Myositis ossificans circumscripta in para/tetraplegics.

At the Hospital of Physical Medicine, Hornbaek, we analysed in retrospect 52 cases of myositis ossificans circumscripta (MOC) among 605 patients with para/tetraplegia. MOC proved significantly more common after total than after subtotal spinal cord injuries. MOC was not observed in any case above the motor level of the spinal cord lesion. This neurological relationship appears to "explain" the finding that MOC is more common in para/tetraplegia of traumatic origin (more complete spinal cord lesions) than among those caused by slipped discs or tumours. Twenty-five per cent of the patients ended up with fairly mild and 12% with more severe hip contractures, the latter causing recurrent, contralateral decubital ulcers over the ischial tuberosity and protracted hospitalization. To aid diagnosis, the authors suggest a simple programme for all para/tetraplegics. In our opinion, routine X-ray examination is not necessary. Intensified research into the causative factors and treatment is needed, not only to facilitate these patients' social adaptation, but also for socio-economic reasons.

[1]  D. Ogilvie-Harris,et al.  Pseudomalignant myositis ossificans: heterotopic new-bone formation without a history of trauma. , 1980, The Journal of bone and joint surgery. American volume.

[2]  L. Staheli,et al.  Fibrodysplasia ossificans progressiva (myositis ossificans progressiva) treatment with disodium etidronate. , 1979, Jornal de Pediatria.

[3]  S. Ljunghall,et al.  Myositis ossificans progressiva. Clinical and metabolical observations in a case treated with a diphosphonate (EHDP) and surgical removal of ectopic bone. , 1979, Acta orthopaedica Scandinavica.

[4]  J. Forner,et al.  The para-articular ossifications in our paraplegics and tetraplegics: a survey of 704 patients , 1978, Paraplegia.

[5]  M. Urist,et al.  Experimental myositis ossificans: cartilage and bone formation in muscle in response to a diffusible bone matrix-derived morphogen. , 1978, Archives of pathology & laboratory medicine.

[6]  R. Steckel,et al.  Diagnostic oncology case studies. Heterotopic new bone formation: myositis ossificans versus malignant tumor. , 1978, AJR. American journal of roentgenology.

[7]  J. Ph.  Traumatic myositis ossificans. , 1977 .

[8]  S. Spicer,et al.  Histochemical and ultrastructural studies in fibrodysplasia ossificans progressiva (myositis ossificans progressiva). , 1977, The American journal of pathology.

[9]  I. Yaghmai.  Myositis ossificans: diagnostic value of arteriography. , 1977, AJR. American journal of roentgenology.

[10]  B. Bose,et al.  Myositis ossificans due to hockey injury. , 1977, Canadian Medical Association journal.

[11]  G. Asboe-hansen,et al.  Ultrastructure of dermal connective tissue in fibrodysplasia ossificians progressiva. , 1977, Acta Dermato-Venereologica.

[12]  R. McGuirk,et al.  Treatment of traumatic myositis ossificans circumscripta; use of aspiration and steroids. , 1976, The Journal of trauma.

[13]  A. Scher,et al.  The incidence of ectopic bone formation in post-traumatic paraplegic patients of different racial groups , 1976, Paraplegia.

[14]  P. Glenting.  [Myositis ossificans progressiva treated with diphosphonate]. , 1976, Ugeskrift for læger.

[15]  S. Berrol.  Letter: Myositis ossificans: a problem of terminology. , 1976, Journal of the American Medical Association (JAMA).

[16]  R. Russell,et al.  Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment. , 1976, The Journal of bone and joint surgery. British volume.

[17]  A. Goldman.  Myositis ossificans circumscripta: a benign lesion with a malignant differential diagnosis. , 1976, AJR. American journal of roentgenology.

[18]  R. Lagier,et al.  Pseudomalignant myositis ossificans. A pathological study of eight cases. , 1975, Human pathology.

[19]  Stover Sl,et al.  Heterotopic ossification in spinal cord-injured patients. , 1975, Archives of physical medicine and rehabilitation.

[20]  R. Smith,et al.  Myositis ossificans progressiva: a review of current problems. , 1975, Seminars in arthritis and rheumatism.

[21]  Nicholas Jj.  Ectopic bone formation in patients with spinal cord injury. , 1973 .

[22]  R. Illingworth.  Myositis Ossificans Progressiva (Munchmeyer's Disease) , 1971, Archives of disease in childhood.

[23]  D. Femi-pearse,et al.  Myositis ossificans--a complication of tetanus. , 1971, Clinical radiology.

[24]  R. Illingworth,et al.  Myositis Ossificans Progressiva (Munchmeyer's Disease) , 1971, Archives of disease in childhood.

[25]  J. Nicholas,et al.  Elevation of the serum alkaline phosphatase coincident with ectopic-bone formation in paraplegic patients. , 1970, The Journal of bone and joint surgery. American volume.

[26]  M. Dyson,et al.  The stimulation of tissue regeneration by means of ultrasound. , 1968, Clinical science.

[27]  C. Venables,et al.  An Unusual Case of Myositis Ossificans , 1967, Proceedings of the Royal Society of Medicine.

[28]  L. Lutwak.  MYOSITIS OSSIFICANS PROGRESSIVA. MINERAL, METABOLIC AND RADIOACTIVE CALCIUM STUDIES OF THE EFFECTS OF HORMONES. , 1964, The American journal of medicine.

[29]  W. Roberts,et al.  Periarticular Ossification Following Burns , 1959, Southern medical journal.

[30]  G. Asboe-hansen,et al.  Mast cells and tissue water: studies on living connective tissue in the hamster cheek pouch. , 1956, Experimental cell research.