Comparison of induction and recovery between sevoflurane and halothane supplementation of anaesthesia in children undergoing outpatient dental extractions.

We have compared sevoflurane and halothane in a double-blind controlled study for supplementation of nitrous oxide and oxygen anaesthesia in 80 children undergoing dental extraction as outpatients. Induction of anaesthesia was more rapid in those who received sevoflurane compared with those who received halothane (89 s compared with 127 s for loss of eyelash reflex). In both groups, mean duration of administration of anaesthesia was less than 4 min. Those who received sevoflurane were slower to awaken (167 s compared with 102 s), although discharge times from hospital were similar. The incidence of complications during induction and maintenance was low in both groups and return to normal appetite and activity occurred in the majority of children on the same day. More children who received halothane suffered nausea after leaving hospital. We conclude that sevoflurane is a suitable alternative to halothane, with more rapid induction of anaesthesia, but in these short procedures, awakening time was slower than after halothane.

[1]  A. Mackersie,et al.  A comparison of the recovery characteristics of sevoflurane and halothane in children , 1996, Anaesthesia.

[2]  T. Taivainen,et al.  Sevoflurane-nitrous oxide or halothane-nitrous oxide for paediatric bronchoscopy and gastroscopy. , 1996, British journal of anaesthesia.

[3]  A. Mackersie,et al.  A comparison of the induction characteristics of sevoflurane and halothane in children , 1996, Anaesthesia.

[4]  G. Johannesson,et al.  Sevoflurane for ENT‐surgery in children A comparison with halothane , 1995, Acta anaesthesiologica Scandinavica.

[5]  H. Kimura,et al.  A comparison of vital capacity breath and tidal breathing techniques for induction of anaesthesia with high sevoflurane concentrations in nitrous oxide and oxygen , 1995, Anaesthesia.

[6]  J. Lerman,et al.  Clinical Characteristics of Sevoflurane in Children: A Comparison with Halothane , 1995, Anesthesiology.

[7]  T. Taivainen,et al.  Comparison of the effects of sevoflurane and halothane on the quality of anaesthesia and serum glutathione transferase alpha and fluoride in paediatric patients. , 1994, British journal of anaesthesia.

[8]  I. Murat,et al.  Induction and recovery characteristics and hemodynamic responses to sevoflurane and halothane in children. , 1994, Anesthesia and analgesia.

[9]  J. Lerman,et al.  The Pharmacology of Sevoflurane in Infants and Children , 1994, Anesthesiology.

[10]  K. Shingu,et al.  Comparison between sevoflurane and halothane for paediatric ambulatory anaesthesia. , 1991, British journal of anaesthesia.

[11]  R. Weiskopf,et al.  Comparison of Kinetics of Sevoflurane and Isoflurane in Humans , 1991, Anesthesia and analgesia.

[12]  E. Eger,et al.  Partition coefficients for sevoflurane in human blood, saline, and olive oil. , 1987, Anesthesia and analgesia.

[13]  G. Cooper,et al.  COMPARISON OF ISOFLURANE AND HALOTHANE IN OUTPATIENT PAEDIATRIC DENTAL ANAESTHESIA , 1986 .

[14]  E. Eger,et al.  The Relationship between Age and Halothane Requirement in Man , 1969, Anesthesiology.