Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
暂无分享,去创建一个
William J. Astle | Georg Schett | Damjan Vukcevic | Chris Wallace | Stephen Leslie | Maria C Cid | Mark A Little | James Liley | Tao Jiang | Kenneth G. C. Smith | Vladimir Tesar | Iva Gunnarsson | Barbara Rewerska | Chiara Baldini | Richard A Watts | Paul A Lyons | Kenneth G C Smith | C. Wallace | Damjan Vukcevic | S. Leslie | R. Coulson | P. Lyons | V. Tesar | J. Peters | T. Jiang | A. Vaglio | F. Moosig | I. Gunnarsson | G. Schett | J. Epplen | W. Szczeklik | H. Elding | C. Baldini | G. Emmi | D. Jayne | G. Ramirez | R. Sinico | L. Guillevin | P. Lamprecht | B. Terrier | J. Holle | R. Watts | M. Cid | M. Little | D. Martorana | T. Neumann | S. Ohlsson | David R W Jayne | J. Liley | Loïc Guillevin | Davide Martorana | Thomas Neumann | Sophie Ohlsson | Augusto Vaglio | Wojciech Szczeklik | James E Peters | Federico Alberici | Richard M R Coulson | William Astle | Francesco Bonatti | Heather Elding | Giacomo Emmi | Jörg Epplen | Peter Lamprecht | Frank Moosig | Stefanie Quickert | Giuseppe A Ramirez | Renato A Sinico | Benjamin Terrier | Julia U Holle | F. Bonatti | F. Alberici | S. Quickert | B. Rewerska | W. Astle | T. Jiang
[1] J. Corren,et al. Tezepelumab in Adults with Uncontrolled Asthma. , 2019, The New England journal of medicine.
[2] S. Yancey,et al. Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis , 2017, The New England journal of medicine.
[3] Cisca Wijmenga,et al. The MHC locus and genetic susceptibility to autoimmune and infectious diseases , 2017, Genome Biology.
[4] P. Donnelly,et al. Practical Use of Methods for Imputation of HLA Alleles from SNP Genotype Data , 2016, bioRxiv.
[5] Szilard Voros,et al. Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes. , 2016, The New England journal of medicine.
[6] Jonathan M. Cairns,et al. Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters , 2016, Cell.
[7] William J. Astle,et al. Allelic Landscape of Human Blood Cell Trait Variation and Links , 2016 .
[8] J. Rinn,et al. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan , 2016, Nature.
[9] Stephen Burgess,et al. PhenoScanner: a database of human genotype–phenotype associations , 2016, Bioinform..
[10] Tim J. Carver,et al. CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets , 2016, Bioinform..
[11] David L. Vaux,et al. Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies , 2016, Nature Reviews Cancer.
[12] N. Hanania,et al. Role of T2 inflammation biomarkers in severe asthma , 2016, Current opinion in pulmonary medicine.
[13] P. Merkel,et al. Rituximab for the treatment of eosinophilic granulomatosis with polyangiitis (Churg–Strauss) , 2014, Annals of the rheumatic diseases.
[14] Judy H. Cho,et al. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations , 2015, Nature Genetics.
[15] J. Denburg,et al. Thymic stromal lymphopoietin (TSLP) secretion from human nasal epithelium is a function of TSLP genotype , 2014, Mucosal Immunology.
[16] A. Scott,et al. Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease , 2015, Disease Models & Mechanisms.
[17] Philip A. Ewels,et al. Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C , 2015, Nature Genetics.
[18] G. Kempermann. Faculty Opinions recommendation of Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. , 2015 .
[19] Jun S. Liu,et al. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans , 2015, Science.
[20] N. Wray,et al. Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance components analysis , 2015, Nature Genetics.
[21] G. Sobue,et al. [Central nervous system vasculitis according to the 2012 revise international Chapel Hill consensus conference nomenclature of vasculitides]. , 2015, Brain and nerve = Shinkei kenkyu no shinpo.
[22] Chris Wallace,et al. A Pleiotropy-Informed Bayesian False Discovery Rate Adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics , 2015, bioRxiv.
[23] Carson C Chow,et al. Second-generation PLINK: rising to the challenge of larger and richer datasets , 2014, GigaScience.
[24] B. Berger,et al. Efficient Bayesian mixed model analysis increases association power in large cohorts , 2014, Nature Genetics.
[25] M. Daly,et al. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies , 2014, Nature Genetics.
[26] Super-enhancers delineate disease-associated regulatory nodes in T cells , 2015 .
[27] A. McKenzie. Type-2 innate lymphoid cells in asthma and allergy. , 2014, Annals of the American Thoracic Society.
[28] A. Bredenoord,et al. GWAS identifies four novel eosinophilic esophagitis loci , 2014, Nature Communications.
[29] Ian D Pavord,et al. Mepolizumab treatment in patients with severe eosinophilic asthma. , 2014, The New England journal of medicine.
[30] P. Visscher,et al. Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data. , 2014, Human molecular genetics.
[31] R. Uehara,et al. A nationwide survey on the epidemiology and clinical features of eosinophilic granulomatosis with polyangiitis (Churg-Strauss) in Japan , 2014, Modern rheumatology.
[32] Andrew M. Rupert,et al. Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease , 2014, Nature Genetics.
[33] Manuel A. R. Ferreira,et al. Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. , 2014, The Journal of allergy and clinical immunology.
[34] J. Svaren,et al. Bach2 Regulates Homeostasis of Foxp3+ Regulatory T Cells and Protects against Fatal Lung Disease in Mice , 2014, The Journal of Immunology.
[35] A. Vaglio,et al. Eosinophilic granulomatosis with polyangiitis (Churg–Strauss): evolutions in classification, etiopathogenesis, assessment and management , 2014, Current opinion in rheumatology.
