[240] R. Kraft,et al. Electrostatic interactions between cytochrome P-450 LM2 and NADPH-cytochrome P-450 reductase. , 1988, Biomedica biochimica acta.

[241] A. Cederbaum,et al. Rapid decrease of cytochrome P‐450IIE1 in primary hepatocyte culture and its maintenance by added 4‐methylpyrazole , 1990, Hepatology.

[242] T. Nishino,et al. Altered cytochrome P-450 in a yeast mutant blocked in demethylating C-32 of lanosterol. , 1983, The Journal of biological chemistry.

[243] H. Rennert,et al. Generation of regulatory oxysterols: 26-hydroxylation of cholesterol by ovarian mitochondria. , 1990, Endocrinology.

[244] M. Magnuson,et al. An alternate promoter in the glucokinase gene is active in the pancreatic beta cell. , 1989, The Journal of biological chemistry.

[245] R. Takayanagi,et al. Relative inactivation of steroidogenic enzyme activities of in vitro vitamin E-depleted human adrenal microsomes by lipid peroxidation. , 1986, Endocrinology.

[246] M. J. Coon,et al. cDNA and derived amino acid sequence of rabbit nasal cytochrome P450NMb (P450IIG1), a unique isozyme possibly involved in olfaction. , 1991, Archives of biochemistry and biophysics.

[247] B. Foster,et al. Biotransformation of aryl alkylamines by Cunninghamella bainieri. , 1989, Xenobiotica; the fate of foreign compounds in biological systems.

[248] K. Watanabe,et al. Cytochrome P-45011 beta and P-450scc in adrenal cortex: zonal distribution and intramitochondrial localization by the horseradish peroxidase-labeled antibody method. , 1982, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[249] C. Slaughter,et al. Cloning and regulation of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis. , 1990, The Journal of biological chemistry.

[250] P. Watkins,et al. Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat. , 1986, Molecular pharmacology.

[251] M. J. Coon,et al. Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation. , 1969, Biochemical and biophysical research communications.

[252] E. Chambaz,et al. Adrenocortical cytochrome P-450 responsible for cholesterol side chain cleavage (P-450scc) is phosphorylated by the calcium-activated, phospholipid-sensitive protein kinase (protein kinase C). , 1984, Biochemical and biophysical research communications.

[253] M. Noshiro,et al. Molecular cloning of cDNA for cholesterol 7 alpha-hydroxylase from rat liver microsomes. Nucleotide sequence and expression. , 1989, FEBS letters.

[254] H. Stiel,et al. Distance between lysine 384 and heme of cytochrome P-450 LM2 (P-450 IIB4) studied by fluorescence energy transfer measurements. , 1989, Biochemical and biophysical research communications.

[255] Y. Fujii‐Kuriyama,et al. Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements. , 1987, Nucleic acids research.

[256] J. Rifkind,et al. Age-related changes in the iron spin state of testosterone-binding rat liver microsomal cytochromes P-450. , 1989, Biochemical and biophysical research communications.

[257] M. Tsubaki,et al. Inhibition of electron transfer from adrenodoxin to cytochrome P-450scc by chemical modification with pyridoxal 5'-phosphate: identification of adrenodoxin-binding site of cytochrome P-450scc. , 1989, Biochemistry.

[258] H. Popper,et al. Effect of cyclic AMP on the phenobarbital induced increase in cytochrome P-450 and hypertrophy of the endoplasmic reticulum of the rat liver. , 1975, Advances in experimental medicine and biology.

[259] D. Waxman,et al. Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. , 1985, Biochemistry.

[260] H. Kleinman,et al. Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix , 1988, Journal of cellular physiology.

[261] C. Blais,et al. Ecdysone 20-hydroxylation in imaginal wing discs of Pieris brassicae (lepidoptera): Correlations with ecdysone and 20-hydroxyecdysone titers in pupae , 1986 .

[262] S. Imaoka,et al. Hepatic and renal cytochrome P-450s in spontaneously hypertensive rats. , 1991, Biochimica et biophysica acta.

[263] J. Cashman,et al. Epoxy derivatives of arachidonic acid are potent stimulators of prolactin secretion. , 1987, Neuroendocrinology.

[264] S. Sassa,et al. Metabolism of estradiol in liver cell culture. Differential responses of C-2 and C-16 oxidations to drugs and other chemicals that induce selective species of cytochrome P-450. , 1983, The Journal of clinical investigation.

[265] C. Lamb,et al. Biophysical and enzymological studies upon the interaction of trans-cinnamic acid with higher plant microsomal cytochromes P-450. , 1977, European journal of biochemistry.

[266] J. Lemann,et al. The importance of phosphate in regulating plasma 1,25-(OH)2-vitamin D levels in humans: studies in healthy subjects in calcium-stone formers and in patients with primary hyperparathyroidism. , 1977, The Journal of clinical endocrinology and metabolism.

[267] I. Z. Ades,et al. Coordinate elevations of liver delta-aminolevulinate synthase and cytochrome P-450 RNA by phenobarbital in chicken embryos: the effects of heme. , 1989, The International journal of biochemistry.

[268] R. Gray,et al. Solubilization and reconstitution of kidney 25-hydroxyvitamin D3 1 alpha- and 24-hydroxylases from vitamin D-replete pigs. , 1989, The Biochemical journal.

[269] S. Groh,et al. Electron spin echo modulation demonstrates P-450scc complexation , 1983 .

[270] D. Weaver,et al. The identity and nuclear uptake of a cytosolic binding protein for 3-methylcholanthrene. , 1980, Archives of biochemistry and biophysics.

[271] S. Granick,et al. The induction in vitro of the synthesis of delta-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals. , 1966, The Journal of biological chemistry.

[272] F. Guengerich,et al. Interaction of liver microsomal cytochrome P-450 and NADPH-cytochrome P-450 reductase in the presence and absence of lipid. , 1984, The Journal of biological chemistry.

[273] T. Kamataki,et al. Neonatal testosterone imprinting of hepatic microsomal drug metabolism and a male-specific form of cytochrome P-450 in the rat. , 1984, Journal of biochemistry.

[274] M. Sari,et al. Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae. , 1990, Biochemistry.

[275] J. Gustafsson,et al. Differential expression of the cytochrome P-450c and P-450d genes in the rat ventral prostate and liver. , 1988, Cancer research.

[276] M. Ingelman-Sundberg,et al. Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system , 1990, Neuroscience.

[277] J. Gustafsson,et al. Endocrine regulation of cytochrome P-450 in the rat brain and pituitary gland. , 1989, The Journal of endocrinology.

[278] C. Levene. Histology—a Text and Atlas , 1976 .

[279] R. Feyereisen,et al. Enzymic synthesis of juvenile hormone in locust corpora allata: evidence for a microsomal cytochrome P-450 linked methyl farnesoate epoxidase. , 2005, European journal of biochemistry.

[280] P. Thomas,et al. Isozyme specificity of testosterone 7 alpha-hydroxylation in rat hepatic microsomes: is cytochrome P-450a the sole catalyst? , 1987, Archives of biochemistry and biophysics.

[281] P. Watkins,et al. Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p. , 1985, Biochemistry.

[282] Richard Graham Knowles,et al. Constitutive and inducible nitric oxide synthases incorporate molecular oxygen into both nitric oxide and citrulline. , 1991, The Journal of biological chemistry.

[283] K. Morohashi,et al. Structural analysis of multiple bovine P-450(11 beta) genes and their promoter activities. , 1990, Journal of biochemistry.

[284] S. Takemori,et al. Purification and immunochemical characterization of the two adrenal cortex mitochondrial cytochrome P-450-proteins. , 1978, Archives of biochemistry and biophysics.

[285] W. Fitch. Distinguishing homologous from analogous proteins. , 1970, Systematic zoology.

[286] J. Schenkman,et al. The many roles of cytochrome b-5 in hepatic microsomes. , 1976, Life sciences.

[287] M. J. Coon,et al. The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. , 1991, DNA and cell biology.

[288] D. Breimer,et al. Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects. , 1988, Biochemical pharmacology.

[289] K. Einarsson. On the Properties of the 12α‐Hydroxylase in Cholic Acid Biosynthesis , 1968 .

[290] J. Gustafsson,et al. Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[291] A Isaksson,et al. Exposure to organic solvents. A cross-sectional epidemiologic investigation on occupationally exposed care and industrial spray painters with special reference to the nervous system. , 1980, Scandinavian journal of work, environment & health.

[292] H. Ohkawa,et al. Expression in Saccharomyces cerevisiae of chimeric cytochrome P450 cDNAs constructed from cDNAs for rat cytochrome P450c and P450d. , 1987, DNA.

[293] A. Brøgger,et al. Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. , 1991, Pharmacogenetics.

[294] J. Richards,et al. Aromatase cytochrome P450 in rat ovarian granulosa cells before and after luteinization: adenosine 3',5'-monophosphate-dependent and independent regulation. Cloning and sequencing of rat aromatase cDNA and 5' genomic DNA. , 1990, Molecular endocrinology.

[295] D. Nebert,et al. Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene. , 1979, The Journal of biological chemistry.

[296] W. Kühn‐Velten,et al. Thermodynamics and modulation of progesterone microcompartmentation and hydrophobic interaction with cytochrome P450XVII based on quantification of local ligand concentrations in a complex multi-component system. , 1991, European journal of biochemistry.

[297] M. Işcan,et al. Comparative studies of sheep liver and lung microsomal aniline 4-hydroxylase. , 1983, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

[298] R. Tukey,et al. Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6. , 1985, DNA.

[299] H. Rees,et al. Reversible activation-inactivation of mitochondrial ecdysone 20-mono-oxygenase: A possible role for phosphorylation-dephosphorylation , 1988 .

[300] R. Hoover,et al. Human debrisoquine hydroxylase gene polymorphisms in cancer patients and controls. , 1990, Carcinogenesis.

[301] P. Sinclair,et al. Inhibition of uroporphyrinogen decarboxylase activity. The role of cytochrome P-450-mediated uroporphyrinogen oxidation. , 1990, The Biochemical journal.

[302] R. O'Connor,et al. cDNA cloning and analysis of chick-embryo-liver cytochrome P-450 mRNA induced by porphyrinogenic drugs. , 1982, European journal of biochemistry.

[303] R. Peterson,et al. Effects of a hormone-supplemented medium on cytochrome P-450 content and mono-oxygenase activities of rat hepatocytes in primary culture. , 1980, Biochemical pharmacology.

[304] Robert Vestal. Pharmacology and Aging , 1982, Journal of the American Geriatrics Society.

[305] Y. Fujii‐Kuriyama,et al. The 5'-flanking region of the human P-450(SCC) gene shows responsiveness to cAMP-dependent regulation in a transient gene-expression system of Y-1 adrenal tumor cells. , 1988, European journal of biochemistry.

[306] J. Schenkman,et al. Purification to homogeneity and enzymological characterization of a functional covalent complex composed of cytochromes P-450 isozyme 2 and b5 from rabbit liver. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[307] U. Meyer,et al. Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification , 1990, The Lancet.

[308] S. Wrighton,et al. Synthesis and degradation of 3-methylcholanthrene-inducible cytochromes P-450 and their mRNAs in primary monolayer cultures of adult rat hepatocytes. , 1985, Archives of biochemistry and biophysics.

[309] J. Schenkman,et al. Evidence of binary complex formations between cytochrome P-450, cytochrome b5, and NADPH-cytochrome P-450 reductase of hepatic microsomes. , 1986, Biochemical and biophysical research communications.

[310] J. Gustafsson,et al. Age dependent expression of cytochrome P-450b and metabolism of the potent carcinogen 2-nitrofluorene in the rat lung. , 1988, Carcinogenesis.

[311] D. Williams,et al. Benzo[a]pyrene-hydroxylase catalyzed by purified isozymes of cytochrome P-450 from beta-naphthoflavone-fed rainbow trout. , 1984, Biochemical pharmacology.

[312] S. Orrenius,et al. Xenobiotic metabolism and enzyme induction in isolated rat intestinal microsomes. , 1976, Drug metabolism and disposition: the biological fate of chemicals.

[313] C. Mendelson,et al. Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues. , 1991, Molecular endocrinology.

[314] R. Gasser,et al. Primary Structures and Regulation of Cytochrome P-450 Isozymes 2 (IIB) And 5 (IVB) and the Flavin-Containing Monooxygenase in Rabbit Liver and Lung , 1991 .

[315] I. Rowland,et al. Developmental changes in hepatic activation of dietary mutagens by mice. , 1989, Chemico-biological interactions.

[316] C. Lieber,et al. New pathway for retinol metabolism in liver microsomes. , 1985, The Journal of biological chemistry.

[317] I. Phillips,et al. Quantification of NADPH: cytochrome P-450 reductase in liver microsomes by a specific radioimmunoassay technique. , 1983, The Biochemical journal.

[318] W L Miller,et al. SEQUENCES OF INTEREST: Homologous Sequences in Steroidogenic Enzymes, Steroid Receptors and a Steroid Binding Protein Suggest a Consensus Steroid-Binding Sequence , 1988 .

[319] F. Kiefer,et al. Phenobarbital induces cytochrome P-450- and cytochrome P-448-dependent monooxygenases in rat hepatoma cells. , 1984, Chemico-biological interactions.

[320] J. Gustafsson,et al. Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[321] C. S. Yang,et al. Roles of pituitary hormones in the regulation of hepatic cytochrome P450IIE1 in rats and mice. , 1990, Archives of biochemistry and biophysics.

[322] M. Fujita,et al. Properties of a Mixed Function Oxygenase Catalyzing Ipomeamarone 15-Hydroxylation in Microsomes from Cut-Injured and Ceratocystis fimbriata-Infected Sweet Potato Root Tissues. , 1982, Plant physiology.

[323] T. Südhof,et al. Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene. , 1987, The Journal of biological chemistry.

[324] T. Masuko,et al. Induction of cytochrome P-448 isozyme(s) in primary cultured rat hepatocytes by drugs which induce different isozymes in vivo. , 1987, Biochemical and biophysical research communications.

[325] C. Wolf,et al. Purification and structural comparison of pulmonary and hepatic cytochrome P-450 from rabbits. , 1980, Biochimica et biophysica acta.

[326] E. Bresnick,et al. 3-Methylcholanthrene-induced expression of the cytochrome P-450c gene. , 1985, Archives of biochemistry and biophysics.

[327] R. Feyereisen,et al. Ecdysterone biosynthesis: a microsomal cytochrome-P-450-linked ecdysone 20-monooxygenase from tissues of the African migratory locust. , 1978, European journal of biochemistry.

[328] T. Gaździk,et al. [Effect of age on the activity of hepatic mixed function oxidases in female rats]. , 1988, Medycyna pracy.

[329] J. Schenkman,et al. Differences in the mechanism of functional interaction between NADPH-cytochrome P-450 reductase and its redox partners. , 1986, Molecular pharmacology.

[330] R. Estabrook,et al. Isolation from adrenal cortex of a nonheme iron protein and a flavoprotein functional as a reduced triphosphopyridine nucleotide-cytochrome P-450 reductase , 1966 .

[331] Y. Yoshida. Cytochrome P450 of fungi: primary target for azole antifungal agents. , 1988, Current topics in medical mycology.

[332] L. Birnbaum,et al. Induction of hepatic mixed function oxidases in senescent rodents—II. Effect of polychlorinated biphenyls , 1978, Experimental Gerontology.

[333] V. Russell,et al. Evidence that estradiol-2/4-hydroxylase activities in rat hypothalamus and hippocampus differ qualitatively and involve multiple forms of P-450: ontogenetic and inhibition studies. , 1985, Journal of steroid biochemistry.

[334] D. Waxman,et al. Hormonal regulation of levels of the messenger RNA encoding hepatic P450 2c (IIC11), a constitutive male-specific form of cytochrome P450. , 1990, Molecular endocrinology.

[335] C. Wolf,et al. The rabbit pulmonary monooxygenase system. partial structural characterization of the cytochrome P-450 components and comparison to the hepatic cytochrome P-450. , 1981, The Journal of biological chemistry.

[336] M. Ingelman-Sundberg,et al. Reduction of cytochrome P-450 LM2 by NADPH in reconstituted phospholipid vesicles is dependent on membrane charge. , 1983, European journal of biochemistry.

[337] H. Strobel,et al. The drug and carcinogen metabolism system of rat colon microsomes. , 1978, Archives of biochemistry and biophysics.

[338] H Wachter,et al. Brain nitric oxide synthase is a biopterin‐ and flavin‐containing multi‐functional oxido‐reductase , 1991, FEBS letters.

[339] F. De Matteis,et al. Increased oxidation of uroporphyrinogen by an inducible liver microsomal system. Possible relevance to drug-induced uroporphyria. , 1988, The Biochemical journal.

[340] H. Ochi,et al. Studies on the steroid hydroxylation system in adrenal cortex microsomes. Purification and characterization of cytochrome P-450 specific for steroid C-21 hydroxylation. , 1980, The Journal of biological chemistry.

[341] 青山由利,et al. Role of the 8-double bond of lanosterol in the enzyme-substrate interaction of cytochrome P-450₁₄DM (lanosterol 14α-demethylase) , 1989 .

[342] R. Hayes,et al. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. , 1992, Pharmacogenetics.

[343] J. Gustafsson,et al. Transcriptional and posttranscriptional regulation of sexually differentiated rat liver cytochrome P-450 by growth hormone. , 1989, Molecular endocrinology.

[344] I. Meyer,et al. Specificity of steroid binding to testicular microsomal cytochrome P-450. Relation of steroid structure to type-I spectral responses after correction for hydrophobic association with the membrane. , 1989, Journal of steroid biochemistry.

[345] H. Remmer,et al. Comparison of microsomal drug hydroxylation in lung and liver of various species. , 1970, Research communications in chemical pathology and pharmacology.

[346] Y. Murooka,et al. An operon containing the genes for cholesterol oxidase and a cytochrome P-450-like protein from a Streptomyces sp , 1990, Journal of bacteriology.

[347] L. Birnbaum,et al. Age‐Related Changes in Carcinogen Metabolism , 1987, Journal of the American Geriatrics Society.

[348] A. Brownie,et al. Steroidogenesis-activator polypeptide isolated from a rat Leydig cell tumor. , 1987, Science.

[349] M. Dufau,et al. Rat testis P-45017α cDNA: The deduced amino acid sequence, expression and secondary structural configuration , 1988 .

[350] R. Kato,et al. Purification and characterization of four catalytically active testosterone 6 beta-hydroxylase P-450s from rat liver microsomes: comparison of a novel form with three structurally and functionally related forms. , 1990, Journal of biochemistry.

[351] M. J. Coon,et al. Olefin formation in the oxidative deformylation of aldehydes by cytochrome P-450. Mechanistic implications for catalysis by oxygen-derived peroxide , 1991 .

[352] H Koga,et al. Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[353] C. Plopper,et al. Distribution of cytochrome P-450 monoxygenase enzymes in the nasal mucosa of hamster and rat. , 1991, The American journal of anatomy.

[354] 岡本達也,et al. ハムスター肺のAryl Hydrocarbon Hydroxylaseについて , 1974 .

[355] D. Bendall,et al. Cytochrome components of plant microsomes. , 1975, European journal of biochemistry.

[356] H. Taniguchi,et al. Phospholipid bilayer membranes play decisive roles in the cytochrome P-450-dependent monooxygenase system , 1988, Journal of Cancer Research and Clinical Oncology.

[357] P. Churchill,et al. Topological studies of the steroid hydroxylase complexes in bovine adrenocortical mitochondria. , 1978, The Journal of biological chemistry.

[358] G. Jänig,et al. Role of lipid in the electron transfer between NADPH-cytochrome P-450 reductase and cytochrome P-450 from mammalian liver cells. , 1989, Xenobiotica; the fate of foreign compounds in biological systems.

[359] F. Guengerich,et al. Characterization of a rat liver cytochrome P-450UT-H cDNA clone and comparison of mRNA levels with catalytic activity. , 1987, Molecular pharmacology.

[360] G. Siest,et al. Hydroxylation of Debrisoquine Using Perfused Liver Isolated from Sprague Dawley and DA Rats: Comparison With In‐vivo Results , 1988, The Journal of pharmacy and pharmacology.

[361] D. Nebert,et al. Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation. , 1990, Trends in genetics : TIG.

[362] I. Turko,et al. Cross-linking studies of the cholesterol hydroxylation system from bovine adrenocortical mitochondria. , 1989, Biochimica et biophysica acta.

[363] J. Trudell,et al. Reconstitution of cytochrome P-450 and cytochrome P-450 reductase into phosphatidylcholine-phosphatidylethanolamine bilayers: characterization of structure and metabolic activity. , 1979, Molecular pharmacology.

[364] M. Favus,et al. Evidence that blood ionized calcium can regulate serum 1,25(OH)2D3 independently of parathyroid hormone and phosphorus in the rat. , 1985, The Journal of clinical investigation.

[365] N. Harada,et al. Mouse liver testosterone 16 alpha-hydroxylase (cytochrome P-450(16) alpha). Purification, regioselectivity, stereospecificity, and immunochemical characterization. , 1984, The Journal of biological chemistry.

[366] S. Sligar,et al. Molecular Recognition in Cytochrome P-450: Alteration of Regioselective Alkane Hydroxylation via Protein Engineering. , 1989 .

[367] M. Chiba,et al. Age-associated alteration in imipramine metabolism is position selective. , 1986, Biochemical pharmacology.

[368] R. Kato,et al. Cytochrome P450 in livers of diabetic rats: regulation by growth hormone and insulin. , 1989, Archives of biochemistry and biophysics.

[369] H. DeLuca,et al. Subcellular location of rat liver calciferol-25-hydroxylase. , 1974, Archives of biochemistry and biophysics.

[370] R. Santen,et al. Inborn error in the terminal step of aldosterone biosynthesis. Corticosterone methyl oxidase tpe II deficiency in a North American pedigree. , 1980, The New England journal of medicine.

[371] D. Jacobowitz,et al. Immunohistochemical localization of cytochrome P-450 in rat brain , 1987, Neuroscience.

[372] C. Langman,et al. Evidence for calcium-dependent control of 1,25-dihydroxyvitamin D3 production by rat kidney proximal tubules. , 1986, The Journal of biological chemistry.

[373] M. J. Coon,et al. Organization and differential expression of two highly similar genes in the rabbit alcohol-inducible cytochrome P-450 subfamily. , 1988, The Journal of biological chemistry.

[374] P. R. Peacock. Chemically induced tumors of fowls. , 1958, Advances in cancer research.

[375] U. Matern,et al. Differential response of cultured parsley cells to elicitors from two non-pathogenic strains of fungi. Microsomal conversion of (+)marmesin into psoralen. , 1986, European journal of biochemistry.

