Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles

[1]  K. Hilligan,et al.  Antigen presentation by dendritic cells and their instruction of CD4+ T helper cell responses , 2020, Cellular & Molecular Immunology.

[2]  Johannes U. Mayer,et al.  Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection , 2020, Immunity.

[3]  F. Lund,et al.  Compartmentalization of dendritic cell and T‐cell interactions in the lymph node: Anatomy of T‐cell fate decisions , 2019, Immunological reviews.

[4]  Chun Jimmie Ye,et al.  Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity , 2019, Cell.

[5]  Johannes U. Mayer,et al.  Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity. , 2019, Cell systems.

[6]  M. Merad,et al.  PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs , 2018, Nature Communications.

[7]  S. Eisenbarth.  Dendritic cell subsets in T cell programming: location dictates function , 2018, Nature Reviews Immunology.

[8]  H. Hammad,et al.  Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4–dependent dermal dendritic cells , 2017, The Journal of allergy and clinical immunology.

[9]  Johannes U. Mayer,et al.  Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon , 2017, Nature Communications.

[10]  Miranda R Lyons-Cohen,et al.  Distinct functions of CXCR4, CCR2, and CX3CR1 direct dendritic cell precursors from the bone marrow to the lung , 2017, Journal of leukocyte biology.

[11]  Neil D. Lawrence,et al.  Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria , 2017, Science Immunology.

[12]  A. Lew,et al.  Heterogeneity, functional specialization and differentiation of monocyte‐derived dendritic cells , 2017, Immunology and cell biology.

[13]  David A. Eccles,et al.  Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles , 2017, The Journal of experimental medicine.

[14]  K. Murphy,et al.  Functions of Murine Dendritic Cells. , 2016, Immunity.

[15]  N. McGovern,et al.  Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species , 2016, Immunity.

[16]  A. Lew,et al.  Monocyte-Derived Dendritic Cells Promote Th Polarization, whereas Conventional Dendritic Cells Promote Th Proliferation , 2016, The Journal of Immunology.

[17]  F. Ronchese,et al.  Monocyte-Derived Dendritic Cells Are Essential for CD8+ T Cell Activation and Antitumor Responses After Local Immunotherapy , 2015, Front. Immunol..

[18]  T. Rülicke,et al.  Antigen-Specific Th17 Cells Are Primed by Distinct and Complementary Dendritic Cell Subsets in Oropharyngeal Candidiasis , 2015, PLoS pathogens.

[19]  Allyson L. Byrd,et al.  Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory Function during Infection. , 2015, Immunity.

[20]  Xiaodi Wu,et al.  Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses. , 2015, Immunity.

[21]  Michael Y. Gerner,et al.  Strategically localized dendritic cells promote rapid T cell responses to lymph-borne particulate antigens. , 2015, Immunity.

[22]  F. Ronchese,et al.  Helminth-Conditioned Dendritic Cells Prime CD4+ T Cells to IL-4 Production In Vivo , 2014, The Journal of Immunology.

[23]  W. Weninger,et al.  CD326loCD103loCD11blo Dermal Dendritic Cells Are Activated by Thymic Stromal Lymphopoietin during Contact Sensitization in Mice , 2014, The Journal of Immunology.

[24]  F. Klauschen,et al.  T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo. , 2014, Immunity.

[25]  H. A. Schreiber,et al.  Essential yet limited role for CCR2+ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming , 2013, eLife.

[26]  Hongyu Zhao,et al.  Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. , 2013, Immunity.

[27]  A. Iwasaki,et al.  CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity. , 2013, Immunity.

[28]  Y. Belkaid,et al.  Evaluating the in vivo Th2 priming potential among common allergens. , 2013, Journal of immunological methods.

[29]  N. McGovern,et al.  IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses , 2013, Immunity.

[30]  S. Gudjonsson,et al.  IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation. , 2013, Immunity.

[31]  Miriam Merad,et al.  The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. , 2013, Annual review of immunology.

[32]  H. Hammad,et al.  Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. , 2013, Immunity.

[33]  S. Turner,et al.  IRF4 Promotes Cutaneous Dendritic Cell Migration to Lymph Nodes during Homeostasis and Inflammation , 2012, The Journal of Immunology.

[34]  I. Visan.  Location dictates function , 2012, Nature Immunology.

[35]  Charles C. Kim,et al.  Molecular definition of the identity and activation of natural killer cells , 2012, Nature Immunology.

[36]  Charles C. Kim,et al.  ImmGen Report: Molecular definition of Natural Killer cell identity and activation , 2013 .

[37]  A. Sher,et al.  NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection. , 2012, Immunity.

[38]  S. Ziegler,et al.  Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling. , 2012, The Journal of allergy and clinical immunology.

[39]  W. Paul,et al.  Peripheral CD4+ T‐cell differentiation regulated by networks of cytokines and transcription factors , 2010, Immunological reviews.

[40]  T. Kakiuchi,et al.  Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute TH1 immune responses , 2009, Nature Immunology.

[41]  E. Unanue,et al.  Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity , 2008, Science.

[42]  Yu Wang,et al.  TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand , 2005, The Journal of experimental medicine.

[43]  Michael Loran Dustin.  Faculty Opinions recommendation of Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. , 2005 .

[44]  P. Perrin,et al.  Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. , 2005, Immunity.

[45]  C. Sousa,et al.  Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function , 2005, Nature Immunology.

[46]  A. Iwasaki,et al.  Toll-like receptor control of the adaptive immune responses , 2004, Nature Immunology.

[47]  M. Kapsenberg.  Dendritic-cell control of pathogen-driven T-cell polarization , 2003, Nature Reviews Immunology.

[48]  Xiaojing Ma,et al.  Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1 , 2003, The Journal of experimental medicine.

[49]  G. Trinchieri,et al.  Flexibility of Mouse Classical and Plasmacytoid-derived Dendritic Cells in Directing T Helper Type 1 and 2 Cell Development , 2003, The Journal of experimental medicine.

[50]  C. Sousa,et al.  The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals , 2003, European journal of immunology.

[51]  A. Sher,et al.  In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting. , 2002, Immunity.

[52]  A. Sher,et al.  CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. , 2000, Immunity.

[53]  H. Nariuchi,et al.  Effective stimulation for IL-12 p35 mRNA accumulation and bioactive IL-12 production of antigen-presenting cells interacted with Th cells. , 1999, Journal of immunology.

[54]  Robert V Farese,et al.  Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. , 1997, The Journal of clinical investigation.

[55]  S. Szabo,et al.  Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells , 1997, The Journal of experimental medicine.

[56]  C. Janeway,et al.  Monoclonal antibodies specific for Ia glycoproteins raised by immunization with activated T cells: possible role of T cellbound Ia antigens as targets of immunoregulatory T cells. , 1984, Journal of immunology.

[57]  P. Marrack,et al.  Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines. , 1983, Journal of immunology.

[58]  A. Glasebrook,et al.  IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. , 1980, Journal of immunology.

[59]  R. Steinman,et al.  Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[60]  R. Fallon.  RESPIRATORY VIRUS INFECTION , 1965 .

[61]  Jianfei Yang,et al.  T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells , 2002, Nature Immunology.

[62]  G. Chew.  House dust mite allergen. , 1996, American Industrial Hygiene Association journal.