[36] Kari Stefansson,et al. Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization , 2013, Nature Genetics.
[37] Chuong B. Do,et al. A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci , 2013, Nature Genetics.
[38] L. Mouthon,et al. Antineutrophil cytoplasmic antibody-associated vasculitides: is it time to split up the group? , 2013, Annals of the rheumatic diseases.
[39] D. Rujescu,et al. Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate , 2013, PLoS genetics.
[40] Satoru Takahashi,et al. Transcription Factors GATA-3 and RORγt Are Important for Determining the Phenotype of Allergic Airway Inflammation in a Murine Model of Asthma , 2013, The Journal of Immunology.
[41] P. Merkel,et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. , 2013, Arthritis and rheumatism.
[42] L. Mouthon,et al. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohort. , 2013, Arthritis and rheumatism.
[43] O. Delaneau,et al. Supplementary Information for ‘ Improved whole chromosome phasing for disease and population genetic studies ’ , 2012 .
[44] Jake K. Byrnes,et al. Bayesian refinement of association signals for 14 loci in 3 common diseases , 2012, Nature Genetics.
[45] P. Khoury,et al. Serum biomarkers are similar in Churg–Strauss syndrome and hypereosinophilic syndrome , 2012, Allergy.
[46] J. Marchini,et al. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing , 2012, Nature Genetics.
[47] Panos Deloukas,et al. Genetically distinct subsets within ANCA-associated vasculitis. , 2012, The New England journal of medicine.
[48] David J Balding,et al. A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. , 2011, The Journal of allergy and clinical immunology.
[49] Florence Demenais,et al. A large-scale, consortium-based genomewide association study of asthma. , 2010, The New England journal of medicine.
[50] G. Nilsson,et al. The BH3-Mimetic ABT-737 Induces Mast Cell Apoptosis In Vitro and In Vivo: Potential for Therapeutics , 2010, The Journal of Immunology.
[51] P. van Paassen,et al. Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis. , 2010, The New England journal of medicine.
[52] D. Huang,et al. BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs , 2010, Proceedings of the National Academy of Sciences.
[53] Joseph T. Glessner,et al. Common variants at 5q22 associate with pediatric eosinophilic esophagitis , 2010, Nature Genetics.
[54] Saskia M Pasedag,et al. Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP. , 2009, Translational oncology.
[55] P. Donnelly,et al. A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies , 2009, PLoS genetics.
[56] D. Postma,et al. Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction , 2009, Nature Genetics.
[57] S. Pai,et al. GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation , 2009, Nature Reviews Immunology.
[58] Jon Wakefield,et al. Bayes factors for genome‐wide association studies: comparison with P‐values , 2009, Genetic epidemiology.
[59] Takahiko Sugihara,et al. Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors1 , 2008, The Journal of Immunology.
[60] J. Epplen,et al. Associations of Churg-Strauss syndrome with the HLA-DRB1 locus, and relationship to the genetics of antineutrophil cytoplasmic antibody-associated vasculitides: comment on the article by Vaglio et al. , 2008, Arthritis and rheumatism.
[61] U. Maggiore,et al. HLA-DRB4 as a genetic risk factor for Churg-Strauss syndrome. , 2007, Arthritis and rheumatism.
[62] Tetsuo Noda,et al. Plasmacytic Transcription Factor Blimp-1 Is Repressed by Bach2 in B Cells* , 2006, Journal of Biological Chemistry.
[63] G. Besra,et al. GATA-3 Regulates the Development and Function of Invariant NKT Cells1 , 2006, The Journal of Immunology.
[64] L. Mouthon,et al. Antineutrophil Cytoplasmic Antibodies and the ChurgStrauss Syndrome , 2005, Annals of Internal Medicine.
[65] Laura Pavone,et al. Prevalence and clinical significance of antineutrophil cytoplasmic antibodies in Churg-Strauss syndrome. , 2005, Arthritis and rheumatism.
[66] G. Nilsson,et al. Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation , 2005, Cell Death and Differentiation.
[67] Booki Min,et al. Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses , 2004, Nature Immunology.
[68] J. Lötvall,et al. Regulation of bone marrow and airway CD34+ eosinophils by interleukin-5. , 2004, American journal of respiratory cell and molecular biology.
[69] S. Pai,et al. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[70] A. Strasser,et al. Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells , 2003, The Journal of experimental medicine.
[71] A. Strasser,et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes , 2002, Nature.
[72] A. Strasser,et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. , 1999, Science.
[73] N. Day,et al. EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer. , 1999, British journal of cancer.
[74] T. Pincus,et al. Limitations of the 1990 American College of Rheumatology Classification Criteria in the Diagnosis of Vasculitis , 1998, Annals of Internal Medicine.
[75] D. Scott,et al. Churg-Strauss syndrome in a district hospital. , 1998, QJM : monthly journal of the Association of Physicians.
[76] Richard A Flavell,et al. The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells , 1997, Cell.
[77] L. Staudt,et al. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. , 1997, Science.
[78] R. Matsumura,et al. IL‐5 but not interferon‐gamma (IFN‐γ) inhibits eosinophil apoptosis by up‐regulation of bcl‐2 expression , 1997, Clinical and experimental immunology.
[79] J. Leiden,et al. Transcription factor GATA-3 is required for development of the T-cell lineage , 1996, Nature.
[80] A. Wardlaw,et al. Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. , 1992, Blood.
[81] D A Bloch,et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). , 2010, Arthritis and rheumatism.
[82] G. Hughes,et al. Systemic Vasculitis with Asthma and Eosinophilia: A Clinical Approach to the Churg‐Strauss Syndrome , 1984, Medicine.
[83] J. Churg,et al. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. , 1951, The American journal of pathology.