[376] M. Höhne,et al. Regulation of cytochrome P‐450 CYPIA1 gene expression and protooncogene expression by growth factors in primary hepatocytes , 1990, FEBS letters.

[377] A. Rösler,et al. The nature of the defect in a salt-wasting disorder in Jews of Iran. , 1977, The Journal of clinical endocrinology and metabolism.

[378] E. Krebs,et al. Phosphorylation-dephosphorylation of enzymes. , 1979, Annual review of biochemistry.

[379] A. Lindenmayer,et al. CYTOCHROMES AND OTHER PIGMENTS OF BAKER'S YEAST GROWN AEROBICALLY AND ANAEROBICALLY. , 1964, Biochimica et biophysica acta.

[380] D. Waxman,et al. Posttranslational modification of hepatic cytochrome P-450. Phosphorylation of phenobarbital-inducible P-450 forms PB-4 (IIB1) and PB-5 (IIB2) in isolated rat hepatocytes and in vivo. , 1989, Biochemistry.

[381] B. May,et al. Hemin administration to rats reduces levels of hepatic mRNAs for phenobarbitone-inducible enzymes. , 1990, Molecular pharmacology.

[382] J. Lambeth,et al. Cytochrome P-450scc-substrate interactions. Role of the 3 beta- and side chain hydroxyls in binding to oxidized and reduced forms of the enzyme. , 1986, The Journal of biological chemistry.

[383] A. Boobis,et al. Debrisoquine oxidation phenotype and susceptibility to lung cancer. , 1990, British journal of clinical pharmacology.

[384] F. Gonzalez,et al. The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. , 1990, Biochemistry.

[385] A. Okey,et al. Equivalent molecular mass of cytosolic and nuclear forms of Ah receptor from Hepa-1 cells determined by photoaffinity labeling with 2,3,7,8-[3H]tetrachlorodibenzo-p-dioxin. , 1990, Biochemical and biophysical research communications.

[386] O. Mcbride,et al. Identification of a new P450 expressed in human lung: complete cDNA sequence, cDNA-directed expression, and chromosome mapping. , 1989, Biochemistry.

[387] K. Iwahashi,et al. Studies of the immunohistochemical and biochemical localization of the cytochrome P-450scc-linked monooxygenase system in the adult rat brain. , 1990, Biochimica et biophysica acta.

[388] P. Sinclair,et al. Effect of interleukin 6 on phenobarbital induction of cytochrome P-450IIB in cultured rat hepatocytes. , 1991, Biochemical and biophysical research communications.

[389] M. J. Coon,et al. Properties of electrophoretically homogeneous constitutive forms of liver microsomal cytochrome P-450. , 1981, The Journal of biological chemistry.

[390] R. Kato,et al. Role of growth hormone in modulating the constitutive and phenobarbital-induced levels of two P-450(6)beta (testosterone 6 beta-hydroxylase) mRNAs in rat livers. , 1989, Journal of biochemistry.

[391] B. Cooper,et al. Rat liver cholesterol 7 alpha-hydroxylase. Modulation of enzyme activity by changes in phosphorylation state. , 1982, The Journal of biological chemistry.

[392] J. Peterson,et al. Purification and properties of putidaredoxin reductase. , 1983, The Journal of biological chemistry.

[393] W. Staib,et al. Age-dependence of the rat Leydig cell and Sertoli cell function. Development of the peripheral testosterone level and its relation to mitochondrial and microsomal cytochromes P-450 and to androgen-binding protein. , 1987, Acta endocrinologica.

[394] J. Meites,et al. Growth hormone secretory patterns in young, middle-aged and old female rats. , 1987, Neuroendocrinology.

[395] M. Henry. Mode of action of the fungicide flusilazole in ustilago maydis , 1990 .

[396] J. Goldstein,et al. Oxidation of uroporphyrinogen by methylcholanthrene-induced cytochrome P-450. Essential role of cytochrome P-450d. , 1989, The Biochemical journal.

[397] P. Srivastava,et al. Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae. , 1989, Biochemistry.

[398] S. Usanov,et al. Chapter 1. Cytochrome P-450 Dependent Pathways of the Biosynthesis of Steroid Hormones , 1990, Molecular mechanisms of adrenal steroidogenesis and aspects of regulation and application.

[399] M. Jackson,et al. Induction of UDP-glucuronyl transferase mRNA in embryonic chick livers by phenobarbital. , 1986, Biochemical Pharmacology.

[400] D. Stevenson,et al. Synthesis of 19-functionalised derivatives of 16α-hydroxy-testosterone: mechanistic studies on oestriol biosynthesis , 1985 .

[401] O. Gotoh,et al. Titration of mRNAs for cytochrome P-450c and P-450d under drug-inductive conditions in rat livers by their specific probes of cloned DNAs. , 1984, The Journal of biological chemistry.

[402] H. Murakami,et al. Expression of rat NADPH-cytochrome P-450 reductase cDNA in Saccharomyces cerevisiae. , 1986, DNA.

[403] M. Weirich,et al. Cytochrome P-450-catalyzed formation of 20-hydroxy-ecdysone in larval housefly mitochondria. , 1990, Biochemical and biophysical research communications.

[404] R. Kraft,et al. A simple determination of the sideness of the NH2-terminus in the membrane bound cytochrome P-450 LM2. , 1988, Biochemistry international.

[405] C. Roselli,et al. Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system. , 1985, Endocrinology.

[406] S. Aquilonius,et al. Poor hydroxylator phenotypes of debrisoquine and S-mephenytoin are not over-represented in a group of patients with Parkinson's disease. , 1990, British journal of clinical pharmacology.

[407] M. Karin,et al. Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene , 1984, Nature.

[408] P. Magee,et al. Differential effects on the metabolism of dimethylnitrosamine and aflatoxin B1 by hepatic microsomes from senescent rats. , 1986, Cancer letters.

[409] L. Balant,et al. The genetic control of bufuralol metabolism in man. , 1982, European journal of drug metabolism and pharmacokinetics.

[410] R. Kato,et al. Modulation of hepatic level of microsomal testosterone 7 alpha-hydroxylase, P-450a (P450IIA), by thyroid hormone and growth hormone in rat liver. , 1990, Journal of biochemistry.

[411] M. Drezner,et al. Variable phosphate-mediated regulation of vitamin D metabolism in the murine hypophosphatemic rachitic/osteomalacic disorders. , 1991, Endocrinology.

[412] L. Rutzky,et al. Human colon adenocarcinoma cells. III. In vitro organoid expression and carcinoembryonic antigen kinetics in hollow fiber culture. , 1979, Journal of the National Cancer Institute.

[413] J. Gustafsson,et al. Sex steroid induced changes in hepatic enzymes. , 1983, Annual review of physiology.

[414] P. Bentley,et al. Studies on the mechanism of induction of microsomal cytochrome P452 and peroxisomal bifunctional enzyme mRNAs by nafenopin in primary cultures of adult rat hepatocytes. , 1991, Biochemical pharmacology.

[415] S. Yu. Consequences of Induction of Foreign Compound-Metabolizing Enzymes in Insects , 1986 .

[416] A. Goksøyr,et al. Initial purification and characterization of hepatic microsomal cytochrome P-450 from BNF-treated perch (Perca fluviatilis). , 1991, Comparative biochemistry and physiology. B, Comparative biochemistry.

[417] J. Buster,et al. Radioimmunoassay of plasma pregnenolone. , 1973, The Journal of clinical endocrinology and metabolism.

[418] U. Meyer,et al. Polymerase chain reaction-directed identification, cloning, and quantification of human CYP2C18 mRNA. , 1991, Molecular pharmacology.

[419] C. Tsai-Morris,et al. Gonadotropic regulation of aromatase activity in the adult rat testis. , 1984, Annals of the New York Academy of Sciences.

[420] C. Chen,et al. Primary structure of the cytochrome P450 lanosterol 14 alpha-demethylase gene from Candida tropicalis. , 1988, DNA.

[421] L. Sokoloff,et al. STUDIES ON THE MECHANISM OF METHYLCHOLANTHRENE INDUCTION OF ENZYME ACTIVITIES OF RAT LIVER. I. AMINO ACID INCORPORATION IN RAT-LIVER HOMOGENATES. , 1964, Biochimica et biophysica acta.

[422] J. Crivello,et al. Nitrosodiethylamine metabolism in the viviparous fish Poeciliopsis: evidence for the existence of liver P450pj activity and expression. , 1991, Carcinogenesis.

[423] R. Morton,et al. Genes controlling malathion resistance in a laboratory-selected population of Drosophila melanogaster. , 1988, Genome.

[424] H. Vanden Bossche. Biochemical targets for antifungal azole derivatives: hypothesis on the mode of action. , 1985, Current topics in medical mycology.

[425] R. A. van der Kammen,et al. Differential expression of the human insulin-like growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated protein. , 1988, Biochimica et biophysica acta.

[426] G. Kreibich,et al. Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[427] M. Ingelman-Sundberg,et al. Mechanism of rate control of the NADPH-dependent reduction of cytochrome P-450 by lipids in reconstituted phospholipid vesicles. , 1984, European journal of biochemistry.

[428] J. Idle,et al. Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes. , 1991, Pharmacogenetics.

[429] M. Atchison,et al. Gene conversion in a cytochrome P-450 gene family. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[430] T. Kimura,et al. Active complex between adrenodoxin reductase and adrenodoxin in the cytochrome P-450scc reduction reaction. , 1989, Journal of biochemistry.

[431] E. Mimnaugh,et al. Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species. , 1975, Drug metabolism and disposition: the biological fate of chemicals.

[432] M. Gustafsson,et al. Conversion of 5β-cholestane-3α,7α,12α,26-tetrol into 3α,7α,12α-trihydroxy-5β-cholestanoic acid by rabbit liver mitochondria , 1988 .

[433] Schmucker Dl,et al. Dietary restriction postpones the age-dependent compromise of male rat liver microsomal monooxygenases. , 1989 .

[434] J. Crivello,et al. Characterization of monoclonal antibodies specific to bovine renal vitamin D hydroxylases. , 1988, Endocrinology.

[435] A. Steward,et al. Changes in the concentration of seven forms of cytochrome P-450 in primary cultures of adult rat hepatocytes. , 1985, Molecular pharmacology.

[436] R. Kumar,et al. Elevated 1,25-dihydroxyvitamin D plasma levels in normal human pregnancy and lactation. , 1979, The Journal of clinical investigation.

[437] J. Dalphin,et al. Lack of a relationship between the polymorphism of debrisoquine oxidation and lung cancer. , 1991, British journal of clinical pharmacology.

[438] T. Meehan,et al. Hydroxylation of geraniol and nerol by a monooxygenase from Vinca rosea. , 1973, Biochemical and biophysical research communications.

[439] M. E. Hahn,et al. Immunohistochemical localization of cytochrome P-450IA1 induced by 3,3',4,4'-tetrachlorobiphenyl and by 2,3,7,8-tetrachlorodibenzoafuran in liver and extrahepatic tissues of the teleost Stenotomus chrysops (scup). , 1991, Drug metabolism and disposition: the biological fate of chemicals.

[440] F. Gonzalez,et al. A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6. , 1991, Carcinogenesis.

[441] N. Javitt,et al. 26-Hydroxycholesterol: synthesis, metabolism, and biologic activities. , 1990, Journal of lipid research.

[442] F. Gonzalez,et al. Transcriptional control of the rat hepatic CYP2E1 gene , 1990, Molecular and cellular biology.

[443] J. Visvader,et al. Differential transcription of exon 1 of the human c-fms gene in placental trophoblasts and monocytes , 1989, Molecular and cellular biology.

[444] M. Marletta,et al. Carcinogen-binding proteins. High-affinity binding sites for benzo[a]pyrene in mouse liver distinct from the Ah receptor. , 1984, Molecular pharmacology.

[445] G. Dobretsov,et al. The influence of cholesterol incorporation and removal on lipid-bilayer viscosity and electron transfer in rat-liver microsomes. , 1983, European journal of biochemistry.

[446] H. DeLuca. Recent advances in the metabolism of vitamin D. , 1981, Annual review of physiology.

[447] T. Aoyama,et al. Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s. , 1991, Archives of biochemistry and biophysics.

[448] N. Ikekawa,et al. Substrate specificity of adrenocortical cytochrome P-450scc--I. Effect of structural modification of cholesterol side-chain on pregnenolone production. , 1980, Journal of steroid biochemistry.

[449] Toru Shimizu,et al. Expression of cytochrome P‐450d by Saccharomyces cerevisiae , 1986, FEBS letters.

[450] A. Dahl,et al. Inhibition of rabbit nasal and hepatic cytochrome P-450-dependent hexamethylphosphoramide (HMPA) N-demethylase by methylenedioxyphenyl compounds. , 1985, Biochemical pharmacology.

[451] F. Snyder,et al. Phospholipid metabolism in rat liver endoplasmic reticulum. Structural analyses, turnover studies and enzymic activities. , 1973, Biochimica et biophysica acta.

[452] H. Murakami,et al. Expression of bovine cytochrome P450c17 cDNA in Saccharomyces cerevisiae. , 1989, DNA.

[453] James M. Roberts,et al. Altering genotype and phenotype by DNA-mediated gene transfer. , 1980, Science.

[454] J. Idle,et al. POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN , 1977, The Lancet.

[455] G. Sewell,et al. The screening of some microorganisms for their ability to N-dealkylate drug molecules , 1984, Applied Microbiology and Biotechnology.

[456] Miriam Khen,et al. Odorant signal termination by olfactory UDP glucuronosyl transferase , 1991, Nature.

[457] Y. Sonoda,et al. Deformylation of 32-oxo-24,25-dihydrolanosterol by the purified cytochrome P-45014DM (lanosterol 14 alpha-demethylase) from yeast evidence confirming the intermediate step of lanosterol 14 alpha-demethylation. , 1989, The Journal of biological chemistry.

[458] N. Darby,et al. Ethanol induces an aniline hydroxylase in chick embryo liver without inducing cytochrome P-450 , 1984 .

[459] D. Blake,et al. Inhibition of hepatic drug metabolism by cyclic 3',5'-adenosine monophosphate. , 1972, Research communications in chemical pathology and pharmacology.

[460] J. Whitlock,et al. Protein-DNA interactions at recognition sites for the dioxin-Ah receptor complex. , 1989, The Journal of biological chemistry.

[461] L. Narhi,et al. Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium. , 1986, The Journal of biological chemistry.

[462] S. Paul,et al. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. , 1986, Science.

[463] L. Geren,et al. Fluorescein isothiocyanate specifically modifies lysine 338 of cytochrome P-450scc and inhibits adrenodoxin binding. , 1989, The Journal of biological chemistry.

[464] R. Horst,et al. Formation of 19-nor-10-keto-25-hydroxyvitamin D3 in cultured mammalian cells. , 1984, Biochemical and biophysical research communications.

[465] F. Murad,et al. Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[466] E. A. Wright,et al. The importance of implantation site in cerebral carcinogenesis in rats. , 1969, Cancer research.

[467] P. Thomas,et al. Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes. , 1983, The Journal of biological chemistry.

[468] A. Y. Lu,et al. Glutathione S-transferases: gene structure, regulation, and biological function. , 1989, Annual review of biochemistry.

[469] J. Gustafsson,et al. Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16 alpha-hydroxylase cytochrome P-450 apoprotein in the rat. , 1985, The Journal of biological chemistry.

[470] J. Lambeth. Chapter 2. Enzymology of Mitochondrial Side-Chain Cleavage by Cytochrome P-450scc , 1990, Molecular mechanisms of adrenal steroidogenesis and aspects of regulation and application.

[471] C. S. Yang,et al. High-affinity nitrosamine dealkylase system in rat liver microsomes and its induction by fasting. , 1983, Cancer research.

[472] T. Shimada,et al. Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[473] D. Russell,et al. Structure of the rat gene encoding cholesterol 7α-hydroxylase , 1990 .

[474] L. Wattenberg,et al. HISTOCHEMICAL DEMONSTRATION OF REDUCED PYRIDINE NUCLEOTIDE DEPENDENT POLYCYCLIC HYDROCARBON METABOLIZING SYSTEMS , 1962 .

[475] R. Tukey,et al. Characterization of multiple human cytochrome P-450 1 cDNAs. The chromosomal localization of the gene and evidence for alternate RNA splicing. , 1987, The Journal of biological chemistry.

[476] M. Trower,et al. Purification and characterization of a soybean flour-induced cytochrome P-450 from Streptomyces griseus , 1989, Journal of bacteriology.

[477] J. Lech,et al. Induction of cytochrome P-450 mRNA in rainbow trout: in vitro translation and immunodetection. , 1988, Toxicology and applied pharmacology.

[478] L. Ignarro. Biosynthesis and metabolism of endothelium-derived nitric oxide. , 1990, Annual review of pharmacology and toxicology.

[479] M. Miyazaki,et al. Long-term survival of functional hepatocytes from adult rat in the presence of phenobarbital in primary culture. , 1985, Experimental cell research.

[480] J. Schenkman,et al. Age and sex differences in constitutive forms of cytochrome P-450 of rat liver microsomes. , 1986, Advances in experimental medicine and biology.

[481] H. Taniguchi,et al. Posttranslational Modification by Phosphorylation: Control of Cytochrome P450 and Associated Enzymes , 1991 .

[482] P. Iversen,et al. Gene structure and nucleotide sequence for rat cytochrome P-450c. , 1985, Archives of biochemistry and biophysics.

[483] K. Krauter,et al. Dexamethasone-mediated regulation of 3-methylcholanthrene-induced cytochrome P-450d mRNA accumulation in primary rat hepatocyte cultures. , 1990, The Journal of biological chemistry.

[484] C. Frayssinet,et al. Metabolism of benzo[a]pyrene by brain microsomes of fetal and adult rats and mice. Induction by 5,6 benzoflavone, comparison with liver and lung microsomal activities. , 1981, Carcinogenesis.

[485] M. J. Coon,et al. Oxygen activation by cytochrome P-450. , 1980, Annual review of biochemistry.

[486] C. Harris,et al. Metabolism of 1,2-dimethylhydrazine by cultured human colon. , 1980, Carcinogenesis.

[487] F. T. Corbin,et al. Metabolism of Metolachlor by a Microsomal Fraction Isolated from Grain Sorghum ( Sorghum bicolor) Shoots , 1990, Zeitschrift fur Naturforschung. C, Journal of biosciences.

[488] L. Sokoloff,et al. Effects of 3-Methylcholanthrene and Phenobarbital on Amino Acid Incorporation into Protein , 1961, Science.

[489] T. Wolff,et al. Monooxygenase and glucuronyltransferase activities in short term cultures of isolated rat hepatocytes , 1979, FEBS letters.

[490] M. J. Coon,et al. Cytochrome P-450 isozymes 2 and 5 in rabbit lung and liver. Comparisons of structure and inducibility. , 1987, Drug metabolism and disposition: the biological fate of chemicals.

[491] B. Moorthy,et al. Reciprocal post-translational regulation of renal 1 alpha- and 24-hydroxylases of 25-hydroxyvitamin D3 by phosphorylation of ferredoxin. mRNA-directed cell-free synthesis and immunoisolation of ferredoxin. , 1990, The Biochemical journal.

[492] C. Jefcoate,et al. Immunological identification and effects of 3-methylcholanthrene and phenobarbital on rat pulmonary cytochrome P-450. , 1987, Cancer research.

[493] O. Käppeli,et al. Controlled expression of heterologous cytochrome P450e cDNA in Saccharomyces cerevisiae. I. Construction and expression of a complete rat cytochrome P450e cDNA , 1989 .

[494] C. Nathan,et al. L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen. , 1990, The Journal of biological chemistry.

[495] S. Imaoka,et al. Simultaneous purification of multiple forms of rat liver microsomal cytochrome P-450 by high-performance liquid chromatography. , 1985, Biochimica et biophysica acta.

[496] M. Leßmann,et al. Specific accumulation of 17 alpha-hydroxyprogesterone in microsomal membranes during the process of cytochrome P-450(C-17)-catalysed androgen biosynthesis. A dynamic study of intermediate formation and turnover. , 1988, The Biochemical journal.

[497] Y. Imai,et al. A gel-electrophoretically homogeneous preparation of cytochrome P-450 from liver microsomes of phenobarbital-pretreated rabbits. , 1974, Biochemical and biophysical research communications.

[498] A. Lee. Interactions of lipids and proteins: Some general principles , 1987, Journal of bioenergetics and biomembranes.

[499] I. C. Gunsalus,et al. Protein components of a cytochrome P-450 linalool 8-methyl hydroxylase. , 1990, The Journal of biological chemistry.

[500] J. Rosazza,et al. Novel Biotransformations of 7-Ethoxycoumarin by Streptomyces griseus , 1983, Applied and environmental microbiology.

[501] G. Padmanaban,et al. Studies on the synthesis of cytochrome P-450 and cytochrome P-448 in rat liver. , 1980, The Journal of biological chemistry.

[502] M. J. Coon,et al. The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. , 1993, DNA and cell biology.

[503] M. J. Coon,et al. Alcohol-inducible cytochrome P-450IIE1 lacking the hydrophobic NH2-terminal segment retains catalytic activity and is membrane-bound when expressed in Escherichia coli. , 1991, The Journal of biological chemistry.

[504] K. Suzuki,et al. Acute decrease by human chorionic gonadotropin of the activity of preovulatory ovarian 17 alpha-hydroxylase and C-17-C-20 lyase is due to decrease of microsomal cytochrome P-450 through de novo synthesis of ribonucleic acid and protein. , 1983, Endocrinology.

[505] J. Gustafsson,et al. cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[506] M. Brodie,et al. Xenobiotic metabolism in the human lung. , 1980, Life sciences.

[507] L. C. Waters,et al. Regulation of insecticide resistance-related cytochrome P-450 expression in Drosophila melanogaster , 1988 .

[508] S. Imaoka,et al. Induction of renal cytochrome P-450 in hepatic microsomes of diabetic rats. , 1988, Biochemical and biophysical research communications.

[509] M. Marletta,et al. Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[510] J R Gillette,et al. Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice. , 1990, Drug metabolism and disposition: the biological fate of chemicals.

[511] M. Bissell,et al. Fructose utilization and altered cytochrome P-450 in cultured hepatocytes from adult rats. , 1980, Biochimica et biophysica acta.

[512] Y. Fujii‐Kuriyama,et al. Site-directed mutageneses of rat liver cytochrome P-450d: axial ligand and heme incorporation. , 1988, Biochemistry.

[513] P. Tempst,et al. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[514] V. Coghlan,et al. Electrostatic interactions stabilizing ferredoxin electron transfer complexes. Disruption by "conservative" mutations. , 1992, The Journal of biological chemistry.

[515] J. Higgins,et al. Phospholipid asymmetry in rough- and smooth-endoplasmic-reticulum membranes of untreated and phenobarbital-treated rat liver. , 1980, The Biochemical journal.

