Efficient organocatalytic asymmetric synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives

[1]  D. Du,et al.  Squaramide-catalyzed enantioselective Michael addition of malononitrile to chalcones. , 2012, Organic & biomolecular chemistry.

[2]  C. Zhao,et al.  Organocatalyzed enantioselective synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates. , 2011, Tetrahedron letters.

[3]  J. Wang,et al.  Enantioselective Organocatalytic Synthesis of Medicinally Privileged 2-Amino-4H-chromene-3-carbonitriles via a Cascade Process. , 2011 .

[4]  D. Du,et al.  Chiral squaramide-catalyzed highly diastereo- and enantioselective direct Michael addition of nitroalkanes to nitroalkenes. , 2011, Chemical communications.

[5]  Hai-Bing Zhou,et al.  C3‐Symmetrical Cinchonine‐Squaramide as New Highly Efficient, and Recyclable Organocatalyst for Enantioselective Michael Addition , 2011 .

[6]  Weiliang Chen,et al.  Enantioselective one-pot synthesis of 2-amino-4-(indol-3-yl)-4H-chromenes. , 2011, Organic letters.

[7]  S. Muthusubramanian,et al.  Efficient atom economical one-pot multicomponent synthesis of densely functionalized 4H-chromene derivatives , 2011 .

[8]  Z. Du,et al.  Expeditious assembly of a 2-amino-4H-chromene skeleton by using an enantioselective Mannich intramolecular ring cyclization-tautomerization cascade sequence. , 2011, Chemistry.

[9]  K. Jørgensen,et al.  Squaramides: bridging from molecular recognition to bifunctional organocatalysis. , 2011, Chemistry.

[10]  D. Du,et al.  Chiral Squaramide-Catalyzed Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes , 2011 .

[11]  R. I. Storer,et al.  Squaramides: physical properties, synthesis and applications. , 2011, Chemical Society reviews.

[12]  Lili Lin,et al.  Efficient Asymmetric Synthesis of 4H‐Chromene Derivatives through a Tandem Michael Addition–Cyclization Reaction Catalyzed by a Salen–Cobalt(II) Complex , 2011 .

[13]  A. Bazgir,et al.  New HA 14-1 analogues: synthesis of 2-amino-4-cyano-4H-chromenes , 2010 .

[14]  D. Du,et al.  Highly enantioselective Michael addition of nitroalkanes to chalcones using chiral squaramides as hydrogen bonding organocatalysts. , 2010, Organic letters.

[15]  Fen-Er Chen,et al.  A Bifunctional Cinchona Alkaloid‐Squaramide Catalyst for the Highly Enantioselective Conjugate Addition of Thiols to trans‐Chalcones , 2010 .

[16]  A. Chizhov,et al.  Solvent-free cascade reaction: direct multicomponent assembling of 2-amino-4H-chromene scaffold from salicylaldehyde, malononitrile or cyanoacetate and nitroalkanes , 2010 .

[17]  Zhen-yuan Xu,et al.  Chiral squaramides as highly enantioselective catalysts for Michael addition reactions of 4-hydroxycoumarins and 4-hydroxypyrone to beta,gamma-unsaturated alpha-keto esters. , 2010, Chemistry.

[18]  C. Zhao,et al.  Organocatalyzed synthesis of 2-amino-8-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitriles. , 2010, Tetrahedron letters.

[19]  V. Rawal,et al.  Squaramide-catalyzed enantioselective Michael addition of diphenyl phosphite to nitroalkenes. , 2010, Angewandte Chemie.

[20]  Y. Wen,et al.  Efficient Method for the Synthesis of Optically Active 2‐Amino‐2‐chromene Derivatives via One‐Pot Tandem Reactions , 2009 .

[21]  Sanjay Kumar,et al.  Tetrabutylammonium bromide (TBAB): a neutral and efficient catalyst for the synthesis of biscoumarin and 3,4-dihydropyrano[c]chromene derivatives in water and solvent-free conditions , 2009 .

[22]  C. Zhao,et al.  Organocatalyzed enantioselective synthesis of 6-amino-5-cyanodihydropyrano[2,3-c]pyrazoles. , 2009, Tetrahedron letters.

[23]  V. Rawal,et al.  Chiral squaramide derivatives are excellent hydrogen bond donor catalysts. , 2008, Journal of the American Chemical Society.

