Translocation of positively and negatively charged polystyrene nanoparticles in an in vitro placental model.

[1]  A. Marcelis,et al.  Cytotoxicity of surface-functionalized silicon and germanium nanoparticles: the dominant role of surface charges. , 2013, Nanoscale.

[2]  L. Knudsen,et al.  Modelling of human transplacental transport as performed in Copenhagen, Denmark. , 2014, Basic & clinical pharmacology & toxicology.

[3]  K. Audus,et al.  Functional expression of P-glycoprotein in primary cultures of human cytotrophoblasts and BeWo cells. , 2000, Reproductive toxicology.

[4]  C. Sibley,et al.  Role of MDR1 and MRP1 in trophoblast cells, elucidated using retroviral gene transfer. , 2003, American journal of physiology. Cell physiology.

[5]  D. Barron,et al.  Metabolism and Transport of the Citrus Flavonoid Hesperetin in Caco-2 Cell Monolayers , 2008, Drug Metabolism and Disposition.

[6]  Adela C. Bonoiu,et al.  Hyperbranched polysiloxysilane nanoparticles: surface charge control of nonviral gene delivery vectors and nanoprobes. , 2009, International journal of pharmaceutics.

[7]  Mélanie Auffan,et al.  Protein corona formation for nanomaterials and proteins of a similar size: hard or soft corona? , 2013, Nanoscale.

[8]  G. Lowry,et al.  Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective. , 2009, Nature nanotechnology.

[9]  L. Knudsen,et al.  Modeling placental transport: correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion. , 2009, Toxicology in vitro : an international journal published in association with BIBRA.

[10]  Hyun-Jong Cho,et al.  Poly(styrene)-b-poly(DL-lactide) copolymer-based nanoparticles for anticancer drug delivery , 2014, International journal of nanomedicine.

[11]  Gilbert Bensimon,et al.  Interactions between riluzole and ABCG2/BCRP transporter , 2009, Neuroscience Letters.

[12]  Jian Ji,et al.  Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells. , 2013, Langmuir : the ACS journal of surfaces and colloids.

[13]  Peter Wick,et al.  Determination of the transport rate of xenobiotics and nanomaterials across the placenta using the ex vivo human placental perfusion model. , 2013, Journal of visualized experiments : JoVE.

[14]  P. Myllynen,et al.  Kinetics of gold nanoparticles in the human placenta. , 2008, Reproductive toxicology.

[15]  Iseult Lynch,et al.  Serum heat inactivation affects protein corona composition and nanoparticle uptake. , 2010, Biomaterials.

[16]  Gottfried Dohr,et al.  Nanomaterial interference with early human placenta: Sophisticated matter meets sophisticated tissues. , 2013, Reproductive toxicology.

[17]  Margaret Saunders,et al.  Transplacental transport of nanomaterials. , 2009, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[18]  E. Oberdörster.  Manufactured Nanomaterials (Fullerenes, C60) Induce Oxidative Stress in the Brain of Juvenile Largemouth Bass , 2004, Environmental health perspectives.

[19]  P. Pávek,et al.  EXPRESSION AND FUNCTIONAL ACTIVITY OF BREAST CANCER RESISTANCE PROTEIN (BCRP, ABCG2) TRANSPORTER IN THE HUMAN CHORIOCARCINOMA CELL LINE BEWO , 2006, Clinical and experimental pharmacology & physiology.

[20]  Claudia J. Bode,et al.  In vitro models for studying trophoblast transcellular transport. , 2006, Methods in molecular medicine.

[21]  Reinhard Niessner,et al.  Langendorff heart: a model system to study cardiovascular effects of engineered nanoparticles. , 2011, ACS nano.

[22]  G. Oberdörster,et al.  Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles , 2005, Environmental health perspectives.

[23]  J. Leng,et al.  [Transplacental transfer of 5 antibiotics by in vitro human placental perfusion]. , 1985, Pathologie-biologie.

[24]  Peter Wick,et al.  Barrier Capacity of Human Placenta for Nanosized Materials , 2009, Environmental health perspectives.

[25]  B. van Ravenzwaay,et al.  Assessment of an in vitro transport model using BeWo b30 cells to predict placental transfer of compounds , 2013, Archives of Toxicology.

[26]  J. Keelan,et al.  ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast. , 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

[27]  K. Audus,et al.  MRP isoforms and BCRP mediate sulfate conjugate efflux out of BeWo cells. , 2010, International journal of pharmaceutics.

[28]  M. Saunders,et al.  The toxicity, transport and uptake of nanoparticles in the in vitro BeWo b30 placental cell barrier model used within NanoTEST , 2015, Nanotoxicology.

[29]  K. Audus,et al.  The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line. , 2003, Placenta.

[30]  P. Artursson,et al.  Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. , 1991, Biochemical and biophysical research communications.

[31]  Hazem Ali,et al.  Preparation, characterization, and transport of dexamethasone-loaded polymeric nanoparticles across a human placental in vitro model. , 2013, International journal of pharmaceutics.

[32]  Vincent Castranova,et al.  Surface area of particle administered versus mass in determining the pulmonary toxicity of ultrafine and fine carbon black: comparison to ultrafine titanium dioxide , 2009, Particle and Fibre Toxicology.

[33]  A. Arora,et al.  Review: nanocomposites in food packaging. , 2010, Journal of food science.

[34]  Cytotoxicity and cellular uptake of tri-block copolymer nanoparticles with different size and surface characteristics , 2012, Particle and Fibre Toxicology.

[35]  R. Kannan,et al.  Transfer of PAMAM dendrimers across human placenta: prospects of its use as drug carrier during pregnancy. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[36]  A. Marcelis,et al.  Surface charge-specific cytotoxicity and cellular uptake of tri-block copolymer nanoparticles , 2013, Nanotoxicology.

[37]  H. Bouwmeester,et al.  Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity , 2015, Nanotoxicology.

[38]  H. M. Nielsen,et al.  In vitro placental model optimization for nanoparticle transport studies , 2012, International journal of nanomedicine.

[39]  G. Dohr,et al.  Studying nanoparticle interaction with human placenta: Festina lente! , 2015, Nanotoxicology.

[40]  L. Knudsen,et al.  Kinetics of silica nanoparticles in the human placenta , 2015, Nanotoxicology.

[41]  H Nakano,et al.  Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein. , 2000, European journal of pharmacology.

[42]  T. Xia,et al.  Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress. , 2015, Nanoscale.

[43]  Kenneth A. Dawson,et al.  Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts , 2008, Proceedings of the National Academy of Sciences.

[44]  K. Dawson,et al.  Effects of Transport Inhibitors on the Cellular Uptake of Carboxylated Polystyrene Nanoparticles in Different Cell Lines , 2011, PloS one.

[45]  P. Wick,et al.  Knocking at the door of the unborn child: engineered nanoparticles at the human placental barrier. , 2012, Swiss medical weekly.

[46]  K. Audus,et al.  Permeability properties of monolayers of the human trophoblast cell line BeWo. , 1997, The American journal of physiology.

[47]  A. Marcelis,et al.  Surface charge-specific interactions between polymer nanoparticles and ABC transporters in Caco-2 cells , 2013, Journal of Nanoparticle Research.

[48]  W. D. de Jong,et al.  The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles. , 2011, Biomaterials.

[49]  R. Sakakibara,et al.  Synthesis and secretion of human chorionic gonadotropin and its subunits in choriocarcinoma cells: a comparative study with normal placental cells , 1990, Molecular and Cellular Endocrinology.