[516] J. Goldstein,et al. Hormonal regulation of male-specific rat hepatic cytochrome P-450g (P-450IIC13) by androgens and the pituitary. , 1989, The Journal of biological chemistry.

[517] M. Pesonen,et al. Characterization and induction of xenobiotic metabolizing enzyme activities in a primary culture of rainbow trout hepatocytes. , 1991, Xenobiotica; the fate of foreign compounds in biological systems.

[518] J. Gustafsson,et al. Growth hormone regulates expression of rat liver cytochrome P-450 15 beta at a pretranslational level. , 1987, Biochemical and biophysical research communications.

[519] D W Nebert,et al. The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects. , 1989, Critical reviews in toxicology.

[520] J. Gustafsson,et al. Preparation and characterization of monoclonal antibodies recognizing unique epitopes on sexually differentiated rat liver cytochrome P-450 isozymes. , 1987, Biochemistry.

[521] B. Halloran,et al. Dietary phosphorus and 1,25-dihydroxyvitamin D metabolism: influence of insulin-like growth factor I. , 1988, Endocrinology.

[522] H. Danielsson,et al. Evidence for a specific cytochrome P-450 with short half-life catalyzing 7 alpha-hydroxylation of cholesterol. , 1981, Biochemical and biophysical research communications.

[523] Y. Fujii‐Kuriyama,et al. Regulatory DNA elements localized remotely upstream from the drug-metabolizing cytochrome P-450c gene. , 1986, Nucleic acids research.

[524] H. Henry,et al. Interactions between intracellular signals involved in the regulation of 25-hydroxyvitamin D3 metabolism. , 1989, Endocrinology.

[525] R. Kato,et al. Suppression of levels of phenobarbital-inducible rat liver cytochrome P-450 by pituitary hormone. , 1987, The Journal of biological chemistry.

[526] W. Seghezzi,et al. Characterization of a second alkane-inducible cytochrome P450-encoding gene, CYP52A2, from Candida tropicalis. , 1991, Gene.

[527] J. Trudell,et al. Phospholipid transfer between vesicles. Dependence on presence of cytochrome P-450 and phosphatidylcholine-phosphatidylethanolamine ratio. , 1982, Biochimica et biophysica acta.

[528] L. Azároff,et al. Phenobarbital induction of cytochrome P-450 gene expression. , 1992, The Biochemical journal.

[529] Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues , 1986 .

[530] H. DeLuca,et al. Isolation of chick renal mitochondrial ferredoxin active in the 25-hydroxyvitamin D3-1alpha-hydroxylase system. , 1976, The Journal of biological chemistry.

[531] R. Gupta,et al. Purification and characterization of cytochrome P-450 isozymes from phenobarbital-induced adult hen liver. , 1990, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

[532] H. Pitot,et al. Dependence of the induction of cytochrome P-450 by phenobarbital in primary cultures of adult rat hepatocytes on the composition of the culture medium. , 1989, Biochemical pharmacology.

[533] D W Nebert,et al. P450 genes: structure, evolution, and regulation. , 1987, Annual review of biochemistry.

[534] D. Waxman,et al. Pituitary regulation of the male-specific steroid 6 beta-hydroxylase P-450 2a (gene product IIIA2) in adult rat liver. Suppressive influence of growth hormone and thyroxine acting at a pretranslational leve;. , 1990, Molecular endocrinology.

[535] K. Yanagibashi,et al. The synthesis of aldosterone by the adrenal cortex. Two zones (fasciculata and glomerulosa) possess one enzyme for 11 beta-, 18-hydroxylation, and aldehyde synthesis. , 1986, The Journal of biological chemistry.

[536] A. Fulco. P450BM-3 and other inducible bacterial P450 cytochromes: biochemistry and regulation. , 1991, Annual review of pharmacology and toxicology.

[537] L. Poellinger,et al. Role of the ligand in intracellular receptor function: receptor affinity determines activation in vitro of the latent dioxin receptor to a DNA-binding form , 1991, Molecular and cellular biology.

[538] O. Gotoh,et al. Structural analysis of the gene encoding rat cholesterol alpha-hydroxylase, the key enzyme for bile acid biosynthesis. , 1991, The Journal of biological chemistry.

[539] D. Jerina,et al. Chemical modification and inactivation of rat liver microsomal cytochrome P-450c by 2-bromo-4'-nitroacetophenone. , 1986, The Journal of biological chemistry.

[540] A. Paine,et al. Immunochemical quantification of cytochrome P450IA and IIB subfamilies in the livers of metyrapone-treated rats. Relevance to the ability of metyrapone to prevent the loss of cytochrome P-450 in rat hepatocyte culture. , 1990, The Biochemical journal.

[541] J. Deybach,et al. [Anesthesia and hepatic porphyria]. , 1989, Annales francaises d'anesthesie et de reanimation.

[542] J. Smith,et al. The involvement of cytochrome P-450 monooxygenase system in aflatoxin biosynthesis by Aspergillus flavus , 2022 .

[543] J. Lambeth,et al. Cytochrome P-450scc-substrate interactions. Studies of binding and catalytic activity using hydroxycholesterols. , 1982, The Journal of biological chemistry.

[544] D. Jerina,et al. Mechanism of inactivation of rat liver microsomal cytochrome P-450c by 2-bromo-4'-nitroacetophenone. , 1986, The Journal of biological chemistry.

[545] A. Rifkind,et al. Kinetic evidence for heterogeneous responsiveness of mixed function oxidase isozymes to inhibition and induction by allylisopropylacetamide in chick embryo liver. , 1982, The Journal of biological chemistry.

[546] M. Zenk,et al. Elicitor induction and characterization of microsomal protopine-6-hydroxylase, the central enzyme in benzophenanthridine alkaloid biosynthesis , 1990 .

[547] J. Behlke,et al. Kinetics of elementary steps in the cytochrome P-450 reaction sequence. III. NADPH reduction of cytochrome P-450LM at different integrational levels. , 1979, Acta biologica et medica Germanica.

[548] H. Suzuki,et al. Purification and properties of cytochrome P-450 (SCC) from pig testis mitochondria. , 1991, Biochemical and biophysical research communications.

[549] M. Waterman,et al. Regulation of steroid hydroxylase gene expression. , 1988, Progress in clinical and biological research.

[550] S. Sligar,et al. The roles of active site hydrogen bonding in cytochrome P-450cam as revealed by site-directed mutagenesis. , 1988, The Journal of biological chemistry.

[551] R. Adamson. Drug metabolism in marine vertebrates. , 1967, Federation proceedings.

[552] M. Ikeda-Saito,et al. Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical. , 1992, The Journal of biological chemistry.

[553] R. Farese. An update on the role of phospholipid metabolism in the action of steroidogenic agents. , 1987, Journal of steroid biochemistry.

[554] P. Watkins,et al. Identification of a polymorphically expressed member of the human cytochrome P-450III family. , 1989, Molecular pharmacology.

[555] T. Omura,et al. Import and processing of the precursor of cytochrome P-450(SCC) by bovine adrenal cortex mitochondria. , 1985, Journal of biochemistry.

[556] S. Yamamoto,et al. Isolation of cytochrome P-450 highly active in prostaglandin omega-hydroxylation from lung microsomes of rabbits treated with progesterone. , 1984, Journal of biochemistry.

[557] J. Steim,et al. Phase transitions in mammalian membranes. , 1972, Biochimica et biophysica acta.

[558] D. Chapman. Phase transitions and fluidity characteristics of lipids and cell membranes , 1975, Quarterly Reviews of Biophysics.

[559] F. Nervi,et al. Bile acid pool changes and regulation of cholate synthesis in experimental diabetes. , 1978, Biochimica et biophysica acta.

[560] D. Hammond,et al. Colonic Microsomal Enzymes and Their Role in Colorectal Carcinogenesis , 1989 .

[561] P. Beaune,et al. Expression of human liver cytochrome P450 IIIA4 in yeast. A functional model for the hepatic enzyme. , 1990, European journal of biochemistry.

[562] M. Goldberg,et al. Molecular analysis of a cytochrome P450 gene of family 4 on the Drosophila X chromosome. , 1992, DNA and cell biology.

[563] F. Gonzalez,et al. Novel exogenous heme-dependent expression of mammalian cytochrome P450 using baculovirus. , 1989, Archives of biochemistry and biophysics.

[564] S. Sligar,et al. The cytochrome P-450cam binding surface as defined by site-directed mutagenesis and electrostatic modeling. , 1990, Biochemistry.

[565] J. Goldstein,et al. Mechanism of action and structure-activity relationships for the chlorinated dibenzo- p- dioxins and related compounds , 1989 .

[566] G. S. Boyd,et al. The cholesterol side-chain cleavage system of bovine adrenal cortex. , 1967, European journal of biochemistry.

[567] A. Rifkind,et al. p-Chloro-N-methylaniline demethylase activity in liver and extrahepatic tissues of the human fetus and in chick embryo liver. , 1981, The Journal of pharmacology and experimental therapeutics.

[568] P. Geary. Molecular Mechanisms of Oxygen Activation , 1975 .

[569] D. Hsieh,et al. Maintenance of cytochrome P-450 and metabolism of aflatoxin B1 in primary hepatocyte cultures. , 1977, Biochemical and biophysical research communications.

[570] R. Steger,et al. Decreased pulsatile release of growth hormone in old male rats. , 1980, Endocrinology.

[571] R. Edwards,et al. Orientation of cytochromes P450 in the endoplasmic reticulum. , 1991, Biochemistry.

[572] W. Thilly,et al. Assay for gene mutation in a human lymphoblast line, AHH-1, competent for xenobiotic metabolism. , 1984, Mutation research.

[573] J. Scott,et al. Immunological detection of cytochrome P450 from insecticide resistant and susceptible house flies () , 1990 .

[574] S. Usanov,et al. Chemical modification of adrenocortical cytochrome P-450scc with tetranitromethane. , 1984, Biochimica et biophysica acta.

[575] Y. Ohyama,et al. Purification and characterization of vitamin D 25-hydroxylase from rat liver mitochondria. , 1988, The Journal of biological chemistry.

[576] T. Iyanagi,et al. Redox properties of the reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 and reduced nicotinamide adenine dinucleotide-cytochrome b5 reductases. , 1974, Biochemistry.

[577] S. Kawato,et al. Rotation and protein-protein interactions of cytochrome P-450 in the inner membrane of adrenocortical mitochondria. , 1988, Journal of biochemistry.

[578] C. Lieber,et al. Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2. , 1989, Archives of biochemistry and biophysics.

[579] J. Gustafsson,et al. Hypothalamo-Pituitary Regulation of Cytochrome P-45015β Apoprotein Levels in Rat Liver , 1985 .

[580] D. Waxman,et al. Microheterogeneity of a male-specific rat hepatic cytochrome P-450: existence of three allozymic forms. , 1985, Archives of biochemistry and biophysics.

[581] J. Miners,et al. Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9. , 1991, Biochemical and biophysical research communications.

[582] F. Oesch,et al. Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins. , 1986, The Biochemical journal.

[583] J. Lambeth,et al. GTP stimulates pregnenolone generation in isolated rat adrenal mitochondria. , 1989, The Journal of biological chemistry.

[584] J. Gustafsson,et al. Sexual differentiation of cytochrome P-450 in rat liver. Evidence for a constitutive isozyme as the male-specific 16 alpha-hydroxylase. , 1985, Molecular pharmacology.

[585] R. Kraft,et al. Chemical modification of cytochrome P-450 LM4. Identification of functionally linked tyrosine residues. , 1987, Biochimica et biophysica acta.

[586] D. Stone,et al. Studies on ACTH action in perfused bovine adrenals: aspects of progesterone as an intermediary in corticosteroidogenesis. , 1955, Archives of biochemistry and biophysics.

[587] A. Brash,et al. Purification of an allene oxide synthase and identification of the enzyme as a cytochrome P-450. , 1991, Science.

[588] M. Wagner,et al. Functional Expression of the Alkane-Inducible Monooxygenase System of the Yeast: Candida tropicalis IN Saccharomyces cerevisiae , 1990 .

[589] Y. Fujii‐Kuriyama,et al. Aberrant splicing and missense mutations cause steroid 21-hydroxylase [P-450(C21)] deficiency in humans: possible gene conversion products. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[590] C. Mendelson,et al. Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[591] G. S. Boyd,et al. Studies on Rat‐Liver Microsomal Cholesterol 7α‐Hydroxylase , 1973 .

[592] L. Narhi,et al. Identification and characterization of two functional domains in cytochrome P-450BM-3, a catalytically self-sufficient monooxygenase induced by barbiturates in Bacillus megaterium. , 1987, The Journal of biological chemistry.

[593] T. Kamataki,et al. Sex difference of cytochrome P-450 in the rat: purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats. , 1983, Archives of biochemistry and biophysics.

[594] F J Wiebel,et al. H4IIEC3 rat hepatoma cells activate N-nitrosodimethylamine but are resistant to the genotoxic products. , 1989, Mutagenesis.

[595] A. Hinnen,et al. Constitutive and inducible expression of human cytochrome P450IA1 in yeast Saccharomyces cerevisiae: an alternative enzyme source for in vitro studies. , 1990, Biochemical and biophysical research communications.

[596] C. Wolf,et al. The rabbit pulmonary monooxygenase system: characteristics and activities of two forms of pulmonary cytochrome P-450. , 1978, Chemico-biological interactions.

[597] T. Kamataki,et al. Pituitary regulation of sex-specific forms of cytochrome P-450 in liver microsomes of rats. , 1985, Biochemical and biophysical research communications.

[598] H. Remmer. [The acceleration of evipan oxidation and the demethylation of methylaminopyrine by barbiturates]. , 1959, Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie.

[599] S. Sligar,et al. Nucleotide sequence of the Pseudomonas putida cytochrome P-450cam gene and its expression in Escherichia coli. , 1986, The Journal of biological chemistry.

[600] H. DeLuca,et al. 25-Hydroxyvitamin D3-1-hydroxylase. Inhibition in vitro by rat and pig tissues. , 1974, Biochemistry.

[601] T. Wise,et al. Nucleotide sequence of cytochrome P-450 cholesterol side-chain cleavage cDNA isolated from porcine testis. , 1989, Nucleic acids research.

[602] S. Shenolikar. Protein phosphorylation: hormones, drugs, and bioregulation , 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[603] P. Strittmatter,et al. Modification and identification of cytochrome b5 carboxyl groups involved in protein-protein interaction with cytochrome b5 reductase. , 1979, The Journal of biological chemistry.

[604] T. Ogishima,et al. Isolation of two distinct cytochromes P-45011 beta with aldosterone synthase activity from bovine adrenocortical mitochondria. , 1989, Journal of biochemistry.

[605] J. Stegeman,et al. Cytochrome P-450 isozymes and monooxygenase activity in aquatic animals. , 1987, Environmental health perspectives.

[606] J. Sutherland,et al. Demethylation of Veratrole by Cytochrome P-450 in Streptomyces setonii , 1986, Applied and environmental microbiology.

[607] G. E. Pratt,et al. The absolute configuration of precocene I dihydrodiols produced by metabolism of precocene I by corpora allata of Locusta migratoria, in vitro. , 1983, Life sciences.

[608] H. Murakami,et al. Genetically engineered modification of P450 monooxygenases: functional analysis of the amino-terminal hydrophobic region and hinge region of the P450/reductase fused enzyme. , 1988, DNA.

[609] L. Vickery. Active site-directed inhibitors of steroid hydroxylase cytochromes P450. , 1991, Methods in enzymology.

[610] T. Masuko,et al. Changes in the Quantity and Activity of Cytochrome P‐450 Isozymes in Primary Cultured Rat Hepatocytes , 1989, Japanese journal of cancer research : Gann.

[611] W. K. Wilson,et al. Inhibitors of sterol synthesis. Characterization of side chain oxygenated derivatives formed upon incubation of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one with rat liver mitochondria. , 1989, The Journal of biological chemistry.

[612] D. Dutta,et al. Microsomal benzo(a)pyrene hydroxylase in Aspergillus ochraceus TS: assay and characterization of the enzyme system. , 1983, Biochemical and biophysical research communications.

[613] M. J. Coon,et al. Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes. , 1985, Cancer research.

[614] R. Prince,et al. Rapid nongenomic inhibition of renal 25-hydroxyvitamin D3 1-hydroxylase by 1,25-dihydroxyvitamin D3. , 1990, The American journal of physiology.

[615] N. Thierry,et al. Hydroxylation, sulfation, and conjugation of bile acids in rat hepatoma and hepatocyte cultures under the influence of glucocorticoids. , 1980, The Journal of biological chemistry.

[616] P. Rangarajan,et al. Regulation of cytochrome P-450b/e gene expression by a heme- and phenobarbitone-modulated transcription factor. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[617] M. J. Coon,et al. Incorporation of the cytochrome P-450 monooxygenase system into large unilamellar liposomes using octylglucoside, especially for measurements of protein diffusion in membranes. , 1984, Biochemical and biophysical research communications.

[618] J. Stegeman. Cytochrome P450 forms in fish: catalytic, immunological and sequence similarities. , 1989, Xenobiotica; the fate of foreign compounds in biological systems.

[619] L. Corcos,et al. Phenobarbital, dexamethasone and benzanthracene induce several cytochrome P450 mRNAs in rat hepatoma cells , 1988, FEBS letters.

[620] T. Kawamoto,et al. Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism. , 1990, Biochemical and biophysical research communications.

[621] D. Lancet,et al. Identification and biochemical analysis of novel olfactory-specific cytochrome P-450IIA and UDP-glucuronosyl transferase. , 1990, Biochemistry.

[622] A. Guillouzo,et al. Maintenance of cytochrome P-450 in cultured adult human hepatocytes. , 1985, Biochemical pharmacology.

[623] T. Ogihara,et al. Molecular cloning and expression of cDNAs encoding rat aldosterone synthase: Variants of cytochrome P-45011β , 1990 .

[624] M. S. Kirkman,et al. Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme. , 1990, The Journal of biological chemistry.

[625] D. Nelson,et al. Secondary structure prediction of 52 membrane-bound cytochromes P450 shows a strong structural similarity to P450cam. , 1989, Biochemistry.

[626] T. Shimada,et al. Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction. , 1986, The Journal of biological chemistry.

[627] P. Chambon,et al. The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer , 1988, Cell.

[628] H. Ohkawa,et al. Expression of rat liver cytochrome P-450MC cDNA in Saccharomyces cerevisiae. , 1985, DNA.

[629] L. E. Rikans,et al. Effect of methyltestosterone administration on microsomal drug metabolism in aging rats , 1984, Mechanisms of Ageing and Development.

[630] E. Arinç,et al. Preparation and properties of partially purified pulmonary cytochrome P-450 from rabbits. , 1976, The Journal of biological chemistry.

[631] H. Jörnvall,et al. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. , 1989, The Journal of biological chemistry.

[632] H. Boström. Characterization of 6 alpha-hydroxylation of taurochenodeoxycholic acid in pig liver. , 1986, Journal of lipid research.

[633] N. Serizawa,et al. Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B). , 1983, The Journal of antibiotics.

[634] C A Prompt,et al. [Cyclosporin A: drug interactions]. , 1991, AMB : revista da Associacao Medica Brasileira.

[635] T. Sutter,et al. Primary structure of the P450 lanosterol demethylase gene from Saccharomyces cerevisiae. , 1987, DNA.

[636] A. Paine,et al. Nutrient imbalance causes the loss of cytochrome P-450 in liver cell culture: formulation of culture media which maintain cytochrome P-450 at in vivo concentrations. , 1980, Biochemical pharmacology.

[637] C. Larroque,et al. Interaction of a spin-labelled cholesterol derivative with the cytochrome P-450scc active site. , 1988, European journal of biochemistry.

[638] I. Björkhem,et al. Cerebrotendinous xanthomatosis: a defect in mitochondrial 26-hydroxylation required for normal biosynthesis of cholic acid. , 1980, The Journal of clinical investigation.

[639] G. Kochs,et al. Phytoalexin synthesis in soybean: purification and reconstitution of cytochrome P450 3,9-dihydroxypterocarpan 6a-hydroxylase and separation from cytochrome P450 cinnamate 4-hydroxylase. , 1989, Archives of biochemistry and biophysics.

[640] I. C. Gunsalus,et al. A soluble cytochrome P-450 functional in methylene hydroxylation. , 1968, The Journal of biological chemistry.

[641] T. Mohandas,et al. ASSIGNMENT OF THE GENE FOR ADRENAL P450cl7 (STEROID 17α-HYDR0XYLASE⁄17,20 LYASE) TO HUMAN CHROMOSOME 10. , 1986 .

[642] G. S. Boyd. Biochemistry, Biophysics and Regulation of Cytochrome P-450 , 1981 .

[643] P. Beaune,et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1. , 1991, Chemical research in toxicology.

[644] G. Vlasuk,et al. Phenobarbital induction of rat liver cytochromes P-450b and P-450e. Quantitation of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes. , 1985, The Journal of biological chemistry.

[645] G. Langolf,et al. Behavioural evaluation of workers exposed to mixtures of organic solvents. , 1985, British journal of industrial medicine.

[646] P. R. Montellano. Cytochrome P-450 , 1986, Springer US.

[647] A. van der Eb,et al. A new technique for the assay of infectivity of human adenovirus 5 DNA. , 1973, Virology.

[648] S. Ellard,et al. The use of genetically engineered V79 Chinese hamster cultures expressing rat liver CYP1A1, 1A2 and 2B1 cDNAs in micronucleus assays. , 1991, Mutagenesis.

[649] D. Waxman. Rat hepatic cytochrome P-450 isoenzyme 2c. Identification as a male-specific, developmentally induced steroid 16 alpha-hydroxylase and comparison to a female-specific cytochrome P-450 isoenzyme. , 1984, The Journal of biological chemistry.

[650] P. Hwang,et al. Human prolactin. , 1973, Annual Review of Medicine.

[651] I. Björkhem,et al. Biosynthesis of bile acids in man. Hydroxylation of the C27-steroid side chain. , 1975, The Journal of clinical investigation.

[652] S. Mellon,et al. Zone-specific regulation of two messenger RNAs for P450c11 in the adrenals of pregnant and nonpregnant rats. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[653] K. Higashi,et al. Isolation of immunochemically distinct form of cytochrome P-450 from microsomes of tulip bulbs. , 1983, Biochemical and biophysical research communications.

[654] J. Salaün,et al. A microsomal (cytochrome P-450)-linked lauric-acid-monooxygenase from aged Jerusalem-artichoke-tuber tissues. , 1978, European journal of biochemistry.

[655] D. Fredrickson,et al. The in vitro production of 25- and 26-hydroxycholesterol and their in vivo metabolism. , 1956, Biochimica et biophysica acta.

