Thin-Film Magnetoelastic Microsensors for Remote Query Biomedical Monitoring

Magnetoelastic thin-film sensors can be considered the magnetic analog of an acoustic bell: in response to an externally applied magnetic field impulse the sensors ring like a bell, emitting magnetic flux with a characteristic resonant frequency. The magnetic flux can be detected remotely, external to the test area, using a pick-up coil. By monitoring changes in the characteristic resonant frequency of the sensor multiple environmental parameters can be measured. In this work we report on application of magnetoelastic sensors for remote query measurement of temperature, pressure, viscosity and, in combination with a glucose-responding mass-changing polymer, in situ measurement of biological-level glucose concentrations. The advantage of using magnetoelastic sensors is that they are monitored remotely, without the need for direct physical connections such as wires or cables, nor line-of-sight alignment as needed with optical detection methods. The remote query capability allows the magnetoelastic sensors to be monitored from inside sealed, opaque containers. Depending upon the application magnetoelastic sensors can be sized from micrometer to millimeter dimensional scales, and have a material cost of approximately $0.001 allowing for their use on a disposable basis.

[1]  S. Timoshenko,et al.  Theory of elasticity , 1975 .

[2]  R. C. Weast CRC Handbook of Chemistry and Physics , 1973 .

[3]  P. M. Anderson Magnetomechanical coupling, ΔE effect, and permeability in FeSiB and FeNiMoB alloys , 1982 .

[4]  J. Gordon,et al.  The oscillation frequency of a quartz resonator in contact with liquid , 1985 .

[5]  C. L. Arthur,et al.  Liquid-phase piezoelectric and acoustic transmission studies of interfacial immunochemistry. , 1986, Analytical chemistry.

[6]  S. Yao,et al.  Dependence of the oscillation frequency of a piezoelectric crystal on the physical parameters of liquids , 1988 .

[7]  Rolf Schumacher,et al.  The Quartz Microbalance: A Novel Approach to the In‐Situ Investigation of Interfacial Phenomena at the Solid/Liquid Junction [New Analytical Methods (40)] , 1990 .

[8]  Theory and application of a quartz resonator as a sensor for viscous liquids , 1990 .

[9]  Leland B. Jackson Signals, systems, and transforms , 1991 .

[10]  W. Seitz,et al.  A fiber optic sensor for water in organic solvents based on polymer swelling. , 1994, Talanta.

[11]  H Hoshino,et al.  Glucose-sensing electrode coated with polymer complex gel containing phenylboronic Acid. , 1996, Analytical chemistry.

[12]  W. Seitz,et al.  A Remotely Interrogatable Magnetochemical pH Sensor , 1997, 1997 IEEE International Magnetics Conference (INTERMAG'97).

[13]  N. Soga,et al.  Young's modulus of RF-sputtered amorphous thin films in the SiO2-Y2O3 system at high temperature , 1997 .

[14]  W. Seitz,et al.  A remotely interrogatable sensor for chemical monitoring. , 1998, IEEE transactions on magnetics.

[15]  K G Ong,et al.  A magnetostatic-coupling based remote query sensor for environmental monitoring. , 1999, Journal of physics D: Applied physics.