Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion.
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[1] A. Velcich,et al. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria , 2008, Proceedings of the National Academy of Sciences.
[2] P. Quinton. Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis , 2008, The Lancet.
[3] A. Witte,et al. The role of serotonin in intestinal luminal sensing and secretion , 2008, Acta physiologica.
[4] P. Verdugo. Hydration kinetics of exocytosed mucins in cultured secretory cells of the rabbit trachea: a new model. , 2008, Ciba Foundation symposium.
[5] R. Tarran,et al. Liquid movement across the surface epithelium of large airways , 2007, Respiratory Physiology & Neurobiology.
[6] R. D. De Lisle,et al. Effects of laxative and N-acetylcysteine on mucus accumulation, bacterial load, transit, and inflammation in the cystic fibrosis mouse small intestine. , 2007, American journal of physiology. Gastrointestinal and liver physiology.
[7] S. Muallem,et al. Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3− secretion: relevance to cystic fibrosis , 2006, The EMBO journal.
[8] Karin Noaksson,et al. Increased levels of mucins in the cystic fibrosis mouse small intestine, and modulator effects of the Muc1 mucin expression. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[9] R. Kuver,et al. Absence of CFTR is associated with pleiotropic effects on mucins in mouse gallbladder epithelial cells. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[10] L. Gawenis,et al. Chloride conductance of CFTR facilitates basal Cl-/HCO3- exchange in the villous epithelium of intact murine duodenum. , 2005, American journal of physiology. Gastrointestinal and liver physiology.
[11] K. Takeuchi,et al. Role of prostaglandin E receptor subtypes in gastroduodenal HCO3- secretion. , 2005, Medicinal chemistry (Shariqah (United Arab Emirates)).
[12] A. Taddei,et al. Discovery of Glycine Hydrazide Pore-occluding CFTR Inhibitors , 2004, The Journal of general physiology.
[13] A. Ouellette,et al. Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[14] B. Rubin,et al. MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions. , 2004, American journal of respiratory cell and molecular biology.
[15] I. Gipson,et al. The role of calcium in mucin packaging within goblet cells. , 2003, Experimental eye research.
[16] J. Filkowski,et al. Control of dynamic CFTR selectivity by glutamate and ATP in epithelial cells , 2003, Nature.
[17] S. Domino,et al. Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2 glycosyltransferase. , 2002, The Biochemical journal.
[18] N. Joo,et al. Mucus Secretion from Single Submucosal Glands of Pig , 2002, The Journal of Biological Chemistry.
[19] S. Ho,et al. Acidic pH and increasing [Ca(2+)] reduce the swelling of mucins in primary cultures of human cervical cells. , 2002, Human reproduction.
[20] L. Clarke,et al. Intestinal bicarbonate secretion in cystic fibrosis mice. , 2001, JOP : Journal of the pancreas.
[21] N. Joo,et al. HCO3- transport in relation to mucus secretion from submucosal glands. , 2001, JOP : Journal of the pancreas.
[22] L. Holm,et al. The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[23] J. Kaunitz,et al. Sensory pathways and cyclooxygenase regulate mucus gel thickness in rat duodenum. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[24] Torben S. D. Johansen,et al. Molecular and functional evidence for electrogenic and electroneutral Na(+)-HCO(3)(-) cotransporters in murine duodenum. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[25] P. Quinton. The neglected ion: HCO3− , 2001, Nature Medicine.
[26] J. Huizinga,et al. The myogenic component in distention-induced peristalsis in the guinea pig small intestine. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[27] Min Goo Lee,et al. Aberrant CFTR-dependent HCO-3 transport in mutations associated with cystic fibrosis , 2001, Nature.
[28] J. Isenberg,et al. Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis. , 2000, Gastroenterology.
[29] W. Finkbeiner. Physiology and pathology of tracheobronchial glands. , 1999, Respiration physiology.
[30] S. Halm,et al. Secretagogue response of goblet cells and columnar cells in human colonic crypts. , 1999, American journal of physiology. Cell physiology.
[31] C. Stanley,et al. Selective secretion and replenishment of discrete mucin glycoforms from intestinal goblet cells. , 1999, American journal of physiology. Gastrointestinal and liver physiology.
[32] A. Verkman,et al. Aquaporin water channels in gastrointestinal physiology , 1999, The Journal of physiology.
[33] H. Ahlman,et al. Involvement of serotonin and calcium channels in the intestinal fluid secretion evoked by bile salt and cholera toxin , 1999, British journal of pharmacology.
[34] B. Tümmler,et al. ΔF508 CFTR protein expression in tissues from patients with cystic fibrosis , 1999 .
[35] J. Lafitte,et al. The sialylation of bronchial mucins secreted by patients suffering from cystic fibrosis or from chronic bronchitis is related to the severity of airway infection. , 1999, Glycobiology.
