The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the development and function of the blood-brain barrier.

[1]  R. Daneman,et al.  The blood-brain barrier. , 2015, Cold Spring Harbor perspectives in biology.

[2]  D. Gao,et al.  Egr-1 participates in abnormally high gdnf gene transcription mediated by histone hyperacetylation in glioma cells. , 2014, Biochimica et biophysica acta.

[3]  Shijie Jin,et al.  Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes , 2014, PloS one.

[4]  Douglas R Martin,et al.  Recent advances in delivery through the blood-brain barrier. , 2014, Current topics in medicinal chemistry.

[5]  D. Gao,et al.  Hyperacetylation of Histone H3K9 Involved in the Promotion of Abnormally High Transcription of the gdnf Gene in Glioma Cells , 2014, Molecular Neurobiology.

[6]  R. Ransohoff,et al.  Development, maintenance and disruption of the blood-brain barrier , 2013, Nature Medicine.

[7]  A. Wójtowicz,et al.  Impact of endocrine-disrupting chemicals on neural development and the onset of neurological disorders , 2013, Pharmacological reports : PR.

[8]  Y. Huang,et al.  Recombinant Human Sonic Hedgehog Protein Regulates the Expression of ZO-1 and Occludin by Activating Angiopoietin-1 in Stroke Damage , 2013, PloS one.

[9]  K. Selvakumar,et al.  Polychlorinated biphenyls impair blood–brain barrier integrity via disruption of tight junction proteins in cerebrum, cerebellum and hippocampus of female Wistar rats , 2013, Human & experimental toxicology.

[10]  Xueqian Wang,et al.  Functional regulation of P‐glycoprotein at the blood‐brain barrier in proton‐coupled folate transporter (PCFT) mutant mice , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[11]  M. Toborek,et al.  Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signaling. , 2012, Toxicology.

[12]  H. Okuno,et al.  Executive Function Deficits and Social-Behavioral Abnormality in Mice Exposed to a Low Dose of Dioxin In Utero and via Lactation , 2012, PloS one.

[13]  Zu-pei Chen,et al.  Developmental thyroid hormone disruption: prevalence, environmental contaminants and neurodevelopmental consequences. , 2012, Neurotoxicology.

[14]  Y. Ishii,et al.  Dioxin Silences Gonadotropin Expression in Perinatal Pups by Inducing Histone Deacetylases , 2012, The Journal of Biological Chemistry.

[15]  T. Kanda,et al.  Pericyte-derived Glial Cell Line-derived Neurotrophic Factor Increase the Expression of Claudin-5 in the Blood–brain Barrier and the Blood-nerve Barrier , 2012, Neurochemical Research.

[16]  F. Charron,et al.  The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence , 2011, Science.

[17]  Xueqian Wang,et al.  Activating PKC-β1 at the blood—brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[18]  Xueqian Wang,et al.  Aryl hydrocarbon receptor‐mediated up‐regulation of ATP‐driven xenobiotic efflux transporters at the blood‐brain barrier , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  B. Barres,et al.  Pericytes are required for blood–brain barrier integrity during embryogenesis , 2010, Nature.

[20]  M. Kakeyama,et al.  In utero and lactational exposure to low doses of chlorinated and brominated dioxins induces deficits in the fear memory of male mice. , 2010, Neurotoxicology.

[21]  Y. Ishii,et al.  Distribution of 14C-2,3,7,8-tetrachlorodibenzo-p-dioxin to the brain and peripheral tissues of fetal rats and its comparison with adults. , 2010, The Journal of toxicological sciences.

[22]  M. Toborek,et al.  Polychlorinated Biphenyls Disrupt Blood–Brain Barrier Integrity and Promote Brain Metastasis Formation , 2009, Environmental health perspectives.

[23]  F. Fonnum,et al.  Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants , 2009, Journal of neurochemistry.

[24]  R. Weaver,et al.  Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells. , 2009, Biochemical pharmacology.

[25]  Á. Kittel,et al.  A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes , 2009, Neurochemistry International.

[26]  D. Chuang,et al.  Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons. , 2008, The international journal of neuropsychopharmacology.

[27]  J. López-Barneo,et al.  Absolute requirement of GDNF for adult catecholaminergic neuron survival , 2008, Nature Neuroscience.

[28]  M. Kakeyama,et al.  Learning behavior in rat offspring after in utero and lactational exposure to either TCDD or PCB126 , 2008, Environmental health and preventive medicine.

[29]  M. Toborek,et al.  Pcbs and tight junction expression. , 2008, Environmental toxicology and pharmacology.

[30]  B. Zlokovic.  The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders , 2008, Neuron.

[31]  K. Hayashi,et al.  Pericytes from Brain Microvessels Strengthen the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells , 2007, Cellular and Molecular Neurobiology.

[32]  T. Terasaki,et al.  Contribution of Carrier-Mediated Transport Systems to the Blood–Brain Barrier as a Supporting and Protecting Interface for the Brain; Importance for CNS Drug Discovery and Development , 2007, Pharmaceutical Research.

[33]  L. Niles,et al.  Novel targets for valproic acid: up‐regulation of melatonin receptors and neurotrophic factors in C6 glioma cells , 2005, Journal of neurochemistry.

[34]  J. Gee,et al.  Astrocytes: regulation of brain homeostasis via apolipoprotein E. , 2005, The international journal of biochemistry & cell biology.

[35]  B. Zlokovic,et al.  Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes. , 2004, Neurotoxicology.

[36]  J. Jacobson,et al.  Association of Prenatal Exposure to an Environmental Contaminant with Intellectual Function in Childhood , 2002, Journal of toxicology. Clinical toxicology.

[37]  M. Kakeyama,et al.  Changes in expression of NMDA receptor subunit mRNA by perinatal exposure to dioxin , 2001, Neuroreport.

[38]  M. DeVito,et al.  Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing long-evans rats following subchronic exposure. , 2000, Toxicological sciences : an official journal of the Society of Toxicology.

[39]  P G Mulder,et al.  Effects of environmental exposure to polychlorinated biphenyls and dioxins on cognitive abilities in Dutch children at 42 months of age. , 1999, The Journal of pediatrics.

[40]  J. Jacobson,et al.  Intellectual impairment in children exposed to polychlorinated biphenyls in utero. , 1996, The New England journal of medicine.

[41]  R. Vandlen,et al.  Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain , 1995, Nature.

[42]  L. Olson,et al.  Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo , 1995, Nature.

[43]  J. Lile,et al.  GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. , 1993, Science.