Computer Electronics Meet Animal Brains

Although digital computers and nerve tissue both use voltage waveforms to transmit and process information, engineers and neurobiologists have yet to cohesively link the electronic signaling of digital computers with the electronic signaling of nerve tissue in freely behaving animals. Recent advances will finally let us link computer circuitry to neural cells in live animals and, in particular, to reidentifiable cells with specific, known neural functions. By enabling neuroscientists to better understand the neural basis of behavior, these devices may someday lead to neural prosthetics, hardware-based human-computer interfaces, and artificial systems that incorporate principles of biological intelligence.

[1]  D. D. Denton,et al.  Micromachining of non-fouling coatings for bio-MEMS applications , 2001 .

[2]  J. Bates Thin-Film Lithium and Lithium-Ion Batteries , 2000 .

[3]  Russell C. Wyeth,et al.  Towards MEMS Probes for Intracellular Recording , 2002 .

[4]  M. D. Gingerich,et al.  Use of an active microelectrode array for stimulation and recording in the central nervous system , 1999, Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. N.