Self-Reported Alcohol, Tobacco, and Marijuana Use in Pregnant Women with Depressive Symptomatology

Abstract Objective Substance use disorders often coexist with depression. The objective of this study was to establish whether pregnant women who report depressive symptomatology were more likely to report use of alcohol, tobacco, and marijuana during pregnancy. Study Design This was a secondary analysis of prospectively collected data from the Maternal-Fetal Medicine Units Network Preterm Prediction Study. Self-reported history of alcohol, tobacco, and marijuana use was compared between pregnant women with and without depressive symptomatology with adjustment for demographic factors. Results After adjustment for demographic factors, women with depressive symptomatology were more likely to report: any alcohol use (odds ratio [OR]: 1.4, 95% confidence interval [CI]: 1.1–1.8), >1 drink per week (OR: 1.3, 95% CI: 1.0–1.8), and >1 drink per day (OR: 2.2, 95% CI: 1.5–3.4). Women with depressive symptomatology were also more likely to report use of marijuana (OR: 1.8, 95% CI: 1.2–2.6) and cigarettes (OR: 1.4, 95% CI: 1.1–1.7). Conclusion Depressive symptomatology was associated with an increase in self-reported the use of alcohol, tobacco, and marijuana during pregnancy. These data reveal the importance of targeted screening of pregnant women with depressive symptomatology for substance use.

[1]  Jennifer A. Pellowski,et al.  The National Institute on Alcohol Abuse and Alcoholism , 1995, Alcohol health and research world.

[2]  Christopher P. Salas-Wright,et al.  Marijuana use during pregnancy: A comparison of trends and correlates among married and unmarried pregnant women. , 2017, Drug and alcohol dependence.

[3]  S. Galea,et al.  Smoking during pregnancy in the United States, 2005-2014: The role of depression. , 2017, Drug and alcohol dependence.

[4]  Steve Allsop,et al.  Prenatal Alcohol Consumption Between Conception and Recognition of Pregnancy , 2017, Alcoholism, clinical and experimental research.

[5]  Denise V. D’Angelo,et al.  Smoking Before and During Pregnancy Among Women Reporting Depression or Anxiety , 2016, Obstetrics and gynecology.

[6]  Committee Opinion No. 633: Alcohol Abuse and Other Substance Use Disorders Ethical Issues in Obstetric and Gynecologic Practice , 2015, Obstetrics and gynecology.

[7]  Y. Nikitin,et al.  Drinking Pattern, Abstention and Problem Drinking as Risk Factors for Depressive Symptoms: Evidence from Three Urban Eastern European Populations , 2014, PloS one.

[8]  C. Parker,et al.  Association Between Stillbirth and Illicit Drug Use and Smoking During Pregnancy , 2014, Obstetrics and gynecology.

[9]  K. Wolff,et al.  Screening for substance abuse in women's health: a public health imperative. , 2013, Journal of midwifery & women's health.

[10]  Bethany J Figg,et al.  National Institute of Child Health and Human Development , 2013 .

[11]  C. Dennis,et al.  Psychosocial and psychological interventions for preventing postpartum depression. , 2013, The Cochrane database of systematic reviews.

[12]  D. Fergusson,et al.  Alcohol and depression. , 2011, Addiction.

[13]  C. Cooper,et al.  Do women change their health behaviours in pregnancy? Findings from the Southampton Women's Survey. , 2009, Paediatric and perinatal epidemiology.

[14]  T. Brugha,et al.  The Leicester 500 Project. Social support and the development of postnatal depressive symptoms, a prospective cohort survey , 1998, Psychological Medicine.

[15]  A. Meier,et al.  The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks' gestation. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. , 1996, American journal of obstetrics and gynecology.

[16]  L. Appleby,et al.  Demographic and Obstetric Risk Factors for Postnatal Psychiatric Morbidity , 1996, British Journal of Psychiatry.

[17]  B. Grant,et al.  Comorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey. , 1995, Drug and alcohol dependence.

[18]  P. Kielholz.  Alcohol and depression. , 1970, The British journal of addiction to alcohol and other drugs.

[19]  Committee opinion no. 496: At-risk drinking and alcohol dependence: obstetric and gynecologic implications. , 2011, Obstetrics and gynecology.

[20]  M. Dufour,et al.  The motivational correlates of drinking, smoking, and illicit drug use during pregnancy. , 1994, Journal of substance abuse.