In order to avoid the disadvantages of early PM-OLED driving and controlling circuits such as: the ”cross talk” and ”interference” phenomenon and much complexity, the circuits based on controlling IC LPC22IO and driving IC SSD1339 from Philips Corporation and Solomn Corporation respectively are designed in two ways. Structure and luminescent principle of OLED, SSD1339 and LPC2210 key features are introduced firstly. The two read and write timings of EMC on LPC2210 and 8080-series parallel interface on SSD1339 are compared and analyzed. SSD1339 is controlled to drive the 128RGB×128 dot-matrix OLED panel successfully in two ways by using GPIO and EMC on LPC2210. The experimental results show that both ways can avoid the disadvantages of early driving and controlling circuits effectively, and make the panel display with good quality pictures. Using EMC, it is able to transmit about 80 pieces of picture in a second. Using GPIO, every steps of the data transmission can be tracked; therefore, it's convenient to find the hidden mistakes. The experiment provides guidelines for designing PM-OLED driving and controlling circuits in different integrated situations