A simple and label-free sensor for mercury(II) detection in aqueous solution by malachite green based on a resonance scattering spectral assay.

Mercury ions (Hg(2+)) can specifically interact with the thymine-rich Hg(2+) aptamer and malachite green (MG) to form the Hg(2+) aptamer-MG-Hg(2+) complex, inducing the increase of resonance scattering (RS) intensity at 611 nm, which enables the label-free detection of Hg(2+) in aqueous solution with high selectivity and a detection limit of 1.7 nM.

[1]  Chunying Duan,et al.  "Turn-on" fluorescent sensor for Hg2+ via displacement approach. , 2008, Inorganic chemistry.

[2]  Yangyang Zhou,et al.  The sensitive and selective optical detection of mercury(II) ions by using a phosphorothioate DNAzyme strategy. , 2009, Chemistry.

[3]  Z. Deng,et al.  Colorimetric Hg2+ detection with a label-free and fully DNA-structured sensor assembly incorporating G-quadruplex halves. , 2009, The Analyst.

[4]  Yanyan Fan,et al.  A highly selective nanogold-aptamer catalytic resonance scattering spectral assay for trace Hg(2+) using HAuCl(4)-ascorbic acid as indicator reaction. , 2010, Talanta.

[5]  E. Wang,et al.  Carbon nanotube-DNA hybrid fluorescent sensor for sensitive and selective detection of mercury(II) ion. , 2010, Chemical communications.

[6]  Juewen Liu,et al.  Functional nucleic acid sensors. , 2009, Chemical reviews.

[7]  Martin Moskovits,et al.  Detection of sequence-specific protein-DNA interactions via surface enhanced resonance Raman scattering. , 2007, Journal of the American Chemical Society.

[8]  Chunhai Fan,et al.  Optical Detection of Mercury(II) in Aqueous Solutions by Using Conjugated Polymers and Label‐Free Oligonucleotides , 2007 .

[9]  M. Reddy,et al.  A new Hg(2+) -selective fluorescent sensor based on a 1,3-alternate thiacalix[4]arene anchored with four 8-quinolinoloxy groups. , 2007, Inorganic chemistry.

[10]  Evan W. Miller,et al.  A bright and specific fluorescent sensor for mercury in water, cells, and tissue. , 2007, Angewandte Chemie.

[11]  Yanyan Fan,et al.  Resonance scattering spectral detection of trace Hg2+ using aptamer-modified nanogold as probe and nanocatalyst. , 2009, Analytical chemistry.

[12]  Li Li,et al.  Label-free aptamer-based colorimetric detection of mercury ions in aqueous media using unmodified gold nanoparticles as colorimetric probe , 2009, Analytical and bioanalytical chemistry.

[13]  Wei Yang,et al.  Peroxidase activity-structure relationship of the intermolecular four-stranded G-quadruplex-hemin complexes and their application in Hg2+ ion detection. , 2009, Talanta.

[14]  Yi Lu,et al.  Rational design of "turn-on" allosteric DNAzyme catalytic beacons for aqueous mercury ions with ultrahigh sensitivity and selectivity. , 2007, Angewandte Chemie.

[15]  Fan Yang,et al.  Colorimetric biosensing of mercury(II) ion using unmodified gold nanoparticle probes and thrombin-binding aptamer. , 2010, Biosensors & bioelectronics.

[16]  E. Wang,et al.  Label-free colorimetric detection of aqueous mercury ion (Hg2+) using Hg2+-modulated G-quadruplex-based DNAzymes. , 2009, Analytical chemistry.

[17]  Guonan Chen,et al.  Highly sensitive fluorescent sensor for mercury ion based on photoinduced charge transfer between fluorophore and pi-stacked T-Hg(II)-T base pairs. , 2009, Talanta.

[18]  W. Smith,et al.  Quantitative simultaneous multianalyte detection of DNA by dual-wavelength surface-enhanced resonance Raman scattering. , 2007, Angewandte Chemie.

[19]  Yi Lu,et al.  Highly sensitive "turn-on" fluorescent sensor for Hg2+ in aqueous solution based on structure-switching DNA. , 2008, Chemical communications.

[20]  Tao Li,et al.  G-quadruplex-based DNAzyme for sensitive mercury detection with the naked eye. , 2009, Chemical communications.

[21]  Stephen J Lippard,et al.  A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media. , 2003, Journal of the American Chemical Society.

[22]  H. Katerinopoulos,et al.  A "turn-on" coumarin-based fluorescent sensor with high selectivity for mercury ions in aqueous media. , 2010, Chemical communications.