High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
暂无分享,去创建一个
Y. J. Kim | L. Looger | Y. Okada | B. Han | M. Kubo | J. Wren | Y. Kochi | A. Suzuki | S. Bang | Hye-Soon Lee | S. Bae | Kazuhiko Yamamoto | J. Molineros | K. Chua | J. Harley | T. Sumida | Hong Zhang | K. Kaufman | S. Shim | N. Shen | C. Sun | Xu-jie Zhou | Kwangwoo Kim | Jianyang Ma | Y. Qi | X. Kim-Howard | Prasenjeet N Motghare | Krishna Bhattarai | A. Adler | Tae-Hwan Kim | Y. Kang | C. Suh | W. Chung | Yong-Beom Park | J. Choe | Shin-Seok Lee | M. Dozmorov | S. Nath | Krishna Bhattarai | Celi Sun | K. Yamamoto | X. KIM-HOWARD | M. Kubo | S. Bae | Kazuhiko Yamamoto
[1] John D. Storey,et al. Testing for genetic associations in arbitrarily structured populations , 2014, Nature Genetics.
[2] P. Gregersen,et al. High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. , 2015, Annals of the rheumatic diseases.
[3] Guixiu Shi,et al. The GTF2I rs117026326 polymorphism is associated with anti-SSA-positive primary Sjögren's syndrome. , 2015, Rheumatology.
[4] Y. Okada,et al. Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy , 2015, Nature Genetics.
[5] M. Daly,et al. Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants , 2014, Nature.
[6] Y. Okada,et al. The HLA-DRβ1 amino acid positions 11–13–26 explain the majority of SLE–MHC associations , 2014, Nature Communications.
[7] Marylyn D. Ritchie,et al. Imputation and quality control steps for combining multiple genome-wide datasets , 2014, Front. Genet..
[8] L. Looger,et al. Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM. , 2014, Human molecular genetics.
[9] Xinli Hu,et al. SNPsea: an algorithm to identify cell types, tissues and pathways affected by risk loci , 2014, Bioinform..
[10] P. Gaffney,et al. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. , 2014, American journal of human genetics.
[11] Cesare Furlanello,et al. A promoter-level mammalian expression atlas , 2015 .
[12] R. Lahita,et al. Pragmatic approaches to therapy for systemic lupus erythematosus , 2014, Nature Reviews Rheumatology.
[13] Yang Du,et al. rSNPBase: a database for curated regulatory SNPs , 2013, Nucleic Acids Res..
[14] Howard Y. Chang,et al. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position , 2013, Nature Methods.
[15] J. Ott,et al. A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23 , 2013, Nature Genetics.
[16] P. Gaffney,et al. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome , 2013, Nature Genetics.
[17] M. Peters,et al. Systematic identification of trans eQTLs as putative drivers of known disease associations , 2013, Nature Genetics.
[18] S. Boackle. Advances in lupus genetics , 2013, Current opinion in rheumatology.
[19] Anthony J. Kusalik,et al. DAPPLE: a pipeline for the homology-based prediction of phosphorylation sites , 2013, Bioinform..
[20] W. Han,et al. Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls. , 2013, Human molecular genetics.
[21] Q. Chu,et al. Overexpression of hCLP46 enhances Notch activation and regulates cell proliferation in a cell type‐dependent manner , 2013, Cell proliferation.
[22] Pak Chung Sham,et al. GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications , 2013, Nucleic Acids Res..
[23] Paolo Vineis,et al. Genome-wide Association Study Identifies Multiple Risk Loci for Chronic Lymphocytic Leukemia , 2013, Nature Genetics.
[24] Avi Ma'ayan,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[25] Z. Qiu,et al. CD226 Gly307Ser association with multiple autoimmune diseases: a meta-analysis. , 2013, Human immunology.
[26] Scott M. Williams,et al. Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production , 2013, PLoS genetics.
[27] P. Sham,et al. Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. , 2013, American journal of human genetics.
[28] Wei Wang,et al. MaCH‐Admix: Genotype Imputation for Admixed Populations , 2013, Genetic epidemiology.
[29] Ralf Herwig,et al. The ConsensusPathDB interaction database: 2013 update , 2012, Nucleic Acids Res..
[30] Jake K. Byrnes,et al. Bayesian refinement of association signals for 14 loci in 3 common diseases , 2012, Nature Genetics.
[31] J. Rouder,et al. Default Bayes Factors for Model Selection in Regression , 2012, Multivariate behavioral research.
[32] David C. Wilson,et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease , 2012, Nature.
[33] Daniel J. Gaffney,et al. Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis , 2012, Nature Genetics.
[34] ENCODEConsortium,et al. An Integrated Encyclopedia of DNA Elements in the Human Genome , 2012, Nature.
[35] R. Kooy,et al. The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome. , 2012, American journal of human genetics.
[36] P. Gaffney,et al. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. , 2012, American journal of human genetics.
[37] Masao Ueki,et al. Improved Statistics for Genome-Wide Interaction Analysis , 2012, PLoS genetics.
[38] R. Jessberger,et al. Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity , 2012, The Journal of experimental medicine.
[39] Stephen J. Palmer,et al. Mutation of Gtf2ird1 from the Williams–Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations , 2012, Neurobiology of Disease.
[40] Namhee Kwon,et al. Systematic review of the epidemiology of systemic lupus erythematosus in the Asia‐Pacific region: Prevalence, incidence, clinical features, and mortality , 2012, Arthritis care & research.
[41] A. Roy. Biochemistry and biology of the inducible multifunctional transcription factor TFII-I: 10 years later. , 2012, Gene.
