Marchuk's Model of Immune System Dynamics with Application to Tumour Growth

Marchuk's model of a general immune reaction is presented in the paper. The results of investigation of the model are summarized. The qualitative behaviour of solutions to the model and its simplification is described. Many illustrations of recovery process, oscillations or lethal outcomes of a disease are shown. The model with time-dependent immune reactivity is also considered. Periodic dynamics caused by different reasons are compared.

[1]  Urszula Foryś Discrete mathematical model of an immune system , 1995 .

[2]  U. Forys Global analysis of marchuk's model in a case of weak immune system , 1997 .

[3]  Urszula Foryś,et al.  Periodic dynamics in a model of immune system , 2000 .

[4]  M Gesemann,et al.  Quantification of hepatitis B vaccine-induced antibodies as a predictor of anti-HBs persistence. , 1995, Vaccine.

[5]  U. an der Heiden,et al.  A basic mathematical model of the immune response. , 1995, Chaos.

[6]  Guriĭ Ivanovich Marchuk Mathematical models in immunology , 1983 .

[7]  Urszula Foryś GLOBAL ANALYSIS OF MARCZUK'S MODEL IN CASE OF STRONG IMMUNE SYSTEM , 2000 .

[8]  Complementary analysis of the initial value problem for a system of o.d.e. modelling the immune system after vaccinations , 2000 .

[10]  Ursula Forys,et al.  Interleukin mathematical model of an immune system , 1995 .

[11]  A. Perelson,et al.  Nonlinear dynamics of immunogenic tumors: parameter estimation and global bifurcation analysis. , 1994, Bulletin of mathematical biology.

[12]  Guriĭ Ivanovich Marchuk,et al.  Mathematical Modelling of Immune Response in Infectious Diseases , 1997 .

[13]  Urszula Foryś,et al.  Behaviour of Solutions to Marchuk's Model Depending on a Time Delay , 2000 .

[14]  D. Kirschner,et al.  Modeling immunotherapy of the tumor – immune interaction , 1998, Journal of mathematical biology.

[15]  Global analysis of the initial value problem for a system of O.D.E. modeling the immune system after vaccinations , 1999 .