PDZD8-mediated endoplasmic reticulum–mitochondria associations regulate sympathetic drive and blood pressure through the intervention of neuronal mitochondrial homeostasis in stress-induced hypertension

[1]  J Pierard,et al.  Amyloid , 2023, Arthritis and rheumatism.

[2]  Dongshu Du,et al.  Up‐regulation of miR‐335 and miR‐674‐3p in the rostral ventrolateral medulla contributes to stress‐induced hypertension , 2022, Journal of neurochemistry.

[3]  Y. Li,et al.  Effects of Nrf1 in Hypothalamic Paraventricular Nucleus on Regulating the Blood Pressure During Hypertension , 2021, Frontiers in Neuroscience.

[4]  S. Morrison,et al.  Central sympathetic network for thermoregulatory responses to psychological stress , 2021, Autonomic Neuroscience.

[5]  Dongshu Du,et al.  PLIN2 Mediates Neuroinflammation and Oxidative/Nitrosative Stress via Downregulating Phosphatidylethanolamine in the Rostral Ventrolateral Medulla of Stressed Hypertensive Rats , 2021, Journal of inflammation research.

[6]  Y. Im,et al.  Structural basis of human PDZD8–Rab7 interaction for the ER-late endosome tethering , 2021, Scientific Reports.

[7]  Jing-Cai Liu,et al.  Melatonin reverses mitochondria dysfunction and oxidative stress-induced apoptosis of Sudan I-exposed mouse oocytes. , 2021, Ecotoxicology and environmental safety.

[8]  Haifeng Zhang,et al.  The Role of Mitochondria in Liver Ischemia-Reperfusion Injury: From Aspects of Mitochondrial Oxidative Stress, Mitochondrial Fission, Mitochondrial Membrane Permeable Transport Pore Formation, Mitophagy, and Mitochondria-Related Protective Measures , 2021, Oxidative medicine and cellular longevity.

[9]  Lei Yin,et al.  USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites , 2021, The Journal of cell biology.

[10]  David J. Margolis,et al.  The role of mitophagy in the regulation of mitochondrial energetic status in neurons , 2021, Autophagy.

[11]  J. Rieusset,et al.  Metformin Reverses the Enhanced Myocardial SR/ER–Mitochondria Interaction and Impaired Complex I-Driven Respiration in Dystrophin-Deficient Mice , 2021, Frontiers in Cell and Developmental Biology.

[12]  H. Jaeschke,et al.  Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure. , 2021, Toxicological sciences : an official journal of the Society of Toxicology.

[13]  E. Metzakopian,et al.  ER-mitochondria contact sites in neurodegeneration: genetic screening approaches to investigate novel disease mechanisms , 2020, Cell Death & Differentiation.

[14]  Q. Foguet-Boreu,et al.  [Psychosocial stress, high blood pressure and cardiovascular risk]. , 2020, Hipertension y riesgo vascular.

[15]  Wei Gao,et al.  Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice. , 2020, Clinical science.

[16]  M. Harel,et al.  PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria , 2020, Nature Communications.

[17]  C. Troakes,et al.  Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain , 2020, Neurobiology of Disease.

[18]  P. Mercier,et al.  The ER chaperone calnexin controls mitochondrial positioning and respiration , 2020, Science Signaling.

[19]  R. Stornetta,et al.  Neuronal Networks in Hypertension , 2020, Hypertension.

[20]  G. Aguiari,et al.  The mystery of mitochondria-ER contact sites in physiology and pathology: A cancer perspective. , 2020, Biochimica et biophysica acta. Molecular basis of disease.

[21]  Peng Gao,et al.  Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes. , 2020, Metabolism: clinical and experimental.

[22]  Hongji Li,et al.  HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia , 2020, Journal of Neuroinflammation.

[23]  P. Lazarovici,et al.  Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway , 2019, Stem Cell Research & Therapy.

