Animal Experimentation: A Guide to the Issues

An essential book for all those who conduct animal-based research or are involved in education and training, as well as regulators, supporters, and opponents alike. This fully updated third edition includes discussion of genetically altered animals and associated welfare and ethical issues that surround the breeding programmes in animal based research. The book discusses the origins of vivisection, the advances in human and non-human welfare made possible by animal experimentation, moral objections, and alternatives to the use of animals in research. It also examines the regulatory umbrella under which experiments are conducted in Europe, USA and Australasia. The author highlights the future responsibilities of researchers who will be working with animals, and offers practical advice on experimental design, literature search, consultation with colleagues, and the importance of the ongoing search for alternatives.

[1]  T. Regan.  The Case for Animal Rights , 1983 .

[2]  W. Russell,et al.  Ethical and Scientific Considerations Regarding Animal Testing and Research , 2011, PloS one.

[3]  V. Monamy,et al.  Opinion Practical and ethical considerations for students conducting ecological research involving wildlife , 2001 .

[4]  C. Bernard.  Medical Classic. (Book Reviews: An Introduction to the Study of Experimental Medicine) , 1957 .

[5]  James Brabazon.  Albert Schweitzer. A biography , 1975, Medical History.

[6]  Andrew N. Rowan,et al.  Of Mice, Models, and Men: A Critical Evaluation of Animal Research , 1984 .

[7]  K. Shimizu,et al.  Public attitudes toward animal research: some international comparisons. , 1994, Society & animals : social scientific studies of the human experience of other animals.

[8]  H. L. Jenkins,et al.  Progressive evaluation of skin irritancy of cosmetics using human volunteers , 1989, International journal of cosmetic science.

[9]  D. Morton.  The Scientist’s Responsibility for Refinement: A Guide to Better Animal Welfare and Better Science , 1989 .

[10]  T. Regan.  All that dwell therein : animal rights and environmental ethics , 1982 .

[11]  Richard D. French.  Antivivisection and Medical Science in Victorian Society , 1975 .

[12]  H. Selye.  The Stress of Life , 1958 .

[13]  M. Stephens.  MATERNAL DEPRIVATION: EXPERIMENTS IN PSYCHOLOGY A CRITIQUE OF ANIMAL MODELS , 1986 .

[14]  R. French.  Dissection and Vivisection in the European Renaissance , 1999 .

[15]  William D. M. Paton,et al.  Man and Mouse: Animals in Medical Research , 1984 .

[16]  Peter Singer,et al.  A companion to ethics , 1993 .

[17]  J. Burkhardt.  The inevitability of animal biotechnology? Ethics and the scientific attitude , 1998 .

[18]  G. Moberg,et al.  Biological response to stress: implications for animal welfare. , 2000 .

[19]  W. Shugg.  The Cartesian Beast-Machine in English Literature (1663-1750) , 1968 .

[20]  Hans Selye,et al.  Stress in Health and Disease , 1976 .

[21]  S. Flexner,et al.  The Transmission of Acute Poliomyelitis to Monkeys , 1909 .

[22]  Nicholas Humphrey,et al.  Consciousness Regained: Chapters in the Development of Mind , 1983 .

[23]  F. Bacon,et al.  The Advancement of Learning [1605] , 1949 .

[24]  R. Ryder,et al.  Animal Revolution: Changing Attitudes Towards Speciesism , 2001, Animal Welfare.

[25]  J. A. Fischer.  Taking Sympathy Seriously: A Defense of Our Moral Psychology Toward Animals , 1987 .

[26]  T. L. Scheid-Cook,et al.  A Sand County Almanac , 1949 .

[27]  Michael Balls,et al.  Controls on the care and use of experimental animals , 1998 .

[28]  C. Darwin.  The Descent of Man and Selection in Relation to Sex: INDEX , 1871 .

[29]  J. Bentham.  An Introduction to the Principles of Morals and Legislation , 1945, Princeton Readings in Political Thought.

[30]  R. Ryder,et al.  Victims of Science: The Use of Animals in Research , 1975 .

[31]  Stephen R. L. Clark,et al.  The Moral Status of Animals. , 1981 .

[32]  Peter R Sedgwick.  Lives in the balance: the ethics of using animals in biomedical research , 1994 .

