Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways

[1]  Bas Vroling,et al.  GPCRdb: an information system for G protein-coupled receptors , 2016, Nucleic acids research.

[2]  Bas Vroling,et al.  GPCRdb: an information system for G protein-coupled receptors , 2015, Nucleic Acids Res..

[3]  Ling-Qing Yuan,et al.  Leptin promotes the osteoblastic differentiation of vascular smooth muscle cells from female mice by increasing RANKL expression. , 2014, Endocrinology.

[4]  Chao-ke Tang,et al.  Apelin and its receptor APJ in cardiovascular diseases. , 2014, Clinica chimica acta; international journal of clinical chemistry.

[5]  Ling-Qing Yuan,et al.  MiR-133a modulates osteogenic differentiation of vascular smooth muscle cells. , 2013, Endocrinology.

[6]  O. Alfieri,et al.  Guidelines on the management of valvular heart disease. , 2007, European heart journal.

[7]  J. Leopold.  Cellular Mechanisms of Aortic Valve Calcification , 2012, Circulation. Cardiovascular interventions.

[8]  Ling-Qing Yuan,et al.  Taurine suppresses osteoblastic differentiation of aortic valve interstitial cells induced by beta-glycerophosphate disodium, dexamethasone and ascorbic acid via the ERK pathway , 2012, Amino Acids.

[9]  K. J. Grande-Allen,et al.  Calcific Aortic Valve Disease : Not Simply a Degenerative Process A Review and Agenda for Research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group , 2012 .

[10]  D. Towler,et al.  Thematic series on the pathobiology of vascular calcification: an introduction. , 2011, Circulation research.

[11]  Ling-Qing Yuan,et al.  Apelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells , 2011, PloS one.

[12]  H. Xie,et al.  Apelin suppresses apoptosis of human vascular smooth muscle cells via APJ/PI3-K/Akt signaling pathways , 2010, Amino Acids.

[13]  Y. Soini,et al.  Apelin and its receptor APJ in human aortic valve stenosis. , 2009, The Journal of heart valve disease.

[14]  C. Otto,et al.  Calcific aortic stenosis--time to look more closely at the valve. , 2008, The New England journal of medicine.

[15]  T. McDonagh,et al.  The role of apelin in cardiovascular function and heart failure , 2008, European journal of heart failure.

[16]  Yin Tintut,et al.  Vascular calcification: pathobiology of a multifaceted disease. , 2008, Circulation.

[17]  J. Cleveland,et al.  Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis. , 2008, American journal of physiology. Cell physiology.

[18]  Wei Liu,et al.  Taurine inhibits osteoblastic differentiation of vascular smooth muscle cells via the ERK pathway , 2008, Amino Acids.

[19]  M. Yacoub,et al.  Direct effects of apelin on cardiomyocyte contractility and electrophysiology. , 2007, Biochemical and biophysical research communications.

[20]  T. Quertermous.  Apelin and its g protein-coupled receptor regulate cardiac development as well as cardiac function. , 2007, Developmental cell.

[21]  Helmut Baumgartner,et al.  Guidelines on the management of valvular heart disease The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology , 2007 .

[22]  J. Gardin,et al.  Burden of valvular heart diseases: a population-based study , 2006, The Lancet.

[23]  B. O'dowd,et al.  Unravelling the roles of the apelin system: prospective therapeutic applications in heart failure and obesity. , 2006, Trends in pharmacological sciences.

[24]  J. Skepper,et al.  Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells , 2005, Regulatory Peptides.

[25]  A. Davenport,et al.  Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells , 2004, Regulatory Peptides.

[26]  Philippe Ravaud,et al.  A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. , 2003, European heart journal.

[27]  H. Schiöth,et al.  The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. , 2003, Molecular pharmacology.

[28]  A. Tajik,et al.  Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype , 2003, Circulation.

[29]  O. Nishimura,et al.  Molecular properties of apelin: tissue distribution and receptor binding. , 2001, Biochimica et biophysica acta.

[30]  Emile R. Mohler,et al.  Bone Formation and Inflammation in Cardiac Valves , 2001, Circulation.

[31]  S. Hinuma,et al.  Molecular and Functional Characteristics of APJ TISSUE DISTRIBUTION OF mRNA AND INTERACTION WITH THE ENDOGENOUS LIGAND APELIN* , 2000 .

[32]  S. Hinuma,et al.  Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. , 1998, Biochemical and biophysical research communications.

[33]  H. Heng,et al.  A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11. , 1993, Gene.

[34]  P. Öckerman.  Acid hydrolases in skin and plasma in gargoylism. Deficiency of β-galactosidase in skin , 1968 .

[35]  R. Scully,et al.  AGING CHANGES IN THE AORTIC AND MITRAL VALVES. HISTOLOGIC AND HISTOCHEMICAL STUDIES, WITH OBSERVATIONS ON THE PATHOGENESIS OF CALCIFIC AORTIC STENOSIS AND CALCIFICATION OF THE MITRAL ANNULUS. , 1965, The American journal of pathology.