Do Cancer and Cancer Treatments Accelerate Aging?

[1]  P. Ganz,et al.  Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care , 2021, Nature Reviews Clinical Oncology.

[2]  Heather L. Mulder,et al.  Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. , 2020, Journal of the National Cancer Institute.

[3]  W. Wood,et al.  Accelerated aging among childhood, adolescent, and young adult cancer survivors is evidenced by increased expression of p16INK4a and frailty , 2020, Cancer.

[4]  M. Demaria,et al.  Senescent Cells in Cancer Therapy: Friends or Foes? , 2020, Trends in cancer.

[5]  J. Schrack,et al.  Strategies to Prevent or Remediate Cancer and Treatment-Related Aging. , 2020, Journal of the National Cancer Institute.

[6]  Mark A. LaBarge,et al.  How cancer therapeutics cause accelerated aging: Insights from the hallmarks of aging. , 2020, Journal of geriatric oncology.

[7]  P. Pressman,et al.  A review of nutrition and dietary interventions in oncology , 2020, SAGE open medicine.

[8]  P. Nathan,et al.  Prevalence and Predictors of Frailty in Childhood Cancer Survivors and Siblings: A Report From the Childhood Cancer Survivor Study. , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[9]  G. Winocur,et al.  Cancer-Related Cognitive Impairment: An update on state of the art, detection, and management strategies in cancer survivors. , 2019, Annals of oncology : official journal of the European Society for Medical Oncology.

[10]  L. Fried,et al.  Frailty: implications for clinical practice and public health , 2019, The Lancet.

[11]  T. Minamino,et al.  Cellular senescence in cardiac diseases. , 2019, Journal of cardiology.

[12]  P. Pedrazzoli,et al.  Whey protein isolate supplementation improves body composition, muscle strength, and treatment tolerance in malnourished advanced cancer patients undergoing chemotherapy , 2019, Cancer medicine.

[13]  E. Kleinerman,et al.  Vascular modulation through exercise improves chemotherapy efficacy in Ewing sarcoma , 2019, Pediatric blood & cancer.

[14]  G. Hubbard,et al.  How physically active do Australian and New Zealander childhood cancer survivors perceive themselves? A report from the ANZCHOG survivorship study. , 2019, Complementary therapies in medicine.

[15]  Janet S. Wright,et al.  Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors: A Scientific Statement From the American Heart Association. , 2019, Circulation.

[16]  Mellar P. Davis,et al.  Sarcopenia associated with chemotherapy and targeted agents for cancer therapy. , 2019, Annals of palliative medicine.

[17]  P. Marchetti,et al.  Clinical Impact of Highly Purified, Whey Proteins in Patients Affected With Colorectal Cancer Undergoing Chemotherapy: Preliminary Results of a Placebo-Controlled Study , 2019, Integrative cancer therapies.

[18]  K. Bhaskaran,et al.  Associations Between Breast Cancer Survivorship and Adverse Mental Health Outcomes: A Systematic Review , 2018, Journal of the National Cancer Institute.

[19]  V. Longo,et al.  Fasting and cancer: molecular mechanisms and clinical application , 2018, Nature Reviews Cancer.

[20]  L. Jones,et al.  Efficacy of Exercise Therapy on Cardiorespiratory Fitness in Patients With Cancer: A Systematic Review and Meta-Analysis. , 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  David D. Thomas,et al.  Age affects myosin relaxation states in skeletal muscle fibers of female but not male mice , 2018, bioRxiv.

[22]  Pornpimon Nunthanawanich,et al.  Whey Protein Supplementation Improves Nutritional Status, Glutathione Levels, and Immune Function in Cancer Patients: A Randomized, Double-Blind Controlled Trial. , 2018, Journal of medicinal food.

[23]  T. Tsai,et al.  Lactobacillus casei Variety rhamnosus Probiotic Preventively Attenuates 5-Fluorouracil/Oxaliplatin-Induced Intestinal Injury in a Syngeneic Colorectal Cancer Model , 2018, Front. Microbiol..

[24]  A. Michalsen,et al.  The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study , 2018, BMC cancer.

[25]  M. Resnick.  Re: The Cumulative Burden of Surviving Childhood Cancer: An Initial Report from the St Jude Lifetime Cohort Study (SJLIFE). , 2018, The Journal of urology.

[26]  M. Ferry,et al.  Association between cachexia, chemotherapy and outcomes in older cancer patients: A systematic review. , 2017, Clinical nutrition.

[27]  Kjetil Søreide,et al.  The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks , 2017, Aging and disease.

[28]  Ying Hou,et al.  Use of frailty to predict survival in elderly patients with early stage non-small-cell lung cancer treated with stereotactic body radiation therapy. , 2017, Journal of geriatric oncology.

