Circular Dichroism and Conformation of Bilirubin Bis N, N, N-Trimethyl α-Phenethylammonium Salts

Abstract Analysis of the bisignate circular dichroism spectra of bilirubin-IXα bis-propionate salts of (S)-(-)-N, N, N-trimethyl α-phenethylammonium hydroxide reveals a preference in CHC13, (CH3)2 CO and CH3 CN solvents for folded conformations in which the propionate groups are intramolecularly H-bonded to the opposing pyrromethenone units.

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