[656] J. Salaün,et al. Epoxidation of cis and trans Δ9‐unsaturated lauric acids by a cytochrome P‐450‐dependent system from higher plant microsomes , 1989 .

[657] M. Waterman,et al. Transcriptional regulation of the bovine CYP17 (P-450(17)alpha) gene. Identification of two cAMP regulatory regions lacking the consensus cAMP-responsive element (CRE). , 1990, The Journal of biological chemistry.

[658] H. Müller,et al. Molecular cloning and characterization of the primary structure of the alkane hydroxylating cytochrome P-450 from the yeast Candida maltosa. , 1989, Biochemical and biophysical research communications.

[659] T. Kimura,et al. The formation of binary and ternary complexes of cytochrome P-450scc with adrenodoxin and adrenodoxin reductase.adrenodoxin complex. The implication in ACTH function. , 1979, The Journal of biological chemistry.

[660] M. J. Coon,et al. Induction and tissue-specific expression of rabbit cytochrome P450IIE1 and IIE2 genes. , 1989, Molecular pharmacology.

[661] E. Suolinna,et al. Effect of culture age on drug metabolizing enzymes and their induction in primary cultures of rat hepatocytes. , 1986, Biochemical pharmacology.

[662] S. Sligar,et al. Cytochrome P-450cam and Other Bacterial P-450 Enzymes , 1986 .

[663] J. Casazza,et al. Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes. , 1985, The Journal of biological chemistry.

[664] J. Adams,et al. A role for endogenous arachidonate metabolites in the regulated expression of the 25-hydroxyvitamin D-1-hydroxylation reaction in cultured alveolar macrophages from patients with sarcoidosis. , 1990, The Journal of clinical endocrinology and metabolism.

[665] Inhibitory Action , 1906, Botanical Gazette.

[666] S. Imaoka,et al. A sex-specific form of cytochrome P-450 catalyzing propoxycoumarin O-depropylation and its identity with testosterone 6 beta-hydroxylase in untreated rat livers: reconstitution of the activity with microsomal lipids. , 1988, Journal of biochemistry.

[667] G. Padmanaban,et al. Turnover of messenger RNA, apoprotein and haem of cytochrome P-450b + e induced by phenobarbitone in rat liver. , 1985, The Biochemical journal.

[668] A. Ashworth,et al. Isolation and sequence of a human cytochrome P-450 cDNA clone. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[669] D. Waxman,et al. Cytochrome P-450 cholesterol 7 alpha-hydroxylase: inhibition of enzyme deactivation by structurally diverse calmodulin antagonists and phosphatase inhibitors. , 1987, Archives of biochemistry and biophysics.

[670] Masahiko Watanabe,et al. Purification of Cytochrome P-450alk from n-Alkane-grown Cells of Candida maltosa, and Cloning and Nucleotide Sequencing of the Encoding Gene , 1989 .

[671] W. Orme-Johnson,et al. Steroid binding properties of beef adrenal cortical cytochrome P-450 which catalyzes the conversion of cholesterol into pregnenolone. , 1979, The Journal of biological chemistry.

[672] F. Guengerich,et al. Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism. , 1985, The Journal of biological chemistry.

[673] P. Thomas,et al. Rat hepatic cytochrome P-450 isozyme specificity for the metabolism of the steroid sulfate, 5α-androstane-3α,17β-diol-3,17-disulfate , 1984 .

[674] J. Mason,et al. Immunohistochemical analysis of cytochrome P-450 17α-hydroxylase in pig adrenal cortex, testis and ovary , 1989, Molecular and Cellular Endocrinology.

[675] M. Correia,et al. Purification and characterization of a mouse liver cytochrome P-450 induced by cannabidiol. , 1989, Molecular pharmacology.

[676] M. Sternberg,et al. A predicted three-dimensional structure of human cytochrome P450: implications for substrate specificity. , 1991, Protein engineering.

[677] C. Kozak,et al. Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene. , 1989, Biochemistry.

[678] C. Larroque,et al. The subzero temperature stabilized oxyferro complex of purified cytochrome P450SCC , 1980, FEBS letters.

[679] H. DeLuca,et al. Mitochondrial Cytochrome P450 A COMPONENT OF CHICK KIDNEY 25-HYDROXYCHOLECALCIFEROL-1α-HYDROXYLASE , 1974 .

[680] G. Vergères,et al. Chemical modification of rat liver microsomal cytochrome P-450: study of enzymic properties and membrane topology. , 1991, Biochimica et biophysica acta.

[681] U. Muller-eberhard,et al. Differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome P-450: evidence for tissue specificity. , 1980, Molecular pharmacology.

[682] S. Imaoka,et al. ω- and (ω - 1) -hydroxylation of arachidonic acid, lauric acid and prostaglandin A1 by multiple forms of cytochrome P-450 purified from rat hepatic microsomes , 1990 .

[683] C. Hutchinson,et al. Purification and reconstitution of the electron transport components for 6-deoxyerythronolide B hydroxylase, a cytochrome P-450 enzyme of macrolide antibiotic (erythromycin) biosynthesis , 1988, Journal of bacteriology.

[684] B. May,et al. EFFECT OF HAEM ON CYTOCHROME P‐450 SYNTHESIS , 1989, Clinical and experimental pharmacology & physiology.

[685] Y. Hokama,et al. Purification and characterization of two forms of chicken liver cytochrome P-450 induced by 3,4,5,3',4'-pentachlorobiphenyl. , 1988, Journal of biochemistry.

[686] H. Postlind. Separation of the cytochromes P-450 in pig kidney mitochondria catalyzing 1 alpha-, 24- and 26-hydroxylations of 25-hydroxyvitamin D3. , 1990, Biochemical and biophysical research communications.

[687] M. J. Coon,et al. Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: deformylation with olefin formation. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[688] J. Gustafsson,et al. Isolation and catalytic activity of cytochrome P-450 from ventral prostate of control rats. , 1987, The Journal of biological chemistry.

[689] K. Wikvall. Hydroxylations in biosynthesis of bile acids. Isolation of a cytochrome P-450 from rabbit liver mitochondria catalyzing 26-hydroxylation of C27-steroids. , 1984, The Journal of biological chemistry.

[690] V. Rogiers,et al. Effects of dimethylsulphoxide on phase I and II biotransformation in cultured rat hepatocytes. , 1990, Toxicology in vitro : an international journal published in association with BIBRA.

[691] T. Kamataki,et al. Age-related alteration in the activities of drug-metabolizing enzymes and contents of sex-specific forms of cytochrome P-450 in liver microsomes from male and female rats. , 1985, The Journal of pharmacology and experimental therapeutics.

[692] C. Coscia,et al. Subcellular localization of a cytochrome P-450-dependent monogenase in vesicles of the higher plant Catharanthus roseus , 1977, The Journal of cell biology.

[693] D M Bissell,et al. Drug metabolism in adult rat hepatocytes in primary monolayer culture. , 1977, Gastroenterology.

[694] M. Haniu,et al. Heme binding and substrate-protected cysteine residues in P-450cam. , 1983, Biochemical and biophysical research communications.

[695] Madhyastha Km,et al. Microbiological transformations of terpenes. XV. Enzyme systems in the catabolism of p-cymene in PL-strain. , 1968 .

[696] A. Smals,et al. Indirect evidence of chronic Leydig cell desensitization in Klinefelter's syndrome. , 1981, Acta endocrinologica.

[697] D. Waxman,et al. Phenobarbital induction of cytochromes P-450. High-level long-term responsiveness of primary rat hepatocyte cultures to drug induction, and glucocorticoid dependence of the phenobarbital response. , 1990, The Biochemical journal.

[698] D. Johnson,et al. The cytochrome P45017α (17α-hydroxylase/C17,20-lyase) activity of the junctional zone of the rat placenta , 1990 .

[699] L. Wolin,et al. The formation of estrogens by central neuroendocrine tissues. , 1975, Recent progress in hormone research.

[700] R. Kato,et al. Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes. , 1965, The Journal of pharmacology and experimental therapeutics.

[701] O. Käppeli,et al. The distinction of different types of cytochromes P-450 from the yeasts Candida tropicalis and Saccharomyces uvarum. , 1986, Archives of biochemistry and biophysics.

[702] M. Marletta,et al. Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor. , 1989, The Journal of biological chemistry.

[703] H. Rennert,et al. A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries. , 1990, DNA and cell biology.

[704] S. Bloom,et al. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: ontogeny in chick embryo liver. , 1986, Journal of biochemical toxicology.

[705] B. Tamaoki,et al. Fate of molecular oxygen required by endocrine enzymes for the side-chain cleavage of cholesterol. , 1968, Biochimica et biophysica acta.

[706] F. Guengerich,et al. Isolation and purification of cytochrome P-450, and the existence of multiple forms. , 1979, Pharmacology & therapeutics.

[707] C. Lieber,et al. Bile acids in deermice lacking liver alcohol dehydrogenase. , 1985, Biochimica et biophysica acta.

[708] E. Kendall. THE FUNCTION OF THE ADRENAL CORTEX , 1941 .

[709] U. Matern,et al. Biosynthesis of psoralens Psoralen 5‐monooxygenase activity from elicitor‐treated Ammi majus cells , 1988, FEBS letters.

[710] M. Warner. Catalytic activity of partially purified renal 25-hydroxyvitamin D hydroxylases from vitamin D-deficient and vitamin D-replete rats. , 1982, The Journal of biological chemistry.

[711] M. Ingelman-Sundberg,et al. Membrane charge as effector of cytochrome P-450LM2 catalyzed reactions in reconstituted liposomes. , 1981, Biochemistry.

[712] J. Gielen,et al. Rat-liver cholesterol 7alpha-hydroxylase. 3. New results about its circadian rhythm. , 1975, European journal of biochemistry.

[713] O. Mcbride,et al. Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression. , 1988, Biochemistry.

[714] J. S. Mallov. MBK neuropathy among spray painters. , 1976, JAMA.

[715] M. Relling,et al. Xbal 16- plus 9-kilobase DNA restriction fragments identify a mutant allele for debrisoquin hydroxylase: report of a family study. , 1990, Molecular pharmacology.

[716] W. Snodgrass,et al. Phenytoin metabolic activation: role of cytochrome P-450, glutathione, age, and sex in rats and mice. , 1988, Research communications in chemical pathology and pharmacology.

[717] G. Dallner,et al. Transverse asymmetry of phospholipids in subcellular membranes of rat liver. , 1977, Biochimica et biophysica acta.

[718] A. Conney,et al. PUROMYCIN INHIBITION OF ENZYME INDUCTION BY 3-METHYLCHOLANTHRENE AND PHENOBARBITAL. , 1963, The Journal of biological chemistry.

[719] R. Kumar,et al. Do tissues other than the kidney produce 1,25-dihydroxyvitamin D3 in vivo? A reexamination. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[720] N. Elshourbagy,et al. Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents. , 1982, Molecular pharmacology.

[721] M. Marletta,et al. Mechanistic probes of N-hydroxylation of L-arginine by the inducible nitric oxide synthase from murine macrophages. , 1992, Biochemistry.

[722] J. Fishman,et al. 19-Hydroxylation and aromatization of androgens in the developing rat brain. , 1987, Endocrinology.

[723] Y. Fujii‐Kuriyama,et al. Structural analysis and specific expression of microsomal cytochrome P-450(M-1) mRNA in male rat livers. , 1987, The Journal of biological chemistry.

[724] R. Kato,et al. Nucleotide sequence of a human liver cytochrome P-450 related to the rat male specific form. , 1987, Journal of biochemistry.

[725] A. Y. Lu,et al. Reconstituted mammalian mixed-function oxidases: Requirements, specificities and other properties , 1978 .

[726] M. J. Coon,et al. Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols. , 1982, The Journal of biological chemistry.

[727] R. Philpot,et al. The effect of substrate on the expression of activity catalyzed by cytochrome P-450: metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems. , 1986, Archives of biochemistry and biophysics.

[728] Y. Fujii‐Kuriyama,et al. Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver. , 1985, The Journal of biological chemistry.

[729] D. Lancet,et al. Immunolocalization of cytochromes P-450olf1 and P-450olf2 in rat olfactory mucosa. , 1991, European journal of biochemistry.

[730] C. Mendelson,et al. Regulation of estrogen biosynthesis by human adipose cells. , 1989, Endocrine reviews.

[731] G. Padmanaban,et al. Involvement of heme in the transcriptional activation of CYPIIB1/B2 gene by phenobarbitone in rat liver--studies with succinylacetone. , 1991, Archives of biochemistry and biophysics.

[732] H. DeLuca,et al. Determination of vitamin D and its metabolites in plasma from normal and anephric man. , 1979, The Biochemical journal.

[733] S. Mohla,et al. Regulation of renal N-nitrosodimethylamine demethylase activity by androgens, progestin, glucocorticoid, and estrogen in BALB/c mice. , 1989, Cancer research.

[734] J. Finkelstein,et al. METABOLISM OF VITAMIN D. I. PREPARATION OF RADIOACTIVE VITAMIN D AND ITS INTESTINAL ABSORPTION IN THE RAT. , 1964, The Journal of clinical investigation.

[735] T. Kamataki,et al. Partial purification and properties of cytochrome P450 from homogenates of human fetal livers. , 1979, Biochemical pharmacology.

[736] U. Matern,et al. Elicitor-induced biosynthesis of psoralens in Ammi majus L. suspension cultures. Microsomal conversion of demethylsuberosin into (+)marmesin and psoralen. , 1988, European journal of biochemistry.

[737] T. Kawamoto,et al. Isolation of a full-length cDNA encoding mouse aromatase P450. , 1991, Archives of biochemistry and biophysics.

[738] J. Whitlock,et al. Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells. , 1984, The Journal of biological chemistry.

[739] J. Porter,et al. Cloning of DNA complementary to rat liver fatty acid synthetase mRNA. , 1984, European journal of biochemistry.

[740] H. Fleisch,et al. Regulation of the metabolism of 25-hydroxyvitamin D3 in primary cultures of chick kidney cells. , 1979, The Journal of clinical investigation.

[741] G. Kochs,et al. Induction and Characterization of a NADPH-Dependent Flavone Synthase from Cell Cultures of Soybean , 1987 .

[742] M. Noshiro,et al. Cloning and expression of cDNA encoding 25‐hydroxyvitamin D3 24‐hydroxylase , 1991, FEBS letters.

[743] D. Hammond,et al. Ethoxyresorufin O-deethylase activity in intact human cells. , 1992, Toxicology in vitro : an international journal published in association with BIBRA.

[744] M. J. Coon,et al. Immunochemical characterization of multiple forms of cytochrome P-450 in rabbit nasal microsomes and evidence for tissue-specific expression of P-450s NMa and NMb. , 1990, Molecular pharmacology.

[745] P. Guzelian,et al. Effect of cobalt on synthesis of heme and cytochrome P-450 in the liver. Studies of adult rat hepatocytes in primary monolayer culture and in vivo. , 1976, The Journal of biological chemistry.

[746] R. Philpot,et al. Species-dependent expression and induction of homologues of rabbit cytochrome P-450 isozyme 5 in liver and lung. , 1987, Molecular pharmacology.

[747] I. Bekersky,et al. Feedback regulation of bile acid biosynthesis in the rat. , 1969, Journal of lipid research.

[748] T. Poulos,et al. Characterization of recombinant Bacillus megaterium cytochrome P-450 BM-3 and its two functional domains. , 1991, The Journal of biological chemistry.

[749] A. Conney,et al. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. , 1982, Cancer research.

[750] T. Omura,et al. In vitro synthesis of mitochondrial cytochromes P-450(scc) and P-450(11-beta) and microsomal cytochrome P-450(C-21) by both free and bound polysomes isolated from bovine adrenal cortex. , 1980, Biochemical and biophysical research communications.

[751] J. Maher. Primary hepatocyte culture: Is it home away from home? , 1988, Hepatology.

[752] H. Mukhtar,et al. 7-Ethoxycoumarin O-de-ethylase activity in rat brain microsomes. , 1983, Biochemical pharmacology.

[753] J. Lambeth,et al. Stimulation of adrenal mitochondrial cholesterol side-chain cleavage by GTP, steroidogenesis activator polypeptide (SAP), and sterol carrier protein2. GTP and SAP act synergistically. , 1991, The Journal of biological chemistry.

[754] M. J. Coon,et al. Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: similarity to hydrophobic amino-terminal segments of preproteins. , 1977, Biochemical and biophysical research communications.

[755] F. Guengerich,et al. Purification and characterization of the rat liver microsomal cytochrome P-450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism. , 1984, Biochemistry.

[756] S. Snyder,et al. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[757] J. Mathis,et al. Identification of multiple regulatory elements on the human cytochrome P450IA1 gene. , 1988, Carcinogenesis.

[758] D. L. Schmucker. Aging and drug disposition: an update. , 1985, Pharmacological reviews.

[759] B. Cohen,et al. Cerebrotendinous xanthomatosis: reduced serum 26-hydroxycholesterol. , 1982, Journal of lipid research.

[760] P. Siiteri,et al. Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age. , 1974, The Journal of clinical endocrinology and metabolism.

[761] I. Björkhem,et al. ω‐Hydroxylation of Steroid Side‐Chain in Biosynthesis of Bile Acids , 1973 .

[762] O. Käppeli,et al. Metabolic conditions determining the composition and catalytic activity of cytochrome P-450 monooxygenases in Candida tropicalis , 1984, Journal of bacteriology.

[763] T. Kamataki,et al. Effect of growth hormone and ectopic transplantation of pituitary gland on sex-specific forms of cytochrome P-450 and testosterone and drug oxidations in rat liver. , 1986, Journal of biochemistry.

[764] E. Glover,et al. Genetic Expression of Aryl Hydrocarbon Hydroxylase by 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Evidence for a Receptor Mutation in Genetically Non-responsive Mice , 1975 .

[765] K. Einarsson,et al. Bile acid synthesis in humans: regulation of hepatic microsomal cholesterol 7 alpha-hydroxylase activity. , 1989, Gastroenterology.

[766] T. Kamataki,et al. Partial purification and characterization of cytochrome P-450 responsible for the occurrence of sex difference in drug metabolism in the rat. , 1981, Biochemical and biophysical research communications.

[767] F. Gonzalez,et al. The molecular biology of cytochrome P450s. , 1988, Pharmacological reviews.

[768] Clinton Scoltard. The Pathway , 1899 .

[769] S J Singer,et al. The molecular organization of membranes. , 1974, Annual review of biochemistry.

[770] E. Johnson,et al. Isolation and characterization of a constitutive form of rabbit liver microsomal cytochrome P-450. , 1980, The Journal of biological chemistry.

[771] F. Guengerich,et al. Identification and quantitation of a 2.0-kilobase messenger ribonucleic acid coding for 3-methylcholanthrene-induced cytochrome P-450 using cloned cytochrome P-450 complementary deoxyribonucleic acid. , 1982, Biochemistry.

[772] J. Hevel,et al. Unraveling the biological significance of nitric oxide. , 1990, BioFactors.

[773] F. Gonzalez,et al. Developmental regulation of hepatic testosterone hydroxylases: simultaneous activation and repression of constitutively expressed cytochromes P450 in senescent rats. , 1990, Archives of biochemistry and biophysics.

[774] P. Srivastava,et al. Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes. , 1991, Molecular Pharmacology.

[775] Yao-Tseng Chen,et al. Transfection of a human cytochrome P-450 gene into the human lymphoblastoid cell line, AHH-1, and use of the recombinant cell line in gene mutation assays. , 1989, Carcinogenesis.

[776] C. Lieber. Metabolic Effects of Ethanol and Its Interaction with Other Drugs, Hepatotoxic Agents, Vitamins, and Carcinogens: A 1988 Update , 1988, Seminars in liver disease.

[777] J. Felton,et al. Introduction of cytochrome P450IA2 metabolic capability into cell lines genetically matched for DNA repair proficiency/deficiency. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[778] W. Powell. omega-Oxidation of prostaglandins by lung and liver microsomes. Changes in enzyme activity induced by pregnancy, pseudopregnancy, and progesterone treatment. , 1978, The Journal of biological chemistry.

[779] M. Fisher,et al. Possible role for covalent modification in the reversible activation of ecdysone 20-monooxygenase activity , 1989 .

[780] J. Zerwekh,et al. Human placental production of 1 alpha,25-dihydroxyvitamin D3: biochemical characterization and production in normal subjects and patients with pseudohypoparathyroidism. , 1986, The Journal of clinical endocrinology and metabolism.

[781] C. Hansch,et al. Induction of Cytochrome P450 by Barbiturates in Chick Embryo Hepatocytes: A Quantitative Structure-Activity Analysis , 1990 .

[782] H. Glatt,et al. Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[783] C. F. Strittmatter,et al. Oxidative enzyme components of avian liver microsomes. Changes during embryonic development and the effects of phenobarbital administration. , 1969, Biochimica et biophysica acta.

[784] H. Remmer,et al. Drug-Induced Changes in the Liver Endoplasmic Reticulum: Association with Drug-Metabolizing Enzymes , 1963, Science.

[785] N. Harada,et al. Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. , 1984, The Journal of biological chemistry.

[786] D. Müller,et al. The influence of age and of the inducer phenobarbital on the cytochrome P-450 dependent monooxygenation of drugs in rat liver. , 1978, Die Pharmazie.

[787] C. Kozak,et al. Debrisoquine 4-hydroxylase: characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DA rat polymorphism. , 1987, DNA.

[788] Evidence for the formation of 26-hydroxycholesterol by cytochrome P-450 in pig kidney mitochondria. , 1989, Biochemical and biophysical research communications.

[789] C. Nathan,et al. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[790] J. Schenkman,et al. Decrease in the levels of a constitutive cytochrome P-450 (RLM5) in hepatic microsomes of diabetic rats. , 1987, Biochemical and biophysical research communications.

[791] Y. Yoshida,et al. Different substrate specificities of lanosterol 14a-demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24-methylene-24,25-dihydrolanosterol and 24,25-dihydrolanosterol. , 1991, Biochemical and biophysical research communications.

[792] P. Thomas,et al. A regulatory polymorphism for rat hepatic cytochrome P-450g. , 1987, Archives of biochemistry and biophysics.

[793] S. Wrighton,et al. Regulation of cytochrome P-450p by phenobarbital and phenobarbital-like inducers in adult rat hepatocytes in primary monolayer culture and in vivo. , 1986, Biochemistry.

[794] H. Rees,et al. Ecdysone 20-mono-oxygenase in the desert locust, Schistocerca gregaria. , 1984, The Biochemical journal.

[795] O. Gotoh,et al. Structure and drug inducibility of the human cytochrome P-450c gene. , 1986, European journal of biochemistry.

[796] M. J. Coon,et al. Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[797] B. Hollis. 25-Hydroxyvitamin D3-1 alpha-hydroxylase in porcine hepatic tissue: subcellular localization to both mitochondria and microsomes. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[798] T. Ogishima,et al. Molecular cloning of a cDNA encoding aldosterone synthase cytochrome P‐450 in rat adrenal cortex , 1990, FEBS letters.