[33]  P. Boyle.  The UFAW handbook on the care and management of cephalopods in the laboratory. , 1991 .

[34]  John H. Draize,et al.  METHODS FOR THE STUDY OF IRRITATION AND TOXICITY OF SUBSTANCES APPLIED TOPICALLY TO THE SKIN AND MUCOUS MEMBRANES , 1944 .

[35]  Carl Sagan,et al.  Shadows of Forgotten Ancestors: A Search for Who We Are , 1995 .

[36]  A. Schweitzer.  Civilization and ethics , 1929 .

[37]  S. Seidenari,et al.  In vitro testing of tensides employing monolayer cultures: a comparison with results of patch tests on human volunteers , 1999, Contact dermatitis.

[38]  Michael Balls,et al.  Recent progress toward reducing the use of animal experimentation in biomedical research , 1990 .

[39]  W. Shugg.  Humanitarian attitudes in the early animal experiments of the royal society , 1968 .

[40]  J. Howell,et al.  BOVINE GLYCOGENOSIS TYPE II. BIOCHEMICAL AND MORPHOLOGICAL CHARACTERISTICS OF SKELETAL MUSCLE IN CULTURE , 1984, Neuropathology and applied neurobiology.

[41]  P. Marler,et al.  Monkey responses to three different alarm calls: evidence of predator classification and semantic communication. , 1980, Science.

[42]  James Wong.  Laboratory Animal Care Policies and Regulations: Canada. , 1995, ILAR journal.

[43]  R. Adams.  The Plague Dogs , 1977 .

[44]  D. Morton,et al.  Laboratory Animal Care Policies and Regulations: United Kingdom. , 1995, ILAR journal.

[45]  Warren Thomas Reich.  Encyclopedia of Bioethics , 1979 .

[46]  D. Britt.  Ethics, ethical committees and animal experimentation , 1984, Nature.

[47]  Charles Birch,et al.  Regaining compassion for humanity and nature , 1993 .

[48]  W. Velander,et al.  Transgenic livestock as drug factories. , 1997, Scientific American.

[49]  D. H. Smyth,et al.  Alternatives to Animal Experiments , 1978 .

[50]  F. Robbins,et al.  Cultivation of the Lansing Strain of Poliomyelitis Virus in Cultures of Various Human Embryonic Tissues. , 1949, Science.

[51]  H. Herzog,et al.  Attitudes and Dispositional Optimism of Animal Rights Demonstrators , 1998 .

[52]  D. Morton,et al.  A systematic approach for establishing humane endpoints. , 2000, ILAR journal.

[53]  Holmes Rolston,et al.  Environmental Ethics: Duties to and Values in the Natural World , 1987 .

[54]  Sir William Paton.  Vivisection, morals, medicine: commentary from a vivisecting professor of pharmacology. , 1983, Journal of medical ethics.

[55]  J. B. Callicott.  In defense of the land ethic: essays in environmental philosophy , 1989 .

[56]  R. Downie.  Rights and Responsibilities in Modern Medicine , 1982 .

[57]  J. M. Weiss.  Psychological factors in stress and disease. , 1972, Scientific American.

[58]  D. Lonchamp,et al.  [Generalized glycogenosis (type II)]. , 1970, Les Cahiers de medecine.

[59]  A. Schweitzer,et al.  Dr. Schweitzer's Racism@@@Out of My Life and Thought: An Autobiography , 1949 .

[60]  A. Rowan,et al.  Animal Research—For and Against: A Philosophical, Social, and Historical Perspective , 2015, Perspectives in biology and medicine.

[61]  J. Sechzer,et al.  Animal Research and Ethical Conflict: An Analysis of the Scientific Literature: 1966–1986 , 1989 .

[62]  M. Stephens.  Replacing Animal Experiments , 1989 .

[63]  Albert Schinz,et al.  From Beast-Machine to Man-Machine , 1940 .

[64]  S. Garattini,et al.  The Importance of Animal Experimentation for Safety and Biomedical Research , 1990, Springer Netherlands.

[65]  A. Linzey,et al.  Political Theory and Animal Rights , 1991 .

[66]  H. Verhoog,et al.  [Ethical aspects of animal experimentation] , 1995, ALTEX.