[29]  Michael W. Bishop,et al.  Premature Ovarian Insufficiency in Childhood Cancer Survivors: A Report From the St. Jude Lifetime Cohort , 2017, The Journal of clinical endocrinology and metabolism.

[30]  S. Marzolini,et al.  The Cardiac Rehabilitation Model Improves Fitness, Quality of Life, and Depression in Breast Cancer Survivors , 2017, Journal of cardiopulmonary rehabilitation and prevention.

[31]  D. Ekwueme,et al.  Economic Burden of Chronic Conditions Among Survivors of Cancer in the United States. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[32]  Soumen Roy,et al.  Microbiota: a key orchestrator of cancer therapy , 2017, Nature Reviews Cancer.

[33]  P. Douglas,et al.  Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[34]  K. Ness,et al.  Frailty and quality of life in adult survivors of childhood cancer , 2017, Expert review of quality of life in cancer care.

[35]  R. Collins,et al.  Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation , 2016, Nature Medicine.

[36]  K. Ness,et al.  Physiologic Frailty in Nonelderly Hematopoietic Cell Transplantation Patients: Results From the Bone Marrow Transplant Survivor Study. , 2016, JAMA oncology.

[37]  L. Denehy,et al.  Functional and postoperative outcomes after preoperative exercise training in patients with lung cancer: a systematic review and meta-analysis. , 2016, Interactive cardiovascular and thoracic surgery.

[38]  Christopher S. Chen,et al.  Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy , 2016, Oncotarget.

[39]  G. Riscuta,et al.  Nutrigenomics at the Interface of Aging, Lifespan, and Cancer Prevention. , 2016, The Journal of nutrition.

[40]  C. Prado,et al.  Clinical Implications of Sarcopenic Obesity in Cancer , 2016, Current Oncology Reports.

[41]  M. Jensen,et al.  Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue , 2016, Diabetes.

[42]  Justin C. Brown,et al.  The Prognostic Importance of Frailty in Cancer Survivors , 2015, Journal of the American Geriatrics Society.

[43]  Gabriel A. Al-Ghalith,et al.  Chemotherapy‐driven dysbiosis in the intestinal microbiome , 2015, Alimentary pharmacology & therapeutics.

[44]  L. Jones,et al.  Cardiorespiratory fitness in survivors of cervical, endometrial, and ovarian cancers: The Cooper Center Longitudinal Study. , 2015, Gynecologic oncology.

[45]  S. Ravera,et al.  Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models , 2015, Oncotarget.

[46]  A. Ballestrero,et al.  Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition , 2015, Oncotarget.

[47]  Gregory Palmer,et al.  Modulation of Murine Breast Tumor Vascularity, Hypoxia, and Chemotherapeutic Response by Exercise , 2015, Journal of the National Cancer Institute.

[48]  P. Savage,et al.  Exercise-Based Oncology Rehabilitation: LEVERAGING THE CARDIAC REHABILITATION MODEL , 2015, Journal of cardiopulmonary rehabilitation and prevention.

[49]  D. McMillan,et al.  Routine clinical markers of the magnitude of the systemic inflammatory response after elective operation: a systematic review. , 2015, Surgery.

[50]  M. Joyner,et al.  Exercise attenuates the major hallmarks of aging. , 2015, Rejuvenation research.

[51]  C. Franceschi,et al.  Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. , 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

[52]  D. Siemann,et al.  Modulation of blood flow, hypoxia, and vascular function in orthotopic prostate tumors during exercise. , 2014, Journal of the National Cancer Institute.

[53]  J. Ibrahim,et al.  Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer. , 2014, Journal of the National Cancer Institute.

[54]  Mark P Mattson,et al.  Fasting: molecular mechanisms and clinical applications. , 2014, Cell metabolism.

[55]  L. Jones,et al.  Cardiorespiratory Fitness in Breast Cancer Patients: A Call for Normative Values , 2014, Journal of the American Heart Association.

[56]  S. Knuijt,et al.  Nutritional status, food intake, and dysphagia in long‐term survivors with head and neck cancer treated with chemoradiotherapy: A cross‐sectional study , 2014, Head & neck.

[57]  Carmen L. Wilson,et al.  Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[58]  S. Horvath.  DNA methylation age of human tissues and cell types , 2013, Genome Biology.

[59]  T. Morgan,et al.  Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression , 2013, Experimental Gerontology.

[60]  G. Rocco,et al.  High-intensity training and cardiopulmonary exercise testing in patients with chronic obstructive pulmonary disease and non-small-cell lung cancer undergoing lobectomy. , 2013, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[61]  C. Galet,et al.  Effects of Calorie Restriction and IGF-1 Receptor Blockade on the Progression of 22Rv1 Prostate Cancer Xenografts , 2013, International journal of molecular sciences.

[62]  Manuel Serrano,et al.  The Hallmarks of Aging , 2013, Cell.