[24]  Yu-Ming Kang,et al.  Exercise Training Attenuates Hypertension Through TLR4/MyD88/NF-κB Signaling in the Hypothalamic Paraventricular Nucleus , 2019, Front. Neurosci..

[25]  T. Wisniewski,et al.  Perturbed mitochondria–ER contacts in live neurons that model the amyloid pathology of Alzheimer's disease , 2019, Journal of Cell Science.

[26]  Alan R. Lowe,et al.  Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery , 2019, Nature Communications.

[27]  R. Zoncu,et al.  ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signaling in Niemann-Pick type C , 2019, Nature Cell Biology.

[28]  R. Zoncu,et al.  ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C , 2019, Nature Cell Biology.

[29]  Z. Sheng,et al.  Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts , 2019, Nature Communications.

[30]  W. Noble,et al.  The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity , 2019, Acta neuropathologica communications.

[31]  Lin-lin Shen,et al.  Central blockade of the AT1 receptor attenuates pressor effects via reduction of glutamate release and downregulation of NMDA/AMPA receptors in the rostral ventrolateral medulla of rats with stress-induced hypertension , 2019, Hypertension Research.

[32]  C. Villalobos,et al.  Amyloid β Oligomers Increase ER-Mitochondria Ca2+ Cross Talk in Young Hippocampal Neurons and Exacerbate Aging-Induced Intracellular Ca2+ Remodeling , 2019, Front. Cell. Neurosci..

[33]  C. Angelini,et al.  Regulation of ER‐mitochondria contacts by Parkin via Mfn2 , 2018, Pharmacological research.

[34]  Dongshu Du,et al.  Upregulation of Nav1.6 expression in the rostral ventrolateral medulla of stress-induced hypertensive rats , 2018, Hypertension Research.

[35]  R. Stornetta,et al.  Rostral Ventrolateral Medulla and Hypertension , 2018, Hypertension.

[36]  K. Itahana,et al.  p32 regulates ER stress and lipid homeostasis by down‐regulating GCS1 expression , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[37]  O. Redina,et al.  Stress, Genes, and Hypertension. Contribution of the ISIAH Rat Strain Study , 2018, Current Hypertension Reports.

[38]  W. Shang,et al.  A novel fluorescent reporter detects plastic remodeling of mitochondria–ER contact sites , 2018, Journal of Cell Science.

[39]  Yusuke Hirabayashi,et al.  ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons , 2017, Science.

[40]  Dongshu Du,et al.  Neuroinflammation contributes to autophagy flux blockage in the neurons of rostral ventrolateral medulla in stress-induced hypertension rats , 2017, Journal of Neuroinflammation.

[41]  L. Massieu,et al.  Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons , 2017, Cell Death and Disease.

[42]  P. Reddy,et al.  Mitochondrial dysfunction and oxidative stress in metabolic disorders - A step towards mitochondria based therapeutic strategies. , 2017, Biochimica et biophysica acta. Molecular basis of disease.

[43]  William A. Li,et al.  Association between psychosocial stress and hypertension: a systematic review and meta-analysis , 2017, Neurological research.

[44]  C. McMaster,et al.  Lipid synthesis and membrane contact sites: a crossroads for cellular physiology , 2016, Journal of Lipid Research.

[45]  Caitlyn W. Barrett,et al.  α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease , 2016, Science Translational Medicine.

[46]  Christopher C. J. Miller,et al.  There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases , 2016, Trends in Neurosciences.

[47]  S. Schmid,et al.  Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis , 2016, Molecular metabolism.

[48]  Juxiang Yuan,et al.  Effects of Psychological Stress on Hypertension in Middle-Aged Chinese: A Cross-Sectional Study , 2015, PloS one.

[49]  T. Dong,et al.  Role of the Renin-Angiotensin System, Renal Sympathetic Nerve System, and Oxidative Stress in Chronic Foot Shock-Induced Hypertension in Rats , 2015, International journal of biological sciences.

[50]  Julian F. R. Paton,et al.  Essential role of RVL medullary neuronal activity in the long term maintenance of hypertension in conscious SHR , 2014, Autonomic Neuroscience.