[799] J. Phillips. Cytochrome P-450: Biochemistry and biophysics , 1990 .

[800] R. Larson,et al. Microsomal flavonoid 3'-monooxygenase from maize seedlings. , 1986, Plant physiology.

[801] C. Hutchinson,et al. Macrolide antibiotic biosynthesis: isolation and properties of two forms of 6-deoxyerythronolide B hydroxylase from Saccharopolyspora erythraea (Streptomyces erythreus). , 1987, Biochemistry.

[802] R. Galinsky,et al. Effect of aging on hepatic biotransformation in female Fischer 344 rats: changes in sulfotransferase activities are consistent with known gender-related changes in pituitary growth hormone secretion in aging animals. , 1990, The Journal of pharmacology and experimental therapeutics.

[803] E. Evans,et al. Purification and properties of cytochrome P-450-dependent 14 alpha-sterol demethylase from Candida albicans. , 1989, The Biochemical journal.

[804] L. Corcos,et al. Establishment of mouse and rat hepatoma cell clones showing stable expression of rabbit cytochrome P450 IA2 , 1989, FEBS letters.

[805] J. Depierre,et al. Enzyme topology of intracellular membranes. , 1977, Annual review of biochemistry.

[806] M. J. Coon,et al. Cytochrome P-450 purified to apparent homogeneity from phenobarbital-induced rabbit liver microsomes: catalytic activity and other properties. , 1974, Biochemical and biophysical research communications.

[807] K. Einarsson,et al. Evidence against in vitro modulation of rat liver cholesterol 7 alpha-hydroxylase activity by phosphorylation-dephosphorylation: comparison with hydroxymethylglutaryl CoA reductase. , 1986, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry.

[808] D. Nebert,et al. Genes for cytochrome P-450 and their regulation. , 1986, CRC critical reviews in biochemistry.

[809] P. Ortiz de Montellano,et al. Autocatalytic inactivation of plant cytochrome P-450 enzymes: selective inactivation of the lauric acid in-chain hydroxylase from Helianthus tuberosus L. by unsaturated substrate analogs. , 1984, Archives of biochemistry and biophysics.

[810] P. W. V. van Dijck. Negatively charged phospholipids and their position in the cholesterol affinity sequence. , 1979, Biochimica et biophysica acta.

[811] G. Siest,et al. Subcellular distribution of cytochrome P-450 in the brain , 1986, Brain Research.

[812] H. Strobel,et al. Isolation of the membrane-binding peptide of NADPH-cytochrome P-450 reductase. Characterization of the peptide and its role in the interaction of reductase with cytochrome P-450. , 1981, The Journal of biological chemistry.

[813] J. S. Miles,et al. Identification of the primary gene defect at the cytochrome P450 CYP2D locus , 1990, Nature.

[814] R. Croteau,et al. Monoterpene biosynthesis: specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perilla (Perilla frutescens) leaves. , 1990, Archives of biochemistry and biophysics.

[815] W. Lovenberg,et al. Tryptophan hydroxylase. The role of oxygen, iron, and sulfhydryl groups as determinants of stability and catalytic activity. , 1980, The Journal of biological chemistry.

[816] J. Idle,et al. Genetic polymorphism of phenformin 4‐hydroxylation , 1982, Clinical pharmacology and therapeutics.

[817] D. Papahadjopoulos,et al. Effects of proteins on thermotropic phase transitions of phospholipid membranes. , 1975, Biochimica et biophysica acta.

[818] M. J. Coon,et al. Separate roles for FMN and FAD in catalysis by liver microsomal NADPH-cytochrome P-450 reductase. , 1981, The Journal of biological chemistry.

[819] T. Kamataki,et al. Purification and properties of cytochrome P-450 from homogenates of human fetal livers. , 1985, Archives of biochemistry and biophysics.

[820] U. Meyer,et al. Genetic polymorphism of human cytochrome P-450 (S)-mephenytoin 4-hydroxylase. Studies with human autoantibodies suggest a functionally altered cytochrome P-450 isozyme as cause of the genetic deficiency. , 1987, Biochemistry.

[821] S. Thorgeirsson,et al. Stable expression of human cytochrome P450IIE1 in mammalian cells: metabolic activation of nitrosodimethylamine and formation of adducts with cellular DNA. , 1992, Cancer research.

[822] G. S. Marks. The effects of chemicals on hepatic heme biosynthesis , 1981 .

[823] J. Casazza,et al. The metabolism of acetone in rat. , 1984, The Journal of biological chemistry.

[824] G. Monod,et al. Potentiation of βNF induction of cytochrome P4501A1 by glucocorticoids in primary culture of rainbow trout hepatocytes , 1992 .

[825] L. Orci,et al. The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins). , 1982, Endocrine reviews.

[826] G. Divincenzo,et al. The relative neurotoxicity of methyl-n-butyl ketone, n-hexane and their metabolites. , 1980, Toxicology and applied pharmacology.

[827] M. New,et al. Adrenal glomerulosa function in patients with dexamethasone-suppressible hyperaldosteronism. , 1981, The Journal of clinical endocrinology and metabolism.

[828] M. Penno,et al. Monogenic control of variations in antipyrine metabolite formation. New polymorphism of hepatic drug oxidation. , 1983, The Journal of clinical investigation.

[829] L. Weiss,et al. Cell and tissue biology : a textbook of histology , 1988 .

[830] J. Schenkman,et al. Responses to insulin by two forms of rat hepatic microsomal cytochrome P-450 that undergo major (RLM6) and minor (RLM5b) elevations in diabetes. , 1987, The Journal of biological chemistry.

[831] O. Sugita,et al. Partial purification of cytochrome P450 from rat brain and demonstration of estradiol hydroxylation. , 1987, Biochemical and biophysical research communications.

[832] Y. Fujii‐Kuriyama,et al. Evidence for frequent gene conversion in the steroid 21-hydroxylase P-450(C21) gene: implications for steroid 21-hydroxylase deficiency. , 1988, American journal of human genetics.

[833] U. Meyer,et al. The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats. , 1989, Biochemistry.

[834] R. Philpot,et al. Reconstitution of the rabbit pulmonary microsomal mixed-function oxidase system from solubilized components. , 1975, Drug metabolism and disposition: the biological fate of chemicals.

[835] M. Tsubaki,et al. Characterization of two cysteine residues in cytochrome P-450scc: chemical identification of the heme-binding cysteine residue. , 1986, Biochimica et biophysica acta.

[836] P. Thomas,et al. Purification and characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls☆ , 1982 .

[837] M. Ronis,et al. Initial characterization of a constitutive cytochrome P-450 isoenzyme in rainbow trout liver , 1989 .

[838] J. Goldstein,et al. Characterization of a cDNA for rat P-450g, a highly polymorphic, male-specific cytochrome in the P-450IIC subfamily. , 1989, Biochemistry.

[839] E. Bresnick,et al. Induction of benzpyrene hydroxylase in fetal liver explants by flavones and phenobarbital. , 1973, Biochemical pharmacology.

[840] B. Milleron,et al. 1,25(OH)2D2 production by T lymphocytes and alveolar macrophages recovered by lavage from normocalcemic patients with tuberculosis. , 1990, The Journal of clinical investigation.

[841] H. DeLuca. The vitamin D story: a collaborative effort of basic science and clinical medicine 1 , 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[842] W. Schwarze,et al. Fluorescent energy transfer measurements on fluorescein isothiocyanate modified cytochrome P-450 LM2. , 1983, Biochemical and biophysical research communications.

[843] M. J. Coon,et al. Rabbit nasal cytochrome P-450 NMa has high activity as a nicotine oxidase. , 1990, Biochemical and biophysical research communications.

[844] J. Gustafsson,et al. Distribution and Regulation of 5α-Androstane-3β,17β- Diol Hydroxylase in the Rat Central Nervous System* , 1989 .

[845] B. Hammock. NADPH dependent epoxidation of methyl farnesoate to juvenile hormone in the cockroach Blaberus giganteus L. , 1975, Life sciences.

[846] S. Wrighton,et al. Isolation and characterization of human fetal liver cytochrome P450HLp2: a third member of the P450III gene family. , 1989, Archives of biochemistry and biophysics.

[847] W. Pratt. Interaction of hsp90 with steroid receptors: organizing some diverse observations and presenting the newest concepts , 1990, Molecular and Cellular Endocrinology.

[848] F. Wiebel,et al. Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor. , 1990, Chemico-biological interactions.

[849] C. Mendelson,et al. Estrogen formation in stromal cells of adipose tissue of women: induction by glucocorticosteroids. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[850] K. Holm,et al. Isolation by ion-exchange high performance liquid chromatography of rabbit liver cytochrome P-450 with regioselectivity for omega-hydroxylation of prostaglandins. , 1985, The Journal of biological chemistry.

[851] O. Hankinson,et al. Analysis of two benzo[a]pyrene‐resistant mutants of the mouse hepatoma Hepa‐1 P(1)450 gene via cDNA expression in yeast. , 1987, The EMBO journal.

[852] Y. Fujii‐Kuriyama,et al. A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[853] J. Cunningham,et al. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. , 1992, The Journal of biological chemistry.

[854] A. Brownie,et al. Cholesterol side-chain cleavage in the rat adrenal cortex: isolation of a cycloheximide-sensitive activator peptide. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[855] M. Ishiguro,et al. A single amino acid substitution converts cytochrome P450(14DM) to an inactive form, cytochrome P450SG1: complete primary structures deduced from cloned DNAS. , 1988, Biochemical and biophysical research communications.

[856] J. Lambeth,et al. Phosphatidylcholine vesicle reconstituted cytochrome P-450scc. Role of the membrane in control of activity and spin state of the cytochrome. , 1980, The Journal of biological chemistry.

[857] C. Mendelson,et al. Preparation and characterization of polyclonal and monoclonal antibodies against human aromatase cytochrome P-450 (P-450AROM), and their use in its purification. , 1985, Archives of biochemistry and biophysics.

[858] J. Salaün,et al. Induction by manganese, ethanol, phenobarbital, and herbicides of microsomal cytochrome P-450 in higher plant tissues. , 1979, Archives of biochemistry and biophysics.

[859] E. Bresnick,et al. Interaction of the 4 S polycyclic aromatic hydrocarbon-binding protein with the cytochrome P-450c gene. , 1987, Archives of biochemistry and biophysics.

[860] F. Gonzalez,et al. Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme. , 1986, The Journal of biological chemistry.

[861] G. Gibson,et al. Chemical modification of the histidine residues of purified hepatic cytochrome P-450: influence on substrate binding and the haemoprotein spin state. , 1986, Chemico-biological interactions.

[862] J. Benítez,et al. Aminopyrine N‐demethylase activity in human liver microsomes , 1990, Clinical pharmacology and therapeutics.

[863] S. Imaoka,et al. Age-dependent expression of cytochrome P-450s in rat liver. , 1991, Biochimica et biophysica acta.

[864] M. Draznin,et al. Direct analysis of CYP21B genes in 21-hydroxylase deficiency using polymerase chain reaction amplification. , 1990, Molecular endocrinology.

[865] M. Komori,et al. Purification and characterization of cytochrome P-450 with high affinity for 7-alkoxycoumarins. , 1984, Journal of biochemistry.

[866] S. Bloom,et al. Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[867] S. Imaoka,et al. Purification and characterization of liver microsomal cytochrome P-450 from untreated male rats. , 1987, Biochimica et biophysica acta.

[868] S. Eden. Age- and sex-related differences in episodic growth hormone secretion in the rat. , 1979, Endocrinology.

[869] Y. Yasukochi,et al. NADPH-cytochrome c (P-450) reductase. Spectrophotometric and stopped flow kinetic studies on the formation of reduced flavoprotein intermediates. , 1979, The Journal of biological chemistry.

[870] P. Beaune,et al. Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. , 1990, The Journal of pharmacology and experimental therapeutics.

[871] S. Kawabata,et al. Purification and characterization of three male-specific and one female-specific forms of cytochrome P-450 from rat liver microsomes. , 1986, Journal of biochemistry.

[872] R. Kato,et al. Sex-related differences in drug metabolism. , 1974, Drug metabolism reviews.

[873] F. Oesch,et al. V79 Chinese hamster cells genetically engineered for stable expression of cytochromes P450. , 1991, Methods in enzymology.

[874] A. Lupo,et al. Human aldolase A gene. Structural organization and tissue-specific expression by multiple promoters and alternate mRNA processing. , 1988, European journal of biochemistry.

[875] M. P. Arlotto,et al. Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1. , 1990, Carcinogenesis.

[876] F. Guengerich,et al. Rat liver cytochrome P-450 isozymes as catalysts of aldrin epoxidation in reconstituted monooxygenase systems and microsomes. , 1987, Biochemical pharmacology.

[877] J. A. Svoboda,et al. Ecdysone 20‐monooxygenase in mitochondria and microsomes of Manduca sexta (L.) Midgut: Is the dual localization real? , 1985 .

[878] J. W. Gronwald,et al. In vitro hydroxylation of bentazon by microsomes from naphthalic anhydride-treated corn shoots. , 1990, Biochemical and biophysical research communications.

[879] Y. Nisimoto. Localization of cytochrome c-binding domain on NADPH-cytochrome P-450 reductase. , 1986, The Journal of biological chemistry.

[880] P. Thomas,et al. Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics. , 1983, The Journal of biological chemistry.

[881] I. Turko,et al. Cross-linking studies of adrenocortical cytochrome P-450scc. Evidence for a covalent complex with adrenodoxin and localization of the adrenodoxin-binding domain. , 1985, Biochimica et biophysica acta.

[882] J. Staunton,et al. Adult male-specific and neonatally programmed rat hepatic P-450 forms RLM2 and 2a are not dependent on pulsatile plasma growth hormone for expression. , 1988, The Journal of biological chemistry.

[883] R. Dixon,et al. Membrane-bound hydroxylases in elicitor-treated bean cells. Rapid induction of the synthesis of prolyl hydroxylase and a putative cytochrome P-450. , 1986, European journal of biochemistry.

[884] F. Gonzalez,et al. Molecular genetics of the P-450 superfamily. , 1990, Pharmacology & therapeutics.

[885] M. Ingelman-Sundberg,et al. Induction of the ethanol-inducible form of rabbit liver microsomal cytochrome P-450 by inhibitors of alcohol dehydrogenase. , 1984, Biochemical and biophysical research communications.

[886] S. Kawato,et al. Conversion of cholesterol to pregnenolone mobilizes cytochrome P-450 in the inner membrane of adrenocortical mitochondria: protein rotation study. , 1990, Journal of biochemistry.

[887] S. Benkovic,et al. Phenylalanine hydroxylase. Correlation of the iron content with activity and the preparation and reconstitution of the apoenzyme. , 1982, The Journal of biological chemistry.

[888] L. Pickle,et al. Lung cancer and the debrisoquine metabolic phenotype. , 1990, Journal of the National Cancer Institute.

[889] R. Feyereisen,et al. Hemolymph ecdysteroid titer and midgut ecdysone 20-monooxygenase activity during the last larval stage of Diploptera punctata , 1986 .

[890] J. Poirier,et al. DEBRISOQUINE METABOLISM IN PARKINSONIAN PATIENTS TREATED WITH ANTIHISTAMINE DRUGS , 1987, The Lancet.

[891] E. Schuetz,et al. Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes. , 1990, Molecular pharmacology.

[892] H. Eizawa,et al. Purification of nitric oxide synthase from rat macrophages. , 1991, The Journal of biological chemistry.

[893] C C Howe,et al. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. , 1980, Science.

[894] M. J. Coon,et al. Kinetics of reduction of cytochrome P-450LM4 in a reconstituted liver microsomal enzyme system. , 1979, The Journal of biological chemistry.

[895] R. Branch,et al. Stereoselective metabolism of mephenytoin in man. , 1981, The Journal of pharmacology and experimental therapeutics.

[896] M. Negishi,et al. Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene. , 1988, The Journal of biological chemistry.

[897] P. Kolattukudy,et al. Midchain hydroxylation of 16-hydroxypalmitic acid by the endoplasmic reticulum fraction from germinating Vicia faba. , 1978, Archives of biochemistry and biophysics.

[898] R. Gray. Evidence that somatomedins mediate the effect of hypophosphatemia to increase serum 1,25-dihydroxyvitamin D3 levels in rats. , 1987, Endocrinology.

[899] D. Nebert,et al. Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture lines. , 1980, The Journal of biological chemistry.

[900] D. Pompon,et al. Maximizing the expression of mammalian cytochrome P-450 monooxygenase activities in yeast cells. , 1990, Biochimie.

[901] D. Kirsch,et al. Nucleotide sequence of cytochrome P450 LIAI (lanosterol 14α-demethylase) from Candida albicans , 1989 .

[902] M. Denison,et al. Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols. , 1986, The Journal of biological chemistry.

[903] M. Agosin,et al. Conversion of α-pinene to α-pinene oxide by rat liver and the bark beetle Dendroctonus terebrans microsomal fractions , 1979 .

[904] R. Vieth,et al. Kinetic behavior of 25-hydroxyvitamin D-1-hydroxylase and -24-hydroxylase in rat kidney mitochondria. , 1979, The Journal of biological chemistry.

[905] T. Aoyama,et al. Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[906] C. Hunt,et al. Effect of normal aging on the activity of human hepatic cytochrome P450IIE1. , 1990, Biochemical pharmacology.

[907] R. Mayer,et al. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. , 1985, Biochemical pharmacology.

[908] T. E. Gram. Comparative aspects of mixed function oxidation by lung and liver of rabbits. , 1973, Drug metabolism reviews.

[909] M. Waterman,et al. Ontogeny of adrenal steroid hydroxylases: evidence for cAMP-independent gene expression , 1987, Molecular and Cellular Endocrinology.

[910] M. Marletta,et al. Nitric oxide synthase is a cytochrome P-450 type hemoprotein. , 1992, Biochemistry.

[911] C. Miranda,et al. Comparison of rainbow trout and mammalian cytochrome P450 enzymes: evidence for structural similarity between trout P450 LMC5 and human P450IIIA4. , 1991, Biochemical and biophysical research communications.

[912] R. Cherry,et al. Rotational and lateral diffusion of membrane proteins. , 1979, Biochimica et biophysica acta.

[913] M. Waterman,et al. Discriminatory processing of the precursor forms of cytochrome P-450scc and adrenodoxin by adrenocortical and heart mitochondria. , 1984, The Journal of biological chemistry.

[914] M. Ingelman-Sundberg. Reconstitution of the liver microsomal hydroxylase system into liposomes , 1977, FEBS letters.

[915] J. Leakey,et al. The perinatal development of drug-metabolizing enzymes: what factors trigger their onset? , 1981, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.

[916] H. Strobel,et al. Role of electrostatic interactions in the reaction of NADPH-cytochrome P-450 reductase with cytochromes P-450. , 1988, Archives of biochemistry and biophysics.

[917] M. Eichelbaum,et al. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism. , 1991, American journal of human genetics.

[918] C. Serabjit-Singh,et al. The relationship between increases in the hepatic content of cytochrome P-450, form 5, and in the metabolism of aromatic amines to mutagenic products following treatment of rabbits with phenobarbital. , 1983, Molecular pharmacology.

[919] H. Hauser,et al. Decreased lipid order induced by microsomal cytochrome P-450 and NADPH-cytochrome P-450 reductase in model membranes: fluorescence and electron spin resonance studies. , 1985, Biochemistry.

[920] D. Nebert,et al. Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation , 1986, Molecular and cellular biology.

[921] S. Kawato,et al. Rotation and interactions of genetically expressed cytochrome P-450IA1 and NADPH-cytochrome P-450 reductase in yeast microsomes. , 1991, Biochemistry.

[922] K. Jervell,et al. Studies on the 3-methylcholanthrene induction and carbohydrate repression of rat liver dimethylaminoazobenzene reductase. , 1965, Archives of biochemistry and biophysics.

[923] C. Bradfield,et al. Purification and N-terminal amino acid sequence of the Ah receptor from the C57BL/6J mouse. , 1991, Molecular pharmacology.

[924] J. Wilson. The effect of a pituitary mammotropic tumor on hepatic microsomal drug metabolism in the rat. , 1968, Biochemical pharmacology.

[925] M. Adesnik,et al. Mechanism of induction of cytochrome P-450 by phenobarbital. , 1981, The Journal of biological chemistry.

[926] E. Schuetz,et al. Role of heme in phenobarbital induction of cytochromes P450 and 5-aminolevulinate synthase in cultured rat hepatocytes maintained on an extracellular matrix. , 1990, Archives of biochemistry and biophysics.

[927] H. Oshima,et al. Ketoconazole as a possible universal inhibitor of cytochrome P-450 dependent enzymes: its mode of inhibition. , 1987, Endocrinologia japonica.

[928] C. Nathan,et al. Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages. , 1989, The Journal of biological chemistry.

[929] C. Jefcoate,et al. Expression and function of three cytochrome P-450 isozymes in rat extrahepatic tissues. , 1987, Archives of biochemistry and biophysics.

[930] J. Schenkman,et al. Mechanism of interaction between cytochromes P-450 RLM5 and b5: evidence for an electrostatic mechanism involving cytochrome b5 heme propionate groups. , 1986, Archives of biochemistry and biophysics.

[931] D. Frear,et al. Aryl hydroxylation of diclofop by a cytochrome P450 dependent monooxygenase from wheat , 1989 .

[932] T. Nishino,et al. Spectral properties of a novel cytochrome P-450 of a Saccharomyces cerevisiae mutant SG1. A cytochrome P-450 species having a nitrogenous ligand trans to thiolate. , 1985, Biochemical and biophysical research communications.

[933] T. Sutter,et al. Disruption of the Saccharomyces cerevisiae gene for NADPH-cytochrome P450 reductase causes increased sensitivity to ketoconazole. , 1989, Biochemical and biophysical research communications.

[934] J. G. Ghazarian,et al. Inhibition of 25-hydroxyvitamin D 1 alpha-hydroxylase by renal mitochondrial protein kinase-catalyzed phosphorylation. , 1985, Biochemical and biophysical research communications.

[935] H. Strobel,et al. Characterization of cytochrome P450‐dependent dimethylhydrazine metabolism in human colon microsomes , 1991, Cancer.

[936] M. Waterman,et al. Simultaneous transfection of COS-1 cells with mitochondrial and microsomal steroid hydroxylases: incorporation of a steroidogenic pathway into nonsteroidogenic cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[937] H. DeLuca,et al. In vitro production of 1,25-dihydroxyvitamin D3 by rat placental tissue. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[938] S. Imaoka,et al. Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation. , 1990, Archives of biochemistry and biophysics.

