A Statistical Skull Geometry Model for Children 0-3 Years Old

Head injury is the leading cause of fatality and long-term disability for children. Pediatric heads change rapidly in both size and shape during growth, especially for children under 3 years old (YO). To accurately assess the head injury risks for children, it is necessary to understand the geometry of the pediatric head and how morphologic features influence injury causation within the 0–3 YO population. In this study, head CT scans from fifty-six 0–3 YO children were used to develop a statistical model of pediatric skull geometry. Geometric features important for injury prediction, including skull size and shape, skull thickness and suture width, along with their variations among the sample population, were quantified through a series of image and statistical analyses. The size and shape of the pediatric skull change significantly with age and head circumference. The skull thickness and suture width vary with age, head circumference and location, which will have important effects on skull stiffness and injury prediction. The statistical geometry model developed in this study can provide a geometrical basis for future development of child anthropomorphic test devices and pediatric head finite element models.

[1]  D F Huelke,et al.  Infants and children in the adult world of automobile safety design: pediatric and anatomical considerations for design of child restraints. , 1969, Journal of biomechanics.

[2]  J. Mcelhaney,et al.  Mechanical properties on cranial bone. , 1970, Journal of biomechanics.

[3]  R. Hubbard,et al.  Flexure of layered cranial bone. , 1971, Journal of biomechanics.

[4]  C. L. Owings,et al.  Infant, Child and teenager Anthropometry For Product Safety Design , 1978 .

[5]  G. Livshits Growth and development of bodyweight, height and head circumference during the first two years of life: quantitative genetic aspects. , 1986, Annals of human biology.

[6]  D Mukherjee,et al.  Head circumference reference data: birth to 18 years. , 1987, Pediatrics.

[7]  F. Netter Atlas of Human Anatomy , 1967 .

[8]  J. G. Rodríguez Childhood injuries in the United States. A priority issue. , 1990, American journal of diseases of children.

[9]  P Hemyari,et al.  Brain injuries among infants, children, adolescents, and young adults. , 1990, American journal of diseases of children.

[10]  H von Holst,et al.  Serious brain injury from traffic-related causes: priorities for primary prevention. , 1997, Accident; analysis and prevention.

[11]  Harold J. Mertz,et al.  Biomechanical basis for the CRABI and Hybrid III child dummies , 1997 .

[12]  Harold J. Mertz,et al.  INJURY RISK CURVES FOR CHILDREN AND ADULTS IN FRONTAL AND REAR COLLISIONS , 1997 .

[13]  S D Guerra,et al.  Pediatric head injury , 2005 .

[14]  R W Prager,et al.  Fetal head moulding: finite element analysis of a fetal skull subjected to uterine pressures during the first stage of labour. , 2001, Journal of biomechanics.

[15]  A. King,et al.  Comparison of brain responses between frontal and lateral impacts by finite element modeling. , 2001, Journal of neurotrauma.

[16]  Shumei S. Guo,et al.  CDC GROWTH CHARTS FOR THE UNITED STATES: METHODS AND DEVELOPMENT 2000 , 2002 .

[17]  Kathleen Desantis Klinich,et al.  Estimating infant head injury criteria and impact response using crash reconstruction and finite element modeling. , 2002, Stapp car crash journal.

[18]  Shumei S. Guo,et al.  2000 CDC Growth Charts for the United States: methods and development. , 2002, Vital and health statistics. Series 11, Data from the National Health Survey.

[19]  K.,et al.  FETAL HEAD MOLDING: AN INVESTIGATION UTILIZING A FINITE ELEMENT MODEL OF THE FETAL PARIETAL BONE* , 2003 .

[20]  L. F. Nazarian Pediatrics in Review : The Next Quarter Century , 2005 .

[21]  Rémy Willinger,et al.  Finite element analysis of impact and shaking inflicted to a child , 2007, International Journal of Legal Medicine.

[22]  Songbai Ji,et al.  Parametric study of head impact in the infant. , 2007, Stapp car crash journal.

[23]  Rémy Willinger,et al.  Biofidelic child head FE model to simulate real world trauma , 2008, Comput. Methods Programs Biomed..

[24]  Matthew B. Parkinson,et al.  MODELING VARIABILITY IN TORSO SHAPE FOR CHAIR AND SEAT DESIGN , 2008, DAC 2008.

[25]  Joel D Stitzel,et al.  Age and gender based biomechanical shape and size analysis of the pediatric brain. , 2008, Stapp car crash journal.

[26]  Rémy Willinger,et al.  Child head injury criteria investigation through numerical simulation of real world trauma , 2009, Comput. Methods Programs Biomed..

[27]  P. Gunz,et al.  The pattern of endocranial ontogenetic shape changes in humans , 2009, Journal of anatomy.

[28]  Barry S Myers,et al.  Pediatric head contours and inertial properties for ATD design. , 2010, Stapp car crash journal.

[29]  Rémy Willinger,et al.  Finite element modelling of paediatric head impact: Global validation against experimental data , 2010, Comput. Methods Programs Biomed..

[30]  Development, Validation, and Application of a Parametric Pediatric Head Finite Element Model for Impact Simulations , 2011, Annals of Biomedical Engineering.

[31]  S. Yamada,et al.  Developmental Anatomy of the Human Embryo – 3D-Imaging and Analytical Techniques , 2012 .

[32]  Matthew P. Reed,et al.  Erratum to: Development, Validation, and Application of a Parametric Pediatric Head Finite Element Model for Impact Simulations , 2012, Annals of Biomedical Engineering.

[33]  Matthew P. Reed,et al.  Erratum: Development, validation, and application of a parametric pediatric head finite element model for impact simulations (Annals of Biomedical Engineering (2011) 39:12 (2984-2997) DOI:10.1007/s10439-011-0409-z) , 2013 .

[34]  B. Guyer,et al.  Childhood Injuries in the United States , 2016 .