[51]  D. McDougal,et al.  Leptin into the rostral ventral lateral medulla (RVLM) augments renal sympathetic nerve activity and blood pressure , 2014, Front. Neurosci..

[52]  Nathan A. Bihlmeyer,et al.  Transcellular degradation of axonal mitochondria , 2014, Proceedings of the National Academy of Sciences.

[53]  L. Petrucelli,et al.  ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 , 2014, Nature Communications.

[54]  M. Chesselet,et al.  Mitochondrial dysfunction and oxidative stress in Parkinson's disease , 2013, Progress in Neurobiology.

[55]  M. Blettner,et al.  Association of hypertension with depression in the community: results from the Gutenberg Health Study , 2013, Journal of hypertension.

[56]  T. Saruta,et al.  Importance of rostral ventrolateral medulla neurons in determining efferent sympathetic nerve activity and blood pressure , 2011, Hypertension Research.

[57]  Matthew West,et al.  ER Tubules Mark Sites of Mitochondrial Division , 2011, Science.

[58]  G. Hajnóczky,et al.  Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress , 2011, Cell Death and Differentiation.

[59]  P. Fadel,et al.  Therapeutic strategies for targeting excessive central sympathetic activation in human hypertension , 2010, Experimental physiology.

[60]  N. Durany,et al.  Oxidative stress in Alzheimer disease , 2009, Cell adhesion & migration.

[61]  J. Sowers,et al.  Role of mitochondrial dysfunction in insulin resistance. , 2008, Circulation research.

[62]  M. Fontes,et al.  Cardiovascular effects produced by activation of GABA receptors in the rostral ventrolateral medulla of conscious rats , 2007, Neuroscience.

[63]  C. Mannella,et al.  Structural and functional features and significance of the physical linkage between ER and mitochondria , 2006, The Journal of cell biology.

[64]  T. Yao,et al.  [Angiotensin II participates in stress-induced high blood pressure via stimulating hypothalamic vasopressin synthesis and release]. , 2000, Sheng li xue bao : [Acta physiologica Sinica].

[65]  Lawrence M. Lifshitz,et al.  Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. , 1998, Science.

[66]  G. Brewer,et al.  Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination , 1993, Journal of neuroscience research.

[67]  A. Mark,et al.  Mental stress increases sympathetic nerve activity during sustained baroreceptor stimulation in humans. , 1991, Hypertension.

[68]  J. Vance.  Phospholipid synthesis in a membrane fraction associated with mitochondria. , 1990, The Journal of biological chemistry.

[69]  J. Connell,et al.  Effects of ACTH and Cortisol Administration on Blood Pressure, Electrolyte Metabolism, Atrial Natriuretic Peptide and Renal Function in Normal Man , 1987, Journal of hypertension.

[70]  K. Hagbarth,et al.  Comparison of Sympathetic Nerve Activity in Normotensive and Hypertensive Subjects , 1973, Circulation research.

[71]  R. Fuller,et al.  Functional Significance of the Sympathetic Nervous System in Production of Hypertension , 1969, Nature.

[72]  K. Minematsu,et al.  Risk Factors. , 2016, Frontiers of neurology and neuroscience.

[73]  S. Kotani,et al.  Structural and Functional Features , 2011 .

[74]  Matthew W. Miller,et al.  Culturing hippocampal and cortical neurons. , 2003, Methods in cell biology.

[75]  P. Wolf,et al.  American Heart Association Prevention Conference. IV. Prevention and Rehabilitation of Stroke. Risk factors. , 1997, Stroke.

[76]  J. Whitworth,et al.  Blood pressure and metabolic effects of cortisol and deoxycorticosterone in man. , 1984, Clinical and experimental hypertension. Part A, Theory and practice.

[77]  S. Nozoe,et al.  Stress and hypertension. , 1982, Contributions to nephrology.

[78]  P. Imhof,et al.  Über Blutdrucksteigerung bei psychischer Belastung , 1957 .