[939] A. Jones,et al. Age-related changes in the hepatic endoplasmic reticulum: a quantitative analysis. , 1977, Science.

[940] F. Taylor,et al. Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase. , 1984, Journal of Biological Chemistry.

[941] S. Kennel,et al. Monoclonal antibodies to resistance-related forms of cytochrome P450 in Drosophila melanogaster , 1989 .

[942] A. Dahl,et al. Distribution of microsomal monooxygenases in the rabbit respiratory tract. , 1988, Drug metabolism and disposition: the biological fate of chemicals.

[943] P. Beaune,et al. Isolation and sequence determination of a cDNA clone related to human cytochrome P-450 nifedipine oxidase. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[944] M. Fujita,et al. Ipomeamarone 15-Hydroxylase from Cut-injured and Ceratocystis fimbriata-infected Sweet Potato Root Tissues , 1981 .

[945] H. Glatt,et al. Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of 17β‐estradiol and 2‐aminofluorene in V79 Chinese hamster cells , 1991, Molecular carcinogenesis.

[946] Hao Wang,et al. Purification of adrenodoxin reductase, adrenodoxin, and cytochrome P-450 from adrenal cortex. , 1978, Methods in enzymology.

[947] D. Holtzman,et al. Microsomal Cytochromes in the Immature and Adult Rat Brain , 1980, Journal of neurochemistry.

[948] M. Ohkuma,et al. CYP52 (cytochrome P450alk) multigene family in Candida maltosa: molecular cloning and nucleotide sequence of the two tandemly arranged genes. , 1991, DNA and cell biology.

[949] J. Whitlock,et al. The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis. , 1988, The Journal of biological chemistry.

[950] N. Harada,et al. Cloning of a complete cDNA encoding human aromatase: immunochemical identification and sequence analysis. , 1988, Biochemical and biophysical research communications.

[951] D. Russell,et al. Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. , 1991, The Journal of biological chemistry.

[952] J. Fox,et al. Deficiency of vitamin D metabolites directly stimulates renal 25-hydroxyvitamin D3-1-hydroxylase activity in rats. , 1991, Metabolism: clinical and experimental.

[953] T. Kamataki,et al. Postnatal development of constitutive forms of cytochrome P-450 in liver microsomes of male and female rats. , 1984, Biochemical pharmacology.

[954] B. Dvorchik,et al. Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: comparison with hepatic aminopyrine N-demethylation. , 1979, The Journal of pharmacology and experimental therapeutics.

[955] C. Wolf,et al. The rabbit pulmonary monooxygenase system. Catalytic differences between two purified forms of cytochrome P-450 in the metabolism of benzo(a)pyrene. , 1979, The Journal of biological chemistry.

[956] B. Turgeon,et al. Isolation of a phytoalexin-detoxification gene from the plant pathogenic fungus Nectria haematococca by detecting its expression in Aspergillus nidulans. , 1988, Gene.

[957] D G Grahame-Smith,et al. Adenosine 3',5'-monophosphate as the intracellular mediator of the action of adrenocorticotropic hormone on the adrenal cortex. , 1967, The Journal of biological chemistry.

[958] R. Kato,et al. The regulation by growth hormone of microsomal testosterone 6 beta-hydroxylase in male rat livers. , 1986, Journal of biochemistry.

[959] J. Mathis,et al. Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I. , 1989, Archives of biochemistry and biophysics.

[960] D. Stevenson,et al. Mechanistic consideration of P-450 dependent enzymic reactions: studies on oestriol biosynthesis , 1988 .

[961] Y. Nogi,et al. Expression of a human P-450IIC gene in yeast cells using galactose-inducible expression system. , 1989, Molecular pharmacology.

[962] B. de Kruyff,et al. The effect of the polar headgroup on the lipid-cholesterol interaction: a monolayer and differential scanning calorimetry study. , 1973, Biochimica et biophysica acta.

[963] F. Althaus,et al. Drug-mediated induction of cytochrome(s) P-450 and drug metabolism in cultured hepatocytes maintained in chemically defined medium. , 1979, The Journal of biological chemistry.

[964] M. J. Coon,et al. Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation. , 1970, The Journal of biological chemistry.

[965] G. J. Blomquist,et al. Evidence for a sex pheromone metabolizing cytochrome P‐450 mono‐oxygenase in the housefly , 1987 .

[966] R. Tuckey,et al. Purification and analysis of phospholipids in the inner mitochondrial membrane fraction of bovine corpus luteum, and properties of cytochrome P-450scc incorporated into vesicles prepared from these phospholipids. , 1985, European journal of biochemistry.

[967] C. Miranda,et al. Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. , 1989, Archives of biochemistry and biophysics.

[968] A. Rahier,et al. Properties and structural requirements for substrate specificity of cytochrome P-450-dependent obtusifoliol 14 alpha-demethylase from maize (Zea mays) seedlings. , 1991, The Biochemical journal.

[969] J. Bleiberg,et al. INDUSTRIALLY ACQUIRED PORPHYRIA. , 1964, Archives of dermatology.

[970] I. Issemann,et al. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators , 1990, Nature.

[971] P. Thomas,et al. Metabolism of carcinogenic nitrosamines by rat nasal mucosa and the effect of diallyl sulfide. , 1991, Cancer research.

[972] R. Kato,et al. Thyroid hormone suppression of hepatic levels of phenobarbital-inducible P-450b and P-450e and other neonatal P-450s in hypophysectomized rats. , 1989, Biochemical and biophysical research communications.

[973] J. Hevel,et al. Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein. , 1991, The Journal of biological chemistry.

[974] T. Kamataki,et al. Cytochrome P-450 as a determinant of sex difference of drug metabolism in the rat. , 1982, Xenobiotica; the fate of foreign compounds in biological systems.

[975] Ortiz de Montellano,et al. Cytochrome P-450: Structure, Mechanism, and Biochemistry , 1986 .

[976] P. Guzelian,et al. Ascorbic acid deficiency and cytochrome P-450 in adult rat hepatocytes in primary monolayer culture. , 1979, Archives of biochemistry and biophysics.

[977] D. Waxman,et al. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. , 1986, The Journal of biological chemistry.

[978] J. Mathis,et al. Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis. , 1989, The Journal of biological chemistry.

[979] L. Valladares,et al. Induction of testicular aromatization by luteinizing hormone in mature rats. , 1979, Endocrinology.

[980] K. Kitani. Neurohumoral control of liver functions during aging. , 1988, Gerontology.

[981] Y. Ichikawa,et al. Modification of a lysine residue of adrenodoxin reductase, essential for complex formation with adrenodoxin. , 1984, Biochimica et biophysica acta.

[982] L. Narhi,et al. Phenobarbital induction of a soluble cytochrome P-450-dependent fatty acid monooxygenase in Bacillus megaterium. , 1982, The Journal of biological chemistry.

[983] E. Ford,et al. Genetic polymorphism , 2020, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[984] S. Povey,et al. Cloning, experession and chromosomal localization of a member of the human cytochrome P450IIC gene sub‐family , 1989, Annals of human genetics.

[985] B. Middleditch,et al. Enzymatic formation of (20R, 22R)-20,22-dihydroxycholesterol from cholesterol and a mixture of 16O2 and 18O2: random incorporation of oxygen atoms. , 1974, Biochemical and biophysical research communications.

[986] R. Gasser,et al. Primary structures of cytochrome P-450 isozyme 5 from rabbit and rat and regulation of species-dependent expression and induction in lung and liver: identification of cytochrome P-450 gene subfamily IVB. , 1989, Molecular pharmacology.

[987] M. P. Arlotto,et al. Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. , 1987, Archives of biochemistry and biophysics.

[988] W. Schwarze,et al. Active site model of cytochrome P-450 LM2. , 1988, Biochemical and biophysical research communications.

[989] E. Schuetz,et al. Divergent effects of cycloheximide on the induction of class II and class III cytochrome P450 mRNAs in cultures of adult rat hepatocytes. , 1990, Archives of biochemistry and biophysics.

[990] N. Harada,et al. Structural characterization of the human estrogen synthetase (aromatase) gene. , 1990, Biochemical and biophysical research communications.

[991] E. Sackmann,et al. Spin labels as enzyme substrates. Heterogeneous lipid distribution in liver microsomal membranes. , 1973, Biochimica et biophysica acta.

[992] P. White,et al. Distribution of deletions and seven point mutations on CYP21B genes in three clinical forms of steroid 21-hydroxylase deficiency. , 1991, American journal of human genetics.

[993] O. Jones,et al. INDUCTION OF CYTOCHROME P‐450 IN INTACT MUNG BEANS , 1984 .

[994] J. Goldstein,et al. Differential induction of two 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible forms of cytochrome P-450 in extrahepatic versus hepatic tissues. , 1984, Molecular pharmacology.

[995] P. Watkins,et al. Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[996] S. Sjöstedt,et al. On the stereospecificity of microsomal "26"-hydroxylation in bile acid biosynthesis. , 1978, The Journal of biological chemistry.

[997] C. Gomez-Sanchez,et al. Glucocorticoid-suppressible aldosteronism: a disorder of the adrenal transitional zone. , 1988, The Journal of clinical endocrinology and metabolism.

[998] D. Williams,et al. Sex differences in cytochrome P-450 isozyme composition and activity in kidney microsomes of mature rainbow trout. , 1986, Biochemical pharmacology.

[999] T. Bergman,et al. Characterization of mitochondrial cytochromes P-450 from pig kidney and liver catalysing 26-hydroxylation of 25-hydroxyvitamin D3 and C27 steroids. , 1991, The Biochemical journal.

[1000] G. Daum,et al. Lipids of mitochondria. , 1985, Biochimica et biophysica acta.

[1001] M. Tohyama,et al. Presence of sex difference of cytochrome P-450 in the rat preoptic area and hypothalamus with reference to coexistence with oxytocin , 1990, Brain Research.

[1002] T. Shimada,et al. Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. , 1991, Chemical research in toxicology.

[1003] D. Nebert,et al. Autoregulation plus upstream positive and negative control regions associated with transcriptional activation of the mouse P1(450) gene. , 1985, Nucleic acids research.

[1004] J. Noordhoek,et al. Comparative cytotoxicity of bromobenzene in primary cultures of rat and hamster hepatocytes and its relation to biotransformation. , 1991, Toxicology in vitro : an international journal published in association with BIBRA.

[1005] S. Wrighton,et al. Purification and characterization of ethanol-inducible human hepatic cytochrome P-450HLj. , 1987, Archives of biochemistry and biophysics.

[1006] D. Williams,et al. Purified form of cytochrome P-450 from rainbow trout with high activity toward conversion of aflatoxin B1 to aflatoxin B1-2,3-epoxide. , 1983, Cancer research.

[1007] E. Bresnick,et al. Induction of cytochrome P450IA1 in rat hepatoma cell by polycyclic hydrocarbons and a dioxin. , 1990, Biochemical pharmacology.

[1008] P. Rangarajan,et al. Dexamethasone negatively regulates phenobarbitone-activated transcription but synergistically enhances cytoplasmic levels of cytochrome P-450b/e messenger RNA. , 1990, The Journal of biological chemistry.

[1009] B. Lake,et al. Induction of lauric acid hydroxylation and maintenance of cytochrome P-450 content by clofibrate in primary cultures of rat hepatocytes. , 1983, Life sciences.

[1010] W. Staib,et al. Differential down-regulation and induction responses of testicular steroidogenic cytochromes P-450(cscc) and P-450(C17α) to human choriogonadotropin , 1986, Bioscience reports.

[1011] J. Gustafsson,et al. Growth hormone regulation of the cytochrome P-450IIC subfamily in the rat: inductive, repressive, and transcriptional effects on P-450f (IIC7) and P-450PB1 (IIC6) gene expression. , 1990, Molecular pharmacology.

[1012] M. Waterman,et al. Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. , 1988, Annual review of physiology.

[1013] A. Burger,et al. In vitro studies on potential selective and irreversible inhibitors of enzymes involved in the biosynthesis of ecdysone , 1987 .

[1014] R. Magolda,et al. Lanosterol 14 alpha-methyl demethylase. Isolation and characterization of the third metabolically generated oxidative demethylation intermediate. , 1991, The Journal of biological chemistry.

[1015] I. Huhtaniemi,et al. Differential response of luteinizing hormone receptor and steroidogenic enzyme gene expression to human chorionic gonadotropin stimulation in the neonatal and adult rat testis. , 1990, Endocrinology.

[1016] T. Iyanagi,et al. Studies on the microsomal mixed function oxidase system: redox properties of detergent-solubilized NADPH-cytochrome P-450 reductase. , 1978, Biochemistry.

[1017] R. Kato,et al. Thyroid hormone and activities of drug-metabolizing enzymes and electron transport systems of rat liver microsomes. , 1968, Molecular pharmacology.

[1018] H. Strobel,et al. Aging affects the drug metabolism systems of rat liver, kidney, colon and lung in a differential fashion , 1986, Experimental Gerontology.

[1019] R. Evans,et al. Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[1020] A. Triolo,et al. Induction of aryl hydrocarbon hydroxylase and forestomach tumors ben benzo(a)pyrene. , 1977, Cancer research.

[1021] R. Tukey,et al. Structural gene products of the Ah locus. Transcriptional regulation of cytochrome P1-450 and P3-450 mRNA levels by 3-methylcholanthrene. , 1984, Molecular pharmacology.

[1022] P. Watkins,et al. Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients. , 1989, The Journal of clinical investigation.

[1023] K. Griffin,et al. Variations in hepatic progesterone 21-hydroxylase activity reflect differences in the microsomal concentration of rabbit cytochrome P-450 1. , 1985, Archives of biochemistry and biophysics.

[1024] P. Hylemon,et al. Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat. , 1991, The Journal of biological chemistry.

[1025] F. Murad,et al. Purification and characterization of a human NO synthase. , 1991, Biochemical and biophysical research communications.

[1026] C. West. Hydroxylases, Monooxygenases, and Cytochrome P-450 , 1980 .

[1027] C. Bonfils,et al. Expression of five forms of microsomal cytochrome P-450 in primary cultures of rabbit hepatocytes treated with various classes of inducers. , 1987, Biochemical pharmacology.

[1028] M. Maugras,et al. The hepatic cytochrome level in the cat (Felis catus): normal value and variations in relation to some biological parameters. , 1979, Comparative biochemistry and physiology. B, Comparative biochemistry.

[1029] Z. Hochberg,et al. 11 Beta-hydroxylase deficiency congenital adrenal hyperplasia: update of prenatal diagnosis. , 1988, The Journal of clinical endocrinology and metabolism.

[1030] M. Ingelman-Sundberg,et al. Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies. , 1988, Biochemistry.

[1031] K. Krauter,et al. Expression of cytochromes P-450c and P-450d mRNAs in cultured rat hepatocytes. 3-Methylcholanthrene induction is regulated primarily at the post-transcriptional level. , 1988, The Journal of biological chemistry.

[1032] P. Jurtshuk,et al. Cytochrome P-450 involvement in the oxidation of n-octane b cell-free extracts of Corynebacterium sp. strain 7E1C. , 1968, The Journal of biological chemistry.

[1033] M. Farrall,et al. The gene CYP3 encoding P450pcn1 (nifedipine oxidase) is tightly linked to the gene COL1A2 encoding collagen type 1 alpha on 7q21-q22.1. , 1988, American journal of human genetics.

[1034] T. Kamataki,et al. Further studies on the persistence of neonatal androgen imprinting on sex-specific cytochrome P-450, testosterone and drug oxidations. , 1987, Japanese journal of pharmacology.

[1035] C. Maltoni,et al. EXPERIMENTAL CONTRIBUTIONS IN IDENTIFYING BRAIN POTENTIAL CARCINOGENS IN THE PETROCHEMICAL INDUSTRY , 1982, Annals of the New York Academy of Sciences.

[1036] P. C. Rath,et al. Age-related changes in the expression of cytochrome P-450 (b+e) gene in the rat after phenobarbitone administration. , 1988, Biochemical and biophysical research communications.

[1037] M. Grant,et al. The influence of culture medium composition on drug metabolising enzyme activities of the human liver derived Hep G2 cell line , 1988, FEBS letters.

[1038] J. Stegeman,et al. Sex differences in hepatic monooxygenases in winter flounder (Pseudopleuronectes americanus) and scup (Stenotomus chrysops) and regulation of P450 forms by estradiol. , 1991, The Journal of experimental zoology.

[1039] H C Pitot,et al. Drug metabolism and effects of carcinogens in cultured hepatic cells. , 1979, Pharmacological reviews.

[1040] C. Mougin,et al. Hydroxylation and N-demethylation of chlorotoluron by wheat microsomal enzymes , 1990 .

[1041] J. Gustafsson,et al. Purification, characterization, and pituitary regulation of the sex-specific cytochrome P-450 15 beta-hydroxylase from liver microsomes of untreated female rats. , 1984, The Journal of biological chemistry.

[1042] S. Venkatesan,et al. On the mechanism for the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, of cholesterol 7alpha-hydroxylase and of acyl-coenzyme A:cholesterol acyltransferase by free cholesterol. , 1978, Biochimica et biophysica acta.

[1043] P. Hall,et al. Cytochrome P-450 from bovine adrenocortical mitochondria: an enzyme for the side chain cleavage of cholesterol. II. Subunit structure. , 1973, The Journal of biological chemistry.

[1044] J. Falck,et al. Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[1045] F. Durst,et al. Two cytochrome P-450 isoforms catalysing O-de-ethylation of ethoxycoumarin and ethoxyresorufin in higher plants. , 1990, The Biochemical journal.

[1046] B. Halliwell. Oxidants and human disease: some new concepts , 1987 .

[1047] W. Rademacher,et al. Tetcyclacis and triazole-type plant growth retardants: Their influence on the biosynthesis of gibberellins and other metabolic processes† , 1987 .

[1048] S. Kawato,et al. Rotation of cytochrome P-450. I. Investigations of protein-protein interactions of cytochrome P-450 in phospholipid vesicles and liver microsomes. , 1982, The Journal of biological chemistry.

[1049] J. Kellis,et al. Purification and characterization of human placental aromatase cytochrome P-450. , 1987, The Journal of biological chemistry.

[1050] J. Wergedal,et al. Regulation of serum 1alpha,25-dihydroxyvitamin D3 by calcium and phosphate in the rat , 1975, Science.

[1051] J. Chiang. Interaction of purified microsomal cytochrome P-450 with cytochrome b5. , 1981, Archives of biochemistry and biophysics.

[1052] H. Glatt,et al. Genetically engineered V79 Chinese hamster cells metabolically activate the cytostatic drugs cyclophosphamide and ifosfamide. , 1990, Environmental health perspectives.

[1053] Y. Ichikawa,et al. Purification of cytochrome P-450D1α (25-hydroxyvitamin D3-1α-hydroxylase) of bovine kidney mitochondria , 1982 .

[1054] J. Lambeth. Cytochrome P-450scc. Cardiolipin as an effector of activity of a mitochondrial cytochrome P-450. , 1981, The Journal of biological chemistry.

[1055] G. Stein,et al. Die Elimination von Coffein und Metamizol zur in-vivo-Charakterisierung Cytochrom P-450-abhängiger Biotransformationsreaktionen beim alten Menschen , 1985 .

[1056] Y. Funae,et al. High-performance liquid chromatography technique for resolving multiple forms of hepatic membrane-bound cytochrome P-450. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[1057] P. White,et al. Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiency. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[1058] F. Gonzalez,et al. Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA. , 1986, The Journal of biological chemistry.

[1059] S. Kawabata,et al. A mutant rat strain deficient in induction of a phenobarbital-inducible form of cytochrome P-450 in liver microsomes. , 1988, Journal of biochemistry.

[1060] H. Murakami,et al. Primary structure of Saccharomyces cerevisiae NADPH-cytochrome P450 reductase deduced from nucleotide sequence of its cloned gene. , 1988, Journal of biochemistry.

[1061] D. Matthews,et al. Solubilization and Reconstitution of Pisatin Demethylase, a Cytochrome P-450 from the Pathogenic Fungus Nectria haematococca. , 1984, Plant physiology.

[1062] R. Ebel,et al. Temperature dependence of cytochrome P-450 reduction. A model for NADPH-cytochrome P-450 reductase:cytochrome P-450 interaction. , 1976, The Journal of biological chemistry.

[1063] P. White,et al. Structure of human steroid 21-hydroxylase genes. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[1064] J. Purvis,et al. Studies of cytochrome P-450 in testis microsomes. , 1973, Archives of biochemistry and biophysics.

[1065] G. Castañeda-Hernández,et al. Pharmacokinetics of Nifedipine Slow Release Tablet in Mexican Subjects: Further Evidence for an Oxidation Polymorphism , 1989, Journal of clinical pharmacology.

[1066] K. Yanagibashi,et al. Complete amino acid sequence of 21-hydroxylase cytochrome P-450 from porcine adrenal microsomes. , 1987, Archives of biochemistry and biophysics.

[1067] J. Wilson,et al. The expression of a functional cDNA encoding the chicken cytochrome P-450arom (aromatase) that catalyzes the formation of estrogen from androgen. , 1988, The Journal of biological chemistry.

[1068] H. Mantsch,et al. Infrared spectroscopic analysis of salt bridge formation between cytochrome b5 and cytochrome c. , 1988, Biochemistry.

[1069] D. Waxman,et al. Hepatic P450 expression in hypothyroid rats: differential responsiveness of male-specific P450 forms 2a (IIIA2), 2c (IIC11), and RLM2 (IIA2) to thyroid hormone. , 1991, Molecular endocrinology.

[1070] J. I. Pedersen,et al. Properties of a reconstituted vitamin D3 25-hydroxylase from rat liver mitochondria. , 1980, The Journal of biological chemistry.

[1071] B J Blaauboer,et al. Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities. , 1991, Biochemical pharmacology.

[1072] M. Romkes,et al. Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily. , 1991, Biochemistry.

[1073] N. Orme-Johnson,et al. Beef adrenal cortical cytochrome P-450 which catalyzes the conversion of cholesterol to pregnenolone. Oxidation-reduction potentials of the free, steroid-complexed, and adrenodoxin-complexed P-450. , 1981, The Journal of biological chemistry.

[1074] H. DeLuca,et al. Evidence that increased circulating 1 alpha, 25-dihydroxyvitamin D is the probable cause for abnormal calcium metabolism in sarcoidosis. , 1979, The Journal of clinical investigation.

[1075] R. Feyereisen,et al. Development of microsomal cytochrome P-450 monooxygenases during the last larval instar of the locust, Locusta migratoria: Correlation with the hemolymph 20-hydroxyecdysone titer , 1980, Molecular and Cellular Endocrinology.

[1076] R. Tukey,et al. Structural gene product of the [Ah] complex. Evidence for transcriptional control of cytochrome P1-450 induction by use of a cloned DNA sequence. , 1981, The Journal of biological chemistry.

