Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases
暂无分享,去创建一个
Piero Carninci | Y. Hayashizaki | T. Lassmann | A. Forrest | S. Gustincich | M. Itoh | H. Kawaji | P. Heutink | S. Zucchelli | F. Persichetti | P. Rizzu | Stefania Fedele | C. Santoro | R. Calligaris | P. Vatta
[1] T. Dawson,et al. Trumping neurodegeneration: Targeting common pathways regulated by autosomal recessive Parkinson's disease genes , 2017, Experimental Neurology.
[2] Xuetao Cao,et al. An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism , 2017, Science.
[3] Karen S. Frese,et al. Genomic structural variations lead to dysregulation of important coding and non‐coding RNA species in dilated cardiomyopathy , 2017, EMBO molecular medicine.
[4] S. Gustincich,et al. The Yin and Yang of nucleic acid-based therapy in the brain , 2017, Progress in Neurobiology.
[5] Jordan A. Ramilowski,et al. An atlas of human long non-coding RNAs with accurate 5′ ends , 2017, Nature.
[6] B. Mandefro,et al. Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy , 2017, Proceedings of the National Academy of Sciences.
[7] Simon C. Potter,et al. Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing , 2017, Genome Biology.
[8] L. Rubin,et al. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy , 2017, Neuron.
[9] G. Schellenberg,et al. Genomic variants, genes, and pathways of Alzheimer's disease: An overview , 2017, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[10] T. Derrien,et al. A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies , 2016, PLoS genetics.
[11] T. Lynch,et al. Genetics of Frontotemporal Dementia , 2016, Current Neurology and Neuroscience Reports.
[12] J. Rinn,et al. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan , 2016, Nature.
[13] D. Hernandez,et al. Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe , 2016, Genome Medicine.
[14] S. Gustincich,et al. Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo , 2016, Scientific Reports.
[15] Ekaterina Nosova,et al. α‐synuclein genetic variability: A biomarker for dementia in Parkinson disease , 2016, Annals of neurology.
[16] David S. Wishart,et al. Heatmapper: web-enabled heat mapping for all , 2016, Nucleic Acids Res..
[17] C. Blauwendraat,et al. C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers , 2016, Acta Neuropathologica Communications.
[18] D. Underhill,et al. C9orf72 is required for proper macrophage and microglial function in mice , 2016, Science.
[19] Simon C. Potter,et al. Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy. , 2016, American journal of human genetics.
[20] C. Wahlestedt,et al. Transcriptomic Profiling of Extracellular RNAs Present in Cerebrospinal Fluid Identifies Differentially Expressed Transcripts in Parkinson’s Disease , 2016, Journal of Parkinson's disease.
[21] H. Soreq,et al. Transcriptome profiling in Parkinson's leukocytes: from early diagnostics to neuroimmune therapeutic prospects. , 2016, Current opinion in pharmacology.
[22] Xiaolin Zhou,et al. Identification of Alzheimer's disease–associated long noncoding RNAs , 2015, Neurobiology of Aging.
[23] D. di Bernardo,et al. Blood transcriptomics of drug-naïve sporadic Parkinson’s disease patients , 2015, BMC Genomics.
[24] Keith A. Johnson,et al. Modulation of TREM2 by CD33: a protein QTL study integrates Alzheimer loci in human monocytes , 2015, Nature neuroscience.
[25] Piero Carninci,et al. SINEUPs: A new class of natural and synthetic antisense long non-coding RNAs that activate translation , 2015, RNA biology.
[26] O. Khorkova,et al. Basic biology and therapeutic implications of lncRNA. , 2015, Advanced drug delivery reviews.
[27] Piero Carninci,et al. SINEUPs are modular antisense long non-coding RNAs that increase synthesis of target proteins in cells , 2015, Front. Cell. Neurosci..
[28] R. F. Luco,et al. A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature , 2015, Nature Structural &Molecular Biology.
[29] Thomas J. Ha,et al. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells , 2015, Science.
[30] D. Holtzman,et al. TREM2 lipid sensing sustains microglia response in an Alzheimer’s disease model , 2015, Cell.
[31] S. Dhanasekaran,et al. The landscape of long noncoding RNAs in the human transcriptome , 2015, Nature Genetics.
[32] Derek W Wright,et al. Gateways to the FANTOM5 promoter level mammalian expression atlas , 2015, Genome Biology.
[33] André L. Martins,et al. Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers , 2014, Nature Genetics.
[34] Marcel E. Dinger,et al. lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs , 2014, Nucleic Acids Res..
[35] Leighton J. Core,et al. Nuclear stability and transcriptional directionality separate functionally distinct RNA species , 2014, Nature Communications.
[36] W. M. van der Flier,et al. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies , 2014, Human molecular genetics.
[37] T. Meehan,et al. An atlas of active enhancers across human cell types and tissues , 2014, Nature.
[38] Cesare Furlanello,et al. A promoter-level mammalian expression atlas , 2015 .
[39] Yoshihide Hayashizaki,et al. Interactive visualization and analysis of large-scale sequencing datasets using ZENBU , 2014, Nature Biotechnology.
[40] Hagai Bergman,et al. Long Non-Coding RNA and Alternative Splicing Modulations in Parkinson's Leukocytes Identified by RNA Sequencing , 2014, PLoS Comput. Biol..
[41] David R. Kelley,et al. Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre , 2014, Nature Structural &Molecular Biology.
[42] David R. Kelley,et al. Topological Organization of Multi-chromosomal Regions by Firre , 2014, Nature structural & molecular biology.
