Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.
暂无分享,去创建一个
[1] Steven P Jones,et al. Cardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxia. , 2008, American journal of physiology. Heart and circulatory physiology.
[2] L. Huang,et al. Carrot and stick: HIF-α engages c-Myc in hypoxic adaptation , 2008, Cell Death and Differentiation.
[3] R. Bartrons,et al. Characterization of a new liver- and kidney-specific pfkfb3 isozyme that is downregulated by cell proliferation and dedifferentiation. , 2008, Biochemical and Biophysical Research Communications - BBRC.
[4] John O Trent,et al. Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth , 2008, Molecular Cancer Therapeutics.
[5] Jaime Caro,et al. Hypoxia, glucose metabolism and the Warburg’s effect , 2007, Journal of bioenergetics and biomembranes.
[6] Emma Saavedra,et al. Energy metabolism in tumor cells , 2007, The FEBS journal.
[7] A. Lane,et al. Ras transformation requires metabolic control by 6-phosphofructo-2-kinase , 2006, Oncogene.
[8] Chi V Dang,et al. Cancer's molecular sweet tooth and the Warburg effect. , 2006, Cancer research.
[9] H. Pelicano,et al. Glycolysis inhibition for anticancer treatment , 2006, Oncogene.
[10] Eyal Gottlieb,et al. TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis , 2006, Cell.
[11] R. Bartrons,et al. PFKFB3 gene silencing decreases glycolysis, induces cell‐cycle delay and inhibits anchorage‐independent growth in HeLa cells , 2006, FEBS letters.
[12] M. López-Lázaro. HIF‐1: hypoxia‐inducible factor or dysoxia‐inducible factor? , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[13] D. Rigden,et al. Evolutionary analysis of fructose 2,6‐bisphosphate metabolism , 2006, IUBMB life.
[14] Yong-Hwan Lee,et al. Crystal Structure of the Hypoxia-inducible Form of 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) , 2006, Journal of Biological Chemistry.
[15] B. Sharma,et al. PET/CT in oncology--a major advance. , 2005, Clinical radiology.
[16] Marta Cascante,et al. K-ras Codon-Specific Mutations Produce Distinctive Metabolic Phenotypes in Human Fibroblasts , 2005 .
[17] A. Yalçin,et al. Targeted disruption of inducible 6-phosphofructo-2-kinase results in embryonic lethality. , 2005, Biochemical and biophysical research communications.
[18] S. Schreiber,et al. Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[19] R. Gillies,et al. Hypoxia-Inducible Factor-1α and the Glycolytic Phenotype in Tumors , 2005 .
[20] N. Amariglio,et al. Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. , 2005, Cancer research.
[21] Peng Huang,et al. Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. , 2005, Cancer research.
[22] David Beach,et al. Glycolytic enzymes can modulate cellular life span. , 2005, Cancer research.
[23] R. Gillies,et al. Why do cancers have high aerobic glycolysis? , 2004, Nature Reviews Cancer.
[24] D. Vertommen,et al. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis. , 2004, The Biochemical journal.
[25] P. Hammerman,et al. Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[26] J. Caro,et al. Hypoxic regulation of the 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase gene family (PFKFB‐1–4) expression in vivo , 2003, FEBS letters.
[27] G. Semenza. Targeting HIF-1 for cancer therapy , 2003, Nature Reviews Cancer.
[28] J. L. Rosa,et al. Regulation of ubiquitous 6‐phosphofructo‐2‐kinase by the ubiquitin‐proteasome proteolytic pathway during myogenic C2C12 cell differentiation , 2003, FEBS letters.
[29] L. Leng,et al. High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers. , 2002, Cancer research.
[30] L. Bertrand,et al. Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways. , 2002, Journal of molecular and cellular cardiology.
[31] L. Bertrand,et al. The Stimulation of Glycolysis by Hypoxia in Activated Monocytes Is Mediated by AMP-activated Protein Kinase and Inducible 6-Phosphofructo-2-kinase* , 2002, The Journal of Biological Chemistry.
[32] R. Bartrons,et al. Insulin induces PFKFB3 gene expression in HT29 human colon adenocarcinoma cells. , 2002, Biochimica et biophysica acta.
[33] N. Sang,et al. Hypoxia-inducible Factor-1-mediated Expression of the 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) Gene , 2002, The Journal of Biological Chemistry.
[34] W. Zwerschke,et al. Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7 , 2001, Oncogene.
[35] M Cascante,et al. Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells. , 2001, The Journal of biological chemistry.
[36] T. Hunter,et al. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. , 2001, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[37] K. Eschrich,et al. Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain. , 2001, Brain research. Molecular brain research.
[38] J. L. Rosa,et al. The human ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3): promoter characterization and genomic structure. , 2001, Gene.
[39] L. Boros,et al. Genistein Inhibits Nonoxidative Ribose Synthesis in MIA Pancreatic Adenocarcinoma Cells: A New Mechanism of Controlling Tumor Growth , 2001, Pancreas.
[40] C. Dang,et al. Deregulation of Glucose Transporter 1 and Glycolytic Gene Expression by c-Myc* , 2000, The Journal of Biological Chemistry.
[41] M. Cascante,et al. Transforming growth factor beta2 promotes glucose carbon incorporation into nucleic acid ribose through the nonoxidative pentose cycle in lung epithelial carcinoma cells. , 2000, Cancer research.