[1077] I. Z. Ades,et al. Regulation of production of delta-aminolaevulinate synthase in tissues of chick embryos. Effects of porphyrogenic agents and of haem precursors. , 1989, The Biochemical journal.

[1078] A. Fulco,et al. Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. , 1975, Biochimica et biophysica acta.

[1079] J. Rosazza,et al. Biocatalysis in natural products chemistry , 1984 .

[1080] J. Potts,et al. The 4-hydroxylation of cinnamic acid by sorghum microsomes and the requirement for cytochrome P-450. , 1974, The Journal of biological chemistry.

[1081] F. Guengerich,et al. Altered regulation of cytochrome P-450 enzymes in choline-deficient cirrhotic male rat liver: impaired regulation and activity of the male-specific androst-4-ene-3,17-dione 16 alpha-hydroxylase, cytochrome P-450UT-A, in hepatic cirrhosis. , 1987, Molecular pharmacology.

[1082] A. Kandutsch,et al. Biological activity of some oxygenated sterols. , 1978, Science.

[1083] P. Cohen. Protein phosphorylation and hormone action — An overview , 1983 .

[1084] N. Serizawa,et al. Microbial hydroxylation of ML-236B (compactin). Studies on microorganisms capable of 3 beta-hydroxylation of ML-236B. , 1983, The Journal of antibiotics.

[1085] M. Noshiro,et al. Molecular cloning of cDNA for vitamin D3 25‐hydroxylase from rat liver mitochondria , 1990, FEBS letters.

[1086] D. W. Ovenall,et al. Microbial transformation of precocene II: oxidative reactions by Streptomyces griseus , 1987, Applied and environmental microbiology.

[1087] R. Strong,et al. Phosphorylation of ferredoxin and regulation of renal mitochondrial 25-hydroxyvitamin D-1 alpha-hydroxylase activity in vitro. , 1989, Journal of Biological Chemistry.

[1088] G. S. Boyd,et al. The catalytic cycle of cytochrome P-450scc and intermediates in the conversion of cholesterol to pregnenolone. , 1984, European journal of biochemistry.

[1089] J. Williams,et al. Evaluation of a human hepatoma cell line as a target cell in genetic toxicology. , 1983, Mutation research.

[1090] M. Boyd,et al. The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol. , 1982, Molecular pharmacology.

[1091] A Poland,et al. 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. , 1982, Annual review of pharmacology and toxicology.

[1092] J. Schenkman,et al. Chemical characterization of protein-protein interactions between cytochrome P-450 and cytochrome b5. , 1985, The Journal of biological chemistry.

[1093] A. Dahl,et al. Nasal cavity enzymes involved in xenobiotic metabolism: effects on the toxicity of inhalants. , 1991, Critical reviews in toxicology.

[1094] C. Elferink,et al. Characterization of multiple forms of the Ah receptor: recognition of a dioxin-responsive enhancer involves heteromer formation. , 1991, Biochemistry.

[1095] F. Oesch,et al. First evidence of cytochrome P-450 induction in the mouse brain by phenytoin , 1988, Neuroscience Letters.

[1096] B C Finzel,et al. The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450. , 1985, The Journal of biological chemistry.

[1097] M. J. Coon,et al. Sedimentation and other properties of the reconstituted liver microsomal mixed-function oxidase system containing cytochrome P-450, reduced triphosphopyridine nucleotide-cytochrome P-450 reductase, and phosphatidylcholine. , 1973, Molecular pharmacology.

[1098] D. Nelson,et al. Evolution of the cytochrome P450 genes. , 1989, Xenobiotica; the fate of foreign compounds in biological systems.

[1099] N. Ikekawa,et al. Substrate specificity of adrenocortical cytochrome P-450SCC. II. Effect of structural modification of cholesterol A/B ring on their side chain cleavage reaction. , 1982, Journal of steroid biochemistry.

[1100] B J Blaauboer,et al. The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers. , 1990, Biochemical pharmacology.

[1101] F. Gonzalez,et al. Stable expression of human cytochrome P450IA2 cDNA in a human lymphoblastoid cell line: Role of the enzyme in the metabolic activation of aflatoxin B1 , 1990, Molecular carcinogenesis.

[1102] S. Imaoka,et al. Suppression of hepatic levels of an ethanol-inducible P-450DM/j by growth hormone: relationship between the increased level of P-450DM/j and depletion of growth hormone in diabetes. , 1989, Molecular pharmacology.

[1103] J. Trzăskos,et al. Microsomal enzymes of cholesterol biosynthesis. Purification of lanosterol 14 alpha-methyl demethylase cytochrome P-450 from hepatic microsomes. , 1986, The Journal of biological chemistry.

[1104] G. Padmanaban,et al. Studies on the biosynthesis of cytochrome P-450 in rat liver--a probe with phenobarbital. , 1979, Archives of biochemistry and biophysics.

[1105] P. Ortiz de Montellano,et al. Differential inactivation of plant lauric acid omega- and in-chain-hydroxylases by terminally unsaturated fatty acids. , 1988, Archives of biochemistry and biophysics.

[1106] R. Tukey,et al. Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[1107] R. Chanderbhan,et al. Cholesterol ester hydrolase and sterol carrier proteins. , 1984, Endocrine research.

[1108] K. Morohashi,et al. Novel cAMP regulatory elements in the promoter region of bovine P-450(11 beta) gene. , 1990, Journal of biochemistry.

[1109] H. de Verneuil,et al. Study of anaesthetic agents for their ability to elicit porphyrin biosynthesis in chick embryo liver. , 1983, Biochemical pharmacology.

[1110] J. Gustafsson,et al. Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor. , 1988, Biochemical and biophysical research communications.

[1111] E. Baulieu,et al. Pregnenolone and its sulfate ester in the rat brain , 1983, Brain Research.

[1112] H. Taniguchi,et al. Conversion of hepatic microsomal cytochrome P-450 to P-420 upon phosphorylation by cyclic AMP dependent protein kinase. , 1985, Biochemical pharmacology.

[1113] A. Y. Lu,et al. Acetone-inducible cytochrome P-450: purification, catalytic activity, and interaction with cytochrome b5. , 1986, Archives of biochemistry and biophysics.

[1114] J. Lambeth,et al. Cytochrome P-450scc-adrenodoxin complex. Reduction properties of the substrate-associated cytochrome and relation of the reduction states of heme and iron-sulfur centers to association of the proteins. , 1983, The Journal of biological chemistry.

[1115] A. Conney,et al. Intestinal metabolism of phenacetin in the rat: effect of charcoal-broiled beef and rat chow. , 1975, Science.

[1116] F. Gonzalez,et al. A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. , 1991, Chemical research in toxicology.

[1117] R. Walford,et al. Age-related down regulation of hepatic cytochrome P 1-450, P 3-450, catalase and CuZn-superoxide dismutase RNA , 1990, Mechanisms of Ageing and Development.

[1118] A. Conney. Pharmacological implications of microsomal enzyme induction. , 1967, Pharmacological reviews.

[1119] P. Janssen,et al. Mutation in cytochrome P-450-dependent 14 alpha-demethylase results in decreased affinity for azole antifungals. , 1990, Biochemical Society transactions.

[1120] T. Kronbach,et al. Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. , 1989, Molecular pharmacology.

[1121] P. Tennant,et al. Alterations of microsomal monooxygenase system and carcinogen metabolism by streptozotocin-induced diabetes in rats. , 1983, Carcinogenesis.

[1122] F. Gonzalez,et al. Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat. , 1987, Molecular endocrinology.

[1123] B. Masters,et al. Identification of 25,26-dihydroxyvitamin D3 as a rat renal 25-hydroxyvitamin D3 metabolite. , 1981, Biochemistry.

[1124] J. Fry,et al. The in vivo induction of rat hepatic cytochrome P450-dependent enzyme activities and their maintenance in culture. , 1990, Biochemical pharmacology.

[1125] M. Forest,et al. Rearrangements and point mutations of P450c21 genes are distinguished by five restriction endonuclease haplotypes identified by a new probing strategy in 57 families with congenital adrenal hyperplasia. , 1989, The Journal of clinical investigation.

[1126] J. Noordhoek,et al. Biotransformation of scoparone used to monitor changes in cytochrome P450 activities in primary hepatocyte cultures derived from rats, hamsters and monkeys. , 1991, Biochemical pharmacology.

[1127] E. Glover,et al. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene. , 1974, Molecular pharmacology.

[1128] M. Boyd,et al. Covalent binding of metabolites of 4-ipomeanol to rabbit pulmonary and hepatic microsomal proteins and to the enzymes of the pulmonary cytochrome P-450-dependent monooxygenase system. , 1983, The Journal of pharmacology and experimental therapeutics.

[1129] J. Schenkman,et al. Differences in the spectral interactions between NADPH-cytochrome P-450 reductase and a series of cytochrome P-450 enzymes. , 1986, Biochemical and biophysical research communications.

[1130] E. Hodgson,et al. Purification and reconstitution of the cytochrome P-450 monooxygenase system from uninduced mouse liver , 1983 .

[1131] Y. Fujii‐Kuriyama,et al. Primary structure of a cytochrome P-450: coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[1132] K. Jones,et al. Association between induction of aryl hydrocarbon hydroxylase and depression of uroporphyrinogen decarboxylase activity. , 1977, Research communications in chemical pathology and pharmacology.

[1133] H. Dahlbäck. Characterization of the liver mitochondrial cytochrome P-450 catalyzing the 26-hydroxylation of 5β-cholestane-3α, 7α, 12α-triol , 1988 .

[1134] R. Feyereisen,et al. Expression of the Cytochrome P450 GeneCYP6A1in the Housefly,Musca domestica , 1992 .

[1135] H. Kamin,et al. THE EFFECT OF HIGH SALT CONCENTRATIONS UPON CYTOCHROME C, CYTOCHROME B5, AND IRON‐EDTA REDUCTASE ACTIVITIES OF LIVER MICROSOMAL NADPH‐CYTOCHROME C REDUCTASE * , 1973, Annals of the New York Academy of Sciences.

[1136] W. G. Wood,et al. Comparison of the hepatic mixed function oxidase system of young, adult, and old non-human primates (Macaca nemestrina). , 1985, Biochemical pharmacology.

[1137] P. Sinclair,et al. Uroporphyrinogen oxidation catalyzed by reconstituted cytochrome P450IA2. , 1992, Archives of biochemistry and biophysics.

[1138] R. Tukey,et al. Genetic contributions to the variation among rabbits of liver microsomal deoxycorticosterone synthesis. , 1989, Archives of biochemistry and biophysics.

[1139] S. Loft,et al. Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine. , 1992, Carcinogenesis.

[1140] P. Sinclair,et al. Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem. , 1989, The Biochemical journal.

[1141] E. W. Anacker. The hydrophobic effect: Formation of micelles and biological membranes , 1975 .

[1142] J. Idle,et al. A study of the debrisoquine hydroxylation polymorphism in a Nigerian population. , 1980, Xenobiotica; the fate of foreign compounds in biological systems.

[1143] Y. Fujii‐Kuriyama,et al. Effects of individual mutations in the P-450(C21) pseudogene on the P-450(C21) activity and their distribution in the patient genomes of congenital steroid 21-hydroxylase deficiency. , 1991, Journal of biochemistry.

[1144] P. Beaune,et al. Partial purification of human liver cytochrome P 450. , 1979, Biochemical and biophysical research communications.

[1145] D. Kupfer. Prostanoid Metabolism and Biologically Active Product Formation , 1991 .

[1146] T. Saruta,et al. Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism. , 1991, The Journal of biological chemistry.

[1147] H. DeLuca,et al. Production of 10-oxo-19-nor-25-hydroxyvitamin D3 by solubilized kidney mitochondria from chick and rat. , 1985, Journal of Biological Chemistry.

[1148] M. Hetzel,et al. Metabolic oxidation phenotypes as markers for susceptibility to lung cancer , 1984, Nature.

[1149] F. Oesch,et al. Microsomal epoxide hydrolase. , 1981, Methods in enzymology.

[1150] J. Schenkman,et al. Phosphorylation of cytochrome P450: regulation by cytochrome b5. , 1989, Archives of biochemistry and biophysics.

[1151] R. Coolbaugh,et al. Inhibition of ent-Kaurene Oxidation and Growth by alpha-Cyclopropyl-alpha-(p-methoxyphenyl)-5-pyrimidine Methyl Alcohol. , 1976, Plant physiology.

[1152] A. Fulco,et al. (Omega -2) hydroxylation of fatty acids by a soluble system from bacillus megaterium. , 1974, The Journal of biological chemistry.

[1153] M. J. Coon,et al. Immunochemical identification of cytochrome P-450 isozyme 3a (P-450ALC) in rabbit nasal and kidney microsomes and evidence for differential induction by alcohol. , 1986, Molecular pharmacology.

[1154] H. Gelboin,et al. THE STIMULATORY EFFECT OF 3-METHYLCHOLANTHRENE ON MICROSOMAL AMINO ACID INCORPORATION AND BENZPYRENE HYDROXYLASE ACTIVITY AND ITS INHIBITION BY ACTINOMYCIN D. , 1963, Biochimica et biophysica acta.

[1155] H. Pitot,et al. Phenobarbital-inducible aldehyde dehydrogenase in the rat. cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats. , 1989, The Journal of biological chemistry.

[1156] W. Schwarze,et al. Modification of cytochrome P-450 with fluorescein isothiocyanate. , 1983, Biochimica et biophysica acta.

[1157] C. Nathan,et al. N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine. , 1991, The Journal of biological chemistry.

[1158] D. Nelson,et al. On the membrane topology of vertebrate cytochrome P-450 proteins. , 1988, The Journal of biological chemistry.

[1159] D. Swinney,et al. Regioselective progesterone hydroxylation catalyzed by eleven rat hepatic cytochrome P-450 isozymes. , 1987, Biochemistry.

[1160] K. Morohashi,et al. Site-directed mutagenesis of basic amino acid residues in the extension peptide of P-450(SCC) precursor: effects on the import of the precursor into mitochondria. , 1987, Journal of biochemistry.

[1161] C. Larsson,et al. CYTOCHROME P‐450/420 IN PLANT PLASMA MEMBRANES: A POSSIBLE COMPONENT OF THE BLUE‐LIGHT‐REDUCIBLE FLAVOPROTEIN‐CYTOCHROME COMPLEX * , 1985 .

[1162] O. Mcbride,et al. Human P450PCN1: sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase. , 1988, DNA.

[1163] I. Yamamoto,et al. Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P-450 isozyme. , 1991, The Journal of biological chemistry.

[1164] A. Renwick,et al. Ethnic differences in the pharmacokinetics of oral nifedipine. , 1991, British journal of clinical pharmacology.

[1165] H. Taniguchi,et al. The effects of phosphatase on the components of the cytochrome P-450-dependent microsomal monooxygenase. , 1987, Biochimica et biophysica acta.

[1166] A. Fulco,et al. Induction by barbiturates of a cytochrome P-450-dependent fatty acid monooxygenase in Bacillus megaterium: relationship between barbiturate structure and inducer activity. , 1983, Biochemical and biophysical research communications.

[1167] J. Lambeth,et al. The use of a specific fluorescence probe to study the interaction of adrenodoxin with adrenodoxin reductase and cytochrome P-450scc. , 1987, The Journal of biological chemistry.

[1168] F. Gonzalez,et al. Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1. , 1991, Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.

[1169] A. Frey,et al. Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies , 1987, The Journal of cell biology.

[1170] H. Tjälve,et al. Metabolism of aflatoxin B1 in the bovine olfactory mucosa. , 1989, Carcinogenesis.

[1171] D. Sanglard,et al. Characterization of the alkane-inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis: identification of a new P450 gene family. , 1989, Gene.

[1172] Y. Fujii‐Kuriyama,et al. Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P‐4501A1 gene. , 1992, The EMBO journal.

[1173] M. Relling,et al. Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily. , 1990, The Journal of pharmacology and experimental therapeutics.

[1174] L. Birnbaum. Pharmacokinetic basis of age-related changes in sensitivity to toxicants. , 1991, Annual review of pharmacology and toxicology.

[1175] C. Kozak,et al. The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes. , 1989, DNA.

[1176] M. Maines,et al. Regulation of heme and drug metabolism activities in the brain by manganese. , 1985, Biochemical and biophysical research communications.

[1177] M. Trower,et al. Xenobiotic oxidation by cytochrome P-450-enriched extracts of Streptomyces griseus. , 1988, Biochemical and biophysical research communications.

[1178] J. Miller,et al. The metabolism of methylated aminoazo dyes. I. The demethylation of 3-methyl-4-dimethyl-C14 amino-azobenzene in vivo. , 1952, The Journal of biological chemistry.

[1179] P. Thomas,et al. Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid. , 1985, The Journal of biological chemistry.

[1180] Y. Ohyama,et al. Multi-functional property of rat liver mitochondrial cytochrome P-450. , 1991, Journal of biochemistry.

[1181] A. Parkinson,et al. Reconstitution of testosterone oxidation by purified rat cytochrome P450p (IIIA1). , 1990, Archives of biochemistry and biophysics.

[1182] J. Salaün,et al. Phytochrome-mediated regulation of a monooxygenase hydroxylating cinnamic acid in etiolated pea seedlings , 1978 .

[1183] K Husman,et al. Symptoms of car painters with long-term exposure to a mixture of organic solvents. , 1980, Scandinavian journal of work, environment & health.

[1184] M. Ingelman-Sundberg,et al. Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes. , 1991, Biochemical and biophysical research communications.

[1185] J. Fagan,et al. Transcriptional and post-transcriptional regulation of the genes encoding cytochromes P-450c and P-450d in vivo and in primary hepatocyte cultures. , 1988, The Journal of biological chemistry.

[1186] S. Imaoka,et al. Purification and characterization of six cytochromes P-450 from hepatic microsomes of immature female rats. , 1987, Journal of biochemistry.

[1187] A. Makower,et al. Chemical modification of tyrosine residues at the active centre of cytochrome P-450 CAM. , 1984, Biomedica biochimica acta.

[1188] N. J. Cartwright,et al. Bacterial attack on phenolic ethers. Resolution of a Nocardia O-demethylase and purification of a cytochrome P 450 component. , 1971, Microbios.

[1189] M. J. Coon,et al. Role of a hydrophobic polypeptide in the N-terminal region of NADPH-cytochrome P-450 reductase in complex formation with P-450LM. , 1979, Biochemical and biophysical research communications.

[1190] K. Morohashi,et al. Enzymatic activities of P-450(11 beta)s expressed by two cDNAs in COS-7 cells. , 1990, Journal of biochemistry.

[1191] B. Tang,et al. Caffeine as a metabolic probe: Validation of its use for acetylator phenotyping , 1991, Clinical pharmacology and therapeutics.

[1192] I. Magnus. The cutaneous porphyrias. , 1968, Seminars in hematology.

[1193] J. Trudell,et al. Phospholipid interactions with cytochrome P-450 in reconstituted vesicles. Preference for negatively-charged phosphatidic acid. , 1981, Biochimica et biophysica acta.

[1194] O. Gotoh,et al. Xenobiotic responsive element in the 5'-upstream region of the human P-450c gene. , 1991, Journal of biochemistry.

[1195] J. Miners,et al. Normal metabolism of debrisoquine and theophylline in a slow tolbutamide metaboliser. , 1985, Australian and New Zealand journal of medicine.

[1196] M. Noshiro,et al. Unique property of liver mitochondrial P450 to catalyze the two physiologically important reactions involved in both cholesterol catabolism and vitamin D activation , 1990, FEBS letters.

[1197] M. Butler,et al. Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[1198] Y. Igarashi,et al. Importance of the unsaturated fatty acyl group of phospholipids in their stimulatory role on rat adrenal mitochondrial steroidogenesis. , 1986, Biochemistry.

[1199] A. Dahl. The Effect of Cytochrome P-450-Dependent Metabolism and Other Enzyme Activities on Olfaction , 1988 .

[1200] C. Mendelson,et al. Tissue-specific expression of human P-450AROM. The promoter responsible for expression in adipose tissue is different from that utilized in placenta. , 1991, The Journal of biological chemistry.

[1201] J. Miller,et al. The metabolism of methylated aminoazo dyes. IV. Dietary factors enhancing demethylation in vitro. , 1954, The Journal of biological chemistry.

[1202] K. Kimura,et al. Increased rate of cholic acid formation from 3α,7α-dihydroxy-5β-cholestane in perfused livers from diabetic rats , 1988 .

[1203] K. Wikvall,et al. 25-Hydroxylation of vitamin D3 by a cytochrome P-450 from rabbit liver mitochondria. , 1988, The Biochemical journal.

[1204] A. Burger,et al. Allenic cholesteryl derivatives as inhibitors of ecdysone biosynthesis , 1989 .

[1205] S. Kawato,et al. Rotation of cytochrome P-450. II. Specific interactions of cytochrome P-450 with NADPH-cytochrome P-450 reductase in phospholipid vesicles. , 1982, The Journal of biological chemistry.

[1206] P. Sinclair,et al. Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes. , 1992, Archives of biochemistry and biophysics.

[1207] R. Kato,et al. Difference in the susceptibility of two phenobarbital-inducible forms, P450IIB1 and P450IIB2, to thyroid hormone- and growth hormone-induced suppression in rat liver: phenobarbital-inducible P450IIB2 suppression by thyroid hormone acting directly, but not through the pituitary system. , 1991, Molecular pharmacology.

[1208] T. Bunse,et al. Direct effect of androgens on progesterone binding and metabolism in rat testis microsomes. , 1984, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[1209] J. Whitlock. The regulation of cytochrome P-450 gene expression. , 1986, Annual review of pharmacology and toxicology.

[1210] Topography of membrane proteins. , 1975, Biochemical Society transactions.

[1211] D. Waxman,et al. Gene conversion and differential regulation in the rat P-450 IIA gene subfamily. Purification, catalytic activity, cDNA and deduced amino acid sequence, and regulation of an adult male-specific hepatic testosterone 15 alpha-hydroxylase. , 1988, The Journal of biological chemistry.

[1212] I. Hardie,et al. Regulation of rat liver microsomal cholesterol 7α-hydroxylase by MgATP: Effect of pH , 1983 .

[1213] L. Birnbaum. Altered hepatic drug metabolism in senescent mice , 1980, Experimental Gerontology.

[1214] R. Magness,et al. Transforming growth factor-β inhibits steroid 17α-hydroxylase cytochrome P-450 expression in ovine adrenocortical cells , 1990 .

[1215] I. Wirgin,et al. Genetic polymorphism of cytochrome P-450IA in cancer-prone Hudson River tomcod , 1991 .

[1216] J. Lambeth,et al. Phospholipid vesicle-reconstituted cytochrome P-450SCC. Mutually facilitated binding of cholesterol and adrenodoxin. , 1980, The Journal of biological chemistry.