[24]  W. Wulff,et al.  Enantioselective organocatalytic direct Michael addition of nitroalkanes to nitroalkenes promoted by a unique bifunctional DMAP-thiourea. , 2008, Journal of the American Chemical Society.

[25]  C. Yao,et al.  Fluoride ion catalyzed multicomponent reactions for efficient synthesis of 4H-chromene and N-arylquinoline derivatives in aqueous media , 2008 .

[26]  D. Du,et al.  Organocatalytic highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes. , 2008, Organic letters.

[27]  Gang Zhao,et al.  Enantioselective synthesis of naphthopyran derivatives catalyzed by bifunctional thiourea-tertiary amines , 2008 .

[28]  Xiaojun Wu,et al.  Chiral amine-thioureas bearing multiple hydrogen bonding donors: highly efficient organocatalysts for asymmetric Michael addition of acetylacetone to nitroolefins. , 2008, Chemical communications.

[29]  D. Du,et al.  The development of double axially chiral phosphoric acids and their catalytic transfer hydrogenation of quinolines. , 2008, Angewandte Chemie.

[30]  S. Balalaie,et al.  Novel and efficient catalysts for the one-pot synthesis of 3,4-dihydropyrano[c]chromene derivatives in aqueous media , 2007 .

[31]  Jun‐An Ma,et al.  Highly enantioselective Michael addition of aromatic ketones to nitroolefins promoted by chiral bifunctional primary amine-thiourea catalysts based on saccharides. , 2007, Organic letters.

[32]  P. Dalko Enantioselective organocatalysis : reactions and experimental procedures , 2007 .

[33]  S. Connon Organocatalysis mediated by (thio)urea derivatives. , 2006, Chemistry.

[34]  Yong Tang,et al.  Pyrrolidine-thiourea as a bifunctional organocatalyst: highly enantioselective Michael addition of cyclohexanone to nitroolefins. , 2006, Organic letters.

[35]  E. Jacobsen,et al.  Highly enantioselective direct conjugate addition of ketones to nitroalkenes promoted by a chiral primary amine-thiourea catalyst. , 2006, Journal of the American Chemical Society.

[36]  J. Pelkonen,et al.  HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells. , 2006, Leukemia research.

[37]  Mark S. Taylor,et al.  Asymmetric catalysis by chiral hydrogen-bond donors. , 2006, Angewandte Chemie.

[38]  Y. Takemoto,et al.  Recognition and activation by ureas and thioureas: stereoselective reactions using ureas and thioureas as hydrogen-bonding donors. , 2005, Organic & biomolecular chemistry.

[39]  William E. Kemnitzer,et al.  Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions. , 2005, Bioorganic & medicinal chemistry letters.

[40]  S. Connon,et al.  Urea- and thiourea-substituted cinchona alkaloid derivatives as highly efficient bifunctional organocatalysts for the asymmetric addition of malonate to nitroalkenes: inversion of configuration at C9 dramatically improves catalyst performance. , 2005, Angewandte Chemie.

[41]  Jinxing Ye,et al.  Enantioselective organocatalytic Michael addition of malonate esters to nitro olefins using bifunctional cinchonine derivatives. , 2005, Chemical communications.

[42]  F. Diederich,et al.  Book review: Metal-catalyzed cross-coupling reactions. F. Diederich and P. J. Stang (eds) Wiley–VCH, Weinheim, 1998. xxi + 517 pages, £85 ISBN 3–527–29421–X , 1998 .

[43]  Y. Takemoto,et al.  Enantio- and diastereoselective Michael reaction of 1,3-dicarbonyl compounds to nitroolefins catalyzed by a bifunctional thiourea. , 2005, Journal of the American Chemical Society.

[44]  H. Gourdeau,et al.  Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4H-chromenes, a novel series of anticancer agents. , 2004, Molecular cancer therapeutics.

[45]  Y. Takemoto,et al.  Enantioselective Michael reaction of malonates to nitroolefins catalyzed by bifunctional organocatalysts. , 2003, Journal of the American Chemical Society.

[46]  R. Maggi,et al.  Three‐Component Process for the Synthesis of 2‐Amino‐2‐chromenes in Aqueous Media. , 2001 .