[43] Claes Wahlestedt,et al. Targeting long non-coding RNA to therapeutically upregulate gene expression. , 2013, Nature Reviews Drug Discovery.
[44] J. Rothstein,et al. RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia , 2013, Proceedings of the National Academy of Sciences.
[45] Bradley T. Hyman,et al. Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta , 2013, Neuron.
[46] L. Tran,et al. Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease , 2013, Cell.
[47] E. Kremmer,et al. The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS , 2013, Science.
[48] T. Hirose,et al. Paraspeckle formation during the biogenesis of long non-coding RNAs , 2013, RNA biology.
[49] B. Becher,et al. Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline , 2012, Nature Medicine.
[50] Piero Carninci,et al. Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat , 2012, Nature.
[51] David G. Knowles,et al. The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression , 2012, Genome research.
[52] Bronwen L. Aken,et al. GENCODE: The reference human genome annotation for The ENCODE Project , 2012, Genome research.
[53] Beatrice Bodega,et al. A Long ncRNA Links Copy Number Variation to a Polycomb/Trithorax Epigenetic Switch in FSHD Muscular Dystrophy , 2012, Cell.
[54] C. Wahlestedt,et al. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation , 2012, Nature Biotechnology.
[55] C. Wahlestedt,et al. Natural Antisense Inhibition Results in Transcriptional De-Repression and Gene Upregulation , 2012, Nature biotechnology.
[56] D. Cacchiarelli,et al. A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA , 2011, Cell.
[57] D. Geschwind,et al. Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS , 2011, Neuron.
[58] David Heckerman,et al. A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD , 2011, Neuron.
[59] Ferdinando Di Cunto,et al. Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs , 2011, Cell.
[60] R. Margolis,et al. A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression. , 2011, Human molecular genetics.
[61] Marc N. Offman,et al. A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. , 2011, American journal of human genetics.
[62] M. Farrer,et al. VPS35 mutations in Parkinson disease. , 2011, American journal of human genetics.
[63] S. Sunkin,et al. CTCF Regulates Ataxin-7 Expression through Promotion of a Convergently Transcribed, Antisense Noncoding RNA , 2011, Neuron.
[64] Howard Y. Chang,et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression , 2011, Nature.
[65] D. G. Clark,et al. Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease , 2011, Nature Genetics.
[66] Nick C Fox,et al. Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease , 2011, Nature Genetics.
[67] K. Dujardin,et al. SNCA locus duplication carriers: from genetics to Parkinson disease phenotypes , 2011, Human mutation.
[68] L. Maquat,et al. lncRNAs transactivate Staufen1-mediated mRNA decay by duplexing with 3'UTRs via Alu elements , 2010, Nature.
[69] T. Derrien,et al. Long Noncoding RNAs with Enhancer-like Function in Human Cells , 2010, Cell.
[70] B. Blencowe,et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. , 2010, Molecular cell.
[71] J. Rinn,et al. A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response , 2010, Cell.
[72] M. Nalls,et al. Evidence for natural antisense transcript-mediated inhibition of microRNA function , 2010, Genome Biology.
[73] A. Mallamaci,et al. Regulation of Emx2 Expression by Antisense Transcripts in Murine Cortico-Cerebral Precursors , 2010, PloS one.
[74] Martin S. Taylor,et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line , 2009, Nature Genetics.
[75] John N. Hutchinson,et al. An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. , 2009, Molecular cell.
[76] F. Rosenbauer,et al. PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element. , 2008, Genes & development.
[77] T. Morgan,et al. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase , 2008, Nature Medicine.
[78] A. G. de Herreros,et al. A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. , 2008, Genes & development.
[79] A. Feinberg,et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA , 2008, Nature.
[80] S. Tapscott,et al. An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals. , 2007, Human molecular genetics.
[81] P. Lockhart,et al. Parkin Co-regulated Gene (PACRG) is regulated by the ubiquitin–proteasomal system and is present in the pathological features of parkinsonian diseases , 2007, Neurobiology of Disease.
[82] Howard Y. Chang,et al. Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs , 2007, Cell.
[83] T. Lassmann,et al. The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function , 2007, BMC Genomics.
[84] Martin S. Taylor,et al. Genome-wide analysis of mammalian promoter architecture and evolution , 2006, Nature Genetics.
[85] Sin Lam Tan,et al. Complex Loci in Human and Mouse Genomes , 2006, PLoS genetics.
[86] S. Batalov,et al. Antisense Transcription in the Mammalian Transcriptome , 2005, Science.
[87] Janel O. Johnson,et al. α-Synuclein Locus Triplication Causes Parkinson's Disease , 2003, Science.
[88] D. Higgs,et al. Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease , 2003, Nature Genetics.
[89] M. Lazar,et al. Post-transcriptional Regulation of Thyroid Hormone Receptor Expression by cis-Acting Sequences and a Naturally Occurring Antisense RNA* , 2000, The Journal of Biological Chemistry.
[90] V. Bonifati. Genetics of Parkinson's disease--state of the art, 2013. , 2014, Parkinsonism & related disorders.
[91] Xiaoqiu Huang,et al. Over 20% of human transcripts might form sense-antisense pairs. , 2004, Nucleic acids research.
[92] A. Singleton,et al. alpha-Synuclein locus triplication causes Parkinson's disease. , 2003, Science.
[93] Piero Carninci,et al. Unamplified Cap Analysis of Gene Expression on a Single-molecule Sequencer , 2022 .