Vitamin D deficiency: a concern in pregnant Asian women

Vitamin D status of Asian mothers in Cardiff was investigated during early pregnancy and at the time of the birth of their babies, using serum parathyroid hormone (PTH). Median values in Asian (n 32) and Caucasian (n 63) mothers in early pregnancy were 1·56 and 0·81 pmol/1 respectively. PTH levels from a separate sample of nineteen Asian and twenty-five Caucasian mothers at the time of birth were 3·0 and 2·20 pmol/1 respectively. Altogether twelve Asian and two Caucasian women had elevated PTH. All Asian women who had high PTH values also had a very low serum 25-hydroxycholecalciferol level (25OHD). All samples were taken from women with no significant medical history and normal obstetric history. These findings suggest that subclinical vitamin D deficiency is still a cause for concern in Asian women. More active measures need to be taken to implement current recommendations to improve their vitamin D intake in pregnancy.

[1]  R. Brown,et al.  Renal Insufficiency and Secondary Hyperparathyroidism in Elderly Patients , 1991, Annals of clinical biochemistry.

[2]  K. Hulshof,et al.  Vitamin D status, parathyroid hormone and sunlight in Turkish, Moroccan and Caucasian children in The Netherlands. , 1990, European journal of clinical nutrition.

[3]  R. Brown,et al.  Measurement of circulating parathyroid hormone. , 1990, Hormone research.

[4]  E. Brown,et al.  Serum parathyroid hormone (PTH) in pregnant women determined by an immunoradiometric assay for intact PTH. , 1988, The Journal of clinical endocrinology and metabolism.

[5]  P. Dandona,et al.  Calcium, Vitamin D and Parathyroid Hormone Relationships in Pregnant Caucasian and Asian Women and Their Neonates , 1987, Annals of clinical biochemistry.

[6]  H. Grindulis,et al.  Combined deficiency of iron and vitamin D in Asian toddlers. , 1986, Archives of disease in childhood.

[7]  J. B. Henderson,et al.  Prevention of rickets in Asian children: assessment of the Glasgow campaign. , 1985, British medical journal.

[8]  O. Brooke,et al.  Intrauterine vitamin D nutrition and postnatal growth in Asian infants. , 1981, British medical journal.

[9]  J. Maxwell,et al.  Vitamin D supplements in pregnant Asian women: effects on calcium status and fetal growth. , 1980, British medical journal.

[10]  P. Walker,et al.  Nutritional osteomalacia and late rickets in Greater London, 1974--1979: clinical and metabolic studies in 45 patients. , 1980, Clinics in endocrinology and metabolism.

[11]  M. Peacock,et al.  PLASMA 25-HYDROXYVITAMIN D IN PREGNANT ASIAN WOMEN AND THEIR BABIES , 1979, The Lancet.

[12]  C. Berchel [Rickets and osteomalacia]. , 1977, Soins; la revue de reference infirmiere.

[13]  R. W. Logan,et al.  FLORID AND SUBCLINICAL RICKETS AMONG IMMIGRANT CHILDREN IN GLASGOW , 1976, The Lancet.

[14]  L. F. Hill,et al.  True fetal rickets. , 1974, The British journal of radiology.

[15]  D. Davidson,et al.  Neonatal rickets in Asian immigrant population. , 1973, British medical journal.

[16]  J. L. Taylor,et al.  Occult Rickets and Osteomalacia amongst the Asian Immigrant Population , 1973 .

[17]  J. A. Ford,et al.  Rickets and Osteomalacia in the Glasgow Pakistani Community, 1961-71 , 1972, British medical journal.