[67]  Nicholaas A. Rupke.  Vivisection in historical perspective , 1987 .

[68]  Tom Regan,et al.  Animal rights and human obligations , 1989 .

[69]  Hamm Te,et al.  > Laboratory Animal Care Policies and Regulations: United States. , 1995 .

[70]  R. Rodd.  Biology, ethics, and animals , 1990 .

[71]  S. Wolfensohn,et al.  Handbook of Laboratory Animal Management and Welfare , 1994 .

[72]  A. Schweitzer,et al.  Indian thought and its development , 1951 .

[73]  J. Bentham,et al.  The collected works of Jeremy Bentham , 1968 .

[74]  R. Nash,et al.  Rights of Nature , 2019, Climate Change and the Voiceless.

[75]  D. Wilkins.  Animal Welfare In Europe, European Legislation And Concerns , 1997 .

[76]  H. Erickson,et al.  Animal pain : perception and alleviation , 1983 .

[77]  Peter Singer,et al.  In Defense of Animals , 1985 .

[78]  Derek A. Denton,et al.  The Pinnacle of Life: Consciousness and Self-Awareness in Humans and Animals , 1993 .

[79]  B. Rollin.  On telos and genetic engineering , 1998 .

[80]  D. Daly.  The Way In and the Way Out: François Magendie, Charles Bell and the Roots of the Spinal Nerves , 1975 .

[81]  P. H. Griffiths,et al.  Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment , 1985, Veterinary Record.

[82]  P. Hopkinson,et al.  Period of Adjustment of Rats used for Experimental Studies , 1971, Nature.

[83]  J. Cottingham.  ‘A Brute to the Brutes?’: Descartes' Treatment of Animals , 1978, Philosophy.

[84]  G. Langley.  Plea for a Sensitive Science , 1989 .

[85]  Thomas Hunt Morgan,et al.  The origin of species by natural selection. , 1925 .

[86]  David G. Porter,et al.  Ethical scores for animal experiments , 1992, Nature.

[87]  N. Wade.  New vaccine may bring man and chimpanzee into tragic conflict. , 1978, Science.

[88]  R. Nelson,et al.  Behavioral phenotyping of transgenic and knockout animals: a cautionary tale. , 2001, Lab animal.

[89]  Michelle Paver.  Legislation and regulation: a view from the UK , 1998 .

[90]  J. Turner.  Reckoning with the Beast: Animals, Pain, and Humanity in the Victorian Mind , 1980 .

[91]  D. Paterson,et al.  The Status of Animals: Ethics Education and Welfare , 1989 .

[92]  F. B. Orlans.  In the Name of Science: Issues in Responsible Animal Experimentation , 1993 .

[93]  D. Adams,et al.  Evidence for Pain and Suffering in Other Animals , 1989 .

[94]  Jacob Bronowski,et al.  Science and Human Values , 1956 .

[95]  M Mukerjee,et al.  Trends in animal research. , 1997, Scientific American.

[96]  C. Singer.  A SHORT HISTORY OF ANATOMY FROM THE GREEKS TO HARVEY , 1959 .

[97]  C. Bernard.  CLAUDE BERNARD: "AN INTRODUCTION TO THE STUDY OF EXPERIMENTAL MEDICINE. , 1965, The Medical journal of Australia.

[98]  A. A. Tuffery,et al.  Laboratory Animals: An Introduction for New Experimenters , 1987 .

[99]  A. Maehle,et al.  Animal experimentation from antiquity to the end of the Eighteenth Century: attitudes and arguments , 1987 .

[100]  B. Rollin,et al.  Animal Rights and Human Morality , 1981 .

[101]  William Harvey,et al.  Exercitatio anatomica de motu cordis et sanguinis in animalibus : being a facsimile of the 1628 Francofurti edition, together with the Keynes English translation of 1928 , 1978 .

[102]  K. Gärtner,et al.  Stress response of rats to handling and experimental procedures , 1980, Laboratory animals.

[103]  Michael Bliss,et al.  The Discovery of Insulin , 1982 .

[104]  G. Moberg,et al.  The Biology of Animal Stress: Basic Principles and Implications for Animal Welfare , 2000 .

[105]  Francis Bacon,et al.  The advancement of learning : a reproduction of the copy in the British Library owned by Charles I , 2018 .