[42] D A Hilton,et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. , 1999, Cancer research.
[43] E. Furuya,et al. Tissue‐specific alternative splicing of rat brain fructose 6‐phosphate 2‐kinase/fructose 2,6‐bisphosphatase , 1999, FEBS letters.
[44] C. Paraskeva,et al. An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: implications for clonal selection during colorectal carcinogenesis , 1999, Oncogene.
[45] R. Sakakibara,et al. Tissue distribution of placenta-type 6-phosphofructo- 2-kinase/fructose-2,6-bisphosphatase. , 1999, Biochemical and biophysical research communications.
[46] R. Bucala,et al. An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[47] X. Estivill,et al. Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase gene (PFKFB3) , 1999, Cytogenetic and Genome Research.
[48] C. Dang,et al. A unique glucose-dependent apoptotic pathway induced by c-Myc. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[49] R. Sakakibara,et al. Characterization of a human placental fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase. , 1997, Journal of biochemistry.
[50] Akiko Sakai,et al. Novel Isoforms of Rat Brain Fructose 6‐Phosphate 2‐Kinase/Fructose 2,6‐Bisphosphatase Are Generated by Tissue‐Specific Alternative Splicing , 1997, Journal of neurochemistry.
[51] C. Sánchez-Martínez,et al. Analysis of phosphofructokinase subunits and isozymes in ascites tumor cells and its original tissue, murine mammary gland , 1997, FEBS letters.
[52] J. A. Hamilton,et al. Identification of PRG1, a novel progestin-responsive gene with sequence homology to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. , 1997, Molecular endocrinology.
[53] R. Sakakibara,et al. Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta. , 1996, Journal of biochemistry.
[54] L. Hue,et al. Activation of 6-phosphofructo-2-kinase by pp60v-src is an indirect effect. , 1992, The Biochemical journal.
[55] H. Kole,et al. Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts. , 1991, Archives of biochemistry and biophysics.
[56] Joyce Bos. ras oncogenes in human cancer: a review. , 1989, Cancer research.
[57] C. V. van Veelen,et al. Subunit composition, regulatory properties, and phosphorylation of phosphofructokinase from human gliomas. , 1987, Cancer research.
[58] D. Colomer,et al. Control of phosphofructokinase by fructose 2,6-bisphosphate in B-lymphocytes and B-chronic lymphocytic leukemia cells. , 1987, Cancer research.
[59] J. Ghysdael,et al. Expression of the v-src or v-fps oncogene increases fructose 2,6-bisphosphate in chick-embryo fibroblasts. Novel mechanism for the stimulation of glycolysis by retroviruses. , 1986, The Biochemical journal.
[60] D. Knowles,et al. Alterations in the activity and isozymic profile of human phosphofructokinase during malignant transformation in vivo and in vitro: transformation- and progression-linked discriminants of malignancy. , 1985, Cancer research.
[61] H. Hers. The discovery and the biological role of fructose 2,6-bisphosphate. , 1984, Biochemical Society transactions.
[62] E. Schaftingen,et al. Fructose 2,6-bisphosphate. , 1982, Biochemical Society Transactions.
[63] E. Schaftingen,et al. Control of liver 6-phosphofructokinase by fructose 2,6-bisphosphate and other effectors. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[64] E. Schaftingen,et al. Fructose 2,6-bisphosphate, the probably structure of the glucose- and glucagon-sensitive stimulator of phosphofructokinase. , 1980, The Biochemical journal.
[65] E. Schaftingen,et al. Control of the fructose-6-phosphate/fructose 1,6-bisphosphate cycle in isolated hepatocytes by glucose and glucagon. Role of a low-molecular-weight stimulator of phosphofructokinase. , 1980, The Biochemical journal.
[66] D. Goldberg,et al. Enzymes of glucose metabolism in carcinoma of the cervix and endometrium of the human uterus. , 1978, British Journal of Cancer.
[67] G. Weber. Enzymology of cancer cells (second of two parts). , 1977, The New England journal of medicine.
[68] Chi V. Dang,et al. The interplay between MYC and HIF in cancer , 2008, Nature Reviews Cancer.
[69] R. Deberardinis,et al. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. , 2008, Cell metabolism.
[70] S. Khan,et al. Roles for fructose-2,6-bisphosphate in the control of fuel metabolism: beyond its allosteric effects on glycolytic and gluconeogenic enzymes. , 2006, Advances in enzyme regulation.
[71] Chaodong Wu,et al. Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. , 2004, Advances in enzyme regulation.
[72] R. Bartrons,et al. PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate. , 2001, Trends in biochemical sciences.
[73] Z. Ronai,et al. K-ras mutation: early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers--a review. , 2000, Cancer detection and prevention.
[74] A. Lange,et al. Fructose‐2,6‐bisphosphate and control of carbohydrate metabolism in eukaryotes , 1999, BioFactors.
[75] L. Hue,et al. Fructose 2,6-bisphosphate and the control of glycolysis by growth factors, tumor promoters and oncogenes. , 1993, Advances in enzyme regulation.
[76] S. Mango,et al. cis-acting determinants of c-myc mRNA stability. , 1990, Enzyme.
[77] B. V. van Oirschot,et al. Glycolytic enzyme activities in breast cancer metastases. , 1988, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
[78] B. V. van Oirschot,et al. Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue. , 1987, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.