[63]  B. Focht,et al.  Resistance exercise interventions during and following cancer treatment: a systematic review. , 2013, The journal of supportive oncology.

[64]  Angela M. Miller,et al.  Exercise capacity in long‐term survivors of pediatric cancer: An analysis from the cardiac risk factors in childhood cancer survivors study , 2013, Pediatric blood & cancer.

[65]  J. Campisi.  Aging, cellular senescence, and cancer. , 2013, Annual review of physiology.

[66]  Daniel Wuttke,et al.  The role of DNA methylation in aging, rejuvenation, and age-related disease. , 2012, Rejuvenation research.

[67]  Maria A. Woodward,et al.  Rapamycin slows aging in mice , 2012, Aging cell.

[68]  K. Courneya,et al.  Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[69]  D. Motola-Kuba,et al.  Gastrointestinal symptoms and weight loss in cancer patients receiving chemotherapy , 2012, British Journal of Nutrition.

[70]  A. Bartke,et al.  Rapamycin slows aging in mice , 2012, Cell cycle.

[71]  J. Sabate,et al.  Nutritional Status Affects Treatment Tolerability and Survival in Metastatic Colorectal Cancer Patients: Results of an AGEO Prospective Multicenter Study , 2012, Oncology.

[72]  D. Friedman,et al.  Cardiovascular Hospitalizations and Mortality Among Recipients of Hematopoietic Stem Cell Transplantation , 2011, Annals of Internal Medicine.

[73]  S. Mohile,et al.  Obese frailty, physical performance deficits, and falls in older men with biochemical recurrence of prostate cancer on androgen deprivation therapy: a case-control study. , 2011, Urology.

[74]  K. Ness,et al.  Physical performance limitations among adult survivors of childhood brain tumors , 2010, Cancer.

[75]  V. Longo,et al.  Calorie restriction and cancer prevention: metabolic and molecular mechanisms. , 2010, Trends in pharmacological sciences.

[76]  J. Campisi,et al.  The senescence-associated secretory phenotype: the dark side of tumor suppression. , 2010, Annual review of pathology.

[77]  J. Hoeijmakers.  DNA damage, aging, and cancer. , 2009, The New England journal of medicine.

[78]  N. Sharpless,et al.  Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human aging , 2009, Aging cell.

[79]  Jiahuai Han,et al.  Inflammatory signaling and cellular senescence. , 2009, Cellular signalling.

[80]  Corby K. Martin,et al.  Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss , 2009, PloS one.

[81]  J. Mackey,et al.  Early breast cancer therapy and cardiovascular injury. , 2007, Journal of the American College of Cardiology.

[82]  J. Mackey,et al.  Cardiovascular reserve and risk profile of postmenopausal women after chemoendocrine therapy for hormone receptor--positive operable breast cancer. , 2007, The oncologist.

[83]  H. Bartelink,et al.  Long-term risk of cardiovascular disease in 10-year survivors of breast cancer. , 2007, Journal of the National Cancer Institute.

[84]  S. Góźdź,et al.  Telomeres and telomerase in oncogenesis , 2006, Oncology letters.

[85]  J. Steinberger,et al.  Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study. , 2005, Blood.

[86]  B. Pinto,et al.  Riding the crest of the teachable moment: promoting long-term health after the diagnosis of cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[87]  D. Berrigan,et al.  Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. , 2003, Annual review of medicine.

[88]  S. Cho,et al.  Telomere length shortening in non-Hodgkin's lymphoma patients undergoing chemotherapy , 2003, Annals of Hematology.

[89]  Suzanne G. Leveille,et al.  Change in Muscle Strength Explains Accelerated Decline of Physical Function in Older Women With High Interleukin‐6 Serum Levels , 2002, Journal of the American Geriatrics Society.

[90]  Hong Xie,et al.  Effects of cisplatin on telomerase activity and telomere length in BEL-7404 human hepatoma cells , 2002, Cell Research.

[91]  C. Bloomfield,et al.  Leukemias and myelodysplastic syndromes secondary to drug, radiation, and environmental exposure. , 1992, Seminars in oncology.

[92]  J. Hankin,et al.  Role of diet in cancer incidence in Hawaii. , 1983, Cancer research.

[93]  A. McMichael,et al.  Patterns of gastro‐intestinal cancer in european migrants to Australia: The role of dietary change , 1980, International journal of cancer.

[94]  L. Jones,et al.  Cancer Treatment as an Accelerated Aging Process: Assessment, Biomarkers, and Interventions. , 2016, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

[95]  H. Cohen,et al.  Accelerated aging among cancer survivors: from pediatrics to geriatrics. , 2014, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

[96]  H. Naito,et al.  Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle , 2002, Pflügers Archiv.

[97]  S. Whitaker.  DNA damage by drugs and radiation: what is important and how is it measured? , 1992, European journal of cancer.