[1217] Y. Lou. Differences in drug metabolism polymorphism between Orientals and Caucasians. , 1990, Drug metabolism reviews.

[1218] A F Carne,et al. Chemical modification of proteins. , 1994, Methods in molecular biology.

[1219] F. Gonzalez,et al. The induction of a specific form of cytochrome P-450 (P-450j) by fasting. , 1987, Biochemical and biophysical research communications.

[1220] G. Vergères,et al. Localization of the N-terminal methionine of rat liver cytochrome P-450 in the lumen of the endoplasmic reticulum. , 1991, Biochimica et biophysica acta.

[1221] J. Miller,et al. The formation in vitro of protein-bound derivatives of aminoazo dyes by rat liver and its enhancement by benzypyrene pretreatment , 1958 .

[1222] H. Sasamura,et al. Effect of growth hormone on rat hepatic cytochrome P-450f mRNA: a new mode of regulation , 1990, Molecular and Cellular Endocrinology.

[1223] C. Giachelli,et al. Developmental regulation of cytochrome P-450 genes in the rat. , 1987, Molecular pharmacology.

[1224] L. Wattenberg,et al. Benzpyrene hydroxylase activity in the gastrointestinal tract. , 1962, Cancer research.

[1225] J. Lambeth,et al. Adrenodoxin interaction with adrenodoxin reductase and cytochrome P-450scc. Cross-linking of protein complexes and effects of adrenodoxin modification by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide. , 1984, The Journal of biological chemistry.

[1226] R. Skoda,et al. The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. , 1989, American journal of human genetics.

[1227] G. Dodd,et al. XENOBIOTIC METABOLISM IN THE NASAL EPITHELIUM , 1988, Drug metabolism and drug interactions.

[1228] E. A. Thompson,et al. Utilization of oxygen and reduced nicotinamide adenine dinucleotide phosphate by human placental microsomes during aromatization of androstenedione. , 1974, The Journal of biological chemistry.

[1229] D. Waxman,et al. Hormonal regulation of rat liver microsomal enzymes. Role of gonadal steroids in programming, maintenance, and suppression of delta 4-steroid 5 alpha-reductase, flavin-containing monooxygenase, and sex-specific cytochromes P-450. , 1986, The Journal of biological chemistry.

[1230] E. Schuetz,et al. Regulation of cytochrome P-450b/e and P-450p gene expression by growth hormone in adult rat hepatocytes cultured on a reconstituted basement membrane. , 1990, The Journal of biological chemistry.

[1231] J. Lancaster,et al. Participation of the membrane in the side chain cleavage of cholesterol. Reconstitution of cytochrome P-450scc into phospholipid vesicles. , 1979, The Journal of biological chemistry.

[1232] P. Strittmatter,et al. Characterization of the interaction of amphipathic cytochrome b5 with stearyl coenzyme A desaturase and NADPH:cytochrome P-450 reductase. , 1980, The Journal of biological chemistry.

[1233] H. Wynne,et al. The effect of age upon the affinity of microsomal mono-oxygenase enzymes for substrate in human liver. , 1988, Age and ageing.

[1234] U. Meyer,et al. Olfactory-specific cytochrome P-450 (P-450olf1; IIG1). Gene structure and developmental regulation. , 1990, The Journal of biological chemistry.

[1235] U. Muller-eberhard,et al. Identification of the major cytochrome P-450 form transplacentally induced in neonatal rabbits by 3,3,7,8-tetrachlorodibenzo-p-dioxin. , 1978, Journal of Biological Chemistry.

[1236] F. Bernini,et al. Regulation of low density lipoprotein metabolism by 26‐hydroxycholesterol in human fibroblasts , 1987, FEBS letters.

[1237] Kathleen R. Cho,et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. , 1990, Science.

[1238] R. ffrench-Constant,et al. Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.). , 1991, Genetical research.

[1239] W. Heller,et al. Elicitor induction of a microsomal 5-O-(4-coumaroyl)shikimate 3'-hydroxylase in parsley cell suspension cultures. , 1985, Archives of biochemistry and biophysics.

[1240] F. Guengerich,et al. In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids. , 1990, Carcinogenesis.

[1241] G. K. Ackers,et al. Effects of site-specific amino acid modification on protein interactions and biological function. , 1985, Annual review of biochemistry.

[1242] J. Whitlock,et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible, Ah receptor-mediated bending of enhancer DNA. , 1990, The Journal of biological chemistry.

[1243] S. Swartz,et al. Monoclonal antibodies to chick renal calcium regulating hemeproteins. Biochemical and immunohistochemical interactions with mitochondrial 25-hydroxyvitamin D3 hydroxylases. , 1990, Journal of clinical & laboratory immunology.

[1244] H. DeLuca,et al. Assay and properties of rat yolk sac 25-hydroxyvitamin D3 1 alpha-hydroxylase. , 1986, Biochemistry.

[1245] S. Takemori,et al. Steroidogenesis in liposomal system containing adrenal microsomal cytochrome P-450 electron transfer components. , 1989, Biochimica et biophysica acta.

[1246] P. Murphy,et al. The role of mixed function oxidases in kaurene metabolism in Echinocystis macrocarpa Greene endosperm. , 1969, Archives of biochemistry and biophysics.

[1247] G. Farrell,et al. Interferon down regulates the male-specific cytochrome P450IIIA2 in rat liver. , 1990, Molecular pharmacology.

[1248] J. Schenkman,et al. Further characterization of RLM2 and comparison with a related form of cytochrome P-450, RLM2b. , 1988, Archives of biochemistry and biophysics.

[1249] Nicholas J. Jacobs,et al. Role of inducer binding in cytochrome P-450 IA2-mediated uroporphyrinogen oxidation. , 1990, Journal of biochemical toxicology.

[1250] A. Payne. Hormonal regulation of cytochrome P450 enzymes, cholesterol side-chain cleavage and 17 alpha-hydroxylase/C17-20 lyase in Leydig cells. , 1990, Biology of reproduction.

[1251] A. Fulco,et al. Molecular cloning, coding nucleotides and the deduced amino acid sequence of P-450BM-1 from Bacillus megaterium. , 1989, Biochimica et Biophysica Acta.

[1252] J. M. Marsh,et al. Protein kinase stimulation of a reconstituted cholesterol side chain cleavage enzyme system in the bovine corpus luteum. , 1975, The Journal of biological chemistry.

[1253] S. Kubota,et al. A highly purified preparation of cytochrome P-450 from microsomes of anaerobically grown yeast. , 1977, Biochemical and biophysical research communications.

[1254] C. Walsh,et al. An aryl hydrocarbon hydroxylating hepatic cytochrome P-450 from the marine fish Stenotomus chrysops. , 1983, Archives of biochemistry and biophysics.

[1255] H. Murakami,et al. Progesterone metabolism in recombinant yeast simultaneously expressing bovine cytochromes P450c17 (CYP17A1) and P450c21 (CYP21B1) and yeast NADPH-P450 oxidoreductase. , 1991, Pharmacogenetics.

[1256] K. Mitropoulos,et al. The effect of interruption of the enterophecatic circulation of bile acids and of cholesterol feeding on cholesterol 7 alpha-hydroxylase in relation to the diurnal rhythm in its activity. , 1973, Biochimica et biophysica acta.

[1257] H. Eizawa,et al. Calmodulin-independent nitric oxide synthase from rat polymorphonuclear neutrophils. , 1991, The Journal of biological chemistry.

[1258] J. Saunders,et al. Localization of Cinnamic Acid 4-Monooxygenase and the Membrane-bound Enzyme System for Dhurrin Biosynthesis in Sorghum Seedlings. , 1977, Plant physiology.

[1259] E. J. Norman,et al. Synthesis of 1,25-dihydroxyvitamin D3 by human placenta in vitro. , 1981, The Journal of clinical endocrinology and metabolism.

[1260] O. Sugita,et al. Drug metabolism by the human hepatoma cell, Hep G2. , 1987, Biochemical and biophysical research communications.

[1261] R. Branch,et al. Mephenytoin hydroxylation deficiency: Kinetics after repeated doses , 1984, Clinical pharmacology and therapeutics.

[1262] J. Lambeth,et al. Cytochrome P-450scc-adrenodoxin interactions. Ionic effects on binding, and regulation of cytochrome reduction by bound steroid substrates. , 1985, The Journal of biological chemistry.

[1263] G. Farrell,et al. Increased expression of cytochrome P450 IIIA2 in male rat liver after dietary vitamin A supplementation. , 1991, Archives of biochemistry and biophysics.

[1264] D. Nebert,et al. Human P3(450): cDNA and complete amino acid sequence. , 1986, Nucleic acids research.

[1265] A Ellinger,et al. Isolation of two developmentally regulated genes involved in spore wall maturation in Saccharomyces cerevisiae. , 1990, Genes & development.

[1266] Dr. Peter F. Hall,et al. Cytochromes P-450 and the regulation of steroid synthesis , 1986, Steroids.

[1267] T. E. Gram. Extrahepatic metabolism of drugs and other foreign compounds , 1980 .

[1268] D. Johnson. Loss of ovarian 17 alpha-hydroxylase/C17,20-lyase activity induced by human chorionic gonadotropin is correlated with in vivo substrate availability. , 1988, Journal of steroid biochemistry.

[1269] S. Shefer,et al. Inborn errors of bile acid synthesis. , 1977, Clinics in gastroenterology.

[1270] J. Garancis,et al. Evidence that stimulation of 1,25(OH)2D3 production in primary cultures of mouse kidney cells by cyclic AMP requires new protein synthesis , 1987, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[1271] E. Bresnick,et al. Correlation of induction of aryl hydrocarbon hydroxylase in cultured rat hepatocytes with saturable high-affinity binding of 3-methylcholanthrene to a 4S cytoplasmic protein. , 1981, Cancer research.

[1272] H. Strobel,et al. Effects of cyclophosphamide and polycyclic aromatic hydrocarbons on cell growth and mixed-function oxidase activity in a human colon tumor cell line. , 1982, Cancer research.

[1273] E. Jeffery. Human Drug Metabolism: From Molecular Biology to Man , 1992 .

[1274] K. Iwahashi,et al. Catalytic properties of cytochrome P-450scc from bovine and porcine adrenocortical mitochondria: Effect of tween20 concentration , 1991, The Journal of Steroid Biochemistry and Molecular Biology.

[1275] J. Felton,et al. Expression of mouse cytochrome P4501A1 cDNA in repair‐deficient and repair‐proficient CHO cells , 1991, Molecular carcinogenesis.

[1276] J. Salaün,et al. omega-Hydroxylation of Z9-octadecenoic, Z9,10-epoxystearic and 9,10-dihydroxystearic acids by microsomal cytochrome P450 systems from Vicia sativa. , 1992, Biochemical and biophysical research communications.

[1277] H. Murakami,et al. Expression of cloned yeast NADPH-cytochrome P450 reductase gene in Saccharomyces cerevisiae. , 1990, Journal of biochemistry.

[1278] E. Morgan,et al. Regulation of cytochrome P450IIC12 expression by interleukin-1 alpha, interleukin-6, and dexamethasone. , 1991, Molecular pharmacology.

[1279] R. Mulligan,et al. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[1280] R. Sexton,et al. Modulation of regulatory oxysterol formation and low density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by ketoconazole. A role for cytochrome P-450 in the regulation of HMG-CoA reductase in rat intestinal epithelial cells. , 1986, The Journal of biological chemistry.

[1281] C. Woodworth,et al. Maintenance of differentiated rat hepatocytes in primary culture. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[1282] R. Estabrook,et al. On the inhibitory action of mersalyl on microsomal drug oxidation: a rigid organization of the electron transport chain. , 1971, Archives of biochemistry and biophysics.

[1283] P. White. Genetics of steroid 21-hydroxylase deficiency. , 1987, Recent progress in hormone research.

[1284] A. Llerena,et al. Polymorphic oxidation of debrisoquine in lung cancer patients. , 1991, European journal of cancer.

[1285] J. Hevel,et al. Macrophage nitric oxide synthase: relationship between enzyme-bound tetrahydrobiopterin and synthase activity. , 1992, Biochemistry.

[1286] T. Shimada,et al. Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. , 1989, Cancer research.

[1287] J. Seidman,et al. An enhancer element and a functional cyclic AMP-dependent protein kinase are required for expression of adrenocortical 21-hydroxylase. , 1988, The Journal of biological chemistry.

[1288] A. Rösler,et al. High frequency of congenital adrenal hyperplasia (classic 11 beta-hydroxylase deficiency) among Jews from Morocco. , 1992, American journal of medical genetics.

[1289] S. Jacob,et al. Role of RNA in induction of hepatic microsomal mixed function oxidases. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[1290] J. Lambeth,et al. Cytochrome P-450scc-phospholipid interactions. Evidence for a cardiolipin binding site and thermodynamics of enzyme interactions with cardiolipin, cholesterol, and adrenodoxin. , 1983, The Journal of biological chemistry.

[1291] R. Krishnamoorthy,et al. Distinct phenotypes and genotypes of debrisoquine hydroxylation among Europeans and Chinese. , 1991, British journal of clinical pharmacology.

[1292] S. Sligar,et al. Purification and Characterization of Microsomal Cytochrome b(5) and NADH Cytochrome b(5) Reductase from Pisum sativum. , 1987, Plant physiology.

[1293] F. Gonzalez,et al. Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family. , 1987, The Journal of biological chemistry.

[1294] J. Masferrer,et al. 12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium. , 1988, The Journal of biological chemistry.

[1295] S. Kawato,et al. Protein rotation study of cytochrome P-450 in submitochondrial particles: effect of KCl and intermolecular interactions with redox partners. , 1991, Journal of biochemistry.

[1296] M. Marletta,et al. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. , 1988, Biochemistry.

[1297] A. Fulco,et al. A barbiturate-regulated protein binding to a common sequence in the cytochrome P450 genes of rodents and bacteria. , 1991, The Journal of biological chemistry.

[1298] G. Siest,et al. Brain mitochondrial cytochrome P-450scc: spectral and catalytic properties. , 1987, Archives of biochemistry and biophysics.

[1299] P. Hall,et al. Microsomal cytochrome P-450 from neonatal pig testis. Purification and properties of A C21 steroid side-chain cleavage system (17 alpha-hydroxylase-C17,20 lyase). , 1981, The Journal of biological chemistry.

[1300] T. Omura,et al. Different requirement for cytochrome b5 in NADPH-supported O-deethylation of p-nitrophenetole catalyzed by two types of microsomal cytochrome P-450. , 1980, Biochemical and biophysical research communications.

[1301] R. Kato,et al. Enhancement by alloxan-induced diabetes of the rate of metabolic activation of three pyrolysate carcinogens via increase in the P-448-H content in rat liver. , 1988, Biochemical pharmacology.

[1302] R. Kato,et al. Regulations of male-dominant P-450Md mRNA in rat liver by hormonal factors and xenobiotics. , 1991, Japanese journal of pharmacology.

[1303] G. Gordon,et al. Conversion of androgens to estrogens in cirrhosis of the liver. , 1975, The Journal of clinical endocrinology and metabolism.

[1304] H. Buttar,et al. Propranolol metabolism by Cunninghamella bainieri. , 1989, Xenobiotica; the fate of foreign compounds in biological systems.

[1305] C. Chengelis. Age- and sex-related changes in the components of the hepatic microsomal mixed function oxidase system in Sprague-Dawley rats. , 1988, Xenobiotica; the fate of foreign compounds in biological systems.

[1306] F. Durst,et al. Xenobiotic metabolism in plants: Aryl hydroxylation of diclofop by a cytochrome P-450 enzyme from wheat , 1990 .

[1307] A. Stier,et al. The site of cyclic AMP‐dependent protein kinase catalyzed phosphorylation of cytochrome P‐450 LM2 , 1985, FEBS letters.

[1308] F. Gonzalez,et al. cDNA and amino acid sequences of two members of the human P450IIC gene subfamily. , 1987, Nucleic acids research.

[1309] P. Thomas,et al. Evidence for a family of four immunochemically related isozymes of cytochrome P-450 purified from untreated rats. , 1985, Archives of biochemistry and biophysics.

[1310] S. Usanov,et al. [Localization of tetranitromethane-modified tyrosine residues in the polypeptide chain of cholesterol-hydroxylating cytochrome P-450]. , 1987, Bioorganicheskaia khimiia.

[1311] J. Bergé,et al. Characterization of microsomal oxidative activities in a wild-type and in a DDT resistant strain of , 1990 .

[1312] J. A. Romesser,et al. Plant and Bacterial Cytochromes P-450: Involvement in Herbicide Metabolism , 1987 .

[1313] W. P. Norred,et al. Dietary fatty acid-induced alterations of hepatic microsomal drug metabolism. , 1972, Biochemical pharmacology.

[1314] L. Geren,et al. Identification of specific carboxylate groups on adrenodoxin that are involved in the interaction with adrenodoxin reductase. , 1984, The Journal of biological chemistry.

[1315] C. S. Vaidyanathan,et al. Metabolism of monoterpene alcohol, linalool, by a soil pseudomonad. , 1977, Canadian journal of microbiology.

[1316] J. Fishman,et al. 2-Hydroxylation of estrogens in the brain participates in the initiation of the preovulatory LH surge in the rat. , 1980, Biochemical and biophysical research communications.

[1317] D. Nebert,et al. Evolution of the P450 gene superfamily. , 1988, Progress in clinical and biological research.

[1318] L. Birnbaum,et al. Induction of hepatic mixed function oxidases in senescent rodents , 1978, Experimental Gerontology.

[1319] A. Fulco,et al. Cloning of the gene encoding a catalytically self-sufficient cytochrome P-450 fatty acid monooxygenase induced by barbiturates in Bacillus megaterium and its functional expression and regulation in heterologous (Escherichia coli) and homologous (Bacillus megaterium) hosts. , 1987, The Journal of biological chemistry.

[1320] E. Chambaz,et al. Phosphorylation of bovine adrenodoxin. Structural study and enzymatic activity. , 1987, European journal of biochemistry.

[1321] T. Kronbach,et al. Cyclosporine metabolism in human liver: Identification of a cytochrome P‐450III gene family as the major cyclosporine‐metabolizing enzyme explains interactions of cyclosporine with other drugs , 1988, Clinical pharmacology and therapeutics.

[1322] G. Jänig,et al. Identification of the ligand trans to thiolate in cytochrome P‐450 LM2 by chemical modification , 1983, FEBS letters.

[1323] J. Williams,et al. Induction of sister chromatid exchanges in human and rat hepatoma cell lines by cyclophosphamide and phosphoramide mustard and the effects of cytochrome P-450 inhibitors. , 1986, Biochemical pharmacology.

[1324] K. Ruckpattl,et al. Chapter 1 Biochemical Aspects of the Monooxygenase System in the Endoplasmic Reticulum of Mammalian Liver , 1984, Cytochrome P-450.

[1325] J. Idle,et al. Comparison of a novel thin-layer chromatographic-fluorescence detection method with a spectrofluorometric method for the determination of 7-hydroxycoumarin in human urine. , 1992, Journal of chromatography.

[1326] C. Omiecinski. Tissue-specific expression of rat mRNAs homologous to cytochromes P-450b and P-450e. , 1986, Nucleic acids research.

[1327] H. Müller,et al. Isolierung und Rekonstitution des Alkan-Monooxygenase-Systems der Hefe Lodderomyces elongisporus , 1983, 1983.

[1328] C. Wolf,et al. The rabbit pulmonary monooxygenase system. Immunochemical and biochemical characterization of enzyme components. , 1979, The Journal of biological chemistry.

[1329] K. Leto,et al. Cytochrome P-450 from the Mesocarp of Avocado (Persea americana). , 1989, Plant physiology.

[1330] K. Nakachi,et al. Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P45 0IA1 gene , 1990, FEBS letters.

[1331] G. Hook,et al. A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit. , 1972, The Journal of pharmacology and experimental therapeutics.

[1332] T. Kamataki,et al. Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450. , 1989, Journal of biochemistry.

[1333] A. Ito,et al. Critical region in the extension peptide for the import of cytochrome P-450(SCC) precursor into mitochondria. , 1989, Journal of biochemistry.

[1334] M. Rubenfield,et al. Sex and strain differences in hepatic debrisoquine 4-hydroxylase activity of the rat. , 1985, Drug metabolism and disposition: the biological fate of chemicals.

[1335] G. L. Youngblood,et al. The structural genes encoding P450scc and P450arom are closely linked on mouse chromosome 9. , 1989, Endocrinology.

[1336] Y. Yokoyama,et al. Alternative usage of different poly(A) addition signals for two major species of mRNA encoding human aromatase P‐450 , 1989, FEBS letters.

[1337] K. Pommerening,et al. Modification of carboxyl groups on NADPH-cytochrome P-450 reductase involved in binding of cytochromes c and P-450 LM2. , 1987, Biochemistry international.

[1338] P. Quinn. Membrane lipid phase behaviour and lipid-protein interactions. , 1990, Biochemical Society transactions.

[1339] A. Paine,et al. The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system. , 1990, Chemico-biological interactions.

[1340] C. Hahn,et al. Transcriptional regulation of the chicken CYP2H1 gene. Localization of a phenobarbital-responsive enhancer domain. , 1991, The Journal of biological chemistry.

[1341] J. Moore,et al. Investigation of an S-adenosylmethionine: delta 24-sterol methyltransferase in ergosterol biosynthesis in yeast. Specificity of sterol substrates and inhibitors. , 1970, The Journal of biological chemistry.

[1342] A. Herzog,et al. Acute effects of anticonvulsant drugs on gonadotropin-stimulated and precursor-supported androgen production in the rat testis. , 1990, European journal of pharmacology.

[1343] M. J. Coon,et al. Purification and characterization of two unique forms of cytochrome P-450 from rabbit nasal microsomes. , 1988, Biochemistry.

[1344] R. Turner,et al. Regulation of 25-hydroxyvitamin D3 metabolism in chick embryo. , 1987, The American journal of physiology.

[1345] Yoshiyuki Tanaka,et al. Properties, development and cellular-localization of cinnamic acid 4-hydroxylase in cut-injured sweet potato , 1974 .

[1346] P. Cole,et al. Peroxide model reaction for placental aromatase , 1988 .

[1347] E. Lodola. [Pharmacokinetics in the old age]. , 1973, Bollettino chimico farmaceutico.

[1348] M. Haniu,et al. Amino acid sequence of the Pseudomonas putida cytochrome P-450. II. Cyanogen bromide peptides, acid cleavage peptides, and the complete sequence. , 1982, The Journal of biological chemistry.

[1349] W. Levin,et al. Purification and characterization of hepatic microsomal cytochrome P-450. , 1990, Pharmacology & therapeutics.

[1350] J. Darnell,et al. Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes , 1983, Molecular and cellular biology.