[36] S. Randell,et al. Evidence for Periciliary Liquid Layer Depletion, Not Abnormal Ion Composition, in the Pathogenesis of Cystic Fibrosis Airways Disease , 1998, Cell.
[37] S. Gendler,et al. Cystic fibrosis mice lacking Muc1 have reduced amounts of intestinal mucus. , 1998, The Journal of clinical investigation.
[38] J. Chayvialle,et al. Effects of neurotransmitters, gut hormones, and inflammatory mediators on mucus discharge in rat colon. , 1998, American journal of physiology. Gastrointestinal and liver physiology.
[39] M. Corboz,et al. Effect of anion secretion inhibitors on mucin content of airway submucosal gland ducts. , 1998, American journal of physiology. Lung cellular and molecular physiology.
[40] H. Rossmann,et al. A functional CFTR protein is required for mouse intestinal cAMP‐, cGMP‐ and Ca2+‐dependent HCO3− secretion , 1997, The Journal of physiology.
[41] J. Isenberg,et al. Acid-stimulated duodenal bicarbonate secretion involves a CFTR-mediated transport pathway in mice. , 1997, Gastroenterology.
[42] U. L. Hayden,et al. Cellular localization of cystic fibrosis transmembrane regulator protein in piglet and mouse intestine , 1996, Cell and Tissue Research.
[43] S. Freedman,et al. Pancreatic Dysfunction in Cystic Fibrosis Occurs as a Result of Impairments in Luminal pH, Apical Trafficking of Zymogen Granule Membranes, and Solubilization of Secretory Enzymes , 1996, Pancreas.
[44] Y Zhang,et al. Genotypic analysis of respiratory mucous sulfation defects in cystic fibrosis. , 1995, The Journal of clinical investigation.
[45] J. Dekker,et al. Mucin gene structure and expression: protection vs. adhesion. , 1995, The American journal of physiology.
[46] E. Nilsson,et al. Mucus and alkali secretion in the rat duodenum: effects of indomethacin, N omega-nitro-L-arginine, and luminal acid. , 1995, Gastroenterology.
[47] T. Machen,et al. Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[48] A. Allen,et al. Gastroduodenal mucosal protection. , 1993, Physiological reviews.
[49] M. King,et al. The disulphide-bond content and rheological properties of intestinal mucins from normal subjects and patients with cystic fibrosis. , 1990, The Biochemical journal.
[50] P. Verdugo,et al. Molecular Mechanism of Mucin Secretion: I. The Role of Intragranular Charge Shielding , 1987, Journal of dental research.
[51] T. Phillips,et al. Regulation of intestinal goblet cell secretion. III. Isolated intestinal epithelium. , 1984, The American journal of physiology.
[52] T. McManus,et al. Bumetanide inhibits (Na + K + 2Cl) co-transport at a chloride site. , 1983, The American journal of physiology.
[53] R. Specian,et al. Regulation of intestinal goblet cell secretion. II. A survey of potential secretagogues. , 1982, The American journal of physiology.
[54] P. Verdugo,et al. Control of mucus hydration as a Donnan equilibrium process , 1981, Nature.
[55] I. Mandel,et al. Composition of nasal secretion in patients with cystic fibrosis. , 1976, The Journal of laboratory and clinical medicine.
[56] H. Shwachman,et al. Water and electrolytes in cervical mucus from patients with cystic fibrosis. , 1973, Fertility and sterility.
[57] P. Vishwakarma. The pH and bicarbonate-ion content of the oviduct and uterine fluids. , 1962, Fertility and sterility.
[58] H. Hodge,et al. SOME ACHIEVEMENTS AND PROBLEMS IN STUDYING THE SOLUBILITY OF THE MINERAL OF THE HARD TISSUES , 1955, Annals of the New York Academy of Sciences.
[59] W. Colledge,et al. Ultrastructural changes in exocrine tissues of a DeltaF-508 CFTR mouse model. , 2001, Pflugers Archiv : European journal of physiology.
[60] W. Colledge,et al. Ultrastructural changes in exocrine tissues of a ΔF-508 CFTR mouse model , 2001, Pflügers Archiv.
[61] B. Tümmler,et al. DeltaF508 CFTR protein expression in tissues from patients with cystic fibrosis. , 1999, The Journal of clinical investigation.
[62] J. Dekker,et al. Gastrointestinal expression and partial cDNA cloning of murine Muc2. , 1999, American journal of physiology. Gastrointestinal and liver physiology.
[63] S. Kirkeby,et al. Quantitative PAS assay of some carbohydrate compounds and detergents. , 1992, Journal of biochemical and biophysical methods.
[64] P. Verdugo. Goblet cells secretion and mucogenesis. , 1990, Annual review of physiology.
[65] Esterly,et al. Pathology of cystic fibrosis review of the literature and comparison with 146 autopsied cases. , 1975, Perspectives in pediatric pathology.