[42] Y. Okada,et al. A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese , 2012, PLoS genetics.
[43] P. Gaffney,et al. Analysis of autosomal genes reveals gene–sex interactions and higher total genetic risk in men with systemic lupus erythematosus , 2011, Annals of the rheumatic diseases.
[44] Manolis Kellis,et al. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants , 2011, Nucleic Acids Res..
[45] Juan-Manuel Anaya,et al. Evaluation of 19 Autoimmune Disease-associated Loci with Rheumatoid Arthritis in a Colombian Population: Evidence for Replication and Gene-Gene Interaction , 2011, The Journal of Rheumatology.
[46] P. Sham,et al. Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases , 2011, Genetic epidemiology.
[47] M. Brown,et al. Promise and pitfalls of the Immunochip , 2011, Arthritis research & therapy.
[48] F. Wang,et al. Association of the CD226 single nucleotide polymorphism with systemic lupus erythematosus in the Chinese Han population. , 2011, Tissue antigens.
[49] M. Daly,et al. Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets. , 2011, American journal of human genetics.
[50] Xavier Robin,et al. pROC: an open-source package for R and S+ to analyze and compare ROC curves , 2011, BMC Bioinformatics.
[51] Yun Li,et al. METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..
[52] J. Anaya,et al. Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases. , 2010, Rheumatology.
[53] David N. Rider,et al. Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” , 2010, PLoS genetics.
[54] Liangdan Sun,et al. TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population , 2010, Lupus.
[55] A. Alcina,et al. The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis , 2010, Genes and Immunity.
[56] G. Bejerano,et al. GREAT improves functional interpretation of cis-regulatory regions , 2010, Nature Biotechnology.
[57] Qiang Yang,et al. BOOST: A fast approach to detecting gene-gene interactions in genome-wide case-control studies , 2010, American journal of human genetics.
[58] C. Fauth,et al. Partial 7q11.23 deletions further implicate GTF2I and GTF2IRD1 as the main genes responsible for the Williams–Beuren syndrome neurocognitive profile , 2009, Journal of Medical Genetics.
[59] Gerald McGwin,et al. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus , 2009, Nature Genetics.
[60] P. Iatropoulos,et al. Association study and mutational screening of SYNGR1 as a candidate susceptibility gene for schizophrenia , 2009, Psychiatric genetics.
[61] A. Perl. Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome , 2009, Current opinion in rheumatology.
[62] A. Chan,et al. Novel association of the CD226 (DNAM-1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patients , 2009, Genes and Immunity.
[63] C. Langefeld,et al. Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies , 2009, Nature Reviews Genetics.
[64] Joseph K. Pickrell,et al. Signals of recent positive selection in a worldwide sample of human populations. , 2009, Genome research.
[65] J. Todd,et al. CD226 Gly307Ser association with multiple autoimmune diseases , 2009, Genes and Immunity.
[66] G. Abecasis,et al. Genotype imputation. , 2009, Annual review of genomics and human genetics.
[67] T. Yasui,et al. Accelerated tumor growth in mice deficient in DNAM-1 receptor , 2008, The Journal of experimental medicine.
[68] I. Sadowski,et al. Specific interaction of TFII‐I with an upstream element on the HIV‐1 LTR regulates induction of latent provirus , 2008, FEBS letters.
[69] Marta E Alarcón-Riquelme,et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci , 2008, Nature Genetics.
[70] T. Koike,et al. Defective Expression of Ras Guanyl Nucleotide-Releasing Protein 1 in a Subset of Patients with Systemic Lupus Erythematosus1 , 2007, The Journal of Immunology.
[71] Manuel A. R. Ferreira,et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.
[72] T. Behrens,et al. A distinct inflammatory gene expression profile in patients with psoriatic arthritis , 2006, Genes and Immunity.
[73] R. Melamed,et al. Gene expression microarrays: glimpses of the immunological genome , 2006, Nature Immunology.
[74] J. Satia,et al. Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden , 2006, Lupus.
[75] J. Pritchard,et al. A Map of Recent Positive Selection in the Human Genome , 2006, PLoS biology.
[76] W. Klapper,et al. Telomerase activity in B and T lymphocytes of patients with systemic lupus erythematosus , 2004, Annals of the rheumatic diseases.
[77] S. Batalov,et al. A gene atlas of the mouse and human protein-encoding transcriptomes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[78] P. Sharp,et al. Regulation of Immunoglobulin Promoter Activity by TFII-I Class Transcription Factors* , 2004, Journal of Biological Chemistry.
[79] Jonathan D. Wren,et al. Knowledge discovery by automated identification and ranking of implicit relationships , 2004, Bioinform..
[80] J. Fanzo,et al. T Cell Receptor Engagement Leads to the Recruitment of IBP, a Novel Guanine Nucleotide Exchange Factor, to the Immunological Synapse* , 2003, Journal of Biological Chemistry.
[81] Loise M. Francisco,et al. A set of genes selectively expressed in murine dendritic cells: utility of related cis-acting sequences for lentiviral gene transfer. , 2003, Molecular immunology.
[82] Gary Peltz,et al. A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. , 2003, Diabetes.
[83] E. Wakeland,et al. The genetics of complex autoimmune diseases: non-MHC susceptibility genes , 2001, Nature Immunology.
[84] K. Gish,et al. OB-BP1/Siglec-6 , 1999, The Journal of Biological Chemistry.
[85] N Risch,et al. The Future of Genetic Studies of Complex Human Diseases , 1996, Science.
[86] E. DeLong,et al. